Clofenvinfos (BioDeep_00000001620)

   


代谢物信息卡片


(Z)-Chlorfenvinfos

化学式: C12H14Cl3O4P (357.96952640000006)
中文名称: 杀螟威, 毒虫畏
谱图信息: 最多检出来源 Mentha canadensis(plant) 96.3%

分子结构信息

SMILES: CCOP(=O)(OCC)OC(=CCl)C1=C(C=C(C=C1)Cl)Cl
InChI: InChI=1S/C12H14Cl3O4P/c1-3-17-20(16,18-4-2)19-12(8-13)10-6-5-9(14)7-11(10)15/h5-8H,3-4H2,1-2H3

描述信息

D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D010575 - Pesticides > D007306 - Insecticides
D010575 - Pesticides > D056810 - Acaricides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals

同义名列表

4 个代谢物同义名

(Z)-Chlorfenvinfos; Chlorfenvinphos; Chlorfenvinfos; Clofenvinfos



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Lewis Couchman, John A Slaughter, Gemma Coombes, Atholl Johnston, Evans Ogoti, David W Holt. The Smell of Death: An Unusual Case of Poisoning With the Organophosphorus Pesticide Chlorfenvinphos. Therapeutic drug monitoring. 2019 04; 41(2):250-252. doi: 10.1097/ftd.0000000000000584. [PMID: 30883519]
  • Kevin W Wellington, Tlabo Leboho, Bellonah M Sakong, Olubukola T Adenubi, Jacobus N Eloff, Gerda Fouche. Further studies on South African plants: Acaricidal activity of organic plant extracts against Rhipicephalus (Boophilus) microplus (Acari: Ixodidae). Veterinary parasitology. 2017 Jan; 234(?):10-12. doi: 10.1016/j.vetpar.2016.12.014. [PMID: 28115176]
  • Bożena Sosnowska, Bogumiła Huras, Bożena Bukowska. Oxidative stress in human erythrocytes treated with bromfenvinphos and its impurities. Pesticide biochemistry and physiology. 2015 Feb; 118(?):43-9. doi: 10.1016/j.pestbp.2014.11.009. [PMID: 25752429]
  • María Hijosa-Valsero, Ricardo Molina, Hendrik Schikora, Michael Müller, Josep M Bayona. Removal of priority pollutants from water by means of dielectric barrier discharge atmospheric plasma. Journal of hazardous materials. 2013 Nov; 262(?):664-73. doi: 10.1016/j.jhazmat.2013.09.022. [PMID: 24121639]
  • Radosław Swiercz, Piotr Lutz, Sławomir Gralewicz, Zofia Grzelińska, Joanna Piasecka-Zelga, Wojciech Wąsowicz. Partial protection from organophosphate-induced cholinesterase inhibition by metyrapone treatment. International journal of occupational medicine and environmental health. 2013 Aug; 26(4):636-46. doi: 10.2478/s13382-013-0131-1. [PMID: 24052154]
  • Alicja Roszczenko, Joanna Rogalska, Janina Moniuszko-Jakoniuk, Malgorzata M Brzóska. The effect of exposure to chlorfenvinphos on lipid metabolism and apoptotic and necrotic cells death in the brain of rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2013 Jul; 65(5):531-9. doi: 10.1016/j.etp.2012.03.002. [PMID: 22498023]
  • Anna Lukaszewicz-Hussain. [Serum glucose concentration in subacute intoxication with chlorpyrifos - organophosphate insecticide]. Medycyna pracy. 2013; 64(4):527-31. doi: 10.13075/mp.5893.2013.0043. [PMID: 24502117]
  • María A Martínez, Salomé Ballesteros. Two suicidal fatalities due to the ingestion of chlorfenvinphos formulations: simultaneous determination of the pesticide and the petroleum distillates in tissues by gas chromatography-flame-ionization detection and gas chromatography-mass spectrometry. Journal of analytical toxicology. 2012 Jan; 36(1):44-51. doi: 10.1093/jat/bkr014. [PMID: 22290752]
  • Anna Łukaszewicz-Hussain. [Paraoxonase activity and lipid peroxides concentration in serum of rats subchronically intoxicated with chlorpyrifos--organophosphate insecticide]. Medycyna pracy. 2012; 63(5):559-64. doi: . [PMID: 23373324]
  • Sławomir Gralewicz, Piotr Lutz, Radosław Swiercz, Zofia Grzelińska, Dorota Wiaderna. Neuroendocrine and behavioral response to amphetamine challenge after exposure to an organophosphorus pesticide. International journal of occupational medicine and environmental health. 2011 Sep; 24(3):283-91. doi: 10.2478/s13382-011-0023-1. [PMID: 21792578]
