Benzophenone (BioDeep_00000001854)

 

Secondary id: BioDeep_00000870837, BioDeep_00001867618

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


Benzophenone (diphenyl-ketone)

化学式: C13H10O (182.0732)
中文名称: 二苯甲酮
谱图信息: 最多检出来源 Homo sapiens(otcml) 9.61%

分子结构信息

SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC=C2
InChI: InChI=1S/C13H10O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

描述信息

Benzophenone is the organic compound with the formula (C6H5)2CO, generally abbreviated Ph2CO. It is a widely used building block in organic chemistry, being the parent diarylketone. Benzophenone is found in fruits. Benzophenone is present in grapes and it is also used as a flavouring agent. Benzophenone is a common photosensitizer in photochemistry. It crosses from the S1 state into the triplet state with nearly 100\\\\% yield. The resulting diradical will abstract a hydrogen atom from a suitable hydrogen donor to form a ketyl radical.
D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents
CONFIDENCE standard compound; INTERNAL_ID 15
D003879 - Dermatologic Agents
Benzophenone is an endogenous metabolite.
Benzophenone is an endogenous metabolite.

同义名列表

33 个代谢物同义名

Benzophenone (diphenyl-ketone); METHANONE, diphenyl- (9ci); alpha -Oxodiphenylmethane; alpha-Oxodiphenylmethane; Diphenylmethanone, 9ci; Α-oxodiphenylmethane; a-Oxodiphenylmethane; Di(phenyl)methanone; Diphenyl-methanone; BENZOPHENONE (8ci); Diphenyl-methanon; DIPHENYLMETHANONE; alpha -Oxoditane; Ketone, diphenyl; alpha-Oxoditane; Benzoyl-benzene; Diphenyl ketone; Diphenylketone; Benzoylbenzene; ADK stab 1413; Benzopheneone; Phenyl ketone; Adjutan 6016; BENZOPHENONE; Kayacure BP; Α-oxoditane; a-Oxoditane; FEMA 2134; PH2CO; 1DZP; BZQ; Benzophenone; Benzophenone



