Calcitriol (BioDeep_00000001717)

 

Secondary id: BioDeep_00000789046

human metabolite Endogenous blood metabolite


代谢物信息卡片


(1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol

化学式: C27H44O3 (416.3290274)
中文名称: 钙三醇
谱图信息: 最多检出来源 Homo sapiens(feces) 0.04%

分子结构信息

SMILES: C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)(C)O)CC(O)CC1O
InChI: InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10-,21-11+

描述信息

The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (calcifediol). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.--PubChem [HMDB]
The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (calcifediol). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.--PubChem.
A - Alimentary tract and metabolism > A11 - Vitamins > A11C - Vitamin a and d, incl. combinations of the two > A11CC - Vitamin d and analogues
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents > D002120 - Calcium Channel Agonists
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map
C274 - Antineoplastic Agent > C2122 - Cell Differentiating Agent > C1934 - Differentiation Inducer
D018977 - Micronutrients > D014815 - Vitamins > D004100 - Dihydroxycholecalciferols
D - Dermatologicals > D05 - Antipsoriatics > D05A - Antipsoriatics for topical use
D018977 - Micronutrients > D014815 - Vitamins > D006887 - Hydroxycholecalciferols
D000077264 - Calcium-Regulating Hormones and Agents
D050071 - Bone Density Conservation Agents
D049990 - Membrane Transport Modulators
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

92 个代谢物同义名

(1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol; 5-{2-[1-(5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol; 1a,25-Dihydroxyvitamin D3 / 1a,25-dihydroxycholecalciferol / calcitriol; 1Α,25-dihydroxyvitamin D3 / 1α,25-dihydroxycholecalciferol / calcitriol; (1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; (5Z,7E)-(1S,3R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; (1S,3R,5Z,7E)-9,10-Seco-5,7,10(19)-cholestatriene-1,3,25-triol; (1Α,3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol; (1a,3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; (1S,3R,5Z,7E)-9,10-Secocholesta-5,7,10-triene-1,3,25-triol; (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol; 20 Epi 1alpha,25 dihydroxycholecaliferol; 20-Epi-1alpha,25-dihydroxycholecaliferol; 1 alpha, 25 Dihydroxy 20 epi vitamin D3; 1 alpha, 25-Dihydroxy-20-epi-vitamin D3; Hoffmann la roche brand OF calcitriol; Hoffmann-la roche brand OF calcitriol; 1 alpha,25-Dihydroxycholecalciferol; 1 alpha,25 Dihydroxycholecalciferol; 1alpha,25-Dihydroxycholecalciferol; D3, 1,25-Dihydroxy-20-epi-vitamin; 1,25 Dihydroxy 20 epi vitamin D3; 1,25-Dihydroxy-20-epi-vitamin D3; alpha,25-Dihydroxyvitamin D3, 1; D3, 1 alpha,25-Dihydroxyvitamin; 1-alpha,25-Dihydroxyvitamin D3; 1 alpha,25 Dihydroxyvitamin D3; 1Α,25-dihydroxycholecalciferol; Cryopharma brand OF calcitriol; 1a,25-Dihydroxycholecalciferol; 1-alpha-25-Dihydroxyvitamin D3; 1 alpha,25-Dihydroxyvitamin D3; Alphapharm brand OF calcitriol; 1,25-Dihydroxycholecalciferol; 1alpha,25-Dihydroxyvitamin D3; 1,25 Dihydroxycholecalciferol; Jenapharm brand OF calcitriol; Galderma brand OF calcitriol; RenaCare brand OF calcitriol; 25-Dihydroxycholecalciferol; KyraMed brand OF calcitriol; Calcitriol alphapharm brand; Calcitriol cryopharma brand; 1-a-25-Dihydroxyvitamin D3; Abbott brand OF calcitriol; 1-Α-25-dihydroxyvitamin D3; Medice brand OF calcitriol; Calcitriol jenapharm brand; Calcitriol renacare brand; 1a,25-Dihydroxyvitamin D3; 1Α,25-dihydroxyvitamin D3; Calcitriol galderma brand; Roche brand OF calcitriol; D3, 1,25-Dihydroxyvitamin; Calcitriol kyramed brand; 1,25-Dihydroxyvitamin D3; 1,25 Dihydroxyvitamin D3; Calcitriol abbott brand; Gry brand OF calcitriol; 1,25-Dihydroxyvitamin D; Leo brand OF calcitriol; Calcitriol medice brand; Calcitriol roche brand; Calcitriol gry brand; Calcitriol leo brand; Dihydroxyvitamin D3; KyraMed, calcitriol; 1,25(OH)2-20EPi-D3; Calcitriol kyramed; Calcitriol nefro; 1alpha,25(OH)2D3; Calcitriol-nefro; CalcitriolNefro; 1a,25-(OH)2D3; 1Α,25(OH)2D3; Calcitriolum; 1a,25(OH)2D3; Calcitriol; Ro 21-5535; Osteotriol; Decostriol; Topitriol; Rocaltrol; Bocatriol; 1,25-DHCC; Renatriol; Calcijex; Soltriol; Toptriol; Sitriol; Tirocal; Silkis



数据库引用编号

25 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(12)

BioCyc(0)

PlantCyc(0)

