Histamine (BioDeep_00000001677)

 

Secondary id: BioDeep_00000398719, BioDeep_00000860582

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


2-(1H-imidazol-4-yl)ethan-1-amine

化学式: C5H9N3 (111.0796)
中文名称: 组胺 二盐酸盐, 组胺, 2-(3H-咪唑-4-基)-乙胺
谱图信息: 最多检出来源 Homo sapiens(feces) 8.99%

Reviewed

Last reviewed on 2024-07-03.

Cite this Page

Histamine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/histamine (retrieved 2024-12-23) (BioDeep RN: BioDeep_00000001677). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(CN)C1=CN=CN1
InChI: InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

描述信息

An amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.; Histamine is a biogenic amine involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine triggers the inflammatory response. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and other proteins, in order to allow them to engage foreign invaders in the affected tissues. It is found in virtually all animal body cells.[citation needed]; Histamine is derived from the decarboxylation of the amino acid histidine, a reaction catalyzed by the enzyme L-histidine decarboxylase. It is a hydrophilic vasoactive amine.
Histamine is an amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. Histamine can be found in Photobacterium phosphoreum and Lactobacillus (PMID:17066936). Histamine belongs to the class of organic compounds known as 2-arylethylamines. These are primary amines that have the general formula RCCNH2, where R is an organic group. High amounts of histamine have been found in spinach, oats and ryes. Another foods such as green beans, broccoli, and beetroots also contain histamine but in lower concentrations. Histamine has also been detected but not quantified in several different foods, such as groundcherries, carobs, bok choy, biscuits, and longans.
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D017442 - Histamine Agonists

Histamine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=51-45-6 (retrieved 2024-07-03) (CAS RN: 51-45-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

同义名列表

31 个代谢物同义名

2-(1H-imidazol-4-yl)ethan-1-amine; 2-(1H-Imidazol-5-yl)ethylamine; 2-(1H-Imidazol-4-yl)ethylamine; 2-(1H-imidazol-5-yl)ethanamine; 2-(1H-Imidazol-4-yl)ethanamine; 2-(3H-Imidazol-4-yl)ethylamine; 4-(2-Aminoethyl)-1H-imidazole; beta-Imidazolyl-4-ethylamine; beta-Aminothethylglyoxaline; 2-Imidazol-4-yl-ethylamine; 2-(4-Imidazolyl)ethanamine; 2-(4-Imidazolyl)ethylamine; 4-(2-Aminoethyl)imidazole; Β-imidazolyl-4-ethylamine; 1H-Imidazole-4-ethanamine; beta-Aminoethylglyoxaline; 2-Imidazol-4-ylethylamine; b-Imidazolyl-4-ethylamine; beta-Aminoethylimidazole; Imidazole-4-ethylamine; 4-Imidazoleethylamine; 5-Imidazoleethylamine; Ergotidine; Theramine; Histamine; Ergamine; Eramin; HSM; Histamine; Histamine; Histamine



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(1)

BioCyc(0)

PlantCyc(0)

代谢反应

134 个相关的代谢反应过程信息。

Reactome(35)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(1)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(97)

  • Chlorphenamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Pheniramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Dexchlorpheniramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Brompheniramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Dexbrompheniramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Triprolidine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Dimetindene H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Mepyramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Antazoline H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Chloropyramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Talastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Tripelennamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Histapyrrodine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Methapyrilene H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Thonzylamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Diphenhydramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Carbinoxamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Doxylamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Orphenadrine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Bromodiphenhydramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Clemastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Chlorphenoxamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Diphenylpyraline H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Phenyltoloxamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Cyclizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Chlorcyclizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Hydroxyzine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Meclizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Buclizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Oxatomide H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Cetirizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Cinnarizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Levocetirizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Promethazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Alimemazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Cyproheptadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Phenbenzamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Fenethazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Hydroxyethylpromethazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Isothipendyl H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Mequitazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Methdilazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Oxomemazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Azatadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Ketotifen H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Doxepin H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Acrivastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Astemizole H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Bepotastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Bilastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Loratadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Desloratadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Ebastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Terfenadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Fexofenadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Levocabastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Mizolastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Rupatadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Olopatadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Azelastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Thiazinamium H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Quifenadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Betahistine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Emedastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Flunarizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Mebhydrolin H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Phenindamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Epinastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Tolpropamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Embramine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Latrepirdine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Thenyldiamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Propiomazine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Clocinizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Homochlorcyclizine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Temelastine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Alcaftadine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Bamipine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Deptropine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Quetiapine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Mirtazapine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Pimethixene H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Pyrrobutamine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Thenalidine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Tritoqualine H1-Antihistamine Action: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Histamine H1 Receptor Activation: Histamine H1 receptor (Homo sapiens)_G q (Homo sapiens)_Guanosine diphosphate_G (Homo sapiens) ⟶ G + Guanosine triphosphate_G q (Homo sapiens) + Histamine_Histamine H1 receptor (Homo sapiens)
  • Histamine H1 Receptor Activation: Histamine H1 receptor (Mus musculus)_G q (Mus musculus)_Guanosine diphosphate_G (Mus musculus) ⟶ G + Guanosine triphosphate_G q (Mus musculus) + Histamine_Histamine H1 receptor (Mus musculus)
  • Histamine H1 Receptor Activation: Histamine H1 receptor (Bos taurus)_G q (Bos taurus)_Guanosine diphosphate_G (Bos taurus) ⟶ G + Guanosine triphosphate_G q (Bos taurus) + Histamine_Histamine H1 receptor (Bos taurus)
  • Histamine H1 Receptor Activation: Histamine H1 receptor (Rattus norvegicus)_G q (Rattus norvegicus)_Guanosine diphosphate_G (Rattus norvegicus) ⟶ G + Guanosine triphosphate_G q (Rattus norvegicus) + Histamine_Histamine H1 receptor (Rattus norvegicus)
  • Histidine Metabolism: -Alanine + Adenosine triphosphate + L-Histidine ⟶ Adenosine diphosphate + Carnosine + Phosphate
  • Histidinemia: -Alanine + Adenosine triphosphate + L-Histidine ⟶ Adenosine diphosphate + Carnosine + Phosphate
  • Histidine Metabolism: Imidazole acetol-phosphate + L-Glutamic acid ⟶ L-histidinol phosphate + Oxoglutaric acid
  • Histidine Metabolism: Carnosine + Water ⟶ -Alanine + L-Histidine
  • Histidinemia: Carnosine + Water ⟶ -Alanine + L-Histidine
  • Histidine Metabolism: Carnosine + Water ⟶ -Alanine + L-Histidine
  • Histidine Metabolism: Carnosine + Water ⟶ -Alanine + L-Histidine
  • Histidinemia: Carnosine + Water ⟶ -Alanine + L-Histidine

PharmGKB(0)