  • Tania Portolés, Elena Pitarch, Francisco J López, Félix Hernández. Development and validation of a rapid and wide-scope qualitative screening method for detection and identification of organic pollutants in natural water and wastewater by gas chromatography time-of-flight mass spectrometry. Journal of chromatography. A. 2011 Jan; 1218(2):303-15. doi: 10.1016/j.chroma.2010.11.010. [PMID: 21134677]
  • Anna Łukaszewicz-Hussain. [Liver and serum glutathione concentration and liver hydrogen peroxide in rats subchronically intoxicated with chlorfenvinphos--organophosphate insecticide]. Medycyna pracy. 2011; 62(1):23-9. doi: . [PMID: 21748880]
  • Robinson H Mdegela, Resto D Mosha, Morten Sandvik, Janneche U Skaare. Assessment of acetylcholinesterase activity in Clarias gariepinus as a biomarker of organophosphate and carbamate exposure. Ecotoxicology (London, England). 2010 Jun; 19(5):855-63. doi: 10.1007/s10646-010-0466-3. [PMID: 20169407]
  • F M Mahdy, S I El-Maghraby. Effect of processing on 14C-chlorfenvinphos residues in maize oil and bioavailability of its cake residues on rats. Bulletin of environmental contamination and toxicology. 2010 May; 84(5):582-6. doi: 10.1007/s00128-010-9984-1. [PMID: 20405102]
  • N Klamerth, S Malato, M I Maldonado, A Agüera, A R Fernández-Alba. Application of photo-fenton as a tertiary treatment of emerging contaminants in municipal wastewater. Environmental science & technology. 2010 Mar; 44(5):1792-8. doi: 10.1021/es903455p. [PMID: 20131796]
  • Slawomir Gralewicz, Radoslaw Swiercz, Piotr Lutz, Dorota Wiaderna, Wojciech Wasowicz. Effects of stress pretreatment on the dynamics of blood cholinesterase activity after exposure to an organophosphorus pesticide in the rat. Annals of agricultural and environmental medicine : AAEM. 2010; 17(1):65-71. doi: . [PMID: 20684482]
  • Tania Portolés, María Ibáñez, Juan V Sancho, Francisco J López, Félix Hernández. Combined use of GC-TOF MS and UHPLC-(Q)TOF MS to investigate the presence of nontarget pollutants and their metabolites in a case of honeybee poisoning. Journal of agricultural and food chemistry. 2009 May; 57(10):4079-90. doi: 10.1021/jf900099u. [PMID: 19382786]
  • Rosa Ma González-Rodríguez, Raquel Rial-Otero, Beatriz Cancho-Grande, Jesús Simal-Gándara. Determination of 23 pesticide residues in leafy vegetables using gas chromatography-ion trap mass spectrometry and analyte protectants. Journal of chromatography. A. 2008 Jul; 1196-1197(?):100-9. doi: 10.1016/j.chroma.2008.02.087. [PMID: 18343389]
  • Mabruka H Tarhoni, Timothy Lister, David E Ray, Wayne G Carter. Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2008 Jun; 13(4):343-63. doi: 10.1080/13547500801973563. [PMID: 18484351]
  • Anna Lukaszewicz-Hussain. Subchronic intoxication with chlorfenvinphos, an organophosphate insecticide, affects rat brain antioxidative enzymes and glutathione level. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Jan; 46(1):82-6. doi: 10.1016/j.fct.2007.06.038. [PMID: 17706853]
  • Anna Cieniecka-Rosłonkiewicz, Agnieszka Sas, Elzbieta Przybysz, Bolesław Morytz, Anna Syguda, Juliusz Pernak. Ionic liquids for the production of insecticidal and microbicidal extracts of the fungus Cantharellus cibarius. Chemistry & biodiversity. 2007 Sep; 4(9):2218-24. doi: 10.1002/cbdv.200790179. [PMID: 17886840]
  • M J Gómez, M J Martínez Bueno, S Lacorte, A R Fernández-Alba, A Agüera. Pilot survey monitoring pharmaceuticals and related compounds in a sewage treatment plant located on the Mediterranean coast. Chemosphere. 2007 Jan; 66(6):993-1002. doi: 10.1016/j.chemosphere.2006.07.051. [PMID: 16962638]