代谢反应

81 个相关的代谢反应过程信息。

Reactome(80)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Junyue Wang, Claire Shuiqing Zhang, Anthony Lin Zhang, Charlie Changli Xue, Chuanjian Lu. Chinese herbal medicine bath therapy for psoriasis vulgaris using topical calcipotriol as the comparator: A systematic review with meta-analysis and association rule analysis. Journal of ethnopharmacology. 2024 Aug; 330(?):118166. doi: 10.1016/j.jep.2024.118166. [PMID: 38621466]
  • Chiu-Li Yeh, Jin-Ming Wu, Kuen-Yuan Chen, Ming-Hsun Wu, Po-Jen Yang, Po-Chu Lee, Po-Da Chen, Ting-Chun Kuo, Sung-Ling Yeh, Ming-Tsan Lin. Calcitriol attenuates poly(I:C)-induced lung injury in obese mice via modulating toll-like receptor 3- and renin-angiotensin system-associated signal pathways. International immunopharmacology. 2024 Jan; 128(?):111522. doi: 10.1016/j.intimp.2024.111522. [PMID: 38246004]
  • Zanxia Cao, Liling Zhao, Mingcui Chen, Zhihong Shi, Lei Liu. Molecular mechanism of calcitriol enhances membrane water permeability. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2024 01; 1869(1):159430. doi: 10.1016/j.bbalip.2023.159430. [PMID: 37979445]
  • Bo Wang, Lei Gu, Jun Liu. Correlation between parathyroid function and serum levels of 1,25(OH)2D3, serum phosphorus, and parathyroid hormone after surgery for papillary thyroid carcinoma. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Dec; 69(14):45-50. doi: 10.14715/cmb/2023.69.14.8. [PMID: 38279486]
  • Rakesh Balachandar, Ankit Viramgami, Dhirendrapratap Singh, P Sivaperumal, Kuldip Upadhyay. Unraveling the interaction between lead and calcium in occupationally exposed males: an exploratory observation study. International archives of occupational and environmental health. 2023 Dec; 96(10):1393-1399. doi: 10.1007/s00420-023-02018-y. [PMID: 37889332]
  • Ruili Dang, Jing Wang, Mimi Tang, Wenxiu Han, Pei Jiang. Vitamin D Receptor Activation Attenuates Olanzapine-Induced Dyslipidemia in Mice Through Alleviating Hepatic Endoplasmic Reticulum Stress. Advanced biology. 2023 Dec; 7(12):e2300228. doi: 10.1002/adbi.202300228. [PMID: 37565702]
  • Sandra Romero-Córdoba, Mayel Chirinos, Nancy Noyola-Martínez, Nayeli Torres-Ramirez, Mitzi García-Olivares, Juan Pablo Aragón-Hernández, Jazmín Ixchel Ramírez-Camacho, Rosa Zúñiga, Fernando Larrea, Ali Halhali, David Barrera. Transcriptional landscape of human trophoblast cells treated with calcitriol and TGF-β1. Molecular and cellular endocrinology. 2023 Oct; ?(?):112088. doi: 10.1016/j.mce.2023.112088. [PMID: 37832930]
  • Bruno Machado Bertassoli, Marília Martins Melo, Natália Melo Ocarino, Isabella Cristina Souza Félix, Fabiana Rocha Araújo, Amanda Maria Sena Reis, Endrigo Gabellini Leonel Alves, Eduardo Juan Gimeno, Adriana Raquel Massone, Rogéria Serakides. Effect of the addition of different concentrations of Solanum glaucophyllum desf. extract on chondrocyte cultures from the growth cartilage of newborn rats. Toxicon : official journal of the International Society on Toxinology. 2023 May; 230(?):107158. doi: 10.1016/j.toxicon.2023.107158. [PMID: 37172829]
  • Maher N Ibrahim, Abeer A Khalifa, Dalia A Hemead, Amira Ebrahim Alsemeh, Marwa A Habib. 1,25-Dihydroxycholecalciferol down-regulates 3-mercaptopyruvate sulfur transferase and caspase-3 in rat model of non-alcoholic fatty liver disease. Journal of molecular histology. 2023 Apr; 54(2):119-134. doi: 10.1007/s10735-023-10118-9. [PMID: 36930413]
  • Yijie Jiang, Jianshu Yang, Ke Du, Kaiming Luo, Xin Yuan, Fei Hua. 1,25-Dihydroxyvitamin D3 alleviates hyperandrogen-induced ferroptosis in KGN cells. Hormones (Athens, Greece). 2023 Mar; ?(?):. doi: 10.1007/s42000-023-00439-5. [PMID: 36884209]
  • Jan Holmback, Anders Carlsson, Puneet Rinwa. Efficacy and Safety of Water-Free Lipid Formulation System Containing Calcipotriol Against Psoriasis Vulgaris. Journal of drugs in dermatology : JDD. 2023 Feb; 22(2):197-202. doi: 10.36849/jdd.7151. [PMID: 36745360]
  • Nai-Rong Kuo, Ming-Chih Hou, Wei-Chi Chu, Ying-Ying Yang, Chia-Chang Huang, Tzu-Hao Li, Tzung-Yan Lee, Chih-Wei Liu, Tsai-Ling Liao, Shie-Liang Hsieh, Han-Chieh Lin. Low lymphocyte-to-monocyte ratio, calcitriol level, and CD206 level predict the development of acute-on-chronic liver failure in patients with cirrhosis with acute decompensation. Journal of the Chinese Medical Association : JCMA. 2023 Jan; ?(?):. doi: 10.1097/jcma.0000000000000867. [PMID: 36727703]
  • Lang Shi, Chao Xiao, Yafei Zhang, Yao Xia, Hongchu Zha, Jiefu Zhu, Zhixia Song. Vitamin D/vitamin D receptor/Atg16L1 axis maintains podocyte autophagy and survival in diabetic kidney disease. Renal failure. 2022 Dec; 44(1):694-705. doi: 10.1080/0886022x.2022.2063744. [PMID: 35469547]
  • Yan-Ting Chen, Li-Mei Lin, Xiao-Dong Wang, Wei-Min Deng, Xiu-Hua Chen. [Effect of Lingnan Chen's acupuncture on postmenopausal osteoporosis and serum GH and IGF-1]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2022 Sep; 42(9):979-84. doi: 10.13703/j.0255-2930.20211010-0001. [PMID: 36075592]
