Retinyl palmitate (BioDeep_00001867745)
Main id: BioDeep_00000004948
PANOMIX_OTCML-2023 BioNovoGene_Lab2019
代谢物信息卡片
Vitamin a palmitate
化学式: C36H60O2 (524.459306)
中文名称: 维生素A棕榈酸酯, 视黄醇棕榈酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(/C=C/C=C(/C=C/C1=C(CCCC(C)1C)C)C)=C\COC(CCCCCCCCCCCCCCC)=O
InChI: InChI=1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+
描述信息
C274 - Antineoplastic Agent > C2122 - Cell Differentiating Agent > C1934 - Differentiation Inducer
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C804 - Retinoic Acid Agent
C308 - Immunotherapeutic Agent > C129820 - Antineoplastic Immunomodulating Agent
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
D020011 - Protective Agents > D016588 - Anticarcinogenic Agents
D000970 - Antineoplastic Agents
Retinyl palmitate is an ester of Retinol and is the major form of vitamin A found in the epidermis. Retinyl palmitate has been widely used in pharmaceutical and cosmetic formulations.
同义名列表
3 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:17616
- ChEBI: CHEBI:15040
- KEGG: C02588
- KEGG: C76552
- KEGGdrug: D00164
- PubChem: 5280531
- ChEMBL: CHEMBL1675
- CAS: 79-81-2
- PubChem: 5580
- LipidMAPS: LMPR01090013
- 3DMET: B00464
- NIKKAJI: J3.849K
- medchemexpress: HY-B1384
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-614
分类词条
相关代谢途径
Reactome(9)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Y R Hao, S Y Li, J Y Bao, J Y Wang, A Li, L Tian, Y Jie. [Efficacy of 0.05\% cyclosporine A combined with vitamin A palmitate in the treatment of meibomian gland dysfunction-related dry eye].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology.
2024 Feb; 60(2):127-136. doi:
10.3760/cma.j.cn112142-20231109-00221. [PMID: 38296318] - Gerhard G Rimkus, Martin Schubert, David Morgan, Svenja Jungjohann. Rapid direct analysis of retinyl palmitate (vitamin A) in fortified vegetable oils by HPLC-FLD.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2022 Jan; 39(1):24-34. doi:
10.1080/19440049.2021.1977854. [PMID: 34587464] - Zhe-Yu Yang, Wei-Liang Chen. Physiological significance of link between polycyclic aromatic hydrocarbons and serum nutritional biomarkers.
Food chemistry.
2021 Aug; 353(?):129445. doi:
10.1016/j.foodchem.2021.129445. [PMID: 33714110] - Yunbing Tan, Hualu Zhou, Zhiyun Zhang, David Julian McClements. Bioaccessibility of oil-soluble vitamins (A, D, E) in plant-based emulsions: impact of oil droplet size.
Food & function.
2021 May; 12(9):3883-3897. doi:
10.1039/d1fo00347j. [PMID: 33978004] - Eline Van Wayenbergh, Nore Struyf, Mohammad N Rezaei, Laurent Sagalowicz, Rachid Bel-Rhlid, Cyril Moccand, Christophe M Courtin. Cereal bran protects vitamin A from degradation during simmering and storage.
Food chemistry.
2020 Nov; 331(?):127292. doi:
10.1016/j.foodchem.2020.127292. [PMID: 32559599] - Ricardo Melo de Carvalho, Marcus Vinicius Oliveira Barros de Alencar, Ana Maria Oliveira Ferreira da Mata, Rosália Maria Tôrres de Lima, Rai Pablo Sousa de Aguiar, Jadson Silva Teixeira, Márcia Fernanda Correia Jardim Paz, Soane Kaline Morais Chaves, Muhammad Torequl Islam, João Marcelo de Castro E Sousa, Paulo Michel Pinheiro Ferreira, Ana Amélia de Carvalho Melo Cavalcante, Bahare Salehi, William N Setzer, Javad Sharifi-Rad. Retinol palmitate against toxicogenic damages of antineoplastic drugs on normal and tumor cells.
Chemico-biological interactions.
2020 Oct; 330(?):109219. doi:
10.1016/j.cbi.2020.109219. [PMID: 32846153] - Ali Saeed, Joanne A Hoogerland, Hanna Wessel, Janette Heegsma, Terry G J Derks, Eveline van der Veer, Gilles Mithieux, Fabienne Rajas, Maaike H Oosterveer, Klaas Nico Faber. Glycogen storage disease type 1a is associated with disturbed vitamin A metabolism and elevated serum retinol levels.
Human molecular genetics.
2020 01; 29(2):264-273. doi:
10.1093/hmg/ddz283. [PMID: 31813960] - Nehali Patel, Rhiannon R Penkert, Bart G Jones, Robert E Sealy, Sherri L Surman, Yilun Sun, Li Tang, Jennifer DeBeauchamp, Ashley Webb, Julie Richardson, Ryan Heine, Ronald H Dallas, A Catharine Ross, Richard Webby, Julia L Hurwitz. Baseline Serum Vitamin A and D Levels Determine Benefit of Oral Vitamin A&D Supplements to Humoral Immune Responses Following Pediatric Influenza Vaccination.
Viruses.
2019 09; 11(10):. doi:
10.3390/v11100907. [PMID: 31575021] - S A Tanumihardjo, B M Gannon, C Kaliwile, J Chileshe, N C Binkley. Restricting vitamin A intake increases bone formation in Zambian children with high liver stores of vitamin.
