Warfarin (BioDeep_00000001524)

Main id: BioDeep_00000015385

 

human metabolite blood metabolite


代谢物信息卡片


4-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one

化学式: C19H16O4 (308.1048536)
中文名称: S-文拉法辛, R-文拉法辛, 华法林
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)CC(C1=CC=CC=C1)C1=C(O)C2=C(OC1=O)C=CC=C2
InChI: InChI=1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3

描述信息

Warfarin is an anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
B - Blood and blood forming organs > B01 - Antithrombotic agents > B01A - Antithrombotic agents > B01AA - Vitamin k antagonists
C78275 - Agent Affecting Blood or Body Fluid > C263 - Anticoagulant Agent > C173064 - Vitamin K Antagonist
D006401 - Hematologic Agents > D000925 - Anticoagulants > D015110 - 4-Hydroxycoumarins
D010575 - Pesticides > D012378 - Rodenticides
D016573 - Agrochemicals

同义名列表

134 个代谢物同义名

4-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one; 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one; 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one; 3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin; (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone; 3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin; 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one; (Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine; (Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin; 1-(4-Hydroxy-3-coumarinyl)-1-phenyl-3-butanone; Bristol-myers squibb brand OF warfarin sodium; DL-3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin; 3-(1-Phenyl-2-acetylethyl)-4-hydroxycoumarin; 4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine; 4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin; 4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine; 3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin; 4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine; 4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine; 4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine; 4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin; 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin; 3-(Acetonylbenzyl)-4-hydroxycoumarin; RCR Grey squirrel killer concentrate; Goldshield brand OF warfarin sodium; Genpharm brand OF warfarin sodium; Antigen brand OF warfarin sodium; Apotex brand OF warfarin sodium; Estedi brand OF warfarin sodium; Bailly brand OF warfarin sodium; Boots brand OF warfarin sodium; Rattenstreupulver new schacht; Rattenstreupulver neu schacht; aldo Brand OF warfarin sodium; Spray-trol brand roden-trol; Rough and ready mouse mix; Rough & ready mouse mix; Eastern states duocide; fasco Fascrat powder; Twin light rat away; (±)-Warfarin; 4oh-Coumarin deriv.; Potassium, warfarin; Warfarin potassium; Maag rattentod cum; Killgerm sewarin P; Rat and mice bait; Ratten-koederrohr; Sodium, warfarin; Rat-O-cide no. 2; MartinS mar-frin; (S)-(−)-Warfarin; Rat & mice bait; Warfarin sodium; Vampirinip III; Arab rat death; Arab rat deth; Rattentraenke; Rat-alpha-way; Rat-O-cide #2; Vampirinip II; Athrombine-K; Rat-beta-gon; Rats-NO-more; Prothromadin; Frass-ratron; (+)-Warfarin; Gen-warfarin; apo-Warfarin; 200 Coumarin; (-)-Warfarin; Zoocoumarin; Compound 42; Athrombin-K; Sorexa plus; Rodafarin c; Rodex blox; Coumaphene; Coumefene; Warfarine; Coumaphen; Dicusat e; Coumafene; Rat-b-gon; Rat-a-way; delta-CON; Coumarins; Aldocumar; Liqua-tox; Coumadine; Rodafarin; Tedicumar; Place-pax; Cov-R-tox; Mouse pak; Coumafen; Kypfarin; Brumolin; Latka 42; Rat-trol; Solfarin; Coumadin; Rat-gard; Rattunal; Rat-kill; warfarin; Ratron g; Mar-frin; Ratoxin; Rat-ola; Warfant; Dethmor; Kumader; Rat-mix; ro-Deth; Maveran; Dethnel; Temus W; Kumatox; Sewarin; Sakarat; Ratorex; Marevan; Tox-hid; Kumadu; Choice; CO-Rax; Ratron; Rosex; Waran; Rodex; D-CON; Ratox; RAX



数据库引用编号

25 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Qiang Zhou, Xiang Liu, Zhi-Chun Gu, Xian Yang, Xiao-Hui Huang, Yan-Zi Wu, Ying-Ying Tao, Meng Wei. Short-term antiplatelet versus anticoagulant therapy after left atrial appendage closure: a systematic review and meta-analysis. Journal of thrombosis and thrombolysis. 2024 Feb; 57(2):194-203. doi: 10.1007/s11239-023-02919-2. [PMID: 38180590]
  • Xiaozheng Wu, Wen Li, Zhenliang Luo, Yunzhi Chen. A comprehensive comparison of the safety and efficacy of drugs in the treatment of idiopathic pulmonary fibrosis: a network meta-analysis based on randomized controlled trials. BMC pulmonary medicine. 2024 Jan; 24(1):58. doi: 10.1186/s12890-024-02861-w. [PMID: 38281037]