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

26 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ABCB1, ALB, ANG, CASP3, CAT, ESR1, FNTA, PTGS2, TUBB4B, VEGFA, YBX1
Peripheral membrane protein 4 ACHE, CYP1B1, ESR1, PTGS2
Endoplasmic reticulum membrane 2 CYP1B1, PTGS2
Nucleus 8 ACHE, ALB, ANG, CASP3, ESR1, TUBB4B, VEGFA, YBX1
cytosol 10 ALB, ANG, CASP3, CAT, ESR1, FNTA, LIPE, PRKCQ, TUBB4B, YBX1
centrosome 1 ALB
nucleoplasm 3 CASP3, ESR1, YBX1
Cell membrane 5 ABCB1, ACHE, ESR1, GPRC5A, LIPE
Cytoplasmic side 1 ESR1
Cytoplasmic granule 1 YBX1
Multi-pass membrane protein 2 ABCB1, GPRC5A
Synapse 2 ACHE, YBX1
cell surface 3 ABCB1, ACHE, VEGFA
glutamatergic synapse 1 CASP3
Golgi apparatus 4 ACHE, ALB, ESR1, VEGFA
growth cone 1 ANG
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 2 ANG, CASP3
Cytoplasm, cytosol 1 LIPE
Lysosome 1 GAA
plasma membrane 8 ABCB1, ACHE, ESR1, FNTA, GAA, GPRC5A, PRKCQ, YBX1
Membrane 8 ABCB1, ACHE, CAT, CYP1B1, ESR1, GAA, LIPE, VEGFA
apical plasma membrane 1 ABCB1
caveola 2 LIPE, PTGS2
extracellular exosome 8 ABCB1, ALB, CAT, GAA, GPRC5A, LYZ, TUBB4B, YBX1
Lysosome membrane 1 GAA
endoplasmic reticulum 4 ALB, PTGS2, VEGFA, YBX1
extracellular space 7 ACHE, ALB, ANG, IGFBP4, LYZ, PTH, VEGFA
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 1 ACHE
adherens junction 1 VEGFA
mitochondrion 2 CAT, CYP1B1
protein-containing complex 4 ALB, CAT, ESR1, PTGS2
intracellular membrane-bounded organelle 5 CAT, CYP1B1, GAA, GPRC5A, YBX1
Microsome membrane 2 CYP1B1, PTGS2
postsynaptic density 1 CASP3
Secreted 6 ACHE, ALB, ANG, GAA, VEGFA, YBX1
extracellular region 11 ACHE, ALB, ANG, CAT, GAA, IGFBP4, LYZ, PTH, TUBB4B, VEGFA, YBX1
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
anchoring junction 1 ALB
transcription regulator complex 1 ESR1
centriolar satellite 1 PRKCQ
Extracellular vesicle 1 TUBB4B
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 ANG
microtubule cytoskeleton 1 TUBB4B
nucleolus 2 ANG, GPRC5A
Cytoplasm, P-body 1 YBX1
P-body 1 YBX1
vesicle 1 GPRC5A
Apical cell membrane 1 ABCB1
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 CAT
microtubule 1 TUBB4B
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
basement membrane 2 ACHE, ANG
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 VEGFA
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 GPRC5A
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 1 ESR1
microtubule associated complex 1 FNTA
mitotic spindle 1 TUBB4B
Chromosome 1 ANG
cytoskeleton 1 TUBB4B
centriole 1 ALB
Nucleus, nucleolus 1 ANG
spindle pole 1 ALB
blood microparticle 1 ALB
Lipid-anchor, GPI-anchor 1 ACHE
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
axonemal microtubule 1 TUBB4B
Cytoplasmic vesicle membrane 1 GPRC5A
tertiary granule membrane 1 GAA
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 2 ANG, YBX1
euchromatin 1 ESR1
side of membrane 1 ACHE
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 3 ALB, IGFBP4, PTGS2
platelet alpha granule lumen 2 ALB, VEGFA
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
endocytic vesicle 1 ANG
azurophil granule membrane 1 GAA
Secreted, extracellular exosome 1 YBX1
azurophil granule lumen 2 LYZ, TUBB4B
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
ribonucleoprotein complex 1 YBX1
[Isoform 1]: Nucleus 1 ESR1
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
external side of apical plasma membrane 1 ABCB1
death-inducing signaling complex 1 CASP3
U12-type spliceosomal complex 1 YBX1
CRD-mediated mRNA stability complex 1 YBX1
histone pre-mRNA 3'end processing complex 1 YBX1
angiogenin-PRI complex 1 ANG
catalase complex 1 CAT
autolysosome lumen 1 GAA
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform H]: Cell membrane 1 ACHE
CAAX-protein geranylgeranyltransferase complex 1 FNTA
protein farnesyltransferase complex 1 FNTA
ciliary transition fiber 1 ALB


文献列表

  • Qi Chen, Qianyu Chen, Guanyong Su, Da Chen, Zhen Ding, Hong Sun. The associations between high-levels of urine benzophenone-type UV filters (BPs) and changes in serum lipid concentrations. Chemosphere. 2023 Oct; 346(?):140545. doi: 10.1016/j.chemosphere.2023.140545. [PMID: 37898463]
  • Weihua Zhang, Baosen Yue, Feng Zhao, Yuan Zhi, Xiayin Wang, Shuai Yang, Dan Sun, Nan Lv, Xiaojing Wu. Investigating the potential anti-inflammatory mechanism of benzophenone compounds from the leaves of Aquilaria sinensis (Lour.) Gilg based on network pharmacology and molecular docking strategies. Toxicology mechanisms and methods. 2023 Jul; ?(?):1-11. doi: 10.1080/15376516.2023.2223291. [PMID: 37434431]
  • Jiayin Long, Qingqing Mao, Yujie Peng, Lei Liu, Yin Hong, Honglin Xiang, Ming Ma, Hui Zou, Junwei Kuang. Three New Benzophenone Derivatives from Selaginella tamariscina. Molecules (Basel, Switzerland). 2023 Jun; 28(12):. doi: 10.3390/molecules28124582. [PMID: 37375139]
  • Ge Zou, Taobo Li, Wencong Yang, Bing Sun, Yan Chen, Bo Wang, Yanghui Ou, Huijuan Yu, Zhigang She. Antioxidative Indenone and Benzophenone Derivatives from the Mangrove-Derived Fungus Cytospora heveae NSHSJ-2. Marine drugs. 2023 Mar; 21(3):. doi: 10.3390/md21030181. [PMID: 36976230]
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