DL-Glutamine (BioDeep_00000014696)

   

PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


DL-Glutamine

化学式: C5H10N2O3 (146.069139)
中文名称: DL-谷氨酰胺, 谷氨酰胺
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 2.94%

分子结构信息

SMILES: C(CC(=O)N)C(C(=O)O)N
InChI: InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)

描述信息

DL-Glutamine is used for biochemical research and drug synthesis.

同义名列表

3 个代谢物同义名

DL-Glutamine; (±)-Glutamine; DL-Gl



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Victoria R Richardson, Paul Cordell, Kristina F Standeven, Angela M Carter. Substrates of Factor XIII-A: roles in thrombosis and wound healing. Clinical science (London, England : 1979). 2013 Feb; 124(3):123-37. doi: 10.1042/cs20120233. [PMID: 23075332]
  • C C Taylor-Edwards, D G Burrin, N B Kristensen, J J Holst, K R McLeod, D L Harmon. Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves. Animal : an international journal of animal bioscience. 2012 Dec; 6(12):1985-97. doi: 10.1017/s175173111200095x. [PMID: 23031436]
  • Jelena Kolarevic, Harald Takle, Olga Felip, Elisabeth Ytteborg, Roger Selset, Christopher M Good, Grete Baeverfjord, Torbjørn Asgård, Bendik Fyhn Terjesen. Molecular and physiological responses to long-term sublethal ammonia exposure in Atlantic salmon (Salmo salar). Aquatic toxicology (Amsterdam, Netherlands). 2012 Nov; 124-125(?):48-57. doi: 10.1016/j.aquatox.2012.07.003. [PMID: 22898234]
  • Tai-Sheng Cheng. The toxic effects of diethyl phthalate on the activity of glutamine synthetase in greater duckweed (Spirodela polyrhiza L.). Aquatic toxicology (Amsterdam, Netherlands). 2012 Nov; 124-125(?):171-8. doi: 10.1016/j.aquatox.2012.08.014. [PMID: 22975440]
  • Sandesh C S Nagamani, Oleg A Shchelochkov, Mary A Mullins, Susan Carter, Brendan C Lanpher, Qin Sun, Soledad Kleppe, Ayelet Erez, E O'Brian Smith, Juan C Marini, Brendan Lee. A randomized controlled trial to evaluate the effects of high-dose versus low-dose of arginine therapy on hepatic function tests in argininosuccinic aciduria. Molecular genetics and metabolism. 2012 Nov; 107(3):315-21. doi: 10.1016/j.ymgme.2012.09.016. [PMID: 23040521]
  • Shunli Wang, Xixi Shen, Pei Ge, Jie Li, Saminathan Subburaj, Xiaohui Li, F J Zeller, S L K Hsam, Yueming Yan. Molecular characterization and dynamic expression patterns of two types of γ-gliadin genes from Aegilops and Triticum species. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2012 Nov; 125(7):1371-84. doi: 10.1007/s00122-012-1917-4. [PMID: 22751951]
  • Anshu Srivastava, Santosh K Yadav, Vibhor V Borkar, Abhishek Yadav, Surender K Yachha, Michael A Thomas, Ram K S Rathore, Chandra M Pandey, Rakesh K Gupta. Serial evaluation of children with ALF with advanced MRI, serum proinflammatory cytokines, thiamine, and cognition assessment. Journal of pediatric gastroenterology and nutrition. 2012 Nov; 55(5):580-6. doi: 10.1097/mpg.0b013e31825f4c3e. [PMID: 22614112]
  • Anusha K S Dhanasiri, Jorge M O Fernandes, Viswanath Kiron. Glutamine synthetase activity and the expression of three glul paralogues in zebrafish during transport. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2012 Nov; 163(3-4):274-84. doi: 10.1016/j.cbpb.2012.06.003. [PMID: 22750401]
  • Richard C Waterman, Valerie L Ujazdowski, Mark K Petersen. Effects of rumen-protected methionine on plasma amino acid concentrations during a period of weight loss for late gestating beef heifers. Amino acids. 2012 Nov; 43(5):2165-77. doi: 10.1007/s00726-012-1301-3. [PMID: 22555648]
  • Maria M Adeva, Gema Souto, Natalia Blanco, Cristóbal Donapetry. Ammonium metabolism in humans. Metabolism: clinical and experimental. 2012 Nov; 61(11):1495-511. doi: 10.1016/j.metabol.2012.07.007. [PMID: 22921946]
  • Baljit K Ubhi, Kian Kai Cheng, Jiyang Dong, Tobias Janowitz, Duncan Jodrell, Ruth Tal-Singer, William MacNee, David A Lomas, John H Riley, Julian L Griffin, Susan C Connor. Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Molecular bioSystems. 2012 Oct; 8(12):3125-33. doi: 10.1039/c2mb25194a. [PMID: 23051772]
