Classification Term: 170357
Piperidine alkaloids (ontology term: 96165bc32e803be3963fe038089a6031)
found 144 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Lysine alkaloids
Child Taxonomies: There is no child term of current ontology term.
Guvacoline
The methyl ester of guvacine.
Carpaine
Pseudocarpaine is found in fruits. Minor alkaloid from leaves of Carica papaya (papaya Alkaloid from leaves of Carica papaya (papaya)
Piperettine
C19H21NO3 (311.15213560000007)
Alkaloid from the dried fruits of Piper nigrum (pepper). Piperettine is found in herbs and spices and pepper (spice). Piperettine is found in herbs and spices. Piperettine is an alkaloid from the dried fruits of Piper nigrum (pepper
Acetophenone, 4'-hydroxy-3'-methoxy-2-(2-piperidyl)-
Jervine
C27H39NO3 (425.29297840000004)
Norhygrine
Norhygrine is a member of the class of compounds known as beta-amino ketones. Beta-amino ketones are ketones containing a carboxylic acid, and an amine group attached to the beta carbon atom, relative to the C=O group. Norhygrine is soluble (in water) and an extremely weak acidic compound (based on its pKa). Norhygrine can be found in pomegranate, which makes norhygrine a potential biomarker for the consumption of this food product.
Jervine
C27H39NO3 (425.29297840000004)
Jervine is a member of piperidines. Jervine is a natural product found in Veratrum stamineum, Veratrum grandiflorum, and other organisms with data available. Jervine is a steroidal alkaloid with molecular formula C27H39NO3 which is derived from the Veratrum plant genus. Similar to cyclopamine, which also occurs in the Veratrum genus, it is a teratogen implicated in birth defects when consumed by animals during a certain period of their gestation. D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents > D014704 - Veratrum Alkaloids Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM[1]. Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties[2]. Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM[1]. Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties[2].
3-[3-(4-hydroxy-3-methoxyphenyl)propanoyl]-7-oxa-3-azabicyclo[4.1.0]heptan-2-one
Piperettine
C19H21NO3 (311.15213560000007)
Carpaine
An alkaloid that forms a major component of the papaya leaves and has been shown to exhibit cardiovascular effects.
(3r,5s,7ar,11as)-3-(chloromethyl)-5-hexyl-1h,2h,3h,5h,6h,7h,7ah,11h-pyrrolo[2,1-j]quinolin-10-one
C19H30ClNO (323.20158000000004)
2-methyl-5-(octa-1,3-dien-1-yl)-decahydroquinolin-3-ol
