Barbamide (BioDeep_00000010840)

   

natural product


代谢物信息卡片


Barbamide

化学式: C20H23Cl3N2O2S (460.0546)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(natural_products) 10.23%

分子结构信息

SMILES: CC(CC(=CC(=O)N(C)C(CC1=CC=CC=C1)C2=NC=CS2)OC)C(Cl)(Cl)Cl
InChI: InChI=1S/C20H23Cl3N2O2S/c1-14(20(21,22)23)11-16(27-3)13-18(26)25(2)17(19-24-9-10-28-19)12-15-7-5-4-6-8-15/h4-10,13-14,17H,11-12H2,1-3H3/b16-13+

描述信息

同义名列表

1 个代谢物同义名

Barbamide



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 EGFR, FOXO1, SLC6A3, TUBB4B
Peripheral membrane protein 1 AP2S1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 1 EGFR
Nucleus 4 EGFR, FOXO1, KLF6, TUBB4B
cytosol 4 AP2S1, FOXO1, KLF6, TUBB4B
nucleoplasm 2 FOXO1, KLF6
Cell membrane 4 AP2S1, EGFR, SLC6A3, TRPV1
Cytoplasmic side 1 AP2S1
ruffle membrane 1 EGFR
Cell projection, axon 1 SLC6A3
Early endosome membrane 1 EGFR
Multi-pass membrane protein 3 SLC6A3, TMEM97, TRPV1
cell junction 1 EGFR
cell surface 2 EGFR, SLC6A3
glutamatergic synapse 1 EGFR
Golgi membrane 1 EGFR
neuronal cell body 2 SLC6A3, TRPV1
postsynapse 1 AP2S1
presynaptic membrane 1 SLC6A3
Lysosome 1 TMEM97
Presynapse 1 AP2S1
endosome 1 EGFR
plasma membrane 5 AP2S1, EGFR, SLC6A3, TMEM97, TRPV1
Membrane 4 EGFR, SLC6A3, TMEM97, TRPV1
apical plasma membrane 1 EGFR
axon 1 SLC6A3
basolateral plasma membrane 1 EGFR
extracellular exosome 1 TUBB4B
endoplasmic reticulum 1 TMEM97
extracellular space 1 EGFR
perinuclear region of cytoplasm 1 EGFR
mitochondrion 1 FOXO1
protein-containing complex 1 EGFR
intracellular membrane-bounded organelle 2 AP2S1, KLF6
Single-pass type I membrane protein 1 EGFR
extracellular region 1 TUBB4B
cytoplasmic side of plasma membrane 1 AP2S1
neuronal cell body membrane 1 SLC6A3
Nucleus membrane 1 TMEM97
nuclear membrane 2 EGFR, TMEM97
external side of plasma membrane 1 TRPV1
Extracellular vesicle 1 TUBB4B
microtubule cytoskeleton 1 TUBB4B
nucleolus 1 KLF6
postsynaptic membrane 2 SLC6A3, TRPV1
Membrane raft 2 EGFR, SLC6A3
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 EGFR
microtubule 1 TUBB4B
GABA-ergic synapse 1 TRPV1
flotillin complex 1 SLC6A3
intracellular vesicle 1 EGFR
Postsynaptic cell membrane 1 TRPV1
receptor complex 1 EGFR
Cell projection, neuron projection 2 SLC6A3, TRPV1
neuron projection 1 SLC6A3
chromatin 2 FOXO1, KLF6
cell periphery 1 AP2S1
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
fibrillar center 1 KLF6
Endomembrane system 1 TMEM97
axonemal microtubule 1 TUBB4B
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
axon terminus 1 SLC6A3
endocytic vesicle membrane 1 AP2S1
rough endoplasmic reticulum membrane 1 TMEM97
azurophil granule lumen 1 TUBB4B
clathrin-coated endocytic vesicle 1 AP2S1
clathrin-coated endocytic vesicle membrane 2 AP2S1, EGFR
endolysosome membrane 1 AP2S1
dopaminergic synapse 1 SLC6A3
membrane coat 1 AP2S1
Rough endoplasmic reticulum 1 TMEM97
Membrane, coated pit 1 AP2S1
Cell projection, dendritic spine membrane 1 TRPV1
dendritic spine membrane 1 TRPV1
AP-2 adaptor complex 1 AP2S1
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR


文献列表

  • J Orjala, W H Gerwick. Barbamide, a chlorinated metabolite with molluscicidal activity from the Caribbean cyanobacterium Lyngbya majuscula. Journal of natural products. 1996 Apr; 59(4):427-30. doi: 10.1021/np960085a. [PMID: 8699186]