  • Bin Xu, Zhao-Fa Xu, Yu Deng, Wei Liu, Hai-Bo Yang, Yan-Gang Wei. Protective effects of MK-801 on methylmercury-induced neuronal injury in rat cerebral cortex: involvement of oxidative stress and glutamate metabolism dysfunction. Toxicology. 2012 Oct; 300(3):112-20. doi: 10.1016/j.tox.2012.06.006. [PMID: 22722016]
  • Wenyu Liang, Youwen Zhou, Lingxia Wang, Xiangrong You, Yaping Zhang, Chi-Lien Cheng, Wei Chen. Ultrastructural, physiological and proteomic analysis of Nostoc flagelliforme in response to dehydration and rehydration. Journal of proteomics. 2012 Oct; 75(18):5604-27. doi: 10.1016/j.jprot.2012.07.041. [PMID: 22884584]
  • Soumita Ghosh, Arjun Sengupta, Shobhona Sharma, Haripalsingh M Sonawat. Metabolic fingerprints of serum, brain, and liver are distinct for mice with cerebral and noncerebral malaria: a ¹H NMR spectroscopy-based metabonomic study. Journal of proteome research. 2012 Oct; 11(10):4992-5004. doi: 10.1021/pr300562m. [PMID: 22838963]
  • Nicolas Poirier, Natacha Roudnitzky, Anne Brockhoff, Christine Belloir, Marie Maison, Thierry Thomas-Danguin, Wolfgang Meyerhof, Loïc Briand. Efficient production and characterization of the sweet-tasting brazzein secreted by the yeast Pichia pastoris. Journal of agricultural and food chemistry. 2012 Oct; 60(39):9807-14. doi: 10.1021/jf301600m. [PMID: 22958103]
  • Timothy A Wencewicz, Christopher T Walsh. Pseudomonas syringae self-protection from tabtoxinine-β-lactam by ligase TblF and acetylase Ttr. Biochemistry. 2012 Oct; 51(39):7712-25. doi: 10.1021/bi3011384. [PMID: 22994681]
  • Qin Yu, Lian Sun, Haihong Jin, Qian Chen, Zunwei Chen, Maojun Xu. Lead-induced nitric oxide generation plays a critical role in lead uptake by Pogonatherum crinitum root cells. Plant & cell physiology. 2012 Oct; 53(10):1728-36. doi: 10.1093/pcp/pcs116. [PMID: 22904111]
  • Isaac Marin-Valencia, Levi B Good, Qian Ma, Joao Duarte, Teodoro Bottiglieri, Christopher M Sinton, Charles W Heilig, Juan M Pascual. Glut1 deficiency (G1D): epilepsy and metabolic dysfunction in a mouse model of the most common human phenotype. Neurobiology of disease. 2012 Oct; 48(1):92-101. doi: 10.1016/j.nbd.2012.04.011. [PMID: 22683290]
  • Peter Nissen Bjerring, John Hauerberg, Hans-Jørgen Frederiksen, Henning Bay Nielsen, Jens Otto Clemmesen, Fin Stolze Larsen. The effect of fractionated plasma separation and adsorption on cerebral amino acid metabolism and oxidative metabolism during acute liver failure. Journal of hepatology. 2012 Oct; 57(4):774-9. doi: 10.1016/j.jhep.2012.06.004. [PMID: 22691571]
  • Xiang Zhong, Wei Li, Xuexin Huang, Yuanxiao Wang, Lili Zhang, Yanmin Zhou, Ahmad Hussain, Tian Wang. Effects of glutamine supplementation on the immune status in weaning piglets with intrauterine growth retardation. Archives of animal nutrition. 2012 Oct; 66(5):347-56. doi: 10.1080/1745039x.2012.683325. [PMID: 22962945]
  • Laura Ciarlo, Valeria Manganelli, Paola Matarrese, Tina Garofalo, Antonella Tinari, Lucrezia Gambardella, Matteo Marconi, Maria Grasso, Roberta Misasi, Maurizio Sorice, Walter Malorni. Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease. Journal of lipid research. 2012 Oct; 53(10):2057-2068. doi: 10.1194/jlr.m026062. [PMID: 22773688]
  • Xiang-ying Kong, Rong-tian Wang, Neng Tian, Li Li, Na Lin, Wei-heng Chen. Effect of Huogu II Formula (II) with medicinal guide Radix Achyranthis Bidentatae on bone marrow stem cells directional homing to necrosis area after osteonecrosis of the femoral head in rabbit. Chinese journal of integrative medicine. 2012 Oct; 18(10):761-8. doi: 10.1007/s11655-011-0940-7. [PMID: 22241502]
  • Rekha Chawla, Roshani Shakya, Caius M Rommens. Tuber-specific silencing of asparagine synthetase-1 reduces the acrylamide-forming potential of potatoes grown in the field without affecting tuber shape and yield. Plant biotechnology journal. 2012 Oct; 10(8):913-24. doi: 10.1111/j.1467-7652.2012.00720.x. [PMID: 22726556]
