Anilofos (BioDeep_00000001562)

 

Secondary id: BioDeep_00000408776

human metabolite blood metabolite


代谢物信息卡片


O,O-Dimethyl ({[(4-chlorophenyl)(propan-2-yl)carbamoyl]methyl}sulphanyl)phosphonothioic acid

化学式: C13H19ClNO3PS2 (367.0232)
中文名称: 莎稗磷
谱图信息: 最多检出来源 Homo sapiens(blood) 97.5%

分子结构信息

SMILES: CC(C)N(C1=CC=C(C=C1)Cl)C(=O)CSP(=S)(OC)OC
InChI: InChI=1S/C13H19ClNO3PS2/c1-10(2)15(12-7-5-11(14)6-8-12)13(16)9-21-19(20,17-3)18-4/h5-8,10H,9H2,1-4H3



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 ANXA5, CAT, HPGDS
Peripheral membrane protein 3 ACHE, ANXA5, CTSB
Nucleus 1 ACHE
cytosol 3 ANXA5, CAT, HPGDS
nucleoplasm 2 ATP2B1, HPGDS
Cell membrane 2 ACHE, ATP2B1
Multi-pass membrane protein 1 ATP2B1
Synapse 2 ACHE, ATP2B1
cell surface 1 ACHE
glutamatergic synapse 1 ATP2B1
Golgi apparatus 1 ACHE
neuromuscular junction 1 ACHE
presynaptic membrane 1 ATP2B1
sarcolemma 1 ANXA5
Lysosome 1 CTSB
plasma membrane 3 ACHE, ATP2B1, BCHE
synaptic vesicle membrane 1 ATP2B1
Membrane 4 ACHE, ANXA5, ATP2B1, CAT
apical plasma membrane 1 CTSB
basolateral plasma membrane 1 ATP2B1
extracellular exosome 4 ANXA5, ATP2B1, CAT, CTSB
extracellular space 3 ACHE, BCHE, CTSB
perinuclear region of cytoplasm 2 ACHE, CTSB
mitochondrion 1 CAT
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 3 ATP2B1, CAT, HPGDS
Secreted 2 ACHE, BCHE
extracellular region 5 ACHE, ANXA5, BCHE, CAT, CTSB
mitochondrial matrix 1 CAT
Extracellular side 2 ACHE, CTSB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 2 ANXA5, CTSB
Apical cell membrane 1 CTSB
focal adhesion 2 ANXA5, CAT
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 2 ANXA5, CTSB
lateral plasma membrane 1 ATP2B1
Zymogen granule membrane 1 ANXA5
cell projection 1 ATP2B1
Secreted, extracellular space 1 CTSB
blood microparticle 1 BCHE
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
Melanosome 1 CTSB
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
ficolin-1-rich granule lumen 2 CAT, CTSB
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 BCHE
immunological synapse 1 ATP2B1
nuclear envelope lumen 1 BCHE
vesicle membrane 1 ANXA5
synaptic cleft 1 ACHE
peptidase inhibitor complex 1 CTSB
catalase complex 1 CAT
endolysosome lumen 1 CTSB
endothelial microparticle 1 ANXA5
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • Poonam Sharma, Rambir Singh. Dichlorvos and lindane induced oxidative stress in rat brain: Protective effects of ginger. Pharmacognosy research. 2012 Jan; 4(1):27-32. doi: 10.4103/0974-8490.91031. [PMID: 22224058]
  • Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays. Toxicology. 2011 Feb; 280(3):77-87. doi: 10.1016/j.tox.2010.11.008. [PMID: 21115097]
  • Jun Zhang, Jin-Wei Zheng, Bao-Jian Hang, Ying-Ying Ni, Jian He, Shun-Peng Li. Rhodanobacter xiangquanii sp. nov., a novel anilofos-degrading bacterium isolated from a wastewater treating system. Current microbiology. 2011 Feb; 62(2):645-9. doi: 10.1007/s00284-010-9757-4. [PMID: 20936473]
  • Archana Hazarika, S N Sarkar, Sunil Hajare, Meena Kataria, J K Malik. Influence of malathion pretreatment on the toxicity of anilofos in male rats: a biochemical interaction study. Toxicology. 2003 Mar; 185(1-2):1-8. doi: 10.1016/s0300-483x(02)00574-7. [PMID: 12505439]
  • Fayez A Bakry, Adel A Sakrane, Nahed M M Ismail. Molluscicidal effect of fungicide, herbicide and plant extract on some biological and physiological parameters of Biomphalaria alexandrina. Journal of the Egyptian Society of Parasitology. 2002 Dec; 32(3):821-35. doi: . [PMID: 12512815]
  • Z H Zidan, F M A Ragab, K H A Mohamed. Molluscicidal activities of certain pesticide and their mixtures against Biomphalaria alexandrina. Journal of the Egyptian Society of Parasitology. 2002 Apr; 32(1):285-96. doi: . [PMID: 12049263]
  • A Hazarika, S N Sarkar. Subacute toxicity of anilofos, a new organophosphorus herbicide, in male rats: effect on some physical attributes and acetylcholinesterase activity. Indian journal of experimental biology. 2001 Nov; 39(11):1107-12. doi: . [PMID: 11906102]
  • A Hazarika, S N Sarkar, M Kataria. Subacute toxicity of anilofos, a new organophosphorus herbicide in male rats: effect on lipid peroxidation and ATPase activity. Indian journal of experimental biology. 2001 Nov; 39(11):1113-7. doi: . [PMID: 11906103]
  • A Hazarika, S N Sarkar. Effect of isoproturon pretreatment on the biochemical toxicodynamics of anilofos in male rats. Toxicology. 2001 Aug; 165(2-3):87-95. doi: 10.1016/s0300-483x(01)00411-5. [PMID: 11522367]