3,3',4',5-Tetrachlorosalicylanilide (BioDeep_00000174024)
human metabolite blood metabolite
代谢物信息卡片
化学式: C13H7Cl4NO2 (348.9231)
中文名称: 3,3,4,5-四氯水杨酰苯胺
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: C1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)Cl)Cl)O)Cl)Cl
InChI: InChI=1S/C13H7Cl4NO2/c14-6-3-8(12(19)11(17)4-6)13(20)18-7-1-2-9(15)10(16)5-7/h1-5,19H,(H,18,20)
描述信息
D004791 - Enzyme Inhibitors
同义名列表
28 个代谢物同义名
3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxybenzene-1-carboximidic acid; 3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxybenzenecarboximidic acid; 3,5-Dichloro-N-(3,4-dichloro-phenyl)-2-hydroxy-benzamide; 3,5-Dichlorosalicylic acid 3,4-dichloroanilide; 3,5-Dichlorosalicylate 3,4-dichloroanilide; 3,5-Dichlorosalicyl 3,4-dichloroanilide; 3,3,4,5-Tetrachlorosalicylanilide; 3,5,3,4-Tetrachlorosalicylanilide; TCSA; 3,3',4',5-tetrachlorosalicylanilide; 3,3',4',5-TETRACHLOROSALICYLANILIDE [HSDB]; 3,3',4',5-TETRACHLOROSALICYLANILIDE [MI]; 3,3'',4'',5-TETRACHLOROSALICYLANILIDE; 3,3'''',4'''',5-tetrachlorosalicylanilide; 3,4-Dichlorfenylamid kyseliny 3,5-dichlorsalicylove; 3,4-Dichlorfenylamid kyseliny 3,5-dichlorsalicylove [Czech]; 3,4-Dichlorfenylamide kyseliny 3,5-dichlorsalicyclove; 3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxy-benzamide; 3,5-Dichloro-N-(3,4-dichlorophenyl)-2-hydroxybenzamide; 3,5-Dichlorosalicyl-3,4-dichloroanilide; 3,5,3',4'-Tetrachlorosalicylanilide; Benzamide, 3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxy-; Benzamide,3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxy-; Impregon; Oprea1_173387; SALICYLANILIDE, 3,3',4',5-TETRACHLORO-; SJQBHPJLLIJASD-UHFFFAOYSA-; Tox21_302073
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:188648
- PubChem: 14385
- HMDB: HMDB0246012
- ChEMBL: CHEMBL291338
- chemspider: 13743
- CAS: 1154-59-2
- MeSH: 3,3',4',5-tetrachlorosalicylanilide
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Plant physiology and biochemistry : PPB.
2024 Mar; 208(?):108449. doi:
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Journal of medicinal chemistry.
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Bioorganic & medicinal chemistry.
2010 Dec; 18(24):8512-29. doi:
10.1016/j.bmc.2010.10.036. [PMID: 21075637] - Kamalan Jeevaratnam, Vishna Devi Nadarajah, John Paul Judson, Sivalingam Nalliah, Mohd Farouk Abdullah. Periodic assessment of plasma sFlt-1 and PlGF concentrations and its association with placental morphometry in gestational hypertension (GH) - a prospective follow-up study.
BMC pregnancy and childbirth.
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PloS one.
2008 Jun; 3(6):e2491. doi:
10.1371/journal.pone.0002491. [PMID: 18560512] - D S Intrigliolo, J R Castel. Crop load affects maximum daily trunk shrinkage of plum trees.
Tree physiology.
2007 Jan; 27(1):89-96. doi:
10.1093/treephys/27.1.89. [PMID: 17169910] - Wayne G Reeve, Lambert Bräu, Joanne Castelli, Giovanni Garau, Christian Sohlenkamp, Otto Geiger, Michael J Dilworth, Andrew R Glenn, John G Howieson, Ravi P Tiwari. The Sinorhizobium medicae WSM419 lpiA gene is transcriptionally activated by FsrR and required to enhance survival in lethal acid conditions.
Microbiology (Reading, England).
2006 Oct; 152(Pt 10):3049-3059. doi:
10.1099/mic.0.28764-0. [PMID: 17005985] - H Hashizume, Y Tokura, T Oku, Y Iwamoto, M Takigawa. Photodynamic DNA-breaking activity of serum from patients with various photosensitivity dermatoses.
Archives of dermatological research.
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The American journal of physiology.
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10.1152/ajprenal.1988.255.5.f885. [PMID: 2461097] - S Wakabayashi, T Ogurusu, M Shigekawa. Mechanism for 3,3',4',5-tetrachlorosalicylanilide-induced activation of sarcoplasmic reticulum ATPase.
The Journal of biological chemistry.
1988 Oct; 263(30):15304-12. doi:
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1984 Jan; 19(1):69-73. doi:
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Photochemistry and photobiology.
1982 May; 35(5):643-7. doi:
10.1111/j.1751-1097.1982.tb02623.x. [PMID: 7089070] - A Heinz, G Sachs, J A Schafer. Evidence for activation of an active electrogenic proton pump in Ehrlich ascites tumor cells during glycolysis.
The Journal of membrane biology.
1981; 61(3):143-53. doi:
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Biochimica et biophysica acta.
1979 Aug; 555(2):337-48. doi:
10.1016/0005-2736(79)90172-x. [PMID: 224927] - R Fänge, M L Johansson-Sjöbeck. The effect of splenectomy on the hematology and on the activity of delta-aminolevulinic acid dehydratase (ALA-D) in hemopoietic tissues of the dogfish, Scyliorhinus canicula (Elasmobranchii).
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