1,4-Dihydroxy-2-naphthoic acid (BioDeep_00000001709)
Secondary id: BioDeep_00001868545
human metabolite blood metabolite
代谢物信息卡片
1,4-dihydroxynaphthalene-2-carboxylic acid
化学式: C11H8O4 (204.0422568)
中文名称: 1,4-二羟基-2-萘甲酸
谱图信息:
最多检出来源 Homo sapiens(blood) 1.16%
分子结构信息
SMILES: C1=CC=C2C(=C1)C(=CC(=C2O)C(=O)O)O
InChI: InChI=1S/C11H8O4/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,12-13H,(H,14,15)
描述信息
1,4-dihydroxy-2-naphthoate, also known as 1,4-dihydroxy-2-naphthalenecarboxylic acid, is a member of the class of compounds known as naphthalenecarboxylic acids. Naphthalenecarboxylic acids are compounds containing a naphthalene moiety, which bears a carboxylic acid group one or more positions. Naphthalene is a bicyclic compound that is made up of two fused benzene ring. 1,4-dihydroxy-2-naphthoate is practically insoluble (in water) and a moderately acidic compound (based on its pKa). 1,4-dihydroxy-2-naphthoate can be synthesized from 2-naphthoic acid. 1,4-dihydroxy-2-naphthoate can also be synthesized into 1,4-dihydroxy-2-naphthoyl-CoA. 1,4-dihydroxy-2-naphthoate can be found in a number of food items such as rowal, cinnamon, breadfruit, and horseradish, which makes 1,4-dihydroxy-2-naphthoate a potential biomarker for the consumption of these food products.
同义名列表
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:18094
- KEGG: C03657
- PubChem: 671
- HMDB: HMDB0244212
- Metlin: METLIN64746
- ChEMBL: CHEMBL1232286
- MetaCyc: DIHYDROXYNAPHTHOATE
- KNApSAcK: C00000736
- foodb: FDB030191
- chemspider: 651
- CAS: 31519-22-9
- PMhub: MS000001022
- PubChem: 6435
- PDB-CCD: DNA
- 3DMET: B00613
- NIKKAJI: J27.838F
- RefMet: 1,4-Dihydroxy-2-naphthoic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
183 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(183)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
ATP + CoA-SH + O-succinylbenzoate ⟶ 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + AMP + PPi - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - vitamin K1:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA ⟶ 1,4-dihydroxy-2-naphthoate + CoA-SH
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 1744 - Propionibacterium freudenreichii: 10.1271/BBB.66.679
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fabienne Furt, William J Allen, Joshua R Widhalm, Peter Madzelan, Robert C Rizzo, Gilles Basset, Mark A Wilson. Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis.
Acta crystallographica. Section D, Biological crystallography.
2013 Oct; 69(Pt 10):1876-88. doi:
10.1107/s0907444913015771. [PMID: 24100308] - Masayuki Uchida, Hiroshi Tsuboi, Masayo Takahashi Arita, Atsushi Nemoto, Keisuke Seki, Hajime Tsunoo, Stephanie Martyres, Ashley Roberts. Safety of high doses of Propionibacterium freudenreichii ET-3 culture in healthy adult subjects.
Regulatory toxicology and pharmacology : RTP.
2011 Jul; 60(2):262-7. doi:
10.1016/j.yrtph.2010.12.005. [PMID: 21172397] - M Matsubara, E Yamachika, H Tsujigiwa, N Mizukawa, T Ueno, J Murakami, N Ishida, Y Kaneda, N Shirasu, S Takagi. Suppressive effects of 1,4-dihydroxy-2-naphthoic acid administration on bone resorption.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.
2010 Aug; 21(8):1437-47. doi:
10.1007/s00198-009-1075-y. [PMID: 19813044] - Hyun Uk Kim, Chloë van Oostende, Gilles J C Basset, John Browse. The AAE14 gene encodes the Arabidopsis o-succinylbenzoyl-CoA ligase that is essential for phylloquinone synthesis and photosystem-I function.
The Plant journal : for cell and molecular biology.
2008 Apr; 54(2):272-83. doi:
10.1111/j.1365-313x.2008.03416.x. [PMID: 18208520] - Y Okada, Y Tsuzuki, J Miyazaki, K Matsuzaki, R Hokari, S Komoto, S Kato, A Kawaguchi, S Nagao, K Itoh, T Watanabe, S Miura. Propionibacterium freudenreichii component 1.4-dihydroxy-2-naphthoic acid (DHNA) attenuates dextran sodium sulphate induced colitis by modulation of bacterial flora and lymphocyte homing.
Gut.
2006 May; 55(5):681-8. doi:
10.1136/gut.2005.070490. [PMID: 16299037] - O O Barriga. Depression of cell-mediated immunity following inoculation of Trichinella spiralis extract in the mouse.
Immunology.
1978 Jan; 34(1):167-73. doi:
NULL. [PMID: 23994] - . .
.
. doi:
. [PMID: 19321747]