  • S Rossini Oliva, M D Mingorance, E O Leidi. Tolerance to high Zn in the metallophyte Erica andevalensis Cabezudo & Rivera. Ecotoxicology (London, England). 2012 Oct; 21(7):2012-21. doi: 10.1007/s10646-012-0953-9. [PMID: 22678555]
  • Marcus Borgenvik, Marie Nordin, C Mikael Mattsson, Jonas K Enqvist, Eva Blomstrand, Björn Ekblom. Alterations in amino acid concentrations in the plasma and muscle in human subjects during 24 h of simulated adventure racing. European journal of applied physiology. 2012 Oct; 112(10):3679-88. doi: 10.1007/s00421-012-2350-8. [PMID: 22350359]
  • Sherif Awad, Francis Stephens, Chris Shannon, Dileep N Lobo. Perioperative perturbations in carnitine metabolism are attenuated by preoperative carbohydrate treatment: Another mechanism by which preoperative feeding may attenuate development of postoperative insulin resistance. Clinical nutrition (Edinburgh, Scotland). 2012 Oct; 31(5):717-20. doi: 10.1016/j.clnu.2012.02.015. [PMID: 22444237]
  • Jing Zhao, Jing Chen, Haining Zhu, Youling L Xiong. Mass spectrometric evidence of malonaldehyde and 4-hydroxynonenal adductions to radical-scavenging soy peptides. Journal of agricultural and food chemistry. 2012 Sep; 60(38):9727-36. doi: 10.1021/jf3026277. [PMID: 22946674]
  • Alexandra Baar, Sandra Pahr, Claudia Constantin, Sandra Scheiblhofer, Josef Thalhamer, Stavroula Giavi, Nikolaos G Papadopoulos, Christof Ebner, Adriano Mari, Susanne Vrtala, Rudolf Valenta. Molecular and immunological characterization of Tri a 36, a low molecular weight glutenin, as a novel major wheat food allergen. Journal of immunology (Baltimore, Md. : 1950). 2012 Sep; 189(6):3018-25. doi: 10.4049/jimmunol.1200438. [PMID: 22904302]
  • Heather D Coleman, Francisco M Cánovas, Huimin Man, Edward G Kirby, Shawn D Mansfield. Enhanced expression of glutamine synthetase (GS1a) confers altered fibre and wood chemistry in field grown hybrid poplar (Populus tremula X alba) (717-1B4). Plant biotechnology journal. 2012 Sep; 10(7):883-9. doi: 10.1111/j.1467-7652.2012.00714.x. [PMID: 22672155]
  • P R Santos-Filho, S C Vitor, L Frungillo, E E Saviani, H C Oliveira, I Salgado. Nitrate reductase- and nitric oxide-dependent activation of sinapoylglucose:malate sinapoyltransferase in leaves of Arabidopsis thaliana. Plant & cell physiology. 2012 Sep; 53(9):1607-16. doi: 10.1093/pcp/pcs104. [PMID: 22833666]
  • Abu Hena Mostafa Kamal, Kun Cho, Da-Eun Kim, Nobuyuki Uozumi, Keun-Yook Chung, Sang Young Lee, Jong-Soon Choi, Seong-Woo Cho, Chang-Seob Shin, Sun Hee Woo. Changes in physiology and protein abundance in salt-stressed wheat chloroplasts. Molecular biology reports. 2012 Sep; 39(9):9059-74. doi: 10.1007/s11033-012-1777-7. [PMID: 22736107]
  • Xuemin Wang, Ying Xue, Menfan Liang, Wei Jiang. Glutamine treatment decreases plasma and lymph cytotoxicity during sepsis in rats. Acta biochimica et biophysica Sinica. 2012 Sep; 44(9):774-82. doi: 10.1093/abbs/gms054. [PMID: 22782141]
  • Christian Gegenbauer, Veronika E Mayer, Gerhard Zotz, Andreas Richter. Uptake of ant-derived nitrogen in the myrmecophytic orchid Caularthron bilamellatum. Annals of botany. 2012 Sep; 110(4):757-66. doi: 10.1093/aob/mcs140. [PMID: 22778148]
  • Arthur J L Cooper, Boris F Krasnikov, John T Pinto, Hank F Kung, Jianyong Li, Karl Ploessl. Comparative enzymology of (2S,4R)4-fluoroglutamine and (2S,4R)4-fluoroglutamate. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2012 Sep; 163(1):108-20. doi: 10.1016/j.cbpb.2012.05.010. [PMID: 22613816]
  • Lin Zhang, Haifeng Jin, Xuegang Guo, Zhao Yang, Lina Zhao, Shanhong Tang, Ping Mo, Kaichun Wu, Yongzhan Nie, Yanglin Pan, Daiming Fan. Distinguishing pancreatic cancer from chronic pancreatitis and healthy individuals by (1)H nuclear magnetic resonance-based metabonomic profiles. Clinical biochemistry. 2012 Sep; 45(13-14):1064-9. doi: 10.1016/j.clinbiochem.2012.05.012. [PMID: 22613268]