  • Junrong Ren, Qi Zhu, Siyao Wang, Xiaolong Li, Zhen Sun, Nan Li, Jian Feng, Haining Ding, Sitong Dong, Hongmei Wang. Clinical efficacy and safety of using calcipotriol-betamethasone compounding agent for psoriasis treatment: a systematic review and meta-analysis. Archives of dermatological research. 2022 Sep; 314(7):633-641. doi: 10.1007/s00403-021-02272-5. [PMID: 34417633]
  • Chiu-Li Yeh, Jin-Ming Wu, Kuen-Yuan Chen, Ming-Hsun Wu, Po-Jen Yang, Po-Chu Lee, Po-Da Chen, Sung-Ling Yeh, Ming-Tsan Lin. Effects of Different Routes and Forms of Vitamin D Administration on Mesenteric Lymph Node CD4+ T Cell Polarization and Intestinal Injury in Obese Mice Complicated with Polymicrobial Sepsis. Nutrients. 2022 Aug; 14(17):. doi: 10.3390/nu14173557. [PMID: 36079813]
  • Ping-Tsung Chen, Ching-Chuan Hsieh, Miao-Fen Chen. Role of vitamin D3 in tumor aggressiveness and radiation response for hepatocellular carcinoma. Molecular carcinogenesis. 2022 08; 61(8):787-796. doi: 10.1002/mc.23421. [PMID: 35611989]
  • Xuewei Li, Jie Liu, Yingzhe Zhao, Ning Xu, E Lv, Chunzeng Ci, Xiangling Li. 1,25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/lpr mice. BMC nephrology. 2022 07; 23(1):243. doi: 10.1186/s12882-022-02870-z. [PMID: 35804318]
  • Amit Nachankar, Amit Katyal, Naresh Bansal, Alka Bishnoi. Hungry bone syndrome like presentation following single-dose denosumab for hypercalcaemia secondary to sarcoidosis with IgA nephropathy. BMJ case reports. 2022 Jul; 15(7):. doi: 10.1136/bcr-2022-250647. [PMID: 35803612]
  • Emma L Bishop, Nancy H Gudgeon, Gillian M Mackie, Daniel Chauss, Jennie Roberts, Daniel A Tennant, Kendle M Maslowski, Behdad Afzali, Martin Hewison, Sarah Dimeloe. 1,25-Dihydroxyvitamin D3 suppresses CD4+ T-cell effector functionality by inhibition of glycolysis. Immunology. 2022 07; 166(3):299-309. doi: 10.1111/imm.13472. [PMID: 35322416]
  • Ricardo Neto, Luciano Pereira, Juliana Magalhães, Janete Quelhas-Santos, João Frazão. Effect of vitamin D sterols on bone histology in pre-dialysis patients: A prospective controlled study. Clinical nephrology. 2022 Jul; 98(1):17-25. doi: 10.5414/cn110747. [PMID: 35200136]
  • C Jin, C Zhang, X Ni, Z Zhao, L Xu, B Wu, Y Chi, R Jiajue, Y Jiang, O Wang, Mei Li, X Xing, X Meng, W Xia. The efficacy and safety of different doses of calcitriol combined with neutral phosphate in X-linked hypophosphatemia: a prospective study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2022 Jun; 33(6):1385-1395. doi: 10.1007/s00198-021-06221-w. [PMID: 35088103]
  • Marie-Eva Pickering, Damien Bouvier, Antoine Puravet, Martin Soubrier, Vincent Sapin, Charlotte Oris. Hypophosphatemia related to a neuro-endocrine tumor of the pancreas: A case report. Clinical biochemistry. 2022 Jun; 104(?):62-65. doi: 10.1016/j.clinbiochem.2022.03.006. [PMID: 35337828]
  • Youli Wen, Lian Li, Zhiping Deng. Calcitriol supplementation accelerates the recovery of patients with tuberculosis who have vitamin D deficiency: a randomized, single-blind, controlled clinical trial. BMC infectious diseases. 2022 May; 22(1):436. doi: 10.1186/s12879-022-07427-x. [PMID: 35513795]
  • J Vaculik, L Wenchich, M Bobelyak, K Pavelka, J J Stepan. A decrease in serum 1,25(OH)2D after elective hip replacement and during bone healing is associated with changes in serum iron and plasma FGF23. Journal of endocrinological investigation. 2022 May; 45(5):1039-1044. doi: 10.1007/s40618-022-01746-1. [PMID: 35079976]
  • Ruifeng Ding, Yufeng Jiang, Yi Yang, Yong Shi, Yang Ji, Timing Zhen, Zhiliang Fu, Xunxia Bao, Jia Tan, Shuyong Zhang, Jiahui Li, Kaichen Xing, Xinli Zhou, Sibo Zhu. Calcitriol ameliorates renal injury with high-salt diet-induced hypertension by upregulating GLIS2 expression and AMPK/mTOR-regulated autophagy. Gene. 2022 Apr; 820(?):146239. doi: 10.1016/j.gene.2022.146239. [PMID: 35114278]
  • Birthe Bernicke, Nils Engelbogen, Katharina Klein, Jeanette Franzenburg, Christoph Borzikowsky, Christian Peters, Ottmar Janssen, Ralf Junker, Ruben Serrano, Dieter Kabelitz. Analysis of the Seasonal Fluctuation of γδ T Cells and Its Potential Relation with Vitamin D3. Cells. 2022 04; 11(9):. doi: 10.3390/cells11091460. [PMID: 35563767]
  • Ruifeng Ding, Zilong Xiao, Yufeng Jiang, Yi Yang, Yang Ji, Xunxia Bao, Kaichen Xing, Xinli Zhou, Sibo Zhu. Calcitriol ameliorates damage in high-salt diet-induced hypertension: Evidence of communication with the gut-kidney axis. Experimental biology and medicine (Maywood, N.J.). 2022 04; 247(8):624-640. doi: 10.1177/15353702211062507. [PMID: 34894804]
  • Mengjing Wang, Donghai Wen, Weichen Zhang, Weisheng Chen, Ye Tao, Chunyan Fan, Bihong Huang, Jing Chen, Hongying Wang, Minmin Zhang. Effects of Cinacalcet and Parathyroidectomy on Blood Pressure in Maintenance Hemodialysis Patients with Secondary Hyperparathyroidism. Iranian journal of kidney diseases. 2022 03; 16(2):135-146. doi: NULL. [PMID: 35489082]
  • Cora M Best, Robert Sherwood, Janet A Novotny, Sheng Zhang, Eva K Pressman, Kimberly O O'Brien. Vitamin D kinetics in nonpregnant and pregnant women after a single oral dose of trideuterated vitamin D3. The Journal of steroid biochemistry and molecular biology. 2022 02; 216(?):106034. doi: 10.1016/j.jsbmb.2021.106034. [PMID: 34843870]