Archives of osteoporosis.
2019 06; 14(1):72. doi:
10.1007/s11657-019-0617-y. [PMID: 31254130] - Marcela Martins Soares, Mariane Alves Silva, Pauliana Pimentel Coelho Garcia, Luciana Saraiva da Silva, Glauce Dias da Costa, Raquel Maria Amaral Araújo, Rosângela Minardi Mitre Cotta. Efect of vitamin A suplementation: a systematic review.
Ciencia & saude coletiva.
2019 Mar; 24(3):827-838. doi:
10.1590/1413-81232018243.07112017. [PMID: 30892504] - Sama Bitarafan, Zinat Mohammadpour, Sima Jafarirad, Mohammad-Hossein Harirchian, Mir Saeed Yekaninejad, Ali Akbar Saboor-Yaraghi. The effect of retinyl-palmitate on the level of pro and anti-inflammatory cytokines in multiple sclerosis patients: A randomized double blind clinical trial.
Clinical neurology and neurosurgery.
2019 02; 177(?):101-105. doi:
10.1016/j.clineuro.2019.01.003. [PMID: 30640138] - Pedro Espitia-Pérez, Suelen Marin Albino, Helen Tais da Rosa, Alexandre Kleber Silveira, Lyda Espitia-Pérez, Hugo Brango, Diogo Pompéu Moraes, Paolla Rissi Silva Hermann, Moara Mingori, Fabiano Barreto, Alice Kunzler, Daniel Pens Gelain, Carlos Eduardo Schnorr, José Cláudio Fonseca Moreira. Effects of methylmercury and retinol palmitate co-administration in rats during pregnancy and breastfeeding: Metabolic and redox parameters in dams and their offspring.
Ecotoxicology and environmental safety.
2018 Oct; 162(?):603-615. doi:
10.1016/j.ecoenv.2018.06.093. [PMID: 30031321] - Antonio Lima Braga, Ag-Anne Pereira Melo de Meneses, José Victor de Oliveira Santos, Antonielly Campinho Dos Reis, Rosália Maria Tôrres de Lima, Ana Maria Oliveira Ferreira da Mata, Márcia Fernanda Correia Jardim Paz, Leane Brunelle Dos Santos Alves, Subrata Shaw, Shaikh Jamal Uddin, Razina Rouf, Asish Kumar Das, Shrabanti Dev, Manik Chandra Shil, Jamil A Shilpi, Ishaq N Khan, Muhammad Torequl Islam, Eunüs S Ali, Mohammad S Mubarak, Siddhartha Kumar Mishra, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo-Cavalcante. Toxicogenetic study of omeprazole and the modulatory effects of retinol palmitate and ascorbic acid on Allium cepa.
Chemosphere.
2018 08; 204(?):220-226. doi:
10.1016/j.chemosphere.2018.04.021. [PMID: 29656158] - Charles Desmarchelier, Véronique Rosilio, David Chapron, Ali Makky, Damien P Prévéraud, Estelle Devillard, Véronique Legrand-Defretin, Patrick Borel. Molecular interactions governing the incorporation of cholecalciferol and retinyl-palmitate in mixed taurocholate-lipid micelles.
Food chemistry.
2018 Jun; 250(?):221-229. doi:
10.1016/j.foodchem.2018.01.063. [PMID: 29412915] - Angelica M Gutierrez, Terri D Boylston, Stephanie Clark. Effects of Pro-Oxidants and Antioxidants on the Total Antioxidant Capacity and Lipid Oxidation Products of Milk During Refrigerated Storage.
Journal of food science.
2018 Feb; 83(2):275-283. doi:
10.1111/1750-3841.14016. [PMID: 29243810] - Elisabetta Esposito, Alessandra Pecorelli, Maddalena Sguizzato, Markus Drechsler, Paolo Mariani, Federica Carducci, Franco Cervellati, Claudio Nastruzzi, Rita Cortesi, Giuseppe Valacchi. Production and Characterization of Nanoparticle Based Hyaluronate Gel Containing Retinyl Palmitate for Wound Healing.
Current drug delivery.
2018; 15(8):1172-1182. doi:
10.2174/1567201815666180518123926. [PMID: 29779480] - Mohsen Mazidi, Nathan D Wong, Niki Katsiki, Dimitri P Mikhailidis, Maciej Banach. Dietary patterns, plasma vitamins and Trans fatty acids are associated with peripheral artery disease.
Lipids in health and disease.
2017 Dec; 16(1):254. doi:
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The American journal of clinical nutrition.
2017 Oct; 106(4):1041-1051. doi:
10.3945/ajcn.117.153635. [PMID: 28814399] - Jessica L Cooperstone, Hilary J Goetz, Ken M Riedl, Earl H Harrison, Steven J Schwartz, Rachel E Kopec. Relative contribution of α-carotene to postprandial vitamin A concentrations in healthy humans after carrot consumption.
The American journal of clinical nutrition.
2017 Jul; 106(1):59-66. doi:
10.3945/ajcn.116.150821. [PMID: 28515067] - Joanna K Hodges, Libo Tan, Michael H Green, A Catharine Ross. Vitamin A supplementation redirects the flow of retinyl esters from peripheral to central organs of neonatal rats raised under vitamin A-marginal conditions.