33 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ACE, ALOX5, EDN1, POMC, TNK1
Peripheral membrane protein 2 ALOX5, TNK1
cytosol 2 ALOX5, SST
dendrite 1 HRH4
nucleoplasm 1 ALOX5
Cell membrane 5 ACE, CCKBR, HRH4, SELP, TNF
Multi-pass membrane protein 1 CCKBR
Synapse 2 CRH, HRH4
cell surface 2 C3, TNF
Golgi apparatus 1 NPY
Golgi membrane 1 INS
neuronal cell body 2 SST, TNF
Cytoplasm, cytosol 1 ALOX5
Cytoplasmic vesicle, secretory vesicle 1 NTS
Lysosome 1 ACE
endosome 1 ACE
plasma membrane 9 ACE, C3, CCKBR, CSF2, GCG, HRH4, SELP, TNF, TNK1
Membrane 3 ACE, CCKBR, TNK1
axon 1 CCK
extracellular exosome 3 ACE, C3, SELP
extracellular space 16 ACE, ALOX5, C3, CCK, CRH, CSF2, EDN1, GAST, GCG, IL2, INS, NPY, POMC, SELP, SST, TNF
perinuclear region of cytoplasm 1 ALOX5
protein-containing complex 1 C3
intracellular membrane-bounded organelle 3 CCKBR, CSF2, NTS
Single-pass type I membrane protein 2 ACE, SELP
Secreted 15 ACE, C3, CCK, CRH, CSF2, EDN1, GAST, GCG, IL2, INS, NPY, NTS, POMC, SELP, SST
extracellular region 17 ACE, ALOX5, C3, CCK, CRH, CSF2, EDN1, GAST, GCG, IL2, INS, NPY, NTS, POMC, SELP, SST, TNF
basal part of cell 1 EDN1
Nucleus membrane 1 ALOX5
nuclear membrane 1 ALOX5
external side of plasma membrane 3 ACE, SELP, TNF
varicosity 1 CRH
neuronal dense core vesicle lumen 1 CRH
perikaryon 1 CRH
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 1 ALOX5
Membrane raft 1 TNF
GABA-ergic synapse 2 NPY, SST
secretory granule 1 POMC
phagocytic cup 1 TNF
brush border membrane 1 ACE
blood microparticle 1 C3
sperm midpiece 1 ACE
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
endosome lumen 1 INS
basal plasma membrane 1 ACE
platelet dense granule membrane 1 SELP
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 5 ALOX5, C3, GCG, INS, POMC
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 C3, GCG, INS
nuclear matrix 1 ALOX5
axon terminus 1 NTS
transport vesicle 3 EDN1, INS, NTS
azurophil granule lumen 1 C3
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
neuronal dense core vesicle 2 NPY, SST
Nucleus matrix 1 ALOX5
nuclear envelope lumen 1 ALOX5
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
platelet alpha granule membrane 1 SELP
[Glucagon-like peptide 1]: Secreted 1 GCG
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 NPY
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
platelet dense granule lumen 1 SELP
rough endoplasmic reticulum lumen 1 EDN1
Weibel-Palade body 1 EDN1
Nucleus intermembrane space 1 ALOX5
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Mengze Ding, Xiaohan Wei, Changshun Liu, Xiaomei Tan. Mahuang Fuzi Xixin decoction alleviates allergic rhinitis by inhibiting NLRP3/Caspase-1/GSDMD-N-mediated pyroptosis. Journal of ethnopharmacology. 2024 Jun; 327(?):118041. doi: 10.1016/j.jep.2024.118041. [PMID: 38479543]
  • Renata de Souza Sampaio, Anita Oliveira Brito Pereira Bezerra Martins, Lucas Yure Santos da Silva, Dra Renata Torres Pessoa, Jaime Ribeiro-Filho, Gyllyandeson de Araújo Delmondes, Cícero Francisco Bezerra Felipe, Irwin Rose Alencar de Menezes, Marta Regina Kerntopf. Topical Antiedematogenic Activity of the Essential Oil of Psidium brownianum Mart. (OEPB) in Murine Ear Edema Models. Chemistry & biodiversity. 2024 Apr; 21(4):e202400187. doi: 10.1002/cbdv.202400187. [PMID: 38429232]
  • S K Johnsy Sugitha, Raja Venkatesan, R Gladis Latha, Alexandre A Vetcher, Bandar Ali Al-Asbahi, Seong-Cheol Kim. A Study on the Antibacterial, Antispasmodic, Antipyretic, and Anti-Inflammatory Activity of ZnO Nanoparticles Using Leaf Extract from Jasminum sambac (L. Aiton). Molecules (Basel, Switzerland). 2024 Mar; 29(7):. doi: 10.3390/molecules29071464. [PMID: 38611744]
  • Arachchige Maheshika Kumari Jayasinghe, Kirinde Gedara Isuru Sandanuwan Kirindage, Sun-Hyung Kim, Seok Lee, Kil-Nam Kim, Eun-A Kim, Soo-Jin Heo, Ginnae Ahn. Leaves and pseudostems extract of Curcuma longa attenuates immunoglobulin E/bovine serum albumin-stimulated bone marrow-derived cultured mast cell activation and passive cutaneous anaphylaxis in BALB/c mice. Journal of ethnopharmacology. 2024 Mar; 321(?):117529. doi: 10.1016/j.jep.2023.117529. [PMID: 38042384]
  • Jian-Li Huang, Yi-Hua Xu, Xin-Wei Yang, Jie Wang, Yu Zhu, Xian-Bo Wu. Jiawei guomin decoction regulates the degranulation of mast cells in atopic dermatitis mice via the HIS/PAR-2 pathway. Journal of ethnopharmacology. 2024 Mar; 321(?):117485. doi: 10.1016/j.jep.2023.117485. [PMID: 38008276]
  • Zoe Köck, Kilian Schnelle, Margherita Persechino, Simon Umbach, Hannes Schihada, Dovile Januliene, Kristian Parey, Steffen Pockes, Peter Kolb, Volker Dötsch, Arne Möller, Daniel Hilger, Frank Bernhard. Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment. Nature communications. 2024 Feb; 15(1):1831. doi: 10.1038/s41467-024-46096-z. [PMID: 38418462]