  • Alireza Mansouri, Rasoul Kowsar, Mostafa Zakariazadeh, Hassan Hakimi, Akio Miyamoto. The impact of calcitriol and estradiol on the SARS-CoV-2 biological activity: a molecular modeling approach. Scientific reports. 2022 01; 12(1):717. doi: 10.1038/s41598-022-04778-y. [PMID: 35027633]
  • John H White. Emerging Roles of Vitamin D-Induced Antimicrobial Peptides in Antiviral Innate Immunity. Nutrients. 2022 Jan; 14(2):. doi: 10.3390/nu14020284. [PMID: 35057465]
  • Yasmine M Elamir, Hajira Amir, Steven Lim, Yesha Patel Rana, Carolina Gonzalez Lopez, Natalia Viera Feliciano, Ali Omar, William Paul Grist, Michael A Via. A randomized pilot study using calcitriol in hospitalized COVID-19 patients. Bone. 2022 01; 154(?):116175. doi: 10.1016/j.bone.2021.116175. [PMID: 34508882]
  • Andrea L Schaffer, David Henry, Helga Zoega, Julian H Elliott, Sallie-Anne Pearson. Changes in dispensing of medicines proposed for re-purposing in the first year of the COVID-19 pandemic in Australia. PloS one. 2022; 17(6):e0269482. doi: 10.1371/journal.pone.0269482. [PMID: 35704621]
  • Masayuki Tanemoto, Yoji Katsuoka. Conversion from intravenous maxacalcitol to oral vitamin D in secondary hyperparathyroidism management. Clinical and experimental nephrology. 2022 01; 26(1):97-98. doi: 10.1007/s10157-021-02138-0. [PMID: 34549338]
  • Joseph A Vaccaro, Ahmad Qasem, Saleh A Naser. Cathelicidin Mediates an Anti-Inflammatory Role of Active Vitamin D (Calcitriol) During M. paratuberculosis Infection. Frontiers in cellular and infection microbiology. 2022; 12(?):875772. doi: 10.3389/fcimb.2022.875772. [PMID: 35444957]
  • Mónica R Meza-Meza, Adolfo I Ruiz-Ballesteros, Ulises de la Cruz-Mosso. Functional effects of vitamin D: From nutrient to immunomodulator. Critical reviews in food science and nutrition. 2022; 62(11):3042-3062. doi: 10.1080/10408398.2020.1862753. [PMID: 33354999]
  • M Miedziaszczyk, I Idasiak-Piechocka, O W Wiśniewski, K Lacka. A systematic review of the pharmacotherapy of secondary hyperparathyroidism (SHPT) in grades 3-5 Chronic Kidney Disease (CKD). European review for medical and pharmacological sciences. 2022 Jan; 26(1):232-239. doi: 10.26355/eurrev_202201_27773. [PMID: 35049000]
  • Mizuki Fukazawa-Shinotsuka, Tomohisa Saito, Masaichi Abe, Satofumi Iida, I-Ting Wang, Kimio Terao, Hsi-Hsien Chen, Ming-Che Liu. Maxacalcitol Pharmacokinetic-Pharmacodynamic Modeling and Simulation for Secondary Hyperparathyroidism in Patients Receiving Maintenance Hemodialysis. Drug research. 2022 Jan; 72(1):23-33. doi: 10.1055/a-1581-7609. [PMID: 34488237]
  • Salah Gariballa, Iltaf Shah, Javed Yasin, Awad Alessa. Vitamin D [25(OH)D] metabolites and epimers in obese subject: Interaction and correlations with adverse metabolic health risk factors. The Journal of steroid biochemistry and molecular biology. 2022 01; 215(?):106023. doi: 10.1016/j.jsbmb.2021.106023. [PMID: 34774725]
  • Elysse A Phillips, Nora Hendricks, Matthew Bucher, Alina Maloyan. Vitamin D Supplementation Improves Mitochondrial Function and Reduces Inflammation in Placentae of Obese Women. Frontiers in endocrinology. 2022; 13(?):893848. doi: 10.3389/fendo.2022.893848. [PMID: 35712242]
  • Qi Li, Hong-Yang Kang, Ling Fan, Ling Zhang, Jie Liu, Chang-Qing Tong, Bin Zhang. [Clinical Study on Calcitriol Combined with Sirolimus in the Treatment of Chronic Primary Immune Thrombocytopenia Patients]. Zhongguo shi yan xue ye xue za zhi. 2021 Dec; 29(6):1911-1916. doi: 10.19746/j.cnki.issn.1009-2137.2021.06.038. [PMID: 34893133]
  • Maria Fusaro, Giuseppe Cianciolo, Giovanni Tripepi, Mario Plebani, Andrea Aghi, Cristina Politi, Martina Zaninotto, Thomas L Nickolas, Serge Ferrari, Markus Ketteler, Gaetano La Manna, Lorenzo Gasperoni, Piergiorgio Messa, Maura Ravera, Maurizio Gallieni, Laura Cosmai, Francesco Locatelli, Giorgio Iervasi, Roberto Vettor, Maria Cristina Mereu, Stefania Sella, Gaetano Arcidiacono, Sandro Giannini. Oral Calcitriol Use, Vertebral Fractures, and Vitamin K in Hemodialysis Patients: A Cross-Sectional Study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021 12; 36(12):2361-2370. doi: 10.1002/jbmr.4440. [PMID: 34622481]
  • Luca Gallelli, Gaia Chiara Mannino, Filippo Luciani, Alessandro de Sire, Elettra Mancuso, Pietro Gangemi, Lucio Cosco, Giuseppe Monea, Carolina Averta, Pasquale Minchella, Manuela Colosimo, Lucia Muraca, Federico Longhini, Antonio Ammendolia, Francesco Andreozzi, Giovambattista De Sarro, G Amp P Working Group, Erika Cione. Vitamin D Serum Levels in Subjects Tested for SARS-CoV-2: What Are the Differences among Acute, Healed, and Negative COVID-19 Patients? A Multicenter Real-Practice Study. Nutrients. 2021 Nov; 13(11):. doi: 10.3390/nu13113932. [PMID: 34836187]