  • Shenxin Lu, Jie Chen, Rui Zhang, Tiancheng Luo, Lili Ma, Pengju Xu, Hong Ding, Xiaoqing Zeng, Bing Wu, Yihai Shi, Chenghai Liu, Yongping Mu, Shiyao Chen, Jian Wang. Comparative effectiveness of warfarin in cirrhotic patients with non-symptomatic portal vein thrombosis: a multicenter, randomized controlled trial. Expert review of gastroenterology & hepatology. 2024 Jan; 18(1-3):5-12. doi: 10.1080/17474124.2024.2307575. [PMID: 38236640]
  • Xin-Yi Gao, Yue-Ming Liu, Dan-Na Zheng, Yi-Wen Li, Hua Li, Xiao-Ling Xiong, Hong-Yu Chen, Hua Wang, Xiao-Yong Yu, Kai Qu, Juan Jin, Bo Lin, Qiang He. Comparison of the prophylactic antithrombotic effect of indobufen and warfarin in patients with nephrotic syndrome: a randomized controlled trial. Renal failure. 2023 Dec; 45(1):2163505. doi: 10.1080/0886022x.2022.2163505. [PMID: 36636998]
  • Yi-Hsin Chan, Tze-Fan Chao, Shao-Wei Chen, Hsin-Fu Lee, Pei-Ru Li, Yung-Hsin Yeh, Chi-Tai Kuo, Lai-Chu See, Gregory Y H Lip. Clinical Outcomes in Elderly Atrial Fibrillation Patients at Increased Bleeding Risk Treated with Very-Low-Dose versus Regular-Dose Non-Vitamin K Antagonist Oral Anticoagulants: a Nationwide Cohort Study. European heart journal. Cardiovascular pharmacotherapy. 2023 Aug; ?(?):. doi: 10.1093/ehjcvp/pvad058. [PMID: 37580139]
  • Caroline Nb Clezar, Carolina Dq Flumignan, Nicolle Cassola, Luis Cu Nakano, Virginia Fm Trevisani, Ronald Lg Flumignan. Pharmacological interventions for asymptomatic carotid stenosis. The Cochrane database of systematic reviews. 2023 Aug; 8(?):CD013573. doi: 10.1002/14651858.cd013573.pub2. [PMID: 37565307]
  • Jiali Gu, Hongrui Liu, Xiyao Huang, Yanxuan Ma, Liang Zhang. Investigation of the separate and simultaneous bindings of warfarin and fenofibrate to bovine serum albumin. International journal of biological macromolecules. 2023 Mar; 236(?):123978. doi: 10.1016/j.ijbiomac.2023.123978. [PMID: 36906198]
  • Paula M Leite, Ana P N Miranda, Izabella Gomes, Maria L Rodrigues, Layla M Camargos, Juliana M Amorim, Rita C F Duarte, André A G Faraco, Maria G Carvalho, Rachel O Castilho. Antithrombotic potential of Lippia alba: A mechanistic approach. Journal of ethnopharmacology. 2023 Jan; 301(?):115744. doi: 10.1016/j.jep.2022.115744. [PMID: 36181984]
  • Marie Moussouni, Véronique Graff, Franck Couturier, Hugo Herrscher. Drug interactions causing warfarin overdose in a patient with a pancreatic cancer : a case report. Chemotherapy. 2022 Nov; ?(?):. doi: 10.1159/000528063. [PMID: 36446317]
  • Tal Hirschhorn, Brent R Stockwell. Vitamin K: A new guardian against ferroptosis. Molecular cell. 2022 10; 82(20):3760-3762. doi: 10.1016/j.molcel.2022.10.001. [PMID: 36270246]
  • Juan Tamargo, Juan Carlos Kaski, Takeshi Kimura, Jack Charles Barton, Ko Yamamoto, Maki Komiyama, Heinz Drexel, Basil S Lewis, Stefan Agewall, Koji Hasegawa. Racial and ethnic differences in pharmacotherapy to prevent coronary artery disease and thrombotic events. European heart journal. Cardiovascular pharmacotherapy. 2022 Sep; 8(7):738-751. doi: 10.1093/ehjcvp/pvac040. [PMID: 35848895]
  • Zhen Wang, Zhe Wang, Xiaoyu Wang, Xin Lv, Hang Yin, Lili Jiang, Yangliu Xia, Wei Li, Wenli Li, Yong Liu. Potential food-drug interaction risk of thymoquinone with warfarin. Chemico-biological interactions. 2022 Sep; 365(?):110070. doi: 10.1016/j.cbi.2022.110070. [PMID: 35921950]
  • Yan Li, Jing-Ping Ge, Ke Ma, Yuan-Yuan Yin, Juan He, Jian-Ping Gu. The combination of EGCG with warfarin reduces deep vein thrombosis in rabbits through modulating HIF-1α and VEGF via the PI3K/AKT and ERK1/2 signaling pathways. Chinese journal of natural medicines. 2022 Sep; 20(9):679-690. doi: 10.1016/s1875-5364(22)60172-9. [PMID: 36162953]
  • Madison N Irwin, Sarah Adie, Katherine Sandison, Sarah A Alsomairy, Adamo Brancaccio. Warfarin Dose Requirements in Adults Hospitalized With COVID-19 Infection: A Retrospective Case Series. Journal of pharmacy practice. 2022 Aug; 35(4):654-660. doi: 10.1177/08971900211000705. [PMID: 33719699]
  • Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-Ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A Pratt, Marcus Conrad. A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature. 2022 08; 608(7924):778-783. doi: 10.1038/s41586-022-05022-3. [PMID: 35922516]
  • Maor Wanounou, Chanan Shaul, Zahi Abu Ghosh, Shoshana Alamia, Yoseph Caraco. The Impact of CYP2C9*11 Allelic Variant on the Pharmacokinetics of Phenytoin and (S)-Warfarin. Clinical pharmacology and therapeutics. 2022 07; 112(1):156-163. doi: 10.1002/cpt.2613. [PMID: 35426132]
  • Antoine Pham, Adele Heib, Emily Goodman, Ryan Cotto, Parmida Jafari, Evan Lipsitz, Jeffrey Indes. Warfarin versus direct oral anticoagulants for patients needing distal deep vein thrombosis treatment. Journal of vascular surgery. Venous and lymphatic disorders. 2022 07; 10(4):826-831.e1. doi: 10.1016/j.jvsv.2022.01.006. [PMID: 35124243]
