2,4,5-Trichlorophenoxyacetic acid (BioDeep_00000001758)

 

Secondary id: BioDeep_00001867953

human metabolite blood metabolite Industrial Pollutants


代谢物信息卡片


2-(2,4,5-trichlorophenoxy)acetic acid

化学式: C8H5Cl3O3 (253.9304)
中文名称: 2,4,5-涕酸标准溶液, 2,4,5-三氯苯氧乙酸, 2,4,5-三氯苯氧基乙酸
谱图信息: 最多检出来源 Homo sapiens(lipidsearch) 39.78%

分子结构信息

SMILES: C1=C(C(=CC(=C1Cl)Cl)Cl)OCC(=O)O
InChI: InChI=1S/C8H5Cl3O3/c9-4-1-6(11)7(2-5(4)10)14-3-8(12)13/h1-2H,3H2,(H,12,13)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 325; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5072; ORIGINAL_PRECURSOR_SCAN_NO 5067
CONFIDENCE standard compound; INTERNAL_ID 325; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5010; ORIGINAL_PRECURSOR_SCAN_NO 5009
CONFIDENCE standard compound; INTERNAL_ID 325; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4998; ORIGINAL_PRECURSOR_SCAN_NO 4994
CONFIDENCE standard compound; INTERNAL_ID 325; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4994; ORIGINAL_PRECURSOR_SCAN_NO 4991
CONFIDENCE standard compound; INTERNAL_ID 325; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4980; ORIGINAL_PRECURSOR_SCAN_NO 4977
CONFIDENCE standard compound; INTERNAL_ID 325; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4981; ORIGINAL_PRECURSOR_SCAN_NO 4979
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals
KEIO_ID T113

同义名列表

12 个代谢物同义名

2-(2,4,5-trichlorophenoxy)acetic acid; (2,4,5-Trichlorphenoxy)essigsaeure; 2,4,5-trichlorophenoxyacetic acid; 2,4,5-Trichlorphenoxyessigsaeure; 2,4,5-Trichlorophenoxyacetate; Esteron 245; Trioxone; 2,4,5-T; fortex; 2,4,5-T; 2,4,5-Trichlorophenoxyacetic acid; 2,4,5-Trichlorophenoxyacetic acid