  • Chee Lee Wee, Siti Safiah Mokhtar, Kirnpal Kaur Banga Singh, Aida Hanum Ghulam Rasool. Vitamin D deficiency attenuates endothelial function by reducing antioxidant activity and vascular eNOS expression in the rat microcirculation. Microvascular research. 2021 11; 138(?):104227. doi: 10.1016/j.mvr.2021.104227. [PMID: 34324883]
  • Xia Yang, Jian-Xin Wan, Jing Yuan, Rong Dong, Jing-Jing Da, Zhao-Lin Sun, Yan Zha. Effects of calcitriol on peripheral endothelial progenitor cells and renal renovation in rats with chronic renal failure. The Journal of steroid biochemistry and molecular biology. 2021 11; 214(?):105956. doi: 10.1016/j.jsbmb.2021.105956. [PMID: 34348182]
  • Muhammad Mansyur Romi, Nur Arefian, Wiwit Ananda Wahyu Setyaningsih, Rachma Greta Perdana Putri, Mohammad Juffrie, Dwi Cahyani Ratna Sari. Calcitriol Treatment Attenuates Uric Acid-Induced Kidney Injury via Super Oxide Dismutase-1 (SOD-1) Upregulation and Fibrosis Reduction. Iranian biomedical journal. 2021 11; 25(6):417-25. doi: 10.52547/ibj.25.6.417. [PMID: 34641645]
  • Deniz Genç, Merve Sezer Kürkçü, Burcu Günaydin, Emine Figen Tarhan. 1,25-dihydroxyvitamin D3 regulates t helper and b lymphocyte responses substantially in drug-naive primary Sjögren’s syndrome patients’ mononuclear cells. Turkish journal of medical sciences. 2021 10; 51(5):2467-2476. doi: 10.3906/sag-2103-240. [PMID: 34118806]
  • David C Shonka, Anne K Maxwell, Gina R Petroni, Mark J Jameson. Phase II randomized study of preoperative calcitriol to prevent hypocalcemia following thyroidectomy. Head & neck. 2021 10; 43(10):2935-2945. doi: 10.1002/hed.26775. [PMID: 34076308]
  • Jaruwan Ngamkam, Somratai Vadcharavivad, Nutthada Areepium, Titinun Auamnoy, Kullaya Takkavatakarn, Pisut Katavetin, Khajohn Tiranathanagul, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Paweena Susantitaphong. The impact of CASR A990G polymorphism in response to cinacalcet treatment in hemodialysis patients with secondary hyperparathyroidism. Scientific reports. 2021 09; 11(1):18006. doi: 10.1038/s41598-021-97587-8. [PMID: 34504264]
  • Huilin Song, Xingchen Wang, Siyu Hou, Yuqi Zhang, Xi Luo, Tengfei Li, Shunli Ji. Economical irregular silica as an effective dispersive solid-phase extraction sorbent for the quantification of calcitriol in soft capsules. Journal of pharmaceutical and biomedical analysis. 2021 Sep; 203(?):114227. doi: 10.1016/j.jpba.2021.114227. [PMID: 34198196]
  • Andrea Olmos-Ortiz, Alberto Olivares-Huerta, Janice García-Quiroz, Euclides Avila, Ali Halhali, Braulio Quesada-Reyna, Fernando Larrea, Verónica Zaga-Clavellina, Lorenza Díaz. Cord Serum Calcitriol Inversely Correlates with Maternal Blood Pressure in Urinary Tract Infection-Affected Pregnancies: Sex-Dependent Immune Implications. Nutrients. 2021 Sep; 13(9):. doi: 10.3390/nu13093114. [PMID: 34578991]
  • J Vaculik, L Wenchich, M Bobelyak, K Pavelka, J J Stepan. Decrease in serum calcitriol (but not free 25-hydroxyvitamin D) concentration in hip fracture healing. Journal of endocrinological investigation. 2021 Sep; 44(9):1847-1855. doi: 10.1007/s40618-020-01489-x. [PMID: 33492601]
  • Zi Guo, Liling Zhao, Yanhong Xie, Yun Yan, Zhaohui Mo. Hungry Bone Syndrome Secondary to Subtotal Thyroidectomy in A Patient With Thyrotoxicosis. The American journal of the medical sciences. 2021 09; 362(3):314-320. doi: 10.1016/j.amjms.2021.02.006. [PMID: 33582155]
  • Yidi Wang, Luqin Wan, Zhenzhen Zhang, Jing Li, Mingli Qu, Qingjun Zhou. Topical calcitriol application promotes diabetic corneal wound healing and reinnervation through inhibiting NLRP3 inflammasome activation. Experimental eye research. 2021 08; 209(?):108668. doi: 10.1016/j.exer.2021.108668. [PMID: 34144035]
  • Karen K Winer, Shangyuan Ye, Elise M N Ferré, Monica M Schmitt, Bo Zhang, Gordon B Cutler, Michail S Lionakis. Therapy with PTH 1-34 or calcitriol and calcium in diverse etiologies of hypoparathyroidism over 27 years at a single tertiary care center. Bone. 2021 08; 149(?):115977. doi: 10.1016/j.bone.2021.115977. [PMID: 33932619]
  • María Dolores Arenas Jimenez, Emilio González-Parra, Marta Riera, Abraham Rincón Bello, Ana López-Herradón, Higini Cao, Sara Hurtado, Silvia Collado, Laura Ribera, Francesc Barbosa, Fabiola Dapena, Vicent Torregrosa, José-Jesús Broseta, Carlos Soto Montañez, Juan F Navarro-González, Rosa Ramos, Jordi Bover, Xavier Nogués-Solan, Marta Crespo, Adriana S Dusso, Julio Pascual. Mortality in Hemodialysis Patients with COVID-19, the Effect of Paricalcitol or Calcimimetics. Nutrients. 2021 Jul; 13(8):. doi: 10.3390/nu13082559. [PMID: 34444716]
  • Aliah R Alshanwani, Azza M Mohamed, Laila M Faddah, Sameerah Shaheen, Maha M Arafah, Hanan Hagar, Ahlam M Alhusaini, Fatima M B Alharbi, Alaa AlHarthii, Amira M Badr. Cyanocobalamin and/or calcitriol mitigate renal damage-mediated by tamoxifen in rats: Implication of caspase-3/NF-κB signaling pathways. Life sciences. 2021 Jul; 277(?):119512. doi: 10.1016/j.lfs.2021.119512. [PMID: 33862116]
  • Jianping Mao, Mengjing Wang, Li Ni, Wen Gong, Xinxin Jiang, Qian Zhang, Minmin Zhang, Donghai Wen, Jing Chen. Local NF-κB Activation Promotes Parathyroid Hormone Synthesis and Secretion in Uremic Patients. Endocrinology. 2021 07; 162(7):. doi: 10.1210/endocr/bqab084. [PMID: 33912936]