The American journal of clinical nutrition.
2017 05; 105(5):1110-1121. doi:
10.3945/ajcn.116.149039. [PMID: 28298391] - Chuan Li, Masahiko Imai, Masahiro Yamasaki, Shinya Hasegawa, Noriko Takahashi. Effects of Pre- and Post-Administration of Vitamin A on the Growth of Refractory Cancers in Xenograft Mice.
Biological & pharmaceutical bulletin.
2017 Apr; 40(4):486-494. doi:
10.1248/bpb.b16-00933. [PMID: 28100867] - Hiroshi Toshida, Toshinari Funaki, Koichi Ono, Nobuhito Tabuchi, Sota Watanabe, Tamotsu Seki, Hiroshi Otake, Takuji Kato, Nobuyuki Ebihara, Akira Murakami. Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial.
Drug design, development and therapy.
2017; 11(?):1871-1879. doi:
10.2147/dddt.s137825. [PMID: 28694687] - Silvia Rocchi, Fulvia Caretti, Alessandra Gentili, Roberta Curini, Daniela Perret, Virginia Pérez-Fernández. Quantitative profiling of retinyl esters in milk from different ruminant species by using high performance liquid chromatography-diode array detection-tandem mass spectrometry.
Food chemistry.
2016 Nov; 211(?):455-64. doi:
10.1016/j.foodchem.2016.05.066. [PMID: 27283655] - E C Grilo, W F Medeiros, A G A Silva, C S S Gurgel, H M M Ramalho, R Dimenstein. Maternal supplementation with a megadose of vitamin A reduces colostrum level of α-tocopherol: a randomised controlled trial.
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.
2016 10; 29(5):652-61. doi:
10.1111/jhn.12381. [PMID: 27231056] - Joanna K Hodges, Libo Tan, Michael H Green, A Catharine Ross. Vitamin A Supplementation Transiently Increases Retinol Concentrations in Extrahepatic Organs of Neonatal Rats Raised under Vitamin A-Marginal Conditions.
The Journal of nutrition.
2016 Oct; 146(10):1953-1960. doi:
10.3945/jn.116.234310. [PMID: 27534819] - Amanda C Palmer, Justin Chileshe, Andrew G Hall, Maxwell A Barffour, Ngosa Molobeka, Keith P West, Marjorie J Haskell. Short-Term Daily Consumption of Provitamin A Carotenoid-Biofortified Maize Has Limited Impact on Breast Milk Retinol Concentrations in Zambian Women Enrolled in a Randomized Controlled Feeding Trial.
The Journal of nutrition.
2016 09; 146(9):1783-92. doi:
10.3945/jn.116.233700. [PMID: 27466608] - Hilary J Goetz, Rachel E Kopec, Ken M Riedl, Jessica L Cooperstone, Sureshbabu Narayanasamy, Robert W Curley, Steven J Schwartz. An HPLC-MS/MS method for the separation of α-retinyl esters from retinyl esters.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Sep; 1029-1030(?):68-71. doi:
10.1016/j.jchromb.2016.06.043. [PMID: 27423669] - Joanna K Hodges, Libo Tan, Michael H Green, A Catharine Ross. Vitamin A Supplementation Increases the Uptake of Chylomicron Retinyl Esters into the Brain of Neonatal Rats Raised under Vitamin A-Marginal Conditions.
The Journal of nutrition.
2016 09; 146(9):1677-83. doi:
10.3945/jn.116.233692. [PMID: 27511933] - Tomomi Shirai, Yuta Shichi, Miyuki Sato, Yuri Tanioka, Tadasu Furusho, Toru Ota, Tadahiro Tadokoro, Tsukasa Suzuki, Ken-Ichi Kobayashi, Yuji Yamamoto. High dietary fat-induced obesity in Wistar rats and type 2 diabetes in nonobese Goto-Kakizaki rats differentially affect retinol binding protein 4 expression and vitamin A metabolism.
Nutrition research (New York, N.Y.).
2016 Mar; 36(3):262-70. doi:
10.1016/j.nutres.2015.11.018. [PMID: 26923513] - Yachana Kataria, Ryan J Deaton, Erika Enk, Ming Jin, Milita Petrauskaite, Linlin Dong, Joseph R Goldenberg, Scott J Cotler, Donald M Jensen, Richard B van Breemen, Peter H Gann. Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer.
BMC gastroenterology.
2016 Feb; 16(?):30. doi:
10.1186/s12876-016-0432-5. [PMID: 26927700] - Gabriela Monico, Micheal Leo, Brian Ma, Ritika S Johal, Thomas Ma, Raja K Sivamani. The use of botanical products and vitamins in sunscreens.
Dermatology online journal.
2015 Nov; 21(11):. doi:
". [PMID: 26632925] - Chenghao Zhu, Yimeng Cai, Erik R Gertz, Michael R La Frano, Dustin J Burnett, Betty J Burri. Red palm oil-supplemented and biofortified cassava gari increase the carotenoid and retinyl palmitate concentrations of triacylglycerol-rich plasma in women.
Nutrition research (New York, N.Y.).