  • Camilo Pohlenz, Alejandro Buentello, Michael F Criscitiello, Waithaka Mwangi, Roger Smith, Delbert M Gatlin. Synergies between vaccination and dietary arginine and glutamine supplementation improve the immune response of channel catfish against Edwardsiella ictaluri. Fish & shellfish immunology. 2012 Sep; 33(3):543-51. doi: 10.1016/j.fsi.2012.06.005. [PMID: 22728565]
  • Alexandra Sufit, Lindsay B Weitzel, Christine Hamiel, Kelly Queensland, Ira Dauber, Olav Rooyackers, Paul E Wischmeyer. Pharmacologically dosed oral glutamine reduces myocardial injury in patients undergoing cardiac surgery: a randomized pilot feasibility trial. JPEN. Journal of parenteral and enteral nutrition. 2012 Sep; 36(5):556-61. doi: 10.1177/0148607112448823. [PMID: 22623413]
  • Chia-Chou Chu, Yu-Chen Hou, Man-Hui Pai, Chen-Jui Chao, Sung-Ling Yeh. Pretreatment with alanyl-glutamine suppresses T-helper-cell-associated cytokine expression and reduces inflammatory responses in mice with acute DSS-induced colitis. The Journal of nutritional biochemistry. 2012 Sep; 23(9):1092-9. doi: 10.1016/j.jnutbio.2011.06.002. [PMID: 22137260]
  • Paolo Dell' Antone. Energy metabolism in cancer cells: how to explain the Warburg and Crabtree effects?. Medical hypotheses. 2012 Sep; 79(3):388-92. doi: 10.1016/j.mehy.2012.06.002. [PMID: 22770870]
  • A Brassier, C Ottolenghi, N Boddaert, P Sonigo, T Attié-Bitach, A-E Millischer-Bellaiche, G Baujat, V Cormier-Daire, V Valayannopoulos, N Seta, M Piraud, B Chadefaux-Vekemans, C Vianey-Saban, R Froissart, P de Lonlay. [Prenatal symptoms and diagnosis of inherited metabolic diseases]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. 2012 Sep; 19(9):959-69. doi: 10.1016/j.arcped.2012.06.002. [PMID: 22884749]
  • Wilson V Avila-Garcia, Elena Sanchez-Olguin, Andrew G Hulting, Carol Mallory-Smith. Target-site mutation associated with glufosinate resistance in Italian ryegrass (Lolium perenne L. ssp. multiflorum). Pest management science. 2012 Sep; 68(9):1248-54. doi: 10.1002/ps.3286. [PMID: 22488875]
  • Hasmik Grigoryan, He Li, Anthony T Iavarone, Evan R Williams, Stephen M Rappaport. Cys34 adducts of reactive oxygen species in human serum albumin. Chemical research in toxicology. 2012 Aug; 25(8):1633-42. doi: 10.1021/tx300096a. [PMID: 22591159]
  • Y He, Z Yu, I Giegling, L Xie, A M Hartmann, C Prehn, J Adamski, R Kahn, Y Li, T Illig, R Wang-Sattler, D Rujescu. Schizophrenia shows a unique metabolomics signature in plasma. Translational psychiatry. 2012 Aug; 2(?):e149. doi: 10.1038/tp.2012.76. [PMID: 22892715]
  • E Arnáiz, J Bernal, M T Martín, M J Nozal, J L Bernal, L Toribio. Supercritical fluid extraction of free amino acids from broccoli leaves. Journal of chromatography. A. 2012 Aug; 1250(?):49-53. doi: 10.1016/j.chroma.2012.04.066. [PMID: 22608777]
  • Silvia Sookoian, Carlos J Pirola. Alanine and aspartate aminotransferase and glutamine-cycling pathway: their roles in pathogenesis of metabolic syndrome. World journal of gastroenterology. 2012 Aug; 18(29):3775-81. doi: 10.3748/wjg.v18.i29.3775. [PMID: 22876026]
  • Djemil Bencharif, Lamia Amirat-Briand, Annabelle Garand, Marc Anton, Eric Schmitt, Serge Desherces, Guy Delhomme, Marie-Laure Langlois, Paul Barrière, Sandrine Destrumelle, Oscar Vera-Munoz, Daniel Tainturier. The advantages of using a combination of LDL and glutamine in comparison with TRIS egg yolk and Equex® STAMP extenders in the cryopreservation of canine semen. Research in veterinary science. 2012 Aug; 93(1):440-7. doi: 10.1016/j.rvsc.2011.06.027. [PMID: 21824633]
  • Sandra C Blass, Hans Goost, René H Tolba, Birgit Stoffel-Wagner, Koroush Kabir, Christof Burger, Peter Stehle, Sabine Ellinger. Time to wound closure in trauma patients with disorders in wound healing is shortened by supplements containing antioxidant micronutrients and glutamine: a PRCT. Clinical nutrition (Edinburgh, Scotland). 2012 Aug; 31(4):469-75. doi: 10.1016/j.clnu.2012.01.002. [PMID: 22284340]
  • M Caroprese, M Albenzio, R Marino, A Santillo, A Sevi. Immune response and milk production of dairy cows fed graded levels of rumen-protected glutamine. Research in veterinary science. 2012 Aug; 93(1):202-9. doi: 10.1016/j.rvsc.2011.07.015. [PMID: 21840024]