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ALB, BIRC7, CAT, CHAT, DNM2, FTO, GAPDH, GYG1, HPGDS, PPM1G, TYR
Peripheral membrane protein 3 CRAT, DNM2, MBP
Nucleus 9 ALB, BIRC7, BRD3, CHAT, FTO, GAPDH, GYG1, MBP, PPM1G
cytosol 11 ALB, BIRC7, CAT, CHAT, CRAT, DNM2, FTO, GAPDH, GYG1, HPGDS, MBP
centrosome 3 ALB, BIRC7, DNM2
nucleoplasm 5 ATP2B1, BIRC7, FTO, HPGDS, PPM1G
Cell membrane 2 ABCB5, ATP2B1
Lipid-anchor 1 PPM1G
Cytoplasmic side 1 MBP
Multi-pass membrane protein 3 ABCB5, ABCC3, ATP2B1
Synapse 4 ATP2B1, CHAT, DNM2, MBP
cell junction 1 DNM2
cell surface 1 MBP
glutamatergic synapse 1 ATP2B1
Golgi apparatus 3 ALB, BIRC7, DNM2
Golgi membrane 1 DNM2
mitochondrial inner membrane 1 CRAT
neuronal cell body 1 MBP
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 GAPDH
Lysosome 1 TYR
Presynapse 1 DNM2
endosome 1 DNM2
plasma membrane 7 ABCB5, ABCC3, ATP2B1, DNM2, FTO, GAPDH, MBP
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ABCB5, ABCC3, ATP2B1, CAT, GAPDH, GYG1, PPM1G
basolateral plasma membrane 2 ABCC3, ATP2B1
extracellular exosome 7 ALB, ATP2B1, CAT, DNM2, GAPDH, MBP, SPINK1
endoplasmic reticulum 2 ALB, CRAT
extracellular space 1 ALB
lysosomal lumen 1 GYG1
perinuclear region of cytoplasm 3 GAPDH, INF2, TYR
mitochondrion 2 CAT, CRAT
protein-containing complex 3 ALB, CAT, MBP
intracellular membrane-bounded organelle 6 ATP2B1, CAT, FTO, GAPDH, HPGDS, TYR
postsynaptic density 1 DNM2
Single-pass type I membrane protein 1 TYR
Secreted 2 ALB, SPINK1
extracellular region 4 ALB, CAT, GYG1, MBP
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 DNM2
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 GAPDH
microtubule cytoskeleton 1 GAPDH
Melanosome membrane 1 TYR
midbody 1 DNM2
Membrane, clathrin-coated pit 1 DNM2
clathrin-coated pit 1 DNM2
Golgi-associated vesicle 1 TYR
recycling endosome 1 DNM2
vesicle 1 GAPDH
postsynaptic membrane 1 DNM2
Cytoplasm, perinuclear region 2 GAPDH, INF2
Mitochondrion inner membrane 1 CRAT
Matrix side 1 CRAT
Cytoplasm, cytoskeleton 2 DNM2, GAPDH
focal adhesion 2 CAT, DNM2
microtubule 1 DNM2
Peroxisome 2 CAT, CRAT
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, CRAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 MBP
lateral plasma membrane 1 ATP2B1
nuclear speck 1 FTO
neuron projection 2 CHAT, DNM2
ciliary basal body 1 ALB
chromatin 1 BRD3
Cytoplasmic vesicle, phagosome membrane 1 DNM2
Cell projection, phagocytic cup 1 DNM2
cell projection 1 ATP2B1
phagocytic cup 1 DNM2
phagocytic vesicle membrane 1 DNM2
cell periphery 1 MBP
Chromosome 1 BRD3
cytoskeleton 1 GAPDH
Cell projection, podosome 1 DNM2
podosome 1 DNM2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 DNM2
[Isoform 3]: Nucleus 1 MBP
centriole 2 ALB, DNM2
[Isoform 1]: Mitochondrion 1 CRAT
spindle pole 1 ALB
actin filament 1 INF2
blood microparticle 1 ALB
Basolateral cell membrane 2 ABCC3, ATP2B1
Lipid droplet 1 GAPDH
Melanosome 1 TYR
Nucleus speckle 1 FTO
Presynaptic cell membrane 1 ATP2B1
myelin sheath 1 MBP
basal plasma membrane 1 ABCC3
clathrin-coated vesicle 1 DNM2
ficolin-1-rich granule lumen 3 CAT, GYG1, MBP
secretory granule lumen 2 CAT, GYG1
endoplasmic reticulum lumen 1 ALB
platelet alpha granule lumen 1 ALB
endocytic vesicle membrane 1 DNM2
Cytoplasmic vesicle, clathrin-coated vesicle 1 DNM2
transport vesicle 1 MBP
immunological synapse 1 ATP2B1
ribonucleoprotein complex 1 GAPDH
uropod 1 DNM2
Synapse, synaptosome 1 DNM2
Basal cell membrane 1 ABCC3
Cell projection, uropodium 1 DNM2
GAIT complex 1 GAPDH
compact myelin 1 MBP
internode region of axon 1 MBP
catalase complex 1 CAT
photoreceptor ribbon synapse 1 ATP2B1
[Bone marrow proteoglycan]: Secreted 1 MBP
[Isoform 2]: Peroxisome 1 CRAT
ciliary transition fiber 1 ALB
Myelin membrane 1 MBP


文献列表

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  • Shohei Hayashi, Tomoki Sano, Kousuke Suyama, Kazuhito Itoh. 2,4-Dichlorophenoxyacetic acid (2,4-D)- and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T)-degrading gene cluster in the soybean root-nodulating bacterium Bradyrhizobium elkanii USDA94. Microbiological research. 2016 Jul; 188-189(?):62-71. doi: 10.1016/j.micres.2016.04.014. [PMID: 27296963]
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  • Ryan C Lewis, David E Cantonwine, Liza V Anzalota Del Toro, Antonia M Calafat, Liza Valentin-Blasini, Mark D Davis, Samuel E Baker, Akram N Alshawabkeh, José F Cordero, John D Meeker. Urinary biomarkers of exposure to insecticides, herbicides, and one insect repellent among pregnant women in Puerto Rico. Environmental health : a global access science source. 2014 Nov; 13(?):97. doi: 10.1186/1476-069x-13-97. [PMID: 25409771]
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