Chemical Formula: C10H11NO2
Chemical Formula C10H11NO2
Found 186 metabolite its formula value is C10H11NO2
5-Hydroxytryptophol
5-Hydroxytryptophol is a relatively minor metabolite of serotonin that is excreted primarily as the glucuronide conjugate in human urine. 5-Hydroxytryptophol becomes more important quantitatively during alcohol intoxication, when a shift in the metabolism of serotonin occurs from 5-hydroxyindole acetic acid toward increased (15-fold higher) formation of 5-hydroxytryptophol due to the inhibition of aldehyde dehydrogenase by ethanol-derived acetaldehyde. Urinary excretion of 5-hydroxytryptophol has also been shown to be markedly increased for several hours following intake of foods rich in serotonin, such as bananas. Wide interspecies variation has been reported in the metabolism serotonin to 5-hydroxytryptophol; 5-Hydroxytryptophol makes up 35\\\% of the excreted serotonin metabolites in the rat on average and 10 to 20\\\% in several other species. Human UDP-glucuronosyltransferase 1A6 (UGT1A6) plays a predominant role in the glucuronidation of 5-hydroxytryptophol by human liver microsomes. (PMID 15258112) [HMDB]. 5-Hydroxytryptophol is found in many foods, some of which are climbing bean, macadamia nut (m. tetraphylla), pepper (c. frutescens), and scarlet bean. 5-Hydroxytryptophol is a relatively minor metabolite of serotonin that is excreted primarily as the glucuronide conjugate in human urine. 5-Hydroxytryptophol becomes more important quantitatively during alcohol intoxication, when a shift in the metabolism of serotonin occurs from 5-hydroxyindole acetic acid toward increased (15-fold higher) formation of 5-hydroxytryptophol due to the inhibition of aldehyde dehydrogenase by ethanol-derived acetaldehyde. Urinary excretion of 5-hydroxytryptophol has also been shown to be markedly increased for several hours following intake of foods rich in serotonin, such as bananas. Wide interspecies variation has been reported in the metabolism serotonin to 5-hydroxytryptophol; 5-Hydroxytryptophol makes up 35\\\% of the excreted serotonin metabolites in the rat on average and 10 to 20\\\% in several other species. Human UDP-glucuronosyltransferase 1A6 (UGT1A6) plays a predominant role in the glucuronidation of 5-hydroxytryptophol by human liver microsomes. (PMID 15258112). 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.
Plantagonine
Plantagonine is found in fruits. Plantagonine is an alkaloid from Plantago psyllium (African plantain). Alkaloid from Plantago psyllium (African plantain). Plantagonine is found in fruits.
1,2-Dehydrosalsolinol
1,2-dehydrosalsolinol(1-methyl-6,7-dihydroxy-3,4-dihydroisoquinolines) is formed through the decarboxylation of salsolinol-1-carboxylic acid (1-methyl-6,7-dihydroxy-1,2,3,4- tetrahydroisoquinoline-1-carboxylic acid), a novel endogenous catecholic adduct of dopamine and pyruvic acid, examined in nuclei-free homogenates of rat liver, whole brain, and kidney, as well as in buffer only. Liquid chromatographic analysis of incubations for varying times (30 min to 5 h) showed that the tetrahydroisoquinoline substrate decarboxylated oxidatively, forming the DSAL (PMID: 3369867). It is involved in Tyrosine Metabolism. 1,2-dehydrosalsolinol(1-methyl-6,7-dihydroxy-3,4-dihydroisoquinolines) is formed through the decarboxylation of salsolinol-1-carboxylic acid (1-methyl-6,7-dihydroxy-1,2,3,4- tetrahydroisoquinoline-1-carboxylic acid), a novel endogenous catecholic adduct of dopamine and pyruvic acid, examined in nuclei-free homogenates of rat liver, whole brain, and kidney, as well as in buffer only. Liquid chromatographic analysis of incubations for varying times (30 min to 5 h) showed that the tetrahydroisoquinoline substrate decarboxylated oxidatively, forming the DSAL (PMID: 3369867)
2-Propenyl 2-aminobenzoate
2-Propenyl 2-aminobenzoate is a flavour ingredient. Flavour ingredient
5-[2H-Pyrrol-4-(3H)-ylidenemethyl]-2-furanmethanol
Putative proline-derived Maillard product formed in model reactions with proline and ascorbic acid. Putative proline-derived Maillard product formed in model reactions with proline and ascorbic acid
N,N-dimethylindoliumolate
This compound belongs to the family of Indoles and Derivatives. These are compounds containing an indole moiety, which consists of pyrrole ring fused to benzene to form 2,3-benzopyrrole.
1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
indole-3-glycol
Indole-3-glycol is a member of the class of compounds known as 3-alkylindoles. 3-alkylindoles are compounds containing an indole moiety that carries an alkyl chain at the 3-position. Indole-3-glycol is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Indole-3-glycol can be found in a number of food items such as common wheat, common pea, japanese persimmon, and broccoli, which makes indole-3-glycol a potential biomarker for the consumption of these food products.
5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
alpha-(4-Hydroxy-phenoxy)-isobutyronitril|alpha-(4-hydroxy-phenoxy)-isobutyronitrile
Di-Me ether,nitrile-(3,4-Dihydroxyphenyl)acetic acid
5-Hydroxytryptophol
5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.
3-[5-(Hydroxymethyl)furfurylidene]-1-pyrroline
2H-INDOL-2-ONE, 1,3-DIHYDRO-5-HYDROXY-1,3-DIMETHYL-
D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
1-(3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)ethanone
2,2-Dimethyl-2,3-Dihydro-Benzo[E][1,3]Oxazin-4-One
(S)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID
(R)-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid
(S)-1,2,3,4-TETRAHYDRO-QUINOLINE-2-CARBOXYLIC ACID
(R)-1,2,3,4-TETRAHYDRO-QUINOLINE-2-CARBOXYLIC ACID
Benzene, 1-[(1R)-1-isocyanatoethyl]-3-methoxy- (9CI)
Benzene, 1-[(1S)-1-isocyanatoethyl]-3-methoxy- (9CI)
1-(2-methylpyridin-4-yl)cyclopropane-1-carboxylic acid
2,3-dihydro-1h-indole-2-carboxylic acid methyl ester
3a,4,7,7a-tetrahydro-4,7-ethano-1H-isoindole-1,3(2H)-dione
4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde
(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone
D000890 - Anti-Infective Agents > D023303 - Oxazolidinones