  • Rajnish Kumar Chaturvedi, Thomas Hennessey, Ashu Johri, Shashi Kant Tiwari, Divya Mishra, Swati Agarwal, Yoon Seong Kim, M Flint Beal. Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease. Human molecular genetics. 2012 Aug; 21(15):3474-88. doi: 10.1093/hmg/dds178. [PMID: 22589249]
  • Marco Spangaro, Marta Bosia, Andrea Zanoletti, Margherita Bechi, Federica Cocchi, Adele Pirovano, Cristina Lorenzi, Placido Bramanti, Francesco Benedetti, Enrico Smeraldi, Roberto Cavallaro. Cognitive dysfunction and glutamate reuptake: effect of EAAT2 polymorphism in schizophrenia. Neuroscience letters. 2012 Aug; 522(2):151-5. doi: 10.1016/j.neulet.2012.06.030. [PMID: 22728822]
  • Baljit K Ubhi, John H Riley, Paul A Shaw, David A Lomas, Ruth Tal-Singer, William MacNee, Julian L Griffin, Susan C Connor. Metabolic profiling detects biomarkers of protein degradation in COPD patients. The European respiratory journal. 2012 Aug; 40(2):345-55. doi: 10.1183/09031936.00112411. [PMID: 22183483]
  • Xiao-Zhang Yu, Ping-Ping Shen, Ji-Guang Gu, Yan Zhou, Fu-Zhong Zhang. Evidence of iron cyanides as supplementary nitrogen source to rice seedlings. Ecotoxicology (London, England). 2012 Aug; 21(6):1642-50. doi: 10.1007/s10646-012-0943-y. [PMID: 22684732]
  • Vikram Singh Gaur, U S Singh, Alok Kumar Gupta, Anil Kumar. Influence of different nitrogen inputs on the members of ammonium transporter and glutamine synthetase genes in two rice genotypes having differential responsiveness to nitrogen. Molecular biology reports. 2012 Aug; 39(8):8035-44. doi: 10.1007/s11033-012-1650-8. [PMID: 22531935]
  • Xiao-Zhang Yu, Fu-Zhong Zhang. Activities of nitrate reductase and glutamine synthetase in rice seedlings during cyanide metabolism. Journal of hazardous materials. 2012 Jul; 225-226(?):190-4. doi: 10.1016/j.jhazmat.2012.05.027. [PMID: 22633925]
  • David S Rowlands, Jim Clarke, Jackson G Green, Xiaocai Shi. L-Arginine but not L-glutamine likely increases exogenous carbohydrate oxidation during endurance exercise. European journal of applied physiology. 2012 Jul; 112(7):2443-53. doi: 10.1007/s00421-011-2225-4. [PMID: 22048324]
  • Dan Liu, Yuying Fan, Jie Li, Xiaoge Gao, Miao Hao, Huiting Xue, Guihua Tai. The effects of the carboxyl-terminus amino acids of the Shiga toxin B-subunit on retrograde transport. Molecular medicine reports. 2012 07; 6(1):220-6. doi: 10.3892/mmr.2012.885. [PMID: 22552548]
  • Emiko Kokushi, Seiichi Uno, Tomotaka Harada, Jiro Koyama. ¹H NMR-based metabolomics approach to assess toxicity of bunker a heavy oil to freshwater carp, Cyprinus carpio. Environmental toxicology. 2012 Jul; 27(7):404-14. doi: 10.1002/tox.20653. [PMID: 20882592]
  • Haruko Takeshita, Masahisa Horiuchi, Kimiko Izumo, Hiroaki Kawaguchi, Emi Arimura, Kohji Aoyama, Toru Takeuchi. Long-term voluntary exercise, representing habitual exercise, lowers visceral fat and alters plasma amino acid levels in mice. Environmental health and preventive medicine. 2012 Jul; 17(4):275-84. doi: 10.1007/s12199-011-0249-3. [PMID: 22052204]
  • Suwen Qi, Zhiguang Tu, Xin Ouyang, Linxian Wang, Wujian Peng, Anji Cai, Yong Dai. Comparison of the metabolic profiling of hepatitis B virus-infected cirrhosis and alcoholic cirrhosis patients by using (1) H NMR-based metabonomics. Hepatology research : the official journal of the Japan Society of Hepatology. 2012 Jul; 42(7):677-85. doi: 10.1111/j.1872-034x.2011.00964.x. [PMID: 22404306]
  • Jie Li, Shunli Wang, Shanshan Li, Pei Ge, Xiaohui Li, Wujun Ma, F J Zeller, Sai L K Hsam, Yueming Yan. Variations and classification of toxic epitopes related to celiac disease among α-gliadin genes from four Aegilops genomes. Genome. 2012 Jul; 55(7):513-21. doi: 10.1139/g2012-038. [PMID: 22762506]