(4z,6z,8z,12r,13r,29s,31s)-1,16-diazatetracyclo[27.3.1.1¹²,¹⁶.0¹³,³¹]tetratriaconta-4,6,8-trien-3-ol
C32H54N2O (482.42359139999996)
(2e,4e,8z)-1-(piperidin-1-yl)tetradeca-2,4,8-trien-1-one
16-methyl-5-oxa-7-azatetracyclo[5.4.3.3²,⁶.0¹,⁶]heptadecane-4,11-dione
1-[(2s,6r)-6-[(2r)-2-hydroxypentyl]piperidin-2-yl]propan-2-one
(2r,3r,4s,5r,6r)-2-{[(2s,3s,5r)-2-[(1s)-1-[(3r,6ar,11as,11bs)-3-hydroxy-10,11b-dimethyl-1h,2h,3h,4h,6h,6ah,11h,11ah-cyclohexa[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
5-(5-hydroxyoctyl)-2-methyl-decahydroquinolin-3-yl oct-2-enoate
1-[(1r,9s,10s,16r)-16-methyl-6,14-diazatetracyclo[7.5.3.0¹,¹⁰.0²,⁷]heptadec-2(7)-en-6-yl]ethanone
5-(2h-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)pent-2-en-1-one
C16H19NO3 (273.13648639999997)
(1s,2s,3r,4e,6z,9z,16s,18r,32s,33s)-2,3-dihydroxy-14,29-diazapentacyclo[16.14.1.0¹,¹⁴.0¹⁶,³².0²⁹,³³]tritriaconta-4,6,9-triene-18-carbaldehyde
(2e)-3-(6,7-dimethoxy-2h-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-one
(2s,3s,4r)-3-methyl-2-[(1e,3e)-4-phenylbuta-1,3-dien-1-yl]piperidin-4-yl acetate
(2r,4r,5s)-5-amino-2-[(6e,8e)-trideca-6,8-dien-1-yl]piperidin-4-ol
(3s,3'r,3'ar,6's,6as,6bs,7'as,9s,11as,11br)-3',6',10,11b-tetramethyl-3-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a-hexadecahydro-3'h-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridin]-11-one
1,3-bis(piperidin-2-yl)propan-2-one
C13H24N2O (224.18885339999997)
3-hydroxy-9-[1-(3-hydroxy-5-methylpiperidin-2-yl)ethyl]-10,11b-dimethyl-1h,2h,3h,4h,4ah,6h,6ah,6bh,7h,8h,9h,11h,11ah-cyclohexa[a]fluoren-5-one
(2s,3s,4as,5s,8ar)-2-methyl-5-[(1z,3e)-octa-1,3-dien-1-yl]-decahydroquinolin-3-yl 2-hydroxyacetate
(2e,4e,6e,8r)-8-hydroxy-1-[(2r)-2-(hydroxymethyl)pyrrolidin-1-yl]-6-methyldodeca-2,4,6-trien-1-one
1-[2,6-bis(2h-1,3-benzodioxol-5-yl)-5-(piperidine-1-carbonyl)cyclohex-3-ene-1-carbonyl]piperidine
C32H36N2O6 (544.2573236000001)
1-[5-(2h-1,3-benzodioxol-5-yl)-4-pentyl-6-(piperidine-1-carbonyl)cyclohex-2-ene-1-carbonyl]piperidine
C30H42N2O4 (494.31444120000003)
(3r,5s,7r,7ar,11ar)-5-butyl-3-(isothiocyanatomethyl)-decahydro-1h-pyrrolo[2,1-j]quinolin-7-yl acetate
1-(octahydro-1h-quinolizin-1-ylmethyl)piperidine-2,6-dione
C15H24N2O2 (264.18376839999996)
3-[2-(2h-1,3-benzodioxol-5-yl)-4-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-3-(piperidine-1-carbonyl)cyclobutyl]-1-(piperidin-1-yl)prop-2-en-1-one
(2r,3r,6r)-6-(11-hydroxydodecyl)-2-methylpiperidin-3-ol
4-[(5s,6e)-7-[(2r,3s,4s,5s,6e,10e)-4,5-dihydroxy-3-methyl-12-oxo-1-oxacyclododeca-6,10-dien-2-yl]-5-methyl-4-oxooct-6-en-1-yl]-6-hydroxy-4,5-dihydro-3h-pyridin-2-one
