Anhydrotetracyclin (BioDeep_00000001661)

   


代谢物信息卡片


4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide

化学式: C22H22N2O7 (426.1426942)
中文名称: 脱水四环素
谱图信息: 最多检出来源 Homo sapiens(blood) 4.76%

分子结构信息

SMILES: CC1=C2C=CC=C(C2=C(C3=C1CC4C(C(=O)C(=C(C4(C3=O)O)O)C(=O)N)N(C)C)O)O
InChI: InChI=1S/C22H22N2O7/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30)/t11-,16-,22-/m0/s1

描述信息

同义名列表

3 个代谢物同义名

Anhydrotetracycline; Anhydrotetracyclin; 4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Dongmei Xu, Yingping Xiao, Hua Pan, Yu Mei. Toxic effects of tetracycline and its degradation products on freshwater green algae. Ecotoxicology and environmental safety. 2019 Jun; 174(?):43-47. doi: 10.1016/j.ecoenv.2019.02.063. [PMID: 30818259]
  • Min Wang, Qiong Wang, Xiang Gao, Zhong Su. Conditional knock-out of lipoic acid protein ligase 1 reveals redundancy pathway for lipoic acid metabolism in Plasmodium berghei malaria parasite. Parasites & vectors. 2017 Jun; 10(1):315. doi: 10.1186/s13071-017-2253-y. [PMID: 28655332]
  • Murat Topal, Gülşad Uslu Şenel, Erdal Öbek, E Işıl Arslan Topal. Investigation of relationships between removals of tetracycline and degradation products and physicochemical parameters in municipal wastewater treatment plant. Journal of environmental management. 2016 May; 173(?):1-9. doi: 10.1016/j.jenvman.2016.02.046. [PMID: 26950498]
  • Murat Topal, E Işıl Arslan Topal. Occurrence and fate of tetracycline and degradation products in municipal biological wastewater treatment plant and transport of them in surface water. Environmental monitoring and assessment. 2015 Dec; 187(12):750. doi: 10.1007/s10661-015-4978-4. [PMID: 26566643]
  • Martha Ines Burgos, Ricardo Ariel Fernández, María Soledad Celej, Laura Isabel Rossi, Gerardo Daniel Fidelio, Sergio Alberto Dassie. Binding of the highly toxic tetracycline derivative, anhydrotetracycline, to bovine serum albumin. Biological & pharmaceutical bulletin. 2011; 34(8):1301-6. doi: 10.1248/bpb.34.1301. [PMID: 21804222]
  • John Love, George C Allen, Christiane Gatz, William F Thompson. Differential Top10 promoter regulation by six tetracycline analogues in plant cells. Journal of experimental botany. 2002 Sep; 53(376):1871-7. doi: 10.1093/jxb/erf050. [PMID: 12177125]
  • A M Jones, K H Im, M A Savka, M J Wu, N G DeWitt, R Shillito, A N Binns. Auxin-dependent cell expansion mediated by overexpressed auxin-binding protein 1. Science (New York, N.Y.). 1998 Nov; 282(5391):1114-7. doi: 10.1126/science.282.5391.1114. [PMID: 9804548]
  • W B Chang, Y B Zhao, Y X Ci, L Y Hu. Spectrofluorimetric determination of tetracycline and anhydrotetracycline in serum and urine. The Analyst. 1992 Aug; 117(8):1377-8. doi: 10.1039/an9921701377. [PMID: 1443636]
  • M Yanase, Y Orita, N Okada, T Nakanishi, M Horio, A Ando, H Abe. Decreased Na+-gradient-dependent D-glucose transport in brush-border membrane vesicles from rabbits with experimental Fanconi syndrome. Biochimica et biophysica acta. 1983 Aug; 733(1):95-101. doi: 10.1016/0005-2736(83)90094-9. [PMID: 6882758]