  • Benjamín Costas, Cláudia Aragão, Ignacio Ruiz-Jarabo, Luis Vargas-Chacoff, Francisco J Arjona, Juan M Mancera, Maria T Dinis, Luís E C Conceição. Different environmental temperatures affect amino acid metabolism in the eurytherm teleost Senegalese sole (Solea senegalensis Kaup, 1858) as indicated by changes in plasma metabolites. Amino acids. 2012 Jul; 43(1):327-35. doi: 10.1007/s00726-011-1082-0. [PMID: 21947601]
  • Erfan Nur, Dees P Brandjes, Tom Teerlink, Hans-Martin Otten, Ronald P J Oude Elferink, Frits Muskiet, Ludo M Evers, Hugo ten Cate, Bart J Biemond, Ashley J Duits, John-John B Schnog. N-acetylcysteine reduces oxidative stress in sickle cell patients. Annals of hematology. 2012 Jul; 91(7):1097-105. doi: 10.1007/s00277-011-1404-z. [PMID: 22318468]
  • Alena Stancáková, Mete Civelek, Niyas K Saleem, Pasi Soininen, Antti J Kangas, Henna Cederberg, Jussi Paananen, Jussi Pihlajamäki, Lori L Bonnycastle, Mario A Morken, Michael Boehnke, Päivi Pajukanta, Aldons J Lusis, Francis S Collins, Johanna Kuusisto, Mika Ala-Korpela, Markku Laakso. Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men. Diabetes. 2012 Jul; 61(7):1895-902. doi: 10.2337/db11-1378. [PMID: 22553379]
  • Stella Blasel, Ulrich Pilatus, Joerg Magerkurth, Maya von Stauffenberg, Dmitri Vronski, Manuel Mueller, Lars Woeckel, Elke Hattingen. Metabolic gray matter changes of adolescents with anorexia nervosa in combined MR proton and phosphorus spectroscopy. Neuroradiology. 2012 Jul; 54(7):753-64. doi: 10.1007/s00234-011-1001-9. [PMID: 22210349]
  • Min Ju Kim, Soon Jin Lee, Jung Hee Lee, Seung Hoon Kim, Ho Kyung Chun, Seong Hyun Kim, Hyo Keun Lim, Seong Hyeon Yun. Detection of rectal cancer and response to concurrent chemoradiotherapy by proton magnetic resonance spectroscopy. Magnetic resonance imaging. 2012 Jul; 30(6):848-53. doi: 10.1016/j.mri.2012.02.013. [PMID: 22503087]
  • Heena J Shah, S S Lele. In vitro propagation of Dioscorea alata var. purpurae. Applied biochemistry and biotechnology. 2012 Jul; 167(6):1811-7. doi: 10.1007/s12010-012-9658-z. [PMID: 22476929]
  • Ana R Seabra, Patrícia A Pereira, Jörg D Becker, Helena G Carvalho. Inhibition of glutamine synthetase by phosphinothricin leads to transcriptome reprograming in root nodules of Medicago truncatula. Molecular plant-microbe interactions : MPMI. 2012 Jul; 25(7):976-92. doi: 10.1094/mpmi-12-11-0322. [PMID: 22414438]
  • Francesca Rossi, Giulia Bellini, Carlo Tolone, Livio Luongo, Silvia Mancusi, Alfonso Papparella, Craig Sturgeon, Alessio Fasano, Bruno Nobili, Laura Perrone, Sabatino Maione, Emanuele Miraglia del Giudice. The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention. Pharmacological research. 2012 Jul; 66(1):88-94. doi: 10.1016/j.phrs.2012.03.011. [PMID: 22465144]
  • Maria Dorotéia Borges-Santos, Fernando Moreto, Paulo Câmara Marques Pereira, Yong Ming-Yu, Roberto Carlos Burini. Plasma glutathione of HIV⁺ patients responded positively and differently to dietary supplementation with cysteine or glutamine. Nutrition (Burbank, Los Angeles County, Calif.). 2012 Jul; 28(7-8):753-6. doi: 10.1016/j.nut.2011.10.014. [PMID: 22261571]
  • Pavel Hrouzek, Marek Kuzma, Jan Černý, Petr Novák, Radovan Fišer, Petr Simek, Alena Lukešová, Jiří Kopecký. The cyanobacterial cyclic lipopeptides puwainaphycins F/G are inducing necrosis via cell membrane permeabilization and subsequent unusual actin relocalization. Chemical research in toxicology. 2012 Jun; 25(6):1203-11. doi: 10.1021/tx300044t. [PMID: 22551534]
  • Lu Wang, Sean M Harris, Herbert M Espinoza, Valerie McClain, Evan P Gallagher. Characterization of phospholipid hydroperoxide glutathione metabolizing peroxidase (gpx4) isoforms in Coho salmon olfactory and liver tissues and their modulation by cadmium. Aquatic toxicology (Amsterdam, Netherlands). 2012 Jun; 114-115(?):134-41. doi: 10.1016/j.aquatox.2012.02.025. [PMID: 22446825]
  • Oliver J Mace, Marcus Schindler, Sonal Patel. The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine. The Journal of physiology. 2012 Jun; 590(12):2917-36. doi: 10.1113/jphysiol.2011.223800. [PMID: 22495587]