  • Shaojun Jiang, Meina Lv, Zhiwei Zeng, Zongwei Fang, Mingrong Chen, Jiafen Qian, Tingting Wu, Wenjun Chen, Jinhua Zhang. Efficacy and safety of app-based remote warfarin management during COVID-19-related lockdown: a retrospective cohort study. Journal of thrombosis and thrombolysis. 2022 Jul; 54(1):20-28. doi: 10.1007/s11239-021-02630-0. [PMID: 35092566]
  • Tuncay Güzel, Adem Aktan, Raif Kılıç, Bayram Arslan, Baran Arık, Merve Yentür, Halil Yıldız, Lokman Argun, Kamran İldırımlı, Bünyamin Yıldırım, Muhammed Demir, Mehmet Özbek, Faruk Ertaş. Oral Anticoagulant Use and Long-Term Follow-Up Results in Patients with Non-valvular Atrial Fibrillation in Turkey AFTER-2 Study. Anatolian journal of cardiology. 2022 Jul; 26(7):567-576. doi: 10.5152/anatoljcardiol.2022.1597. [PMID: 35791713]
  • Sajidah Alkhameys, Ravina Barrett. Impact of the COVID-19 pandemic on England's national prescriptions of oral vitamin K antagonist (VKA) and direct-acting oral anticoagulants (DOACs): an interrupted time series analysis (January 2019-February 2021). Current medical research and opinion. 2022 Jul; 38(7):1081-1092. doi: 10.1080/03007995.2022.2078100. [PMID: 35582854]
  • M E Bauman, A Hellinger, C Vander Pluym, R Bhat, E Simpson, M Mehegan, P Knox, M P Massicotte. Online KidClot education for patients and families initiating warfarin therapy: The eKITE study. Thrombosis research. 2022 07; 215(?):14-18. doi: 10.1016/j.thromres.2022.05.003. [PMID: 35594736]
  • Tatsiana Vaitsiakhovich, Craig I Coleman, Frank Kleinjung, Burcu Vardar, Bernhard Schaefer. Worsening of kidney function in patients with atrial fibrillation and chronic kidney disease: evidence from the real-world CALLIPER study. Current medical research and opinion. 2022 Jun; 38(6):937-945. doi: 10.1080/03007995.2022.2061705. [PMID: 35392744]
  • Dan Sly, Margaret Husted, Lynn McKeague, Tamara Everington. 'I just didn't want to trust it at all': Atrial fibrillation patient's treatment experience of rivaroxaban and warfarin. Journal of evaluation in clinical practice. 2022 06; 28(3):436-444. doi: 10.1111/jep.13628. [PMID: 34636130]
  • Matthias Hoch, Tirtha Sengupta, Florence Hourcade-Potelleret. Pharmacokinetic drug interactions of asciminib with the sensitive cytochrome P450 probe substrates midazolam, warfarin, and repaglinide in healthy participants. Clinical and translational science. 2022 06; 15(6):1406-1416. doi: 10.1111/cts.13252. [PMID: 35293131]
  • Alexander T Cohen, Janvi Sah, Amol D Dhamane, Theodore Lee, Lisa Rosenblatt, Patrick Hlavacek, Birol Emir, Rachel Delinger, Huseyin Yuce, Xuemei Luo. Effectiveness and Safety of Apixaban versus Warfarin in Venous Thromboembolism Patients with Chronic Kidney Disease. Thrombosis and haemostasis. 2022 Jun; 122(6):926-938. doi: 10.1055/s-0041-1740254. [PMID: 34963185]
  • Alex Handy, Amitava Banerjee, Angela M Wood, Caroline Dale, Cathie L M Sudlow, Christopher Tomlinson, Daniel Bean, Johan H Thygesen, Mehrdad A Mizani, Michail Katsoulis, Rohan Takhar, Sam Hollings, Spiros Denaxas, Venexia Walker, Richard Dobson, Reecha Sofat. Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort. Heart (British Cardiac Society). 2022 05; 108(12):923-931. doi: 10.1136/heartjnl-2021-320325. [PMID: 35273122]
  • Jiafen Qian, Wenjun Chen, Jianmei Wu, Meina Lv, Shaojun Jiang, Zhiwei Zeng, Zongwei Fang, Mingrong Chen, Jinhua Zhang. Effects and Mechanism of Action of Panax notoginseng Saponins on the Pharmacokinetics of Warfarin. European journal of drug metabolism and pharmacokinetics. 2022 May; 47(3):331-342. doi: 10.1007/s13318-022-00753-0. [PMID: 35138605]
  • Xiaojin Liu, Quan Xiao, Yun Li, Guobing Hu, Wang Kun, Wanbo Xu. Effect of post-discharge pharmacist-led follow-up on drug treatment in patients with deep venous thrombosis in primary hospitals in China. Pakistan journal of pharmaceutical sciences. 2022 May; 35(3):785-791. doi: ". [PMID: 35791477]
  • Ophelia Yin, Tarundeep Kakkar, Anil Duggal, Masakatsu Kotsuma, Minggao Shi, Hans Lanz, Michael A Grosso. Edoxaban Exposure in Patients With Atrial Fibrillation and Estimated Creatinine Clearance Exceeding 100 mL/min. Clinical pharmacology in drug development. 2022 05; 11(5):666-674. doi: 10.1002/cpdd.1050. [PMID: 34877813]
  • Kate Traynor. Pharmacist-managed triage service guides COVID-19 antiviral treatments. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2022 04; 79(9):e99. doi: 10.1093/ajhp/zxac076. [PMID: 35325035]
  • Brittany Elgersma, Sara Zochert. Utilization of apixaban anti-Xa levels in transition from apixaban to warfarin in a patient with chronic renal dysfunction. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2022 04; 79(9):e104-e109. doi: 10.1093/ajhp/zxab469. [PMID: 34864841]