2015 Nov; 35(11):965-74. doi:
10.1016/j.nutres.2015.08.003. [PMID: 26319612] - Sandjaja, Idrus Jus'at, Abas B Jahari, Ifrad, Min Kyaw Htet, Robert L Tilden, Damayanti Soekarjo, Budi Utomo, Regina Moench-Pfanner, Soekirman, Eline L Korenromp. Vitamin A-fortified cooking oil reduces vitamin A deficiency in infants, young children and women: results from a programme evaluation in Indonesia.
Public health nutrition.
2015 Oct; 18(14):2511-22. doi:
10.1017/s136898001400322x. [PMID: 25591926] - Carlos Eduardo Schnorr, Leonardo da Silva Bittencourt, Lyvia Lintzmaier Petiz, Daniel Pens Gelain, Fares Zeidán-Chuliá, José Cláudio Fonseca Moreira. Chronic retinyl palmitate supplementation to middle-aged Wistar rats disrupts the brain redox homeostasis and induces changes in emotional behavior.
Molecular nutrition & food research.
2015 May; 59(5):979-90. doi:
10.1002/mnfr.201400637. [PMID: 25676740] - Gabriela Villaça Chaves, Wilza Arantes Ferreira Peres, José Carlos Gonçalves, Andréa Ramalho. Vitamin A and retinol-binding protein deficiency among chronic liver disease patients.
Nutrition (Burbank, Los Angeles County, Calif.).
2015 May; 31(5):664-8. doi:
10.1016/j.nut.2014.10.016. [PMID: 25837210] - Maitreyi Raman, Tanis Fenton, Pam Crotty, Subrata Ghosh, Kevin Rioux, Rajveer Hundal. A novel method to identify fat malabsorption: the Serum Retinyl Palmitate Test.
Clinica chimica acta; international journal of clinical chemistry.
2015 Jan; 438(?):103-6. doi:
10.1016/j.cca.2014.08.001. [PMID: 25110812] - Evellyn C Grilo, Mayara S R Lima, Lahyana R F Cunha, Cristiane S S Gurgel, Heleni A Clemente, Roberto Dimenstein. Effect of maternal vitamin A supplementation on retinol concentration in colostrum.
Jornal de pediatria.
2015 Jan; 91(1):81-6. doi:
10.1016/j.jped.2014.05.004. [PMID: 25193595] - A C Longardt, B Schmiedchen, J Raila, F J Schweigert, M Obladen, C Bührer, A Loui. Characterization of the vitamin A transport in preterm infants after repeated high-dose vitamin A injections.
European journal of clinical nutrition.
2014 Dec; 68(12):1300-4. doi:
10.1038/ejcn.2014.202. [PMID: 25315494] - Beatriz Clares, Ana C Calpena, Alexander Parra, Guadalupe Abrego, Helen Alvarado, Joana F Fangueiro, Eliana B Souto. Nanoemulsions (NEs), liposomes (LPs) and solid lipid nanoparticles (SLNs) for retinyl palmitate: effect on skin permeation.
International journal of pharmaceutics.
2014 Oct; 473(1-2):591-8. doi:
10.1016/j.ijpharm.2014.08.001. [PMID: 25102113] - Carlo Pirazzi, Luca Valenti, Benedetta Maria Motta, Piero Pingitore, Kristina Hedfalk, Rosellina Margherita Mancina, Maria Antonella Burza, Cesare Indiveri, Yvelise Ferro, Tiziana Montalcini, Cristina Maglio, Paola Dongiovanni, Silvia Fargion, Raffaela Rametta, Arturo Pujia, Linda Andersson, Saswati Ghosal, Malin Levin, Olov Wiklund, Michelina Iacovino, Jan Borén, Stefano Romeo. PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells.
Human molecular genetics.
2014 Aug; 23(15):4077-85. doi:
10.1093/hmg/ddu121. [PMID: 24670599] - Anamthathmakula Prashanth, Shanmugam M Jeyakumar, Nappan V Giridharan, Ayyalasomayajula Vajreswari. Vitamin A-enriched diet modulates reverse cholesterol transport in hypercholesterolemic obese rats of the WNIN/Ob strain.
Journal of atherosclerosis and thrombosis.
2014; 21(11):1197-207. doi:
10.5551/jat.22186. [PMID: 25100235] - Linda Butler Thompson, Karen Schimpf, Steve Baugh. Determination of vitamins A and E in infant formula and adult/pediatric nutritional formula by HPLC with UV and fluorescence detection: First Action 2012.09.
Journal of AOAC International.
2013 Nov; 96(6):1407-13. doi:
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International journal of pharmaceutics.
2013 Aug; 452(1-2):311-20. doi:
10.1016/j.ijpharm.2013.05.023. [PMID: 23702002] - Ellie Souganidis, Arnaud Laillou, Magali Leyvraz, Regina Moench-Pfanner. A comparison of retinyl palmitate and red palm oil β-carotene as strategies to address Vitamin A deficiency.
Nutrients.
2013 Aug; 5(8):3257-71. doi:
10.3390/nu5083257. [PMID: 23955382] - Michael R La Frano, Leslie R Woodhouse, Dustin J Burnett, Betty J Burri. Biofortified cassava increases β-carotene and vitamin A concentrations in the TAG-rich plasma layer of American women.
The British journal of nutrition.
