Cinnamyl alcohol (BioDeep_00000018125)

Main id: BioDeep_00000000853

 

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


cinnamyl alcohol, titanium (4+) salt

化学式: C9H10O (134.0732)
中文名称: 反式-肉桂醇, 肉桂醇, 苯乙烯基甲醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C=CCO
InChI: InChI=1S/C9H10O/c10-8-4-7-9-5-2-1-3-6-9/h1-7,10H,8H2

描述信息

Flavouring ingredient. Cinnamyl alcohol is found in many foods, some of which are papaya, kumquat, german camomile, and common mushroom.
Cinnamyl alcohol is found in anise. Cinnamyl alcohol is a flavouring ingredien
Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity[1].
Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity[1].

同义名列表

22 个代谢物同义名

cinnamyl alcohol, titanium (4+) salt; cinnamyl alcohol, (E)-isomer; gamma-Phenylallyl alcohol; 3-phenyl-2-propene-1-ol; 3-phenylprop-2-en-1-ol; 3-PHENYL-2-PROPEN-1-OL; 1-Phenyl-1-propen-3-ol; Cinnamyl alcohol, 8ci; 3-Phenylallyl alcohol; Phenyl-2-propen-1-ol; Phenylallyl alcohol; 3-Phenyl-2-propenol; Phenyl-2-propenol; cinnamic alcohol; Cinnamyl alcohol; Styryl alcohol; Styrylcarbinol; Zimtalcohol; FEMA 2294; Styrone; Cinnamyl alcohol; Styryl carbinol



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

111 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADIG, CASP1, CYP2E1, IL18, NLRP3, NOS3, PPARG, PYCARD, SREBF1
Peripheral membrane protein 3 CYP1B1, CYP2E1, HSD17B6
Endoplasmic reticulum membrane 3 CYP1B1, CYP2E1, SREBF1
Nucleus 7 ADIG, GABPA, NLRP3, NOS3, PPARG, PYCARD, SREBF1
cytosol 10 CASP1, GCLM, HBD, IL18, LIPE, NLRP3, NOS3, PPARG, PYCARD, SREBF1
nucleoplasm 6 GABPA, LGR5, NOS3, PPARG, PYCARD, SREBF1
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 3 CASP1, LGR5, LIPE
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 2 LGR5, SREBF1
Golgi apparatus membrane 3 NLRP3, PYCARD, SREBF1
Golgi apparatus 3 ATRN, LGR5, NOS3
Golgi membrane 5 INS, NLRP3, NOS3, PYCARD, SREBF1
mitochondrial inner membrane 1 CYP2E1
neuronal cell body 1 PYCARD
Cytoplasm, cytosol 3 IL18, LIPE, NLRP3
plasma membrane 4 ATRN, CASP1, LGR5, NOS3
Membrane 5 ADIG, CYP1B1, HBD, LIPE, NLRP3
caveola 2 LIPE, NOS3
extracellular exosome 1 ATRN
Lumenal side 1 HSD17B6
endoplasmic reticulum 4 HSD17B6, NLRP3, PYCARD, SREBF1
extracellular space 5 ATRN, CXCL8, IL18, IL4, INS
perinuclear region of cytoplasm 2 NOS3, PPARG
mitochondrion 3 CYP1B1, NLRP3, PYCARD
protein-containing complex 3 CASP1, PYCARD, SREBF1
intracellular membrane-bounded organelle 4 CYP1B1, CYP2E1, HSD17B6, PPARG
Microsome membrane 3 CYP1B1, CYP2E1, HSD17B6
Single-pass type I membrane protein 1 ATRN
Secreted 6 ADIG, CXCL8, IL18, IL4, INS, NLRP3
extracellular region 7 ADIG, CXCL8, IL18, IL4, INS, NLRP3, PYCARD
Single-pass membrane protein 1 ADIG
[Isoform 2]: Secreted 1 ATRN
nucleolus 2 CASP1, PYCARD
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
Mitochondrion inner membrane 1 CYP2E1
microtubule 2 CASP1, PYCARD
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 2 NLRP3, PYCARD
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 3 CASP1, NLRP3, PYCARD
receptor complex 1 PPARG
chromatin 3 GABPA, PPARG, SREBF1
cytoskeleton 1 NOS3
blood microparticle 1 HBD
[Isoform 3]: Secreted 1 ATRN
nuclear envelope 1 SREBF1
Endomembrane system 1 NLRP3
endosome lumen 1 INS
Lipid droplet 2 ADIG, LIPE
Membrane, caveola 1 LIPE
microtubule organizing center 1 NLRP3
Cytoplasmic vesicle membrane 1 SREBF1
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
trans-Golgi network membrane 1 LGR5
secretory granule lumen 2 INS, PYCARD
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
endocytic vesicle membrane 1 NOS3
transport vesicle 1 INS
azurophil granule lumen 1 PYCARD
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
ER to Golgi transport vesicle membrane 1 SREBF1
AIM2 inflammasome complex 2 CASP1, PYCARD
IkappaB kinase complex 1 PYCARD
canonical inflammasome complex 2 CASP1, PYCARD
[Isoform 1]: Cell membrane 1 ATRN
Cytoplasmic vesicle, COPII-coated vesicle membrane 1 SREBF1
hemoglobin complex 1 HBD
haptoglobin-hemoglobin complex 1 HBD
IPAF inflammasome complex 1 CASP1
NLRP1 inflammasome complex 2 CASP1, PYCARD
protease inhibitor complex 1 CASP1
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane 1 SREBF1
[Processed sterol regulatory element-binding protein 1]: Nucleus 1 SREBF1
[Isoform SREBP-1aDelta]: Nucleus 1 SREBF1
[Isoform SREBP-1cDelta]: Nucleus 1 SREBF1
glutamate-cysteine ligase complex 1 GCLM
NLRP6 inflammasome complex 1 PYCARD