  • M Esbjörnsson, O Rooyackers, B Norman, H C Rundqvist, J Nowak, J Bülow, L Simonsen, E Jansson. Reduction in plasma leucine after sprint exercise is greater in males than in females. Scandinavian journal of medicine & science in sports. 2012 Jun; 22(3):399-409. doi: 10.1111/j.1600-0838.2010.01222.x. [PMID: 22612362]
  • Lisa Mapelli, Claudio Canale, Daniela Pesci, Stefania Averaimo, Fabiana Guizzardi, Valentina Fortunati, Laura Falasca, Mauro Piacentini, Alessandra Gliozzi, Annalisa Relini, Michele Mazzanti, Carla Jodice. Toxic effects of expanded ataxin-1 involve mechanical instability of the nuclear membrane. Biochimica et biophysica acta. 2012 Jun; 1822(6):906-17. doi: 10.1016/j.bbadis.2012.01.016. [PMID: 22330095]
  • Emilee Senkevitch, Juan Cabrera-Luque, Hiroki Morizono, Ljubica Caldovic, Mendel Tuchman. A novel biochemically salvageable animal model of hyperammonemia devoid of N-acetylglutamate synthase. Molecular genetics and metabolism. 2012 Jun; 106(2):160-8. doi: 10.1016/j.ymgme.2012.03.004. [PMID: 22503289]
  • Florence Masaisa, Candace Breman, Jean Bosco Gahutu, Joshua Mukiibi, Joris Delanghe, Jan Philippé. Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating serum hepcidin levels in Rwandese HIV-positive women. Annals of hematology. 2012 Jun; 91(6):911-6. doi: 10.1007/s00277-011-1400-3. [PMID: 22249207]
  • Scott J Walmsley, Dana M Freund, Norman P Curthoys. Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule. American journal of physiology. Renal physiology. 2012 Jun; 302(11):F1465-77. doi: 10.1152/ajprenal.00390.2011. [PMID: 22357915]
  • Diego Cotella, Susanne Radicke, Valentina Cipriani, Maria Cavaletto, Simone Merlin, Antonia Follenzi, Ursula Ravens, Erich Wettwer, Claudio Santoro, Daniele Sblattero. N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels. The international journal of biochemistry & cell biology. 2012 Jun; 44(6):876-85. doi: 10.1016/j.biocel.2012.02.011. [PMID: 22387313]
  • Sibah Hasan, Nayantara Santhi, Alpar S Lazar, Ana Slak, June Lo, Malcolm von Schantz, Simon N Archer, Jonathan D Johnston, Derk-Jan Dijk. Assessment of circadian rhythms in humans: comparison of real-time fibroblast reporter imaging with plasma melatonin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 Jun; 26(6):2414-23. doi: 10.1096/fj.11-201699. [PMID: 22371527]
  • Marià Alemany. The problem of nitrogen disposal in the obese. Nutrition research reviews. 2012 Jun; 25(1):18-28. doi: 10.1017/s0954422411000163. [PMID: 22309896]
  • T Mostafa, L H El-Shahid, A A El Azeem, O Shaker, H Gomaa, H M Abd El Hamid. Androgen receptor-CAG repeats in infertile Egyptian men. Andrologia. 2012 Jun; 44(3):147-51. doi: 10.1111/j.1439-0272.2010.01125.x. [PMID: 21714804]
  • A Da'dara, G Krautz-Peterson, Z Faghiri, P J Skelly. Metabolite movement across the schistosome surface. Journal of helminthology. 2012 Jun; 86(2):141-7. doi: 10.1017/s0022149x12000120. [PMID: 22365312]
  • Wenkai Ren, Yulong Yin, Gang Liu, Xinglong Yu, Yinghui Li, Guan Yang, Teijun Li, Guoyao Wu. Effect of dietary arginine supplementation on reproductive performance of mice with porcine circovirus type 2 infection. Amino acids. 2012 Jun; 42(6):2089-94. doi: 10.1007/s00726-011-0942-y. [PMID: 21617969]
  • Yongjun Luo, Junyu Zhu, Yuqi Gao. Metabolomic analysis of the plasma of patients with high-altitude pulmonary edema (HAPE) using 1H NMR. Molecular bioSystems. 2012 Jun; 8(6):1783-8. doi: 10.1039/c2mb25044f. [PMID: 22498880]
  • Paul Castillo Rodas, Olav Rooyackers, Christina Hebert, Åke Norberg, Jan Wernerman. Glutamine and glutathione at ICU admission in relation to outcome. Clinical science (London, England : 1979). 2012 Jun; 122(12):591-7. doi: 10.1042/cs20110520. [PMID: 22248298]
  • Jian Lei, Dingyuan Feng, Yongliang Zhang, Feng-Qi Zhao, Zhenlong Wu, Ana San Gabriel, Yoshiyuki Fujishima, Hisayuki Uneyama, Guoyao Wu. Nutritional and regulatory role of branched-chain amino acids in lactation. Frontiers in bioscience (Landmark edition). 2012 06; 17(7):2725-39. doi: 10.2741/4082. [PMID: 22652809]