2013 Jul; 110(2):310-20. doi:
10.1017/s0007114512005004. [PMID: 23332040] - Mathias J Jørgensen, Ane B Fisker, Erliyani Sartono, Andreas Andersen, Christian Erikstrup, Ida M Lisse, Maria Yazdanbakhsh, Peter Aaby, Christine S Benn. The effect of at-birth vitamin A supplementation on differential leucocyte counts and in vitro cytokine production: an immunological study nested within a randomised trial in Guinea-Bissau.
The British journal of nutrition.
2013 Feb; 109(3):467-77. doi:
10.1017/s0007114512001304. [PMID: 23168172] - Abdulkadi Levent, Gokhan Oto, Suat Ekin, Ismet Berber. Method validation and simultaneous determination of retinol, retinyl palmitate, β-carotene, α-tocopherol and vitamin C in rat serum treated with 7,12 dimethylbenz[a]anthracene and Plantago major L. by high- performance liquid chromatography using diode-array detection.
Combinatorial chemistry & high throughput screening.
2013 Feb; 16(2):142-9. doi:
. [PMID: 23176060] - Jonathan Verreault, Lisa B Helgason, Geir W Gabrielsen, Maria Dam, Birgit M Braune. Contrasting retinoid and thyroid hormone status in differentially-contaminated northern fulmar colonies from the Canadian Arctic, Svalbard and the Faroe Islands.
Environment international.
2013 Feb; 52(?):29-40. doi:
10.1016/j.envint.2012.12.001. [PMID: 23280374] - Mahdieh Abbasalizad Farhangi, Seyyed Ali Keshavarz, Mohammadreza Eshraghian, Alireza Ostadrahimi, Ali Akbar Saboor-Yaraghi. Vitamin A supplementation, serum lipids, liver enzymes and C-reactive protein concentrations in obese women of reproductive age.
Annals of clinical biochemistry.
2013 Jan; 50(Pt 1):25-30. doi:
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Journal of the American College of Nutrition.
2013; 32(4):280-5. doi:
10.1080/07315724.2013.816616. [PMID: 24024773] - Anta Agne-Djigo, Nicole Idohou-Dossou, Komlan M Kwadjode, Sherry A Tanumihardjo, Salimata Wade. High prevalence of vitamin A deficiency is detected by the modified relative dose-response test in six-month-old Senegalese breast-fed infants.
The Journal of nutrition.
2012 Nov; 142(11):1991-6. doi:
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The American journal of clinical nutrition.
2012 Oct; 96(4):932-40. doi:
10.3945/ajcn.112.035725. [PMID: 22952182] - L S Mortensen, J Holmer-Jensen, M L Hartvigsen, V K Jensen, A Astrup, M de Vrese, J J Holst, C Thomsen, K Hermansen. Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes.
European journal of clinical nutrition.
2012 Jul; 66(7):799-805. doi:
10.1038/ejcn.2012.48. [PMID: 22588635] - A Galler, J L Tran, S Krammer-Lukas, U Höller, J G Thalhammer, J Zentek, M Willmann. Blood vitamin levels in dogs with chronic kidney disease.
Veterinary journal (London, England : 1997).
2012 May; 192(2):226-31. doi:
10.1016/j.tvjl.2011.06.026. [PMID: 21767966] - Mathias Jul Jørgensen, Ane Bærent Fisker, Christian Erikstrup, Mogens H Claesson, Christine Stabell Benn. SNP may modify the effect of vitamin A supplementation at birth on cytokine production in a whole blood culture assay.
The British journal of nutrition.
2012 Mar; 107(5):615-20. doi:
10.1017/s0007114511003515. [PMID: 21791141] - Adriana A Pereira, Bert van Hattum, Abraham Brouwer. Hepatic retinoid levels in seven fish species (teleosts) from a tropical coastal lagoon receiving effluents from iron-ore mining and processing.
Environmental toxicology and chemistry.
2012 Feb; 31(2):408-16. doi:
10.1002/etc.740. [PMID: 22095865] - Manuel Gesto, L Filipe C Castro, Maria Armanda Reis-Henriques, Miguel Machado Santos. Tissue-specific distribution patterns of retinoids and didehydroretinoids in rainbow trout Oncorhynchus mykiss.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
2012 Jan; 161(1):69-78. doi:
10.1016/j.cbpb.2011.09.006. [PMID: 21946003] - Raju Marisiddaiah, Lakshminarayana Rangaswamy, Baskaran Vallikannan. Single oral dose of micellar β-carotene containing phospholipids improves β-carotene metabolism and plasma lipids in vitamin A-deficient rats.
European journal of nutrition.
2011 Oct; 50(7):531-41. doi:
10.1007/s00394-010-0160-5. [PMID: 21188595] - Olga Nikolaeva, Gennadiy Moiseyev, Karla K Rodgers, Jian-Xing Ma. Binding to lipid membrane induces conformational changes in RPE65: implications for its isomerohydrolase activity.
The Biochemical journal.
2011 Jun; 436(3):591-7. doi:
10.1042/bj20110091. [PMID: 21446919] - Roberto Dimenstein, Larissa Lira, Ana C P Medeiros, Lahyana R F Cunha, Tânia L M Stamford. [Effect of vitamin E supplementation on alpha-tocopherol levels in human colostrum].
Revista panamericana de salud publica = Pan American journal of public health.