  • Eleni Alexandri, Alexandra Primikyri, Georgios Papamokos, Themistoklis Venianakis, Vasileios K Gkalpinos, Andreas G Tzakos, Andreas Karydis-Messinis, Dimitrios Moschovas, Apostolos Avgeropoulos, Ioannis P Gerothanassis. NMR and computational studies reveal novel aspects in molecular recognition of unsaturated fatty acids with non-labelled serum albumin. The FEBS journal. 2022 Apr; ?(?):. doi: 10.1111/febs.16453. [PMID: 35380736]
  • Michelle Papala, Deborah Gillard, Jennifer Hardman, Teresa Romano, Lisa E Rein. Extending INR testing intervals in warfarin patients at a multi-center anticoagulation clinic. Journal of thrombosis and thrombolysis. 2022 Apr; 53(3):626-632. doi: 10.1007/s11239-021-02566-5. [PMID: 34622376]
  • Erika Leemann Price, Jack Ansell. Virtual Education for Patient Self-Testing for Warfarin Therapy Is Effective During the COVID-19 Pandemic. Joint Commission journal on quality and patient safety. 2022 04; 48(4):214-221. doi: 10.1016/j.jcjq.2022.01.001. [PMID: 35131178]
  • Annelies De Maré, Britt Opdebeeck, Ellen Neven, Patrick C D'Haese, Anja Verhulst. Sclerostin Protects Against Vascular Calcification Development in Mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2022 04; 37(4):687-699. doi: 10.1002/jbmr.4503. [PMID: 35038187]
  • Antonio González Pérez, Yanina Balabanova, María E Sáez, Gunnar Brobert, Luis A García Rodríguez. Renal decline in patients with non-valvular atrial fibrillation treated with rivaroxaban or warfarin: A population-based study from the United Kingdom. International journal of cardiology. 2022 Apr; 352(?):165-171. doi: 10.1016/j.ijcard.2022.01.063. [PMID: 35122912]
  • Uwe Zeymer, Hendrik Bonnemeier, Christoph Wanner. [Safety and effectiveness of oral anticoagulation in patients with atrial fibrillation and renal insufficiency - a real-world perspective]. Deutsche medizinische Wochenschrift (1946). 2022 Apr; 147(10):617-624. doi: 10.1055/a-1792-7094. [PMID: 35545071]
  • Sabine Yvonne Jepsen, Julie Brogaard Larsen, Thomas Decker Christensen, Erik Lerkevang Grove, Marianne Maegaard, Anne-Mette Hvas. Warfarin monitoring and interference by lupus anticoagulant in patients with antiphospholipid syndrome. Thrombosis research. 2022 Mar; 211(?):127-132. doi: 10.1016/j.thromres.2022.01.021. [PMID: 35149398]
  • Adane Teshome Kefale, Gregory M Peterson, Woldesellassie M Bezabhe, Luke R Bereznicki. Switching of oral anticoagulants in atrial fibrillation: a cohort study using Australian general practice data. Expert review of clinical pharmacology. 2022 Mar; 15(3):351-357. doi: 10.1080/17512433.2022.2044793. [PMID: 35184624]
  • Woldesellassie M Bezabhe, Luke R Bereznicki, Jan Radford, Barbara C Wimmer, Mohammed S Salahudeen, Ivan Bindoff, Gregory M Peterson. Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants. Expert review of clinical pharmacology. 2022 Mar; 15(3):359-364. doi: 10.1080/17512433.2022.2070151. [PMID: 35452586]
  • Jason Zakko, Asvin M Ganapathi, Bryan A Whitson, Nahush A Mokadam, Matthew C Henn, Brent Lampert, Rami Kahwash, Veronica Franco, Garrie Haas, Sitaramesh Emani, Ayesha Hasan, Ajay Vallakati. Safety of direct oral anticoagulants in solid organ transplant recipients: A meta-analysis. Clinical transplantation. 2022 03; 36(3):e14513. doi: 10.1111/ctr.14513. [PMID: 34655500]
  • Masao Sekimoto, Toru Imai, Shinji Hidaka, Nobutaka Chiba, Atsushi Sakurai, Mitsumasa Hata, Norikazu Kikuchi. Elevated INR in a COVID-19 patient after concomitant administration of favipiravir and warfarin: A case report. Journal of clinical pharmacy and therapeutics. 2022 Mar; 47(3):407-410. doi: 10.1111/jcpt.13499. [PMID: 34339547]
  • Justin Chan, Kelly Michaelsen, Joanne K Estergreen, Daniel E Sabath, Shyamnath Gollakota. Micro-mechanical blood clot testing using smartphones. Nature communications. 2022 02; 13(1):831. doi: 10.1038/s41467-022-28499-y. [PMID: 35149711]
  • Emma Gee, Angeline Pol, Kwesi Kittoe, Folusho Coker, Victoria Speed. Keeping warfarin patients safe during the COVID-19 pandemic: review of an INR self-testing programme. British journal of nursing (Mark Allen Publishing). 2022 Feb; 31(3):142-146. doi: 10.12968/bjon.2022.31.3.142. [PMID: 35152746]
  • T S Shahzada, C L Guo, A P W Lee. Renal outcomes in Asian patients receiving oral anticoagulants for non-valvular atrial fibrillation. Hong Kong medical journal = Xianggang yi xue za zhi. 2022 Feb; 28(1):24-32. doi: 10.12809/hkmj209201. [PMID: 34737236]
  • Nisha Bansal, Leila R Zelnick, Kristi Reynolds, Teresa N Harrison, Ming-Sum Lee, Daniel E Singer, Sue Hee Sung, Dongjie Fan, Alan S Go. Management of Adults with Newly Diagnosed Atrial Fibrillation with and without CKD. Journal of the American Society of Nephrology : JASN. 2022 02; 33(2):442-453. doi: 10.1681/asn.2021060744. [PMID: 34921110]