(3r,5r,9ar)-5-methyl-3-(non-8-en-1-yl)-octahydro-1h-pyrrolo[1,2-a]azepine
6-[5-(hydroxymethyl)-1-methylpiperidin-3-yl]pyridin-2-ol
1-[(1s,2s,5r,6r)-5-(2h-1,3-benzodioxol-5-yl)-6-[(1e)-2-(2h-1,3-benzodioxol-5-yl)ethenyl]-2-(pyrrolidine-1-carbonyl)cyclohex-3-ene-1-carbonyl]pyrrolidine
(2e,4e)-1-(pyrrolidin-1-yl)octadeca-2,4-dien-1-one
3-(7-methoxy-2h-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)prop-2-en-1-one
11-[(2r,5r,6r)-5-hydroxy-6-methylpiperidin-2-yl]undecanoic acid
C17H33NO3 (299.24603079999997)
(4e,6z,19z,22z,29s,30r)-1,16-diazatetracyclo[27.3.1.1¹²,¹⁶.0¹⁴,³⁰]tetratriaconta-4,6,12,14,19,22-hexaen-34-yl
11-(but-3-en-1-yl)-2,11-diazatricyclo[7.3.1.0²,⁷]tridecan-8-one
C15H24N2O (248.18885339999997)
n-[3-(n-{3-[(6z)-1-azacyclopentadec-6-en-1-yl]propyl}acetamido)propyl]ethanimidic acid
(21ar)-10-(3-aminopropyl)-octadecahydro-1h-pyrido[1,2-f]1,6-diazacyclooctadecan-11-one
(2e)-5-(6-methoxy-2h-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)pent-2-en-1-one
1-[(1s,2s,5s,6r)-5,6-bis[(1e)-2-(2h-1,3-benzodioxol-5-yl)ethenyl]-2-(piperidine-1-carbonyl)cyclohex-3-ene-1-carbonyl]piperidine
9,30-dioxa-11,25-diazapentacyclo[20.6.2.2⁸,¹¹.0¹⁰,¹⁵.0²⁵,²⁹]dotriacontane-1,15-diol
(10z)-5-ethyl-1-oxa-4-azacyclopentadec-10-en-15-one
(2e)-3-(4-methoxyphenyl)-1-(pyrrolidin-1-yl)prop-2-en-1-one
C14H17NO2 (231.12592220000002)
(2z,4e)-5-(6-methoxy-2h-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)penta-2,4-dien-1-one
5-(but-2-en-1-ylidene)-1h,2h,3h-cyclopenta[b]pyridin-4-one
1-{16-methyl-6,14-diazatetracyclo[7.5.3.0¹,¹⁰.0²,⁷]heptadec-2(7)-en-6-yl}ethanone
1-(pyrrolidin-1-yl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one
5-hydroxy-8-methoxy-14-oxo-24-azapentacyclo[14.7.1.1²,⁶.1⁷,¹¹.0²⁰,²⁴]hexacosa-2,4,6(26),7(25),8,10-hexaen-22-yl acetate
C28H33NO5 (463.23586080000007)
5-(4-hydroxy-3-methoxyphenyl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
2-methyl-6-(11-oxododecyl)piperidin-3-yl (2e)-3-(4-hydroxyphenyl)prop-2-enoate
C27H41NO4 (443.30354260000007)
(4e,12r,14r,19z,22z,29r,30s)-1,16-diazatetracyclo[27.3.1.1¹²,¹⁶.0¹⁴,³⁰]tetratriaconta-4,19,22-triene
8-[(2-oxopiperidin-1-yl)methyl]-octahydro-2h-quinoline-1-carbaldehyde
1-[(1s,2s,3r,4r)-2-(3,4-dimethoxyphenyl)-4-(7-methoxy-2h-1,3-benzodioxol-5-yl)-3-(2-oxo-5,6-dihydropyridine-1-carbonyl)cyclobutanecarbonyl]-5,6-dihydropyridin-2-one
9,23-dimethyl-30-oxa-11,25-diazapentacyclo[20.6.2.1⁷,¹¹.0²⁵,²⁹.0¹⁵,³¹]hentriacontan-8-one
C30H52N2O2 (472.40285719999997)