2011 Jun; 29(6):399-403. doi:
NULL. [PMID: 21829962] - Keith P West, Parul Christian, Alain B Labrique, Mahbubur Rashid, Abu Ahmed Shamim, Rolf D W Klemm, Allan B Massie, Sucheta Mehra, Kerry J Schulze, Hasmot Ali, Barkat Ullah, Lee S F Wu, Joanne Katz, Hashina Banu, Halida H Akhter, Alfred Sommer. Effects of vitamin A or beta carotene supplementation on pregnancy-related mortality and infant mortality in rural Bangladesh: a cluster randomized trial.
JAMA.
2011 May; 305(19):1986-95. doi:
10.1001/jama.2011.656. [PMID: 21586714] - Matheus Augusto de Bittencourt Pasquali, Carlos Eduardo Schnorr, Lucas Brambilla Hilbig Feistauer, Daniel Pens Gelain, José Cláudio Fonseca Moreira. Vitamin A supplementation to pregnant and breastfeeding female rats induces oxidative stress in the neonatal lung.
Reproductive toxicology (Elmsford, N.Y.).
2010 Nov; 30(3):452-6. doi:
10.1016/j.reprotox.2010.05.085. [PMID: 20679000] - Josef Dvorák, Bohuslav Melichar, Radomír Hyspler, Lenka Krcmová, Lubor Urbánek, Hana Kalábová, Markéta Kasparová, Dagmar Solichová. Intestinal permeability, vitamin A absorption, alpha-tocopherol, and neopterin in patients with rectal carcinoma treated with chemoradiation.
Medical oncology (Northwood, London, England).
2010 Sep; 27(3):690-6. doi:
10.1007/s12032-009-9270-4. [PMID: 19629763] - Ting Fang Lee, Ki M Mak, Ori Rackovsky, Yun-Lian Lin, Allison J Kwong, Johnny C Loke, Scott L Friedman. Downregulation of hepatic stellate cell activation by retinol and palmitate mediated by adipose differentiation-related protein (ADRP).
Journal of cellular physiology.
2010 Jun; 223(3):648-57. doi:
10.1002/jcp.22063. [PMID: 20143336] - Carolien A Van Loo-Bouwman, Ton H J Naber, Richard B van Breemen, Dongwei Zhu, Heleen Dicke, Els Siebelink, Paul J M Hulshof, Frans G M Russel, Gertjan Schaafsma, Clive E West. Vitamin A equivalency and apparent absorption of beta-carotene in ileostomy subjects using a dual-isotope dilution technique.
The British journal of nutrition.
2010 Jun; 103(12):1836-43. doi:
10.1017/s0007114509993849. [PMID: 20132586] - Alexander R Moise, Glenn P Lobo, Bernadette Erokwu, David L Wilson, David Peck, Susana Alvarez, Marta Domínguez, Rosana Alvarez, Chris A Flask, Angel R de Lera, Johannes von Lintig, Krzysztof Palczewski. Increased adiposity in the retinol saturase-knockout mouse.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2010 Apr; 24(4):1261-70. doi:
10.1096/fj.09-147207. [PMID: 19940255] - L Brader, L Holm, L Mortensen, C Thomsen, A Astrup, J J Holst, M de Vrese, J Schrezenmeir, K Hermansen. Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects.
Nutrition, metabolism, and cardiovascular diseases : NMCD.
2010 Feb; 20(2):101-9. doi:
10.1016/j.numecd.2009.03.019. [PMID: 19473824] - Anna Gronowska-Senger, Katarzyna Burzykowska, Magdalena Przepiórka. [Retinyl palmitate and oxidative stress reduction in rats].
Roczniki Panstwowego Zakladu Higieny.
2010; 61(1):21-5. doi:
". [PMID: 20803896] - Davide Noto, Angelo B Cefalù, Alessandra Cannizzaro, Mariangela Minà, Francesca Fayer, Vincenza Valenti, Carlo M Barbagallo, Antonino Tuttolomondo, Antonio Pinto, Carmelo Sciumè, Giuseppe Licata, Maurizio Averna. Familial hypobetalipoproteinemia due to apolipoprotein B R463W mutation causes intestinal fat accumulation and low postprandial lipemia.
Atherosclerosis.
2009 Sep; 206(1):193-8. doi:
10.1016/j.atherosclerosis.2009.01.037. [PMID: 19344897] - Raju Marisiddaiah, Vallikannan Baskaran. Bioefficacy of beta-carotene is improved in rats after solubilized as equimolar dose of beta-carotene and lutein in phospholipid-mixed micelles.
Nutrition research (New York, N.Y.).
2009 Aug; 29(8):588-95. doi:
10.1016/j.nutres.2009.07.005. [PMID: 19761893] - Lene S Mortensen, Merete L Hartvigsen, Lea J Brader, Arne Astrup, Jürgen Schrezenmeir, Jens J Holst, Claus Thomsen, Kjeld Hermansen. Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein.
The American journal of clinical nutrition.
2009 Jul; 90(1):41-8. doi:
10.3945/ajcn.2008.27281. [PMID: 19458012] - Olga Nikolaeva, Yusuke Takahashi, Gennadiy Moiseyev, Jian-Xing Ma. Purified RPE65 shows isomerohydrolase activity after reassociation with a phospholipid membrane.
The FEBS journal.
2009 Jun; 276(11):3020-30. doi:
10.1111/j.1742-4658.2009.07021.x. [PMID: 19490105] - Emmanuelle Reboul, Doriane Trompier, Myriam Moussa, Alexis Klein, Jean-François Landrier, Giovanna Chimini, Patrick Borel. ATP-binding cassette transporter A1 is significantly involved in the intestinal absorption of alpha- and gamma-tocopherol but not in that of retinyl palmitate in mice.