  • M I Maldonado, S Malato, L A Pérez-Estrada, W Gernjak, I Oller, Xavier Doménech, José Peral. Partial degradation of five pesticides and an industrial pollutant by ozonation in a pilot-plant scale reactor. Journal of hazardous materials. 2006 Nov; 138(2):363-9. doi: 10.1016/j.jhazmat.2006.05.058. [PMID: 16822610]
  • Nina Cedergreen, Anja Kamper, Jens C Streibig. Is prochloraz a potent synergist across aquatic species? A study on bacteria, daphnia, algae and higher plants. Aquatic toxicology (Amsterdam, Netherlands). 2006 Jun; 78(3):243-52. doi: 10.1016/j.aquatox.2006.03.007. [PMID: 16672166]
  • Milena Lapertot, César Pulgarín, Pilar Fernández-Ibáñez, Manuel I Maldonado, Leonidas Pérez-Estrada, Isabel Oller, Wolfgang Gernjak, Sixto Malato. Enhancing biodegradability of priority substances (pesticides) by solar photo-Fenton. Water research. 2006 Mar; 40(5):1086-94. doi: 10.1016/j.watres.2006.01.002. [PMID: 16469356]
  • Howard C Bailey, James R Elphick, Rick Krassoi, Ann-Marie Mulhall, Adam J Lovell, Daniel J Slee. Identification of chlorfenvinphos toxicity in a municipal effluent in Sydney, New South Wales, Australia. Environmental toxicology and chemistry. 2005 Jul; 24(7):1773-8. doi: 10.1897/04-366r.1. [PMID: 16050596]
  • Sławomir Gralewicz, Piotr Lutz, Barbara Kur. Pretreatment with footshock alters some effects of subsequent organophosphate exposure. Neurotoxicology. 2005 Mar; 26(2):159-71. doi: 10.1016/j.neuro.2004.12.003. [PMID: 15713337]
  • W A Collier, M Clear, A L Hart. Convenient and rapid detection of pesticides in extracts of sheep wool. Biosensors & bioelectronics. 2002 Sep; 17(9):815-9. doi: 10.1016/s0956-5663(02)00074-x. [PMID: 12191930]
  • S Kossmann, B Konieczny. [Serum immunoglobulin E concentration in workers producing chlorfenvinphos]. Przeglad lekarski. 2001; 58 Suppl 7(?):49-50. doi: . [PMID: 11957784]
  • B Konieczny, S Kossmann, M Makuch. Impaired respiratory muscle function in chemical plant workers producing chlorfenvinphos. Annals of agricultural and environmental medicine : AAEM. 1999; 6(1):21-5. doi: . [PMID: 10384211]
  • R Soćko, S Gralewicz, R Górny. Long-term behavioural effects of a repeated exposure to chlorphenvinphos in rats. International journal of occupational medicine and environmental health. 1999; 12(2):105-17. doi: . [PMID: 10465900]
  • A Lukaszewicz-Hussain, J Moniuszko-Jakoniuk. [The impact of acute poisoning by chlorfenvinphos on the activity of antioxidant enzymes and concentration of malondialdehyde in rats]. Roczniki Panstwowego Zakladu Higieny. 1999; 50(3):307-11. doi: . [PMID: 10628227]
  • P K Mohapatra, U Schiewer. Effect of dimethoate and chlorfenvinphos on plasma membrane integrity of Synechocystis sp. PCC 6803. Ecotoxicology and environmental safety. 1998 Nov; 41(3):269-74. doi: 10.1006/eesa.1998.1708. [PMID: 9799578]
  • A Lukaszewicz-Hussain, J Moniuszko-Jakoniuk. [Changes in rats liver in late period of intoxication with chlorphenvinphos in a single dose]. Roczniki Panstwowego Zakladu Higieny. 1998; 49(3):313-9. doi: . [PMID: 9930024]
  • M Podolak, L Panasiuk. Biological indicators for the assessment of human exposure to organophosphorous compounds. Przeglad lekarski. 1997; 54(10):719-22. doi: NULL. [PMID: 9478093]
  • P Kłuciński, S Kossmann, D Friedek. Release of interleukin-1 beta from peripheral blood monocytes and its concentration in the blood serum of the workers employed at the production of chlorfenvinphos. Przeglad lekarski. 1997; 54(10):716-8. doi: . [PMID: 9478092]
  • S Kossmann, E Cierpka, Z Szwed. Biochemical evaluation of the liver function in workers employed at the production of chlorfenvinphos. Przeglad lekarski. 1997; 54(10):712-5. doi: . [PMID: 9478091]