  • Gaurav Bhandari, Vaibhav Tiwari, Anurag Gupta, Pallav Gupta, Vinant Bhargava, Manish Malik, Ashwani Gupta, Anil Kumar Bhalla, D S Rana. Double whammy: anticoagulant-related nephropathy with leukocytoclastic vasculitis due to warfarin. CEN case reports. 2022 02; 11(1):154-158. doi: 10.1007/s13730-021-00642-6. [PMID: 34533696]
  • Izabela Zakrocka, Wojciech Załuska. Anticoagulant-related nephropathy: Focus on novel agents. A review. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 2022 Feb; 31(2):165-173. doi: 10.17219/acem/142657. [PMID: 35212199]
  • Lujing Wang, Yang Chen, Wangda Zhou, Xin Miao, Honghui Zhou. Utilization of physiologically-based pharmacokinetic model to assess disease-mediated therapeutic protein-disease-drug interaction in immune-mediated inflammatory diseases. Clinical and translational science. 2022 02; 15(2):464-476. doi: 10.1111/cts.13164. [PMID: 34581012]
  • Xiaoan Li, Tiantian Guo, Qian Feng, Tiantian Bai, Lei Wu, Yubo Liu, Xu Zheng, Jianzhong Jia, Jin Pei, Shaoping Wu, Yiming Song, Yongmin Zhang. Progress of thrombus formation and research on the structure-activity relationship for antithrombotic drugs. European journal of medicinal chemistry. 2022 Jan; 228(?):114035. doi: 10.1016/j.ejmech.2021.114035. [PMID: 34902735]
  • Waimei Amy Tai. Stroke: Primary Prevention. FP essentials. 2022 Jan; 512(?):11-17. doi: NULL. [PMID: 35006660]
  • Koji Nishi, Ayana Yano, Kenji Tsukigawa, Victor Tg Chuang, Masaki Otagiri, Keishi Yamasaki. Effect of Fatty Acids and Uremic Toxins on the Binding of Nateglinide, an Insulin Secretagogue, to Site II on Human Serum Albumin. Biological & pharmaceutical bulletin. 2022; 45(6):803-805. doi: 10.1248/bpb.b22-00116. [PMID: 35650107]
  • Kin Wah Fung, Seo H Baik, Fitsum Baye, Zhaonian Zheng, Vojtech Huser, Clement J McDonald. Effect of common maintenance drugs on the risk and severity of COVID-19 in elderly patients. PloS one. 2022; 17(4):e0266922. doi: 10.1371/journal.pone.0266922. [PMID: 35436293]
  • Rita Guzzi, Rosa Bartucci. Interactive multiple binding of oleic acid, warfarin and ibuprofen with human serum albumin revealed by thermal and fluorescence studies. European biophysics journal : EBJ. 2022 Jan; 51(1):41-49. doi: 10.1007/s00249-021-01582-w. [PMID: 35048131]
  • Fang Ma, Li Yuan, Xinli Wen, Yangyang Wang, Qiaofei Li, Chu Chen. Efficacy and Safety of Direct Oral Anticoagulants in Stable Coronary Artery Disease and Atrial Fibrillation: A Systematic Review and Network Meta-Analysis. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 2022 Jan; 28(?):10760296221131033. doi: 10.1177/10760296221131033. [PMID: 36198012]
  • John Sy, Cachet Wenziger, Maria Marroquin, Kamyar Kalantar-Zadeh, Csaba Kovesdy, Elani Streja. Warfarin Use, Stroke, and Bleeding Risk among Pre-Existing Atrial Fibrillation US Veterans Transitioning to Dialysis. Nephron. 2022; 146(4):360-368. doi: 10.1159/000521494. [PMID: 35124673]
  • Sarudzai Muyambo, Arinao Ndadza, Nyarai D Soko, Bianca Kruger, Gerard Kadzirange, Emile Chimusa, Collen M Masimirembwa, Mpiko Ntsekhe, Charles F B Nhachi, Collet Dandara. Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes. Omics : a journal of integrative biology. 2022 01; 26(1):35-50. doi: 10.1089/omi.2021.0199. [PMID: 34958284]
  • Mindi Zhao, Xiaoyan Liu, Xiaoxiao Bu, Yao Li, Meng Wang, Bo Zhang, Wei Sun, Chuanbao Li. Application of plasma metabolome for monitoring the effect of rivaroxaban in patients with nonvalvular atrial fibrillation. PeerJ. 2022; 10(?):e13853. doi: 10.7717/peerj.13853. [PMID: 35966924]
  • Inmaculada Hernandez, Nico Gabriel, Meiqi He, Jingchuan Guo, Mina Tadrous, Katie J Suda, Jared W Magnani. COVID-19 and Anticoagulation for Atrial Fibrillation: An Analysis of US Nationwide Pharmacy Claims Data. Journal of the American Heart Association. 2021 12; 10(24):e023235. doi: 10.1161/jaha.121.023235. [PMID: 34913359]
  • Luca Di Lullo, Carlo Lavalle, Michele Magnocavallo, Marco Valerio Mariani, Domenico Giovanni Della Rocca, Paolo Severino, Biagio Raffaele Di Iorio, Domenico Russo, Francesco Summaria, Giovanni Battista Forleo, Claudio Ronco, Massimo Mancone, Cristina Chimenti, Fabio Miraldi, Andrea Natale, Antonio Bellasi. New evidence of direct oral anticoagulation therapy on cardiac valve calcifications, renal preservation and inflammatory modulation. International journal of cardiology. 2021 Dec; 345(?):90-97. doi: 10.1016/j.ijcard.2021.10.025. [PMID: 34688719]
  • Sazia Iftekhar, David S Hage. Evaluation of microcolumn stability in ultrafast affinity extraction for binding and rate studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2021 Dec; 1187(?):123047. doi: 10.1016/j.jchromb.2021.123047. [PMID: 34823097]
  • Neema Jamshidi, Weiyi Tan, Dingle Foote, Leigh Reardon, Gentian Lluri, Jamil Aboulhosn, John Moriarty, Jeannette Lin. Mechanical thrombectomy of COVID-19 DVT with congenital heart disease leading to phlegmasia cerulea dolens: a case report. BMC cardiovascular disorders. 2021 12; 21(1):592. doi: 10.1186/s12872-021-02403-w. [PMID: 34886795]