The American journal of clinical nutrition.
2009 Jan; 89(1):177-84. doi:
10.3945/ajcn.2008.26559. [PMID: 19056557] - Marcos Roberto De Oliveira, José Cláudio Fonseca Moreira. Impaired redox state and respiratory chain enzyme activities in the cerebellum of vitamin A-treated rats.
Toxicology.
2008 Nov; 253(1-3):125-30. doi:
10.1016/j.tox.2008.09.003. [PMID: 18832005] - Limin Liu, Xiao-Han Tang, Lorraine J Gudas. Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet.
Biochemical pharmacology.
2008 Jun; 75(12):2316-24. doi:
10.1016/j.bcp.2008.03.012. [PMID: 18455147] - Mariacristina Guidetti, Annalisa Sforzini, Germana Bersani, Catia Corsini, Gabriele Grossi, Carola Zolezzi, Cinzia Fasano, Loris Pironi. Vitamin A and vitamin E isoforms stability and peroxidation potential of all-in-one admixtures for parenteral nutrition.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
2008 May; 78(3):156-66. doi:
10.1024/0300-9831.78.3.156. [PMID: 19003738] - Lawrence W Castellani, Cara N Nguyen, Sarada Charugundla, Michael M Weinstein, Chau X Doan, William S Blaner, Nuttaporn Wongsiriroj, Aldons J Lusis. Apolipoprotein AII is a regulator of very low density lipoprotein metabolism and insulin resistance.
The Journal of biological chemistry.
2008 Apr; 283(17):11633-44. doi:
10.1074/jbc.m708995200. [PMID: 18160395] - Y Jiménez-Gómez, F Pérez-Jiménez, C Marín, P Gómez, R Moreno, J Delgado, P Pérez-Martínez, M J Gómez, J López-Miranda. The -250G/A polymorphism in the hepatic lipase gene promoter influences the postprandial lipemic response in healthy men.
Nutrition, metabolism, and cardiovascular diseases : NMCD.
2008 Mar; 18(3):173-81. doi:
10.1016/j.numecd.2006.11.002. [PMID: 17399967] - Katja Kongsbak, Shakuntala H Thilsted, Mohammed A Wahed. Effect of consumption of the nutrient-dense, freshwater small fish Amblypharyngodon mola on biochemical indicators of vitamin A status in Bangladeshi children: a randomised, controlled study of efficacy.
The British journal of nutrition.
2008 Mar; 99(3):581-97. doi:
10.1017/s000711450781912x. [PMID: 17925053] - Carmen Herrero-Barbudo, Fernando Granado-Lorencio, Begoña Olmedilla-Alonso. Suitability of 3-point versus 7-point postprandial retinyl palmitate AUC in human bioavailability studies.
European journal of nutrition.
2008 Feb; 47(1):55-8. doi:
10.1007/s00394-008-0695-x. [PMID: 18227988] - Kevin M Kransler, David A Tonucci, Barbara P McGarrigle, Joseph L Napoli, James R Olson. Gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters retinoid homeostasis in maternal and perinatal tissues of the Holtzman rat.
Toxicology and applied pharmacology.
2007 Oct; 224(1):29-38. doi:
10.1016/j.taap.2007.06.006. [PMID: 17655899] - Kari Mette Murvoll, Janneche Utne Skaare, Henrik Jensen, Bjorn Munro Jenssen. Associations between persistent organic pollutants and vitamin status in Brünnich's guillemot and common eider hatchlings.
The Science of the total environment.
2007 Aug; 381(1-3):134-45. doi:
10.1016/j.scitotenv.2007.03.037. [PMID: 17467774] - Roberto Dimenstein, Raquel Maria da Silva Lourenço, Karla Danielly da Silva Ribeiro. [Impact on colostrum retinol levels of immediate postpartum supplementation with retinyl palmitate].
Revista panamericana de salud publica = Pan American journal of public health.
2007 Jul; 22(1):51-4. doi:
10.1590/s1020-49892007000600007. [PMID: 17931488] - Ibrahim Aladag, Mehmet Guven, Ahmet Eyibilen, Semsettin Sahin, Dogan Köseoglu. Efficacy of vitamin A in experimentally induced acute otitis media.
International journal of pediatric otorhinolaryngology.
2007 Apr; 71(4):623-8. doi:
10.1016/j.ijporl.2006.12.019. [PMID: 17303254] - Shanmugam M Jeyakumar, Ayyalasomayajula Vajreswari, Nappan V Giridharan. Impact of vitamin A on high-density lipoprotein-cholesterol and scavenger receptor class BI in the obese rat.
Obesity (Silver Spring, Md.).
2007 Feb; 15(2):322-9. doi:
10.1038/oby.2007.534. [PMID: 17299104] - Christopher J Cifelli, A Catharine Ross. Chronic vitamin A status and acute repletion with retinyl palmitate are determinants of the distribution and catabolism of all-trans-retinoic acid in rats.
The Journal of nutrition.
2007 Jan; 137(1):63-70. doi:
10.1093/jn/137.1.63. [PMID: 17182802] - A Catharine Ross, Namasivayam Ambalavanan, Reza Zolfaghari, Nan-qian Li. Vitamin A combined with retinoic acid increases retinol uptake and lung retinyl ester formation in a synergistic manner in neonatal rats.