  • Rocío Fuente, Nicole Gehring, Carla Bettoni, Helena Gil-Peña, Laura Alonso-Durán, Bernhard Michalke, Fernando Santos, Carsten A Wagner, Isabel Rubio-Aliaga. Systemic Jak1 activation causes extrarenal calcitriol production and skeletal alterations provoking stunted growth. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 07; 35(7):e21721. doi: 10.1096/fj.202100587r. [PMID: 34118090]
  • Adela Arapović, Katarina Vukojević, Merica Glavina Durdov, Benjamin Benzon, Ivana Šolić, Anita Racetin, Marija Jurić, Tanja Čujić, Ivona Kosović, Mirela Lozić, Dijana Borić Škaro, Dragan Ljutić, Mirna Saraga-Babić, Ana Simičić Majce, Marijan Saraga, Natalija Filipović. Expression of renal vitamin D receptors and metabolizing enzymes in IgA nephropathy. Acta histochemica. 2021 Jul; 123(5):151740. doi: 10.1016/j.acthis.2021.151740. [PMID: 34111685]
  • A Abdollahi, A Akhlaghi, M J Zamiri, S Kargar, Z Ansari Pirsaraei. Reproductive performance, expression of TRAP6 and TGF-β4 genes in utero-vaginal junction mucosa, and indicators of liver function in female Chukar partridge (Alectoris chukar) breeders fed with fish oil and calcitriol during the egg-laying period. Theriogenology. 2021 Jul; 168(?):50-58. doi: 10.1016/j.theriogenology.2021.03.018. [PMID: 33848970]
  • Julia Kotwan, Julia Kühn, Anja C Baur, Gabriele I Stangl. Oral Intake of Lumisterol Affects the Metabolism of Vitamin D. Molecular nutrition & food research. 2021 07; 65(14):e2001165. doi: 10.1002/mnfr.202001165. [PMID: 34061442]
  • İlknur Bingül, A. Fatih Aydın, Canan Küçükgergin, Işın Doğan-Ekici, Semra Doğru-Abbasoğlu, Müjdat Uysal. The effect of 1,25-dihydroxyvitamin D3 on liver damage, oxidative stress, and advanced glycation end products in experimental nonalcoholic- and alcoholic- fatty liver disease. Turkish journal of medical sciences. 2021 06; 51(3):1500-1511. doi: 10.3906/sag-2007-289. [PMID: 33421970]
  • Yubing Ji, Chunyang Kang, Jiajun Chen, Lei Zhang. Identification of p.Arg205Cys in CASR in an autosomal dominant hypocalcaemia type 1 pedigree: A case report. Medicine. 2021 Jun; 100(25):e26443. doi: 10.1097/md.0000000000026443. [PMID: 34160437]
  • Soma Saha, Vishnubhatla Sreenivas, Ravinder Goswami. Alfacalcidol vs Calcitriol in the Management of Patient With Hypoparathyroidism: A Randomized Controlled Trial. The Journal of clinical endocrinology and metabolism. 2021 06; 106(7):2092-2102. doi: 10.1210/clinem/dgab114. [PMID: 33616655]
  • Hasan Haci Yeter, Berfu Korucu, Elif Burcu Bali, Ulver Derici. Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2021 Jun; 91(3-4):335-342. doi: 10.1024/0300-9831/a000641. [PMID: 32065560]
  • Sofia Ish-Shalom, Yoseph Caraco, Nariman Saba Khazen, Michal Gershinsky, Auryan Szalat, Phillip Schwartz, Ehud Arbit, Hillel Galitzer, Jonathan Cy Tang, Gregory Burshtein, Ariel Rothner, Arthur Raskin, Miriam Blum, William D Fraser. Safety and Efficacy of Oral Human Parathyroid Hormone (1-34) in Hypoparathyroidism: An Open-Label Study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021 06; 36(6):1060-1068. doi: 10.1002/jbmr.4274. [PMID: 33666947]
  • Leila Doryanizadeh, Bahar Morshed-Behbahani, Mohammad Ebrahim Parsanezhad, Mohammad Hossein Dabbaghmanesh, Azam Jokar. Calcitriol Effect on Outcomes of in Vitro Fertilization in Infertile Women with Vitamin D Deficiency: A Double-Blind Randomized Clinical Trial. Zeitschrift fur Geburtshilfe und Neonatologie. 2021 Jun; 225(3):226-231. doi: 10.1055/a-1206-1064. [PMID: 32927487]
  • Saeed Radagdam, Abbas Asoudeh-Fard, Mohammad-Ali Karimi, Yousef Faridvand, Zafar Gholinejad, Siavash Gerayesh Nejad. Calcitriol modulates cholesteryl ester transfer protein (CETP) levels and lipid profile in hypercholesterolemic male rabbits: A pilot study. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2021 Jun; 91(3-4):212-216. doi: 10.1024/0300-9831/a000613. [PMID: 31842709]
  • Martina Feger, Franz Ewendt, Jörg Strotmann, Holger Schäffler, Daniela Kempe-Teufel, Philipp Glosse, Gabriele I Stangl, Michael Föller. Glucocorticoids dexamethasone and prednisolone suppress fibroblast growth factor 23 (FGF23). Journal of molecular medicine (Berlin, Germany). 2021 05; 99(5):699-711. doi: 10.1007/s00109-021-02036-8. [PMID: 33517471]
  • Kamyar Kalantar-Zadeh, Tomas Ganz, Henry Trumbo, Melvin H Seid, Lawrence T Goodnough, Michael A Levine. Parenteral iron therapy and phosphorus homeostasis: A review. American journal of hematology. 2021 05; 96(5):606-616. doi: 10.1002/ajh.26100. [PMID: 33471363]
  • Laleh Mahmoudi, Sara Asadi, Zahra Al-Mousavi, Ramin Niknam. A randomized controlled clinical trial comparing calcitriol versus cholecalciferol supplementation to reduce insulin resistance in patients with non-alcoholic fatty liver disease. Clinical nutrition (Edinburgh, Scotland). 2021 05; 40(5):2999-3005. doi: 10.1016/j.clnu.2020.11.037. [PMID: 33341312]