  • Akira Kondo, Hirokazu Kondo, Yoshihisa Nakagawa, Hideki Kameyama, Hiroyuki Ito, Daiki Shimomura, Hachiro Yamanishi, Noriko Hatanaka, Yoshikazu Yamamoto, Eri Iwai-Kanai, Shuji Matsuo. Measuring serum prothrombin in patients treated with warfarin or direct oral anticoagulants. Clinica chimica acta; international journal of clinical chemistry. 2021 Dec; 523(?):224-230. doi: 10.1016/j.cca.2021.09.023. [PMID: 34599901]
  • Chen-Yen Lu, Po-Chun Tseng, Kuan-Chih Chen, Chun-Chieh Huang, Yuk-Ming Tsang, Tzong-His Lee, Cheng-Kuan Lin, Chen-Shuan Chung. Case 296: Phlebosclerotic Colitis. Radiology. 2021 12; 301(3):735-740. doi: 10.1148/radiol.2021201802. [PMID: 34807772]
  • Taofik Rusdiana, Yanni D Mardhiani, Norisca A Putriana, Dolih Gozali, Daisuke Nagano, Takuya Araki, Koujirou Yamamoto. The influence of Javanese turmeric (Curcuma xanthorrhiza) on the pharmacokinetics of warfarin in rats with single and multiple-dose studies. Pharmaceutical biology. 2021 Dec; 59(1):639-646. doi: 10.1080/13880209.2021.1928716. [PMID: 34062109]
  • Chen Gurevitz, Ela Giladi, Alon Barsheshet, Robert Klempfner, Ilan Goldenberg, Ran Kornowski, Avishay Elis. Comparison of Low and Full Dose Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Renal Dysfunction (from a National Registry). The American journal of cardiology. 2021 11; 159(?):87-93. doi: 10.1016/j.amjcard.2021.08.022. [PMID: 34503821]
  • Mohamad Mahani, Moazame Kordi. Warfarin Induced Quenching of the Carbon Quantum Dots: Mechanism Study and Warfarin Sensor Construction. Journal of fluorescence. 2021 Nov; 31(6):1731-1738. doi: 10.1007/s10895-021-02804-2. [PMID: 34460043]
  • Helen J Curtis, Brian MacKenna, Alex J Walker, Richard Croker, Amir Mehrkar, Caroline Morton, Seb Bacon, George Hickman, Peter Inglesby, Chris Bates, David Evans, Tom Ward, Jonathan Cockburn, Simon Davy, Krishnan Bhaskaran, Anna Schultze, Christopher T Rentsch, Elizabeth Williamson, William Hulme, Laurie Tomlinson, Rohini Mathur, Henry Drysdale, Rosalind M Eggo, Angel Yun Wong, Harriet Forbes, John Parry, Frank Hester, Sam Harper, Ian Douglas, Liam Smeeth, Ben Goldacre. OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic. Open heart. 2021 11; 8(2):. doi: 10.1136/openhrt-2021-001784. [PMID: 34785588]
  • Paula Mendonça Leite, Maria Auxiliadora Parreiras Martins, Maria das Graças Carvalho, Rachel Oliveira Castilho. Mechanisms and interactions in concomitant use of herbs and warfarin therapy: An updated review. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Nov; 143(?):112103. doi: 10.1016/j.biopha.2021.112103. [PMID: 34474338]
  • Angel Y S Wong, Laurie A Tomlinson, Jeremy P Brown, William Elson, Alex J Walker, Anna Schultze, Caroline E Morton, David Evans, Peter Inglesby, Brian MacKenna, Krishnan Bhaskaran, Christopher T Rentsch, Emma Powell, Elizabeth Williamson, Richard Croker, Seb Bacon, William Hulme, Chris Bates, Helen J Curtis, Amir Mehrkar, Jonathan Cockburn, Helen I McDonald, Rohini Mathur, Kevin Wing, Harriet Forbes, Rosalind M Eggo, Stephen J W Evans, Liam Smeeth, Ben Goldacre, Ian J Douglas. Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study. Journal of hematology & oncology. 2021 10; 14(1):172. doi: 10.1186/s13045-021-01185-0. [PMID: 34666811]
  • Arun Prabhahar Rajarajen, Raihan Ashraf, Nishtha Ahuja, Joyita Bharati. Extensive skin necrosis in an elderly woman on dabigatran. BMJ case reports. 2021 Oct; 14(10):. doi: 10.1136/bcr-2021-245245. [PMID: 34649859]
  • Cina Sasannejad, Kevin N Sheth. Anticoagulation in Acute Neurological Disease. Seminars in neurology. 2021 10; 41(5):530-540. doi: 10.1055/s-0041-1733793. [PMID: 34619779]
  • Ziv Harel, Eric McArthur, Nivethika Jeyakumar, Manish M Sood, Amit X Garg, Samuel A Silver, Paul Dorian, Daniel Blum, William Beaubien-Souligny, Andrew T Yan, Sunil V Badve, Brendan Smyth, Min Jun, Racquel Jandoc, Abhijat Kitchlu, Ron Wald. The Risk of Acute Kidney Injury with Oral Anticoagulants in Elderly Adults with Atrial Fibrillation. Clinical journal of the American Society of Nephrology : CJASN. 2021 10; 16(10):1470-1479. doi: 10.2215/cjn.05920421. [PMID: 34407990]
  • Colleen K Gabel, Emily D Nguyen, Teja Chakrala, Amy E Blum, Josie François, Sidharth Chand, Renajd Rrapi, Olesya Baker, Allison S Dobry, Anna Cristina Garza-Mayers, Lauren N Ko, Radhika Shah, Jessica St John, Sagar U Nigwekar, Daniela Kroshinsky. Assessment of outcomes of calciphylaxis. Journal of the American Academy of Dermatology. 2021 10; 85(4):1057-1064. doi: 10.1016/j.jaad.2020.10.067. [PMID: 33130181]