Journal of lipid research.
2006 Aug; 47(8):1844-51. doi:
10.1194/jlr.m600061-jlr200. [PMID: 16685080] - Hugh Simon Lam, Chung Mo Chow, Wing Tat Poon, Chi Kong Lai, Kwan Chee Allen Chan, Wai Lan Yeung, Joannie Hui, Albert Yan Wo Chan, Pak Cheung Ng. Risk of vitamin A toxicity from candy-like chewable vitamin supplements for children.
Pediatrics.
2006 Aug; 118(2):820-4. doi:
10.1542/peds.2006-0167. [PMID: 16882846] - M Raju, R Lakshminarayana, T P Krishnakantha, V Baskaran. Micellar oleic and eicosapentaenoic acid but not linoleic acid influences the beta-carotene uptake and its cleavage into retinol in rats.
Molecular and cellular biochemistry.
2006 Aug; 288(1-2):7-15. doi:
10.1007/s11010-005-9091-5. [PMID: 16845492] - Qingsu Xia, Jun J Yin, Wayne G Wamer, Shu-Hui Cherng, Mary D Boudreau, Paul C Howard, Hongtao Yu, Peter P Fu. Photoirradiation of retinyl palmitate in ethanol with ultraviolet light--formation of photodecomposition products, reactive oxygen species, and lipid peroxides.
International journal of environmental research and public health.
2006 Jun; 3(2):185-90. doi:
10.3390/ijerph2006030021. [PMID: 16823091] - G J Nohynek, W J A Meuling, W H J Vaes, R S Lawrence, S Shapiro, S Schulte, W Steiling, J Bausch, E Gerber, H Sasa, H Nau. Repeated topical treatment, in contrast to single oral doses, with Vitamin A-containing preparations does not affect plasma concentrations of retinol, retinyl esters or retinoic acids in female subjects of child-bearing age.
Toxicology letters.
2006 May; 163(1):65-76. doi:
10.1016/j.toxlet.2005.09.029. [PMID: 16243460] - Qingsu Xia, Jun Jie Yin, Shu-Hui Cherng, Wayne G Wamer, Mary Boudreau, Paul C Howard, Peter P Fu. UVA photoirradiation of retinyl palmitate--formation of singlet oxygen and superoxide, and their role in induction of lipid peroxidation.
Toxicology letters.
2006 May; 163(1):30-43. doi:
10.1016/j.toxlet.2005.09.010. [PMID: 16384671] - K Al Majali, M B Cooper, B Staels, G Luc, M-R Taskinen, D J Betteridge. The effect of sensitisation to insulin with pioglitazone on fasting and postprandial lipid metabolism, lipoprotein modification by lipases, and lipid transfer activities in type 2 diabetic patients.
Diabetologia.
2006 Mar; 49(3):527-37. doi:
10.1007/s00125-005-0092-4. [PMID: 16429317] - Anargyros N Moulas, Irini C Gerogianni, Dimitrios Papadopoulos, Konstantinos I Gourgoulianis. Serum retinoic acid, retinol and retinyl palmitate levels in patients with lung cancer.
Respirology (Carlton, Vic.).
2006 Mar; 11(2):169-74. doi:
10.1111/j.1440-1843.2006.00833.x. [PMID: 16548902] - Louise Champoux, Jean Rodrigue, Suzanne Trudeau, Monique H Boily, Philip A Spear, Alice Hontela. Contamination and biomarkers in the great blue heron, an indicator of the state of the st. Lawrence river.
Ecotoxicology (London, England).
2006 Feb; 15(1):83-96. doi:
10.1007/s10646-005-0043-3. [PMID: 16400530] - Emmanuelle Reboul, Amélie Berton, Myriam Moussa, Corinne Kreuzer, Isabelle Crenon, Patrick Borel. Pancreatic lipase and pancreatic lipase-related protein 2, but not pancreatic lipase-related protein 1, hydrolyze retinyl palmitate in physiological conditions.
Biochimica et biophysica acta.
2006 Jan; 1761(1):4-10. doi:
10.1016/j.bbalip.2005.12.013. [PMID: 16497549] - Kari Mette Murvoll, Janneche Utne Skaare, Endre Anderssen, Bjorn Munro Jenssen. Exposure and effects of persistent organic pollutants in European shag (Phalacrocorax aristotelis) hatchlings from the coast of Norway.
Environmental toxicology and chemistry.
2006 Jan; 25(1):190-8. doi:
10.1897/04-333r.1. [PMID: 16494241] - Sherry A Tanumihardjo, Julie A Howe. Twice the amount of alpha-carotene isolated from carrots is as effective as beta-carotene in maintaining the vitamin A status of Mongolian gerbils.
The Journal of nutrition.
2005 Nov; 135(11):2622-6. doi:
10.1093/jn/135.11.2622. [PMID: 16251621] - Andrew P Feranchak, Jane Gralla, Robert King, Rebecca O Ramirez, Mary Corkill, Michael R Narkewicz, Ronald J Sokol. Comparison of indices of vitamin A status in children with chronic liver disease.
Hepatology (Baltimore, Md.).
2005 Oct; 42(4):782-92. doi:
10.1002/hep.20864. [PMID: 16175620]