  • L Sedrowicz, D Witkowska, R Oledzka. Effect of chlorfenvinphos, cypermethrin and their mixture on the intestinal transport of leucine and methionine. Journal of applied toxicology : JAT. 1996 Nov; 16(6):483-9. doi: 10.1002/(sici)1099-1263(199611)16:6<483::aid-jat380>3.0.co;2-d. [PMID: 8956093]
  • N D Sargison, P R Scott, C J Clarke, C D Penny, R S Pirie. Severe post-dipping dermatitis and subcutaneous fluid swellings associated with two outbreaks of sheep scab (Psoroptes ovis infestation). The Veterinary record. 1995 Mar; 136(9):217-20. doi: 10.1136/vr.136.9.217. [PMID: 7771071]
  • K I Zaleska-Freljan, J T Wolewicz. Influence of bromfenvinphos alone, and in mixture with methoxychlor, on levels of gamma-glutamyl transpeptidase, ceruloplasmin and cholesterol in the blood plasma of laboratory mice. Polish journal of pharmacology. 1993 May; 45(3):309-16. doi: NULL. [PMID: 8106090]
  • J Dudka, S Szczepaniak. [Investigation of chlorfenvinphos influence on levels of free tryptophan in blood plasma of the rat]. Roczniki Panstwowego Zakladu Higieny. 1993; 44(2-3):199-203. doi: NULL. [PMID: 8016542]
  • J Błasiak. Changes in the fluidity of model lipid membranes evoked by the organophosphorus insecticide methylbromfenvinfos. Acta biochimica Polonica. 1993; 40(1):39-41. doi: ". [PMID: 8372562]
  • M A Chishti, T Rotkiewicz. Hepatic and renal ultrastructural changes in cockerels exposed to cadmium chloride and subsequent interaction with organophosphate insecticide. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 1993 Jan; 12(1):35-45. doi: . [PMID: 8459366]
  • M A Chishti, T Rotkiewicz. Ultrastructural alterations produced in cockerels after mercuric chloride toxicity and subsequent interaction with an organophosphate insecticide. Archives of environmental contamination and toxicology. 1992 May; 22(4):445-51. doi: 10.1007/bf00212565. [PMID: 1586206]
  • T Ikeda, S Tsuda, Y Shirasu. Pharmacokinetic analysis of protection by an organophosphorus insecticide, chlorfenvinphos, against the toxicity of its succeeding dosage in rats. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1992 Feb; 18(2):299-306. doi: 10.1016/0272-0590(92)90059-q. [PMID: 1601231]
  • J Rouchaud, F Gustin, F Benoit, N Ceustermans, J Gillet, F Van de Steene, C Pelerents. Influence of cow manure and composts on the effects of chlorfenvinphos on field crops. Archives of environmental contamination and toxicology. 1992 Jan; 22(1):122-9. doi: 10.1007/bf00213310. [PMID: 1313223]
  • H Maciejewska-Kozak, S Szczepaniak, K Jeleniewicz. [Examination of the effect of chlorfenvinphos on the activity of aminotransferase in plasma and liver in vitro]. Roczniki Panstwowego Zakladu Higieny. 1992; 43(1):67-73. doi: NULL. [PMID: 1465557]
  • T Ikeda, S Tsuda, Y Shirasu. Metabolic induction of the hepatic cytochrome P450 system by chlorfenvinphos in rats. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1991 Aug; 17(2):361-7. doi: 10.1016/0272-0590(91)90225-s. [PMID: 1765223]
  • S Gralewicz, T Tomas, R Górny, W Kowalczyk, R Soćko. Changes in brain bioelectrical activity (EEG) after repetitive exposure to an organo-phosphate anticholinesterase. II. Rat. Polish journal of occupational medicine and environmental health. 1991; 4(2):183-96. doi: . [PMID: 1799644]
  • J Ochyński. Dynamics of excretion (14C) bromfenvinphos in rats and dogs. Polish journal of occupational medicine and environmental health. 1991; 4(4):359-75. doi: NULL. [PMID: 1817684]
  • T Ikeda, T Kojima, M Yoshida, H Takahashi, S Tsuda, Y Shirasu. Pretreatment of rats with an organophosphorus insecticide, chlorfenvinphos, protects against subsequent challenge with the same compound. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1990 Apr; 14(3):560-7. doi: 10.1016/0272-0590(90)90260-q. [PMID: 2340983]