(3s,3'r,3'as,6's,6as,6bs,7'ar,9r,11r,11as,11br)-3',6',10,11b-tetramethyl-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a-hexadecahydro-1h,3'h-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-3,11-diol
(2s,3s,4s)-4-chloro-2-[(3z,5e)-hepta-3,5-dien-1-yl]piperidin-3-ol
(2r,4s,5r)-5-amino-2-[(1e,3e,8e,10e)-pentadeca-1,3,8,10-tetraen-1-yl]piperidin-4-ol
n-{1-[3-(methylsulfanyl)prop-2-enoyl]pyrrolidin-2-yl}-2-phenylethanimidic acid
6-hydroxy-4-[(2r,5s,6e)-2-hydroxy-7-[(2r,3s,4r,6e,10e)-4-hydroxy-3-methyl-12-oxo-1-oxacyclododeca-6,10-dien-2-yl]-5-methyl-4-oxooct-6-en-1-yl]-4,5-dihydro-3h-pyridin-2-one
(11z)-5-propyl-1-oxa-4-azacyclohexadec-11-en-16-one
(3r,5s,7ar,11ar)-5-hexyl-3-(methoxymethyl)-decahydropyrrolo[2,1-j]quinolin-7-one
(2e,4e,12z)-1-(piperidin-1-yl)octadeca-2,4,12-trien-1-one
(6z,11s,19z)-1,14-diazatetracyclo[21.3.1.1¹⁰,¹⁴.0¹¹,²⁵]octacosa-6,19,24-triene
6-hydroxy-4-[(2r,5s,6e)-2-hydroxy-7-[(2s,3s,4s,5s,6e,10e)-4-hydroxy-5-methoxy-3-methyl-12-oxo-1-oxacyclododeca-6,10-dien-2-yl]-5-methyl-4-oxooct-6-en-1-yl]-4,5-dihydro-3h-pyridin-2-one
(2e,4e)-1-(piperidin-1-yl)deca-2,4-diene-1,6-dione
(1s,4r,5r,6s)-5-(2h-1,3-benzodioxol-5-yl)-n-(2-methylpropyl)-4-pentyl-6-(piperidine-1-carbonyl)cyclohex-2-ene-1-carboximidic acid
C29H42N2O4 (482.31444120000003)
2-amino-3-{[(7z)-10-hydroxy-12-[(2e)-7-hydroxy-8-(2-hydroxy-6-oxo-4,5-dihydro-3h-pyridin-4-yl)-4-methyl-5-oxooct-2-en-2-yl]-9-methoxy-11-methyl-2-oxo-1-oxacyclododec-7-en-4-yl]sulfanyl}propanoic acid
6-methoxy-6-methyl-1-[4-(4-methyl-5-oxofuran-2-ylidene)butyl]-2h,3h,4h,7h-cyclopenta[b]pyridin-5-one
1-(2h-1,3-benzodioxol-5-yl)-2-(piperidin-1-yl)ethanone
2-methyl-6-(13-oxotetradecyl)piperidin-3-yl 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
(2s,3r)-2-[(2s)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-3-ol
C14H21NO2 (235.15722060000002)
(3-aminopropyl)[3-(1-azacyclotridecan-1-yl)propyl]amine
(1s,3s,5s,7s,9s,11s)-3,7,11-trimethyl-2,6,10,13-tetraazatricyclo[7.3.1.0⁵,¹³]tridecane
(5e)-5-[(2e)-but-2-en-1-ylidene]-1h-cyclopenta[b]pyridin-4-one
(4z,12s,14s,18r,19z,21z,29s,30r)-1,16-diazatetracyclo[27.3.1.1¹²,¹⁶.0¹⁴,³⁰]tetratriaconta-4,19,21-trien-18-ol
C32H54N2O (482.42359139999996)
(2r)-1-[(2s,6s)-6-[(2s)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]propan-2-ol
C17H27NO2 (277.20416819999997)
(1s,8s,10r,15r,22s,29r)-10-methyl-9,30-dioxa-11,25-diazapentacyclo[20.6.2.2⁸,¹¹.0¹⁰,¹⁵.0²⁵,²⁹]dotriacontan-1-ol
C29H52N2O3 (476.39777219999996)
(3-aminopropyl)({3-[(5z)-1-azacyclotetradec-5-en-1-yl]propyl})amine
(5z)-5-ethylidene-1h,2h,3h-cyclopenta[b]pyridin-6-one