  • Peng Lü, Ji-Wang Zhang, Wei Liu, Jin-Sheng Yang, Shu-Ting Dong, Peng Liu, Deng-Hai Li. [Effects of nitrogen application period on the nitrogen metabolism key enzymes activities and antioxidant characteristics of high-yielding summer maize]. Ying yong sheng tai xue bao = The journal of applied ecology. 2012 Jun; 23(6):1591-8. doi: ". [PMID: 22937648]
  • Supriya Gupta, Sanjay Mohan Gupta, Aniruddha P Sane, Nikhil Kumar. Chlorophyllase in Piper betle L. has a role in chlorophyll homeostasis and senescence dependent chlorophyll breakdown. Molecular biology reports. 2012 Jun; 39(6):7133-42. doi: 10.1007/s11033-012-1545-8. [PMID: 22311037]
  • Kayoko Kita, Toshihide Suzuki, Takafumi Ochi. Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease. The Journal of biological chemistry. 2012 May; 287(22):18163-72. doi: 10.1074/jbc.m112.362699. [PMID: 22493432]
  • Diren Beyoğlu, Robert L Smith, Jeffrey R Idle. Dog bites man or man bites dog? The enigma of the amino acid conjugations. Biochemical pharmacology. 2012 May; 83(10):1331-9. doi: 10.1016/j.bcp.2011.12.031. [PMID: 22227274]
  • Shuantao Liu, Xinlei Zhu, Yang Tan, Shuwei Liu. Isolation and characterization of Glu-1 genes from the St genome of Pseudoroegneria libanotica. Gene. 2012 May; 499(1):154-9. doi: 10.1016/j.gene.2012.03.011. [PMID: 22425973]
  • Susan Cheng, Eugene P Rhee, Martin G Larson, Gregory D Lewis, Elizabeth L McCabe, Dongxiao Shen, Melinda J Palma, Lee D Roberts, Andre Dejam, Amanda L Souza, Amy A Deik, Martin Magnusson, Caroline S Fox, Christopher J O'Donnell, Ramachandran S Vasan, Olle Melander, Clary B Clish, Robert E Gerszten, Thomas J Wang. Metabolite profiling identifies pathways associated with metabolic risk in humans. Circulation. 2012 May; 125(18):2222-31. doi: 10.1161/circulationaha.111.067827. [PMID: 22496159]
  • Liye Sun, Weihong Hu, Qiao Liu, Qinfang Hao, Bo Sun, Qi Zhang, Sha Mao, Jie Qiao, Xianzhong Yan. Metabonomics reveals plasma metabolic changes and inflammatory marker in polycystic ovary syndrome patients. Journal of proteome research. 2012 May; 11(5):2937-46. doi: 10.1021/pr3000317. [PMID: 22428626]
  • Yoichi Ogawa, Nozomu Sakurai, Akira Oikawa, Kosuke Kai, Yoshihiko Morishita, Kumiko Mori, Kanami Moriya, Fumiko Fujii, Koh Aoki, Hideyuki Suzuki, Daisaku Ohta, Kazuki Saito, Daisuke Shibata. High-throughput cryopreservation of plant cell cultures for functional genomics. Plant & cell physiology. 2012 May; 53(5):943-52. doi: 10.1093/pcp/pcs038. [PMID: 22437846]
  • Rahel Elevi Bardavid, Aharon Oren. The amino acid composition of proteins from anaerobic halophilic bacteria of the order Halanaerobiales. Extremophiles : life under extreme conditions. 2012 May; 16(3):567-72. doi: 10.1007/s00792-012-0455-y. [PMID: 22527048]
  • Mario A Jardon, Beheroze Sattha, Katrin Braasch, Amy O Leung, Hélène C F Côté, Michael Butler, Sharon M Gorski, James M Piret. Inhibition of glutamine-dependent autophagy increases t-PA production in CHO cell fed-batch processes. Biotechnology and bioengineering. 2012 May; 109(5):1228-38. doi: 10.1002/bit.24393. [PMID: 22125188]
  • Kisten Sisse Krag Gjetting, Cecilie Karkov Ytting, Alexander Schulz, Anja Thoe Fuglsang. Live imaging of intra- and extracellular pH in plants using pHusion, a novel genetically encoded biosensor. Journal of experimental botany. 2012 May; 63(8):3207-18. doi: 10.1093/jxb/ers040. [PMID: 22407646]
  • Agnieszka Smolinska, Joram M Posma, Lionel Blanchet, Kirsten A M Ampt, Amos Attali, Tinka Tuinstra, Theo Luider, Marek Doskocz, Paul J Michiels, Frederic C Girard, Lutgarde M C Buydens, Sybren S Wijmenga. Simultaneous analysis of plasma and CSF by NMR and hierarchical models fusion. Analytical and bioanalytical chemistry. 2012 May; 403(4):947-59. doi: 10.1007/s00216-012-5871-4. [PMID: 22395451]
  • Areeba Ahmad, Riaz Ahmad. Understanding the mechanism of hepatic fibrosis and potential therapeutic approaches. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. 2012 May; 18(3):155-67. doi: 10.4103/1319-3767.96445. [PMID: 22626794]