  • D Pawłowska, J Moniuszko-Jakoniuk, A Lukaszewicz-Hussain. [Effect of pesticides on selected biochemical parameters in the serum and liver of rats]. Roczniki Akademii Medycznej w Bialymstoku = Annales Academiae Medicae Bialostocensis. 1990 199; 35-36(?):143-61. doi: NULL. [PMID: 2136543]
  • S Gralewicz, W Kowalczyk, R Górny, R Soćko. Brain electrical activity (EEG) after repetitive exposure to chlorphenvinphos an organophosphate anticholinesterase: I. Rabbit. Polish journal of occupational medicine. 1990; 3(1):51-67. doi: . [PMID: 2132936]
  • J Rouchaud, F Gustin, F Van de Steene, C Pelerents, J Gillet, F Benoit, N Ceustermans, L Vanparys. Metabolism of chlorfenvinphos in both soil and plant of cauliflower and brussels sprouts field crops. Bulletin of environmental contamination and toxicology. 1989 Dec; 43(6):920-8. doi: 10.1007/bf01702066. [PMID: 2597799]
  • S Gralewicz, T Tomas, R Górny, W Kowalczyk, R Soćko. Changes in physiological and electrophysiological parameters in rabbits after single exposure to chlorphenvinphos. Polish journal of occupational medicine. 1989; 2(1):3-14. doi: . [PMID: 2489411]
  • R Soćko, S Gralewicz, R Górny. Neurotoxicity of chlorphenvinphos an organophosphorus pesticide: effects on blood and brain cholinesterase activity, open field behavior and response-to-change in a "T" maze in rats. Polish journal of occupational medicine. 1989; 2(3):294-308. doi: . [PMID: 2489432]
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  • A Osicka-Koprowska, M Lipska, B Wysocka-Paruszewska. Effects of chlorfenvinphos on plasma corticosterone and aldosterone levels in rats. Archives of toxicology. 1984 Mar; 55(1):68-9. doi: 10.1007/bf00316589. [PMID: 6732507]
  • L Puzyńska. Alterations in some biochemical processes in the organism of rats being under the influence of chlorfenvinphos administered in diets with variable protein content. Die Nahrung. 1984; 28(5):473-82. doi: 10.1002/food.19840280503. [PMID: 6482945]
  • T Skwarek, L Jabłoński. [In vitro studies of the effect of organophosphate compounds on the surface structure of monkey kidney cells]. Medycyna doswiadczalna i mikrobiologia. 1984; 36(2):129-33. doi: NULL. [PMID: 6092795]
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  • K I Zaleska-Freljan, B Kosicka, B Zbiegieni. The histological changes in some organs of the laboratory mice after intragastrically given bromfenvinphos and mixture of bromfenvinphos with methoxychlor. Polish journal of pharmacology and pharmacy. 1983 May; 35(3):185-93. doi: NULL. [PMID: 6622299]
  • W M Jay, R W Marcus, M S Jay. Primary position upbeat nystagmus with organophosphate poisoning. Journal of pediatric ophthalmology and strabismus. 1982 Nov; 19(6):318-9. doi: 10.3928/0191-3913-19821101-09. [PMID: 7153825]
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  • S Szczepaniak, E Sienkiewicz. [Effect of chlorfenvinphos on biochemical processes in the body]. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina. 1982; 37(?):45-51. doi: NULL. [PMID: 6927083]
  • K I Zaleska-Freljan, B Kosicka. Influence of bromfenvinfos alone and in mixture with methoxychlor on the blood indices of laboratory mice. Polish journal of pharmacology and pharmacy. 1982; 34(4):187-92. doi: . [PMID: 7182839]
  • E Sienkiewicz, S Szczepaniak. [Changes in the concentration of serum amino acids in rats after acute chlorfenvinphos poisoning, determined by thin-layer chromatography]. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina. 1981; 36(?):247-51. doi: NULL. [PMID: 7052770]
  • J Ochyński. [Binding of bromfenvinphos-C-14 with rat and dog serum proteins]. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina. 1980; 35(?):25-32. doi: NULL. [PMID: 7349073]