文献列表

  • Yae Rim Choi, Young-Suk Kim, Min Jung Kim. Cinnamyl Alcohol Attenuates Adipogenesis in 3T3-L1 Cells by Arresting the Cell Cycle. International journal of molecular sciences. 2024 Jan; 25(2):. doi: 10.3390/ijms25020693. [PMID: 38255766]
  • Yu Dai, Xuemin Zhang, Yao Xu, Ya Wu, Liqi Yang. The Protective Effects of Cinnamyl Alcohol Against Hepatic Steatosis, Oxidative and Inflammatory Stress in Nonalcoholic Fatty Liver Disease Induced by Childhood Obesity. Immunological investigations. 2023 Nov; ?(?):1-15. doi: 10.1080/08820139.2023.2280248. [PMID: 37962037]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Yueshan Pang, Yali Zheng, Ni Yang, Meng Zan, Lu Zhang, WeiJun Ding. Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis. Lipids in health and disease. 2022 Oct; 21(1):98. doi: 10.1186/s12944-022-01711-0. [PMID: 36209126]
  • Meng Zhang, Menglan Dou, Yingying Xia, Zhan Hu, Beijing Zhang, Yongxia Bai, Jia Xie, Qifeng Liu, Changping Xie, Dadong Lu, Shuai Hou, Jianguo He, Jun Tao, Ranfeng Sun. Photostable 1-Trifluoromethyl Cinnamyl Alcohol Derivatives Designed as Potential Fungicides and Bactericides. Journal of agricultural and food chemistry. 2021 May; 69(19):5435-5445. doi: 10.1021/acs.jafc.1c00272. [PMID: 33945271]
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  • Chen Zhang, Qian Xu, Hongliang Hou, Jiawei Wu, Zhaojuan Zheng, Jia Ouyang. Efficient biosynthesis of cinnamyl alcohol by engineered Escherichia coli overexpressing carboxylic acid reductase in a biphasic system. Microbial cell factories. 2020 Aug; 19(1):163. doi: 10.1186/s12934-020-01419-9. [PMID: 32787860]
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  • Wei Chen, Nathan VanOpdorp, Dennis Fitzl, Jagdish Tewari, Peter Friedemann, Tom Greene, Steve Thompson, Siva Kumpatla, Peizhong Zheng. Transposon insertion in a cinnamyl alcohol dehydrogenase gene is responsible for a brown midrib1 mutation in maize. Plant molecular biology. 2012 Oct; 80(3):289-97. doi: 10.1007/s11103-012-9948-4. [PMID: 22847075]
  • Xing Li, Dongming Ma, Jianlin Chen, Gaobin Pu, Yunpeng Ji, Caiyan Lei, Zhigao Du, Benye Liu, Hechun Ye, Hong Wang. Biochemical characterization and identification of a cinnamyl alcohol dehydrogenase from Artemisia annua. Plant science : an international journal of experimental plant biology. 2012 Sep; 193-194(?):85-95. doi: 10.1016/j.plantsci.2012.05.011. [PMID: 22794921]
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