  • Lai-Chu See, Hsin-Fu Lee, Tze-Fan Chao, Pei-Ru Li, Jia-Rou Liu, Lung-Sheng Wu, Shang-Hung Chang, Yung-Hsin Yeh, Chi-Tai Kuo, Yi-Hsin Chan, Gregory Y H Lip. Effectiveness and Safety of Direct Oral Anticoagulants in an Asian Population with Atrial Fibrillation Undergoing Dialysis: A Population-Based Cohort Study and Meta-Analysis. Cardiovascular drugs and therapy. 2021 10; 35(5):975-986. doi: 10.1007/s10557-020-07108-4. [PMID: 33211254]
  • Rebecca Cope, Briann Fischetti, Nourhan Eladghm, Mahy Elaskandrany, Nardine Karam. Outpatient management of chronic warfarin therapy at a pharmacist-run anticoagulation clinic during the COVID-19 pandemic. Journal of thrombosis and thrombolysis. 2021 Oct; 52(3):754-758. doi: 10.1007/s11239-021-02410-w. [PMID: 33677744]
  • Zlatko Pravdic, Mirjana Mitrovic, Andrija Bogdanovic, Marijana Virijevic, Nikica Sabljic, Nikola Pantic, Nada Suvajdzic Vukovic. COVID-19 Presented with Deep Vein Thrombosis in a Patient with Paroxysmal Nocturnal Haemoglobinuria. Hamostaseologie. 2021 Oct; 41(5):397-399. doi: 10.1055/a-1554-6432. [PMID: 34544179]
  • Xinying Wang, Guangyuan Zhang, Di Yu, Ning Wang, Qingxiang Guan. The interaction of folate-modified Bletilla striata polysaccharide-based micelle with bovine serum albumin. Glycoconjugate journal. 2021 10; 38(5):585-597. doi: 10.1007/s10719-021-10022-y. [PMID: 34586534]
  • Sho Shiroma, Waku Hatta, Yosuke Tsuji, Toshiyuki Yoshio, Yohei Yabuuchi, Shu Hoteya, Shigetsugu Tsuji, Yasuaki Nagami, Takuto Hikichi, Masakuni Kobayashi, Yoshinori Morita, Tetsuya Sumiyoshi, Mikitaka Iguchi, Hideomi Tomida, Takuya Inoue, Tatsuya Mikami, Kenkei Hasatani, Jun Nishikawa, Tomoaki Matsumura, Hiroko Nebiki, Dai Nakamatsu, Ken Ohnita, Haruhisa Suzuki, Hiroya Ueyama, Yoshito Hayashi, Mitsushige Sugimoto, Shinjiro Yamaguchi, Tomoki Michida, Tomoyuki Yada, Yoshiro Asahina, Toshiaki Narasaka, Shiko Kuribayashi, Shu Kiyotoki, Katsuhiro Mabe, Mitsuhiro Fujishiro, Atsushi Masamune, Junko Fujisaki. Timing of bleeding and thromboembolism associated with endoscopic submucosal dissection for gastric cancer in Japan. Journal of gastroenterology and hepatology. 2021 Oct; 36(10):2769-2777. doi: 10.1111/jgh.15536. [PMID: 33960518]
  • Luisa Weiss, John Keaney, Paulina B Szklanna, Tadhg Prendiville, Wido Uhrig, Kieran Wynne, Sarah Kelliher, Karl Ewins, Shane P Comer, Karl Egan, Ellen O'Rourke, Eric Moran, Georgi Petrov, Ashish Patel, Áine Lennon, Alfonso Blanco, Barry Kevane, Sean Murphy, Fionnuala Ní Áinle, Patricia B Maguire. Nonvalvular atrial fibrillation patients anticoagulated with rivaroxaban compared with warfarin exhibit reduced circulating extracellular vesicles with attenuated pro-inflammatory protein signatures. Journal of thrombosis and haemostasis : JTH. 2021 10; 19(10):2583-2595. doi: 10.1111/jth.15434. [PMID: 34161660]
  • Jose C Alonso-Escalante, Lorenzo Machado, Kiumars R Tabar, Rachell Tindall, Ngoc Thai, Tadahiro Uemura. Is Continuing Anticoagulation or Antiplatelet Therapy Safe Prior to Kidney Transplantation?. Annals of transplantation. 2021 Sep; 26(?):e931648. doi: 10.12659/aot.931648. [PMID: 34580271]
  • Tomotaka Tanaka, Masafumi Ihara, Kazuki Fukuma, Haruko Yamamoto, Kazuo Washida, Shunsuke Kimura, Akiko Kada, Shigeki Miyata, Toshiyuki Miyata, Kazuyuki Nagatsuka. Influence of Renal Impairment and Genetic Subtypes on Warfarin Control in Japanese Patients. Genes. 2021 09; 12(10):. doi: 10.3390/genes12101537. [PMID: 34680932]
  • Chung-Ping Yu, Meng-Syuan Yang, Pei-Wen Hsu, Shiuan-Pey Lin, Yu-Chi Hou. Bidirectional Influences of Cranberry on the Pharmacokinetics and Pharmacodynamics of Warfarin with Mechanism Elucidation. Nutrients. 2021 Sep; 13(9):. doi: 10.3390/nu13093219. [PMID: 34579096]
  • Jun Haginaka, Arisa Kubo, Tetsutaro Kimachi, Yusuke Kobayashi. Retention and molecular-recognition mechanisms of molecularly imprinted polymers for warfarin derivatives and their application for the determination of warfarin in human serum. Talanta. 2021 Sep; 232(?):122419. doi: 10.1016/j.talanta.2021.122419. [PMID: 34074406]
  • Thoranis Chantrarat, Rungroj Krittayaphong. The Clinical Outcomes of Different eGFR Strata and Time in Therapeutic Range in Atrial Fibrillation Patients with Chronic Kidney Disease: A Nationwide Cohort Study. Current problems in cardiology. 2021 Sep; 46(9):100838. doi: 10.1016/j.cpcardiol.2021.100838. [PMID: 33992427]
  • Hafez M Abdullah, Waqas Ullah, Munnam Sohail Jafar, Martin van Zyl, Rehan Saeed, Mahboob Alam, M Chadi Alraies, David L Fischman. Safety and Efficacy of Apixaban, Rivaroxaban, and Warfarin in End-Stage Renal Disease With Atrial Fibrillation: A Systematic Review and Meta-Analysis. Cardiovascular revascularization medicine : including molecular interventions. 2021 09; 30(?):26-32. doi: 10.1016/j.carrev.2020.09.041. [PMID: 34420589]