  • Zhi-Hui Zhang, Biao Luo, Shen Xu, Zhi-Cheng Zhang, Wei-Yang Xing, Yuan-Hua Chen, Cheng Zhang, Hua Wang, Dong-Dong Xie, De-Xiang Xu. Long-term vitamin D deficiency promotes renal fibrosis and functional impairment in middle-aged male mice. The British journal of nutrition. 2021 04; 125(8):841-850. doi: 10.1017/s0007114520003232. [PMID: 32812524]
  • Laura Martínez-Arias, Sara Panizo, Cristina Alonso-Montes, Julia Martín-Vírgala, Beatriz Martín-Carro, Sara Fernández-Villabrille, Carmen García Gil-Albert, Carmen Palomo-Antequera, José Luis Fernández-Martín, María Piedad Ruiz-Torres, Adriana S Dusso, Natalia Carrillo-López, Jorge B Cannata-Andía, Manuel Naves-Díaz. Effects of calcitriol and paricalcitol on renal fibrosis in CKD. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2021 04; 36(5):793-803. doi: 10.1093/ndt/gfaa373. [PMID: 33416889]
  • Mateusz Bosiacki, Izabela Gutowska, Katarzyna Piotrowska, Anna Lubkowska. Concentrations of Ca, Mg, P, Prostaglandin E2 in Bones and Parathyroid Hormone; 1,25-dihydroxyvitamin D3; 17-β-estradiol; Testosterone and Somatotropin in Plasma of Aging Rats Subjected to Physical Training in Cold Water. Biomolecules. 2021 04; 11(5):. doi: 10.3390/biom11050616. [PMID: 33919152]
  • Hamid Yaghooti, Fatemeh Ghanavati, Seyed Saeed Seyedian, Bahman Cheraghian, Narges Mohammadtaghvaei. The efficacy of calcitriol treatment in non-alcoholic fatty liver patients with different genotypes of vitamin D receptor FokI polymorphism. BMC pharmacology & toxicology. 2021 04; 22(1):18. doi: 10.1186/s40360-021-00485-y. [PMID: 33827700]
  • Tetsuo Shoji, Shinya Nakatani, Daijiro Kabata, Katsuhito Mori, Ayumi Shintani, Hisako Yoshida, Kanae Takahashi, Keiko Ota, Hisako Fujii, Shinichiro Ueda, Shinichi Nishi, Tatsuya Nakatani, Minoru Yoshiyama, Kiyoshi Goto, Takayoshi Hamada, Masahito Imanishi, Eiji Ishimura, Sosuke Kagitani, Yoshikazu Kato, Yasuro Kumeda, Kiyoshi Maekawa, Takayasu Matsumura, Harumi Nagayama, Yasue Obi, Yoshiteru Ohno, Yoshinori Sai, Mayumi Sakurai, Satoshi Sasaki, Kaori Shidara, Shigeichi Shoji, Yoshihiro Tsujimoto, Kenjiro Yamakawa, Hideaki Yasuda, Shozo Yodoi, Masaaki Inaba, Masanori Emoto. Comparative Effects of Etelcalcetide and Maxacalcitol on Serum Calcification Propensity in Secondary Hyperparathyroidism: A Randomized Clinical Trial. Clinical journal of the American Society of Nephrology : CJASN. 2021 04; 16(4):599-612. doi: 10.2215/cjn.16601020. [PMID: 33685864]
  • Arthur G Manfro, Mauricio Lutzky, Jose M Dora, Milton A S Kalil, Roberto C Manfro. Case reports of hypercalcemia and chronic renal disease due to cosmetic injections of polymethylmethacrylate (PMMA). Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia. 2021 Apr; 43(2):288-292. doi: 10.1590/2175-8239-jbn-2020-0044. [PMID: 32779690]
  • Gemma Marcucci, Laura Masi, Luisella Cianferotti, Francesca Giusti, Caterina Fossi, Simone Parri, Giorgio Gronchi, Maria Luisa Brandi. Chronic hypoparathyroidism and treatment with teriparatide. Endocrine. 2021 04; 72(1):249-259. doi: 10.1007/s12020-020-02577-x. [PMID: 33538953]
  • Kazunori Inoue, Isao Matsui, Takayuki Hamano, Keiji Okuda, Yasumasa Tsukamoto, Ayumi Matsumoto, Karin Shimada, Seiichi Yasuda, Yusuke Katsuma, Yoshitsugu Takabatake, Masaru Tanaka, Noriko Tanaka, Toshiaki Mano, Tetsuo Minamino, Yasushi Sakata, Yoshitaka Isaka. Maxacalcitol (22-Oxacalcitriol (OCT)) Retards Progression of Left Ventricular Hypertrophy with Renal Dysfunction Through Inhibition of Calcineurin-NFAT Activity. Cardiovascular drugs and therapy. 2021 04; 35(2):381-397. doi: 10.1007/s10557-020-07111-9. [PMID: 33206298]
  • Miribane Dërmaku-Sopjani, Fatbardhë Kurti, Nguyen Thi Xuan, Mentor Sopjani. Klotho-Dependent Role of 1,25(OH)2D3 in the Brain. Neuro-Signals. 2021 03; 29(1):14-23. doi: 10.33594/000000352. [PMID: 33784444]
  • K Zhu, J Zhang, C Zhang, Z Zhao, J Gao, X Li, X Xia, X Xu, T Zhang, J Guan. Therapeutic efficacy of zoledronic acid combined with calcitriol in elderly patients receiving total hip arthroplasty or hemiarthroplasty for osteoporotic femoral neck fracture. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2021 Mar; 32(3):559-564. doi: 10.1007/s00198-020-05637-0. [PMID: 32989470]
  • Anne Schön, Maren Leifheit-Nestler, Jennifer Deppe, Dagmar-Christiane Fischer, Aysun K Bayazit, Lukasz Obrycki, Nur Canpolat, Ipek Kaplan Bulut, Karolis Azukaitis, Alev Yilmaz, Sevgi Mir, Fatos Yalcinkaya, Oguz Soylemezoglu, Anette Melk, Gabriele I Stangl, Rouven Behnisch, Rukshana Shroff, Justine Bacchetta, Uwe Querfeld, Franz Schaefer, Dieter Haffner. Active vitamin D is cardioprotective in experimental uraemia but not in children with CKD Stages 3-5. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2021 02; 36(3):442-451. doi: 10.1093/ndt/gfaa227. [PMID: 33241290]
  • Sepide Kashefiolasl, Matthias S Leisegang, Valeska Helfinger, Christoph Schürmann, Beatrice Pflüger-Müller, Voahanginirina Randriamboavonjy, Andrea E Vasconez, Geert Carmeliet, Klaus Badenhoop, Gudrun Hintereder, Volker Seifert, Katrin Schröder, Juergen Konczalla, Ralf P Brandes. Vitamin D-A New Perspective in Treatment of Cerebral Vasospasm. Neurosurgery. 2021 02; 88(3):674-685. doi: 10.1093/neuros/nyaa484. [PMID: 33269399]