22-(acetyloxy)-5,8-dimethoxy-24-azapentacyclo[14.7.1.1²,⁶.1⁷,¹¹.0²⁰,²⁴]hexacosa-2,4,6(26),7(25),8,10-hexaen-14-yl acetate
(2r,4r)-2-[(2r)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-4-ol
C14H21NO2 (235.15722060000002)
9-(2h-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)nona-2,4,8-trien-1-one
C21H25NO3 (339.18343400000003)
(4e)-5-(2h-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
C17H19NO3 (285.13648639999997)
5-(6-methoxy-2h-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)pent-2-en-1-one
(1r,11r,13s,14s,24r,26s)-13,26-dimethyl-2,15-dioxa-12,25-diazatricyclo[22.2.2.2¹¹,¹⁴]triacontane-3,16-dione
9-(2h-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)nona-2,4,8-trien-1-one
C20H23NO3 (325.16778480000005)
(2s,4s)-2-[(1e,3e)-penta-1,3-dien-1-yl]piperidin-4-ol
(3r,4e,6e,8z,12r,13r,29s,31s)-1,16-diazatetracyclo[27.3.1.1¹²,¹⁶.0¹³,³¹]tetratriaconta-4,6,8-trien-3-ol
C32H54N2O (482.42359139999996)
3-(4-hydroxy-3-methoxyphenyl)-1-(piperidin-1-yl)prop-2-en-1-one
C15H19NO3 (261.13648639999997)
6-hydroxy-4-[(2r,5s,6e)-2-hydroxy-7-[(2r,3s,4s,5s,6e,10e)-4-hydroxy-5-methoxy-3-methyl-12-oxo-1-oxacyclododeca-6,10-dien-2-yl]-5-methyl-4-oxooct-6-en-1-yl]-4,5-dihydro-3h-pyridin-2-one
1-[(1r,2s,4as,8as)-2-(2h-1,3-benzodioxol-5-yl)-1,2,4a,5,6,7,8,8a-octahydronaphthalene-1-carbonyl]pyrrolidine
1-[3-(pyrrolidin-2-yl)-5,6-dihydro-4h-pyridin-1-yl]ethanone
(2s,6r,7s,8s)-7-[(1e)-buta-1,3-dien-1-yl]-2-(penta-3,4-dien-1-yl)-1-azaspiro[5.5]undecan-8-ol
5-(4-hydroxy-3-methoxyphenyl)-1-(piperidin-1-yl)pent-2-en-1-one
7-(2h-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)hept-2-en-1-one
C19H25NO3 (315.18343400000003)
{5-hexyl-decahydro-1h-pyrrolo[2,1-j]quinolin-3-yl}methanol
1-[(2r,6r)-6-[(2s)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]pentan-2-one
(1r,7r,9r,15r,21s,23s,29r,30s)-9,23-dimethyl-11,25-diazapentacyclo[19.7.1.1⁷,¹¹.0²⁵,²⁹.0¹⁵,³⁰]triacontane-8,22-dione
(2e,4e)-7-(2h-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)hepta-2,4-dien-1-one
C19H23NO3 (313.16778480000005)
5-hexyl-3-(methoxymethyl)-decahydropyrrolo[2,1-j]quinolin-7-one
(1s,6s)-3-(3-phenylpropanoyl)-7-oxa-3-azabicyclo[4.1.0]heptan-2-one
(6z,12r,13r,21z,27r,29r)-1,16-diazatetracyclo[25.3.1.1¹²,¹⁶.0¹³,²⁹]dotriaconta-6,21-diene
(2e,6e)-7-(2h-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)hepta-2,6-dien-1-one
C19H23NO3 (313.16778480000005)
(3-aminopropyl)({3-[(6z)-1-azacyclopentadec-6-en-1-yl]propyl})amine
(2e)-3-(4-hydroxy-3-methoxyphenyl)-1-(piperidin-1-yl)prop-2-en-1-one
C15H19NO3 (261.13648639999997)