  • Alethea Charlton, Xavier Vidal, Mònica Sabaté, Elena Bailarín, Lina María Leguízamo Martínez, Luisa Ibáñez. Factors associated with primary nonadherence to newly initiated direct oral anticoagulants in patients with nonvalvular atrial fibrillation. Journal of managed care & specialty pharmacy. 2021 Sep; 27(9):1210-1220. doi: 10.18553/jmcp.2021.27.9.1210. [PMID: 34464214]
  • Olivia S Costa, Bridget O'Donnell, Burcu Vardar, Khaled Abdelgawwad, Christopher W Brescia, Nitesh Sood, Craig I Coleman. Kidney, limb and ophthalmic complications, and death in patients with nonvalvular atrial fibrillation and type 2 diabetes prescribed rivaroxaban or warfarin: an electronic health record analysis. Current medical research and opinion. 2021 09; 37(9):1493-1500. doi: 10.1080/03007995.2021.1947217. [PMID: 34166150]
  • Kendra Lys Calixto Machado, Suzana Tanquella da Rosa, Soraya Dobner, Ivan Schneider Boettcher, Gilberto Comaru Pasqualotto, Adelina Elisabeth Lehmkuhl Lopes, Tainá de Araújo, Lysandra Patricia Luchtenberg Bolduan, Maria Daniela Holthausen Perico Colombo, Marcelo Pitombeira de Lacerda. Warfarin anticoagulation in the Covid-19 pandemic: Telephone-based management at a regional hematology outpatient center in Joinville, Brazil. Thrombosis research. 2021 09; 205(?):81-83. doi: 10.1016/j.thromres.2021.07.006. [PMID: 34265606]
  • Jing Liu, Cuiying Liu, Chunqi Qian, George Abela, Wei Sun, Xiangqing Kong. Ginkgo Biloba Extract EGB761 Alleviates Warfarin-induced Aortic Valve Calcification Through the BMP2/Smad1/5/Runx2 Signaling Pathway. Journal of cardiovascular pharmacology. 2021 09; 78(3):411-421. doi: 10.1097/fjc.0000000000001082. [PMID: 34132687]
  • Kazuo Kitagawa. [Anti-Platelet and Anti-Coagulant Drugs]. Brain and nerve = Shinkei kenkyu no shinpo. 2021 Sep; 73(9):975-982. doi: 10.11477/mf.1416201874. [PMID: 34462368]
  • Lei Chen, Yang-Zhao Zhou, Xin-Min Zhou, Li-Ming Liu, Ping Xu, Xia Zhang, Sheng-Lan Tan. Evaluation of the 'safe multidisciplinary app-assisted remote patient-self-testing (SMART) model' for warfarin home management during the COVID-19 pandemic: study protocol of a multi-center randomized controlled trial. BMC health services research. 2021 Aug; 21(1):875. doi: 10.1186/s12913-021-06882-7. [PMID: 34445995]
  • Matthew W Sherwood, Sean D Pokorney. Getting (Left Atrial Appendage) Closure With Kidney Disease. JACC. Cardiovascular interventions. 2021 08; 14(16):1840-1842. doi: 10.1016/j.jcin.2021.07.009. [PMID: 34412802]
  • Hamid Reza Kalhor, Elham Taghikhani. Probe into the Molecular Mechanism of Ibuprofen Interaction with Warfarin Bound to Human Serum Albumin in Comparison to Ascorbic and Salicylic Acids: Allosteric Inhibition of Anticoagulant Release. Journal of chemical information and modeling. 2021 08; 61(8):4045-4057. doi: 10.1021/acs.jcim.1c00352. [PMID: 34292735]
  • Jawad H Butt, Emil L Fosbøl, Peter Verhamme, Thomas A Gerds, Kasper Iversen, Henning Bundgaard, Niels Eske Bruun, Anders R Larsen, Andreas Petersen, Paal S Andersen, Robert L Skov, Gunnar H Gislason, Christian Torp-Pedersen, Lars Køber, Jonas B Olesen. Dabigatran and the Risk of Staphylococcus aureus Bacteremia: A Nationwide Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 08; 73(3):480-486. doi: 10.1093/cid/ciaa661. [PMID: 32478836]
  • Gregory Y H Lip, Allison V Keshishian, Yan Zhang, Amiee Kang, Amol D Dhamane, Xuemei Luo, Christian Klem, Mauricio Ferri, Jenny Jiang, Huseyin Yuce, Steven Deitelzweig. Oral Anticoagulants for Nonvalvular Atrial Fibrillation in Patients With High Risk of Gastrointestinal Bleeding. JAMA network open. 2021 08; 4(8):e2120064. doi: 10.1001/jamanetworkopen.2021.20064. [PMID: 34398204]
  • James B Wetmore, Heng Yan, Charles A Herzog, Eric Weinhandl, Jorge L Reyes, Nicholas S Roetker. CKD Progression in Medicare Beneficiaries With Nonvalvular Atrial Fibrillation Treated With Apixaban Versus Warfarin. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2021 08; 78(2):180-189. doi: 10.1053/j.ajkd.2020.12.004. [PMID: 33421454]
  • Harrison Faulkner, Shubham Chakankar, Marco Mammi, Jack Yu Tung Lo, Joanne Doucette, Nawaf Al-Otaibi, Judi Abboud, Andrew Le, Rania A Mekary, Adomas Bunevicius. Safety and efficacy of prothrombin complex concentrate (PCC) for anticoagulation reversal in patients undergoing urgent neurosurgical procedures: a systematic review and metaanalysis. Neurosurgical review. 2021 Aug; 44(4):1921-1931. doi: 10.1007/s10143-020-01406-z. [PMID: 33009989]
  • Tomomi Nakajima, Yuki Taya, Takanobu Nishikawa, Yutaka Kitamura, Hideyuki Kato, Bryan J Mathis, Yuji Hiramatsu. First Clinical Trial of a Newly Developed, Low Menaquinone-7, Fermented Soybean Natto in Warfarin-Dependent Patients. Journal of medicinal food. 2021 Aug; 24(8):860-865. doi: 10.1089/jmf.2021.0036. [PMID: 34406879]