Acridone (BioDeep_00000001085)

 

Secondary id: BioDeep_00000017691, BioDeep_00000862324

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


9,10-Dihydro-9-oxoacridine

化学式: C13H9NO (195.0684)
中文名称: 9(10H)-吖啶酮, 吖啶酮
谱图信息: 最多检出来源 Homo sapiens(otcml) 13.1%

分子结构信息

SMILES: C1=C2C(=CC=C1)C(C3=C(N2)C=CC=C3)=O
InChI: InChI=1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 2310
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities[1].
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities[1].

同义名列表

8 个代谢物同义名

9,10-Dihydro-9-oxoacridine; 9,10-dihydroacridin-9-one; 9-azaanthracen-10-one; 9(10H)-acridone; Acridanone; 9-Acridone; Acridone; Acridone



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ABCB1, AKT1, ANXA5, BCL2, EID1, FASN, MSMP, MYC, NQO1, PFKM, TNK1, TP53BP1
Peripheral membrane protein 3 ACHE, ANXA5, TNK1
Endoplasmic reticulum membrane 2 BCL2, STING1
Mitochondrion membrane 1 ABCG2
Nucleus 8 ACHE, AKT1, BCL2, EID1, MYC, NQO1, PFKM, TP53BP1
autophagosome 1 STING1
cytosol 8 AKT1, ANXA5, BCL2, FASN, NQO1, PFKM, PRKCQ, STING1
dendrite 1 NQO1
mitochondrial membrane 1 ABCG2
nuclear body 1 TP53BP1
nucleoplasm 6 ABCG2, AKT1, EID1, MYC, STING1, TP53BP1
Cell membrane 7 ABCB1, ABCG2, ACHE, AKT1, P2RX1, P2RX4, STING1
lamellipodium 1 AKT1
Multi-pass membrane protein 6 ABCB1, ABCG2, ADCY7, P2RX1, P2RX4, STING1
Golgi apparatus membrane 1 STING1
Synapse 2 ACHE, NQO1
cell cortex 1 AKT1
cell junction 1 P2RX4
cell surface 2 ABCB1, ACHE
glutamatergic synapse 3 AKT1, P2RX1, P2RX4
Golgi apparatus 2 ACHE, FASN
Golgi membrane 1 STING1
lysosomal membrane 1 P2RX4
neuromuscular junction 1 ACHE
neuronal cell body 2 NQO1, P2RX4
postsynapse 3 AKT1, P2RX1, P2RX4
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 NQO1
endosome 1 STING1
plasma membrane 12 ABCB1, ABCG2, ACHE, ADCY7, AKT1, BCHE, FASN, P2RX1, P2RX4, PRKCQ, STING1, TNK1
terminal bouton 1 P2RX4
Membrane 14 ABCB1, ABCG2, ACHE, ADCY7, AKT1, ANXA5, BCL2, FASN, MYC, NQO1, P2RX1, P2RX4, PFKM, TNK1
apical plasma membrane 3 ABCB1, ABCG2, PFKM
extracellular exosome 4 ABCB1, ANXA5, FASN, P2RX4
Lysosome membrane 1 P2RX4
endoplasmic reticulum 1 BCL2
extracellular space 3 ACHE, BCHE, MSMP
perinuclear region of cytoplasm 3 ACHE, P2RX4, STING1
mitochondrion 1 BCL2
protein-containing complex 4 AKT1, BCL2, MYC, P2RX1
Secreted 3 ACHE, BCHE, MSMP
extracellular region 3 ACHE, ANXA5, BCHE
Mitochondrion outer membrane 2 BCL2, STING1
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, STING1
Extracellular side 1 ACHE
centriolar satellite 1 PRKCQ
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 ANXA5, P2RX1
dendritic spine 1 P2RX4
cytoplasmic vesicle 1 STING1
microtubule cytoskeleton 1 AKT1
nucleolus 1 MYC
cell-cell junction 1 AKT1
vesicle 1 AKT1
postsynaptic membrane 1 P2RX1
presynaptic active zone membrane 1 P2RX1
Apical cell membrane 2 ABCB1, ABCG2
Cytoplasm, perinuclear region 1 STING1
Membrane raft 2 ABCG2, P2RX1
pore complex 1 BCL2
focal adhesion 1 ANXA5
spindle 1 AKT1
Peroxisome 1 STING1
basement membrane 1 ACHE
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 ANXA5
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 AKT1
chromatin 1 MYC
Cytoplasmic vesicle, autophagosome membrane 1 STING1
autophagosome membrane 1 STING1
Chromosome 1 TP53BP1
cytoplasmic ribonucleoprotein granule 1 EID1
brush border membrane 1 ABCG2
Nucleus, nucleolus 1 MYC
chromosome, telomeric region 1 TP53BP1
blood microparticle 1 BCHE
Lipid-anchor, GPI-anchor 1 ACHE
site of double-strand break 1 TP53BP1
serine/threonine protein kinase complex 1 STING1
nuclear envelope 1 MYC
Chromosome, centromere, kinetochore 1 TP53BP1
Cytoplasmic vesicle membrane 1 STING1
Nucleus, nucleoplasm 1 MYC
specific granule membrane 1 P2RX1
Melanosome 1 FASN
cell body 1 P2RX4
side of membrane 1 ACHE
replication fork 1 TP53BP1
myelin sheath 1 BCL2
secretory granule membrane 2 P2RX1, STING1
endoplasmic reticulum lumen 1 BCHE
kinetochore 1 TP53BP1
RNA polymerase II transcription repressor complex 1 MYC
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 STING1
postsynaptic density membrane 1 P2RX4
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
nuclear envelope lumen 1 BCHE
parallel fiber to Purkinje cell synapse 1 P2RX4
vesicle membrane 1 ANXA5
synaptic cleft 1 ACHE
external side of apical plasma membrane 2 ABCB1, ABCG2
Rough endoplasmic reticulum 1 MYC
DNA repair complex 1 TP53BP1
sperm principal piece 1 PFKM
Myc-Max complex 1 MYC
6-phosphofructokinase complex 1 PFKM
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
[Isoform H]: Cell membrane 1 ACHE
glycogen granule 1 FASN
STING complex 1 STING1
nucleoplasmic reticulum 1 MYC


文献列表

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