  • Mario E Lacouture, Hedy Dion, Shobha Ravipaty, Joaquin J Jimenez, Khampaseuth Thapa, Eric M Grund, Ely Benaim, Nikunj Tanna, Shen Luan, Nathaniel DiTommaso, Niven R Narain, Rangaprasad Sarangarajan, Elder Granger, Brian Berman, Shari B Goldfarb. A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia. Breast cancer research and treatment. 2021 Feb; 186(1):107-114. doi: 10.1007/s10549-020-06005-6. [PMID: 33206291]
  • Pei-Chang Lee, Yun-Chen Hsieh, Teh-Ia Huo, Ueng-Cheng Yang, Chao-Hsiung Lin, Chung-Pin Li, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin, Kuei-Chuan Lee. Active Vitamin D3 Treatment Attenuated Bacterial Translocation via Improving Intestinal Barriers in Cirrhotic Rats. Molecular nutrition & food research. 2021 02; 65(3):e2000937. doi: 10.1002/mnfr.202000937. [PMID: 33258263]
  • Oleg Tsuprykov, Saban Elitok, Claudia Buse, Chang Chu, Bernhard Karl Krämer, Berthold Hocher. Opposite correlation of 25-hydroxy-vitamin D- and 1,25-dihydroxy-vitamin D-metabolites with gestational age, bone- and lipid-biomarkers in pregnant women. Scientific reports. 2021 01; 11(1):1923. doi: 10.1038/s41598-021-81452-9. [PMID: 33479299]
  • Victor R Lincha, Cheng-Hui Hsiao, Jun Zhao, Chun Li, Diana S-L Chow. Sensitive and rapid UHPLC-MS/MS assay for simultaneous quantifications of calcipotriol and paclitaxel in rat whole blood and plasma samples. Journal of pharmaceutical and biomedical analysis. 2021 Jan; 192(?):113685. doi: 10.1016/j.jpba.2020.113685. [PMID: 33099115]
  • Zizheng Suo, Yanzhi Liu, Yueyi Li, Cong Xu, Yuhan Liu, Mingming Gao, Jinghui Dong. Calcitriol inhibits COX-1 and COX-2 expressions of renal vasculature in hypertension: Reactive oxygen species involved?. Clinical and experimental hypertension (New York, N.Y. : 1993). 2021 Jan; 43(1):91-100. doi: 10.1080/10641963.2020.1817473. [PMID: 32909857]
  • Eri Ito, Yuiko Sato, Tami Kobayashi, Satoshi Nakamura, Yosuke Kaneko, Tomoya Soma, Tatsuaki Matsumoto, Atushi Kimura, Kana Miyamoto, Hideo Matsumoto, Morio Matsumoto, Masaya Nakamura, Kazuki Sato, Takeshi Miyamoto. Food restriction reduces cortical bone mass and serum insulin-like growth factor-1 levels and promotes uterine atrophy in mice. Biochemical and biophysical research communications. 2021 01; 534(?):165-171. doi: 10.1016/j.bbrc.2020.11.122. [PMID: 33288195]
  • A Vieira-Neto, G Negro, R Zimpel, M Poindexter, F Lopes, W W Thatcher, C D Nelson, J E P Santos. Effects of injectable calcitriol on mineral metabolism and postpartum health and performance in dairy cows. Journal of dairy science. 2021 Jan; 104(1):683-701. doi: 10.3168/jds.2020-18448. [PMID: 33162071]
  • Ye Yuan, Supriya Jagga, Janaina S Martins, Rakshya Rana, Paola Divieti Pajevic, Eva S Liu. Impaired 1,25 dihydroxyvitamin D3 action and hypophosphatemia underlie the altered lacuno-canalicular remodeling observed in the Hyp mouse model of XLH. PloS one. 2021; 16(5):e0252348. doi: 10.1371/journal.pone.0252348. [PMID: 34043707]
  • Chunfang Han, Haiying Yu, Qingxia Zhou. Calcitriol Attenuates HRV-Induced Respiratory Injury through the AMPK-mTOR-ER Stress Signaling Pathway. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2021; 40(2):35-43. doi: 10.1615/jenvironpatholtoxicoloncol.2021037112. [PMID: 33822515]
  • Yoshiaki Kanemoto, Akira Hayakawa, Takahiro Sawada, Rei Amano, Tomohiro Kurokawa, Shun Sawatsubashi, Seiji Fukumoto, Jinichi Mori, Shigeaki Kato. Transcriptional Regulation of 25-Hydroxyvitamin D-24-Hydroxylase (CYP24A1) by Calcemic Factors in Keratinocytes. Journal of nutritional science and vitaminology. 2021; 67(6):424-428. doi: 10.3177/jnsv.67.424. [PMID: 34980721]
  • Johanna A Huhtakangas, Jere Huovinen, Sakari Laaksonen, Hanna-Marja Voipio, Olli Vuolteenaho, Mikko A J Finnilä, Jérôme Thevenot, Petri P Lehenkari. A single intra-articular dose of vitamin D analog calcipotriol alleviates synovitis without adverse effects in rats. PloS one. 2021; 16(4):e0250352. doi: 10.1371/journal.pone.0250352. [PMID: 33878143]
  • Sandra Treptow, Joachim Grün, Josephine Scholz, Andreas Radbruch, Guido Heine, Margitta Worm. 9-cis Retinoic acid and 1.25-dihydroxyvitamin D3 drive differentiation into IgA+ secreting plasmablasts in human naïve B cells. European journal of immunology. 2021 01; 51(1):125-137. doi: 10.1002/eji.202048557. [PMID: 33107588]
  • Malgorzata Grzesiak, Gabriela Burzawa, Patrycja Kurowska, Klaudia Blaszczyk, Agata Szlaga, Anna Blasiak, Andrzej Sechman, Agnieszka Rak. Altered vitamin D3 metabolism in the ovary and periovarian adipose tissue of rats with letrozole-induced PCOS. Histochemistry and cell biology. 2021 Jan; 155(1):101-116. doi: 10.1007/s00418-020-01928-z. [PMID: 33095902]
  • Shachi Pranjal Vyas, Rajeshwar Nath Srivastava, Ritobrata Goswami. Calcitriol attenuates TLR2/IL-33 signaling pathway to repress Th9 cell differentiation and potentially limits the pathophysiology of rheumatoid arthritis. Molecular and cellular biochemistry. 2021 Jan; 476(1):369-384. doi: 10.1007/s11010-020-03914-4. [PMID: 32965596]