  • Haifeng Liu, Yaqin Chen, Yilong Hu, Wenrui Zhang, Hui Zhang, Tianli Su, Juan Wang, Zhongqiong Yin, Xinhong Zhao, Xun Zhou, Lixia Li, Yuanfeng Zou, Yuping Fu, Yingying Zhang, Xu Song. Protective effects of an alcoholic extract of Kaempferia galanga L. rhizome on ethanol-induced gastric ulcer in mice. Journal of ethnopharmacology. 2024 Jan; ?(?):117845. doi: 10.1016/j.jep.2024.117845. [PMID: 38307355]
  • Min Bai, Linna Zhao, Mengya Liu, Runfa Li, Yuping Yang, Yugui Zhang, Xiaomei Yuan, Yarong Li, Yongqiang Duan, Yaorong An, Yingxia Cheng. Deciphering the function of Xiangsha-Liujunzi-Tang in enhancing duodenal mucosal barrier by inhibiting MC/Tryptase/PAR-2 signaling pathway in functional dyspepsia rats. Journal of ethnopharmacology. 2024 Jan; 319(Pt 1):116715. doi: 10.1016/j.jep.2023.116715. [PMID: 37308030]
  • Amit Kaushik, Dewasya P Singh, Mridula Sahu, Ashish Kumar, Pratibha, Pallavi Pandey, Manish K Patel, Debabrata Chanda, Velusamy Sundaresan, Daya N Mani, Ashutosh K Shukla. Protective effect of Achyranthes aspera against compound 48/80, histamine and ovalbumin-induced allergic disorders in murine model. Molecular biology reports. 2024 Jan; 51(1):202. doi: 10.1007/s11033-023-09137-2. [PMID: 38270668]
  • Chen Yang, Jing-Wen Zhang, Jin Qi, Bo-Yang Yu. A novel method for evaluating pseudoallergy based on β-hexosaminidase and its application for traditional Chinese medicine injections. Journal of separation science. 2024 Jan; 47(1):e2300545. doi: 10.1002/jssc.202300545. [PMID: 38234026]
  • Simona Principato, Alvaro Romero, Chow-Yang Lee, Kathleen Campbell, Dong-Hwan Choe, Coby Schal, Zachary DeVries. Histamine excretion in common indoor and hematophagous arthropods. Journal of medical entomology. 2023 11; 60(6):1269-1277. doi: 10.1093/jme/tjad103. [PMID: 37619246]
  • Maria Gabriely de Lima Silva, Lucas Yure Santos da Silva, Renata Torres Pessoa, Maria Rayane Correia de Oliveira, Francisco Lucas Alves Batista, Isabel Sousa Alcantara, Anita Oliveira Brito Pereira Bezerra Martins, Jaime Ribeiro-Filho, Henrique Coutinho, Irwin Rose Alencar de Menezes. Antiedematogenic and analgesic activities of abietic acid in mice. Chemistry & biodiversity. 2023 Oct; ?(?):e202300906. doi: 10.1002/cbdv.202300906. [PMID: 37795905]
  • Doaa R I Abdel-Gawad, Marwa A Ibrahim, Usama K Moawad, Shaimaa Kamel, Hossny A El-Banna, Ahmed H El-Banna, Walid Hamdy Hassan, Fatma I Abo El-Ela. Effectiveness of natural biomaterials in the protection and healing of experimentally induced gastric mucosa Ulcer in rats. Molecular biology reports. 2023 Sep; ?(?):. doi: 10.1007/s11033-023-08776-9. [PMID: 37741810]
  • Bruno Anderson Fernandes da Silva, Renata Torres Pessoa, Roger Henrique Sousa da Costa, Maria Rayane Correia de Oliveira, Andreza Guedes Barbosa Ramos, Maria Gabriely de Lima Silva, Lucas Yure Santos da Silva, Cassio Rocha Medeiros, Sloana Giesta Lemos Florencio, Jaime Ribeiro-Filho, Henrique Douglas Melo Coutinho, António Raposo, Sunghoon Yoo, Heesup Han, Irwin Rose Alencar de Menezes, Lucindo José Quintans Júnior. Evaluation of the antiedematogenic and anti-inflammatory properties of Ximenia americana L. (Olacaceae) bark extract in experimental models of inflammation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Aug; 166(?):115249. doi: 10.1016/j.biopha.2023.115249. [PMID: 37597323]
  • Johnalyn M Gordon, Richard G Santangelo, Maria A González-Morales, Mark Menechella, Coby Schal, Zachary C DeVries. Spatial distribution of histamine in bed bug-infested homes. The Science of the total environment. 2023 Jul; 880(?):163180. doi: 10.1016/j.scitotenv.2023.163180. [PMID: 37001661]
  • Karelle Kouam Yacine Madjo, Marius Mbiantcha, Linda Zenab Njoya Fagni, Vanessa Mba Matah Marthe, Elvira Azanze Ngoufack, Gonzal Eric Tsafack, Stephanie Flore Djuichou Nguemnang, Carine Flore Adjouzem, Gilbert Ateufack. Gastroprotective and ulcer healing effects of Nauclea pobeguinii (Rubiaceae) on experimentally induced gastric ulcers in male Wistar rats. Journal of complementary & integrative medicine. 2023 Jun; ?(?):. doi: 10.1515/jcim-2023-0024. [PMID: 37382892]
  • Karen Rodríguez-Núñez, Alejandra Cortés-Monroy, Marcela Serey, Yunus Ensari, Mehdi D Davari, Claudia Bernal, Ronny Martinez. Modulating Substrate Specificity of Rhizobium sp. Histamine Dehydrogenase through Protein Engineering for Food Quality Applications. Molecules (Basel, Switzerland). 2023 Apr; 28(9):. doi: 10.3390/molecules28093748. [PMID: 37175158]
  • Si-Jia Liu, Jun-Tong Liu, Ji-Quan Li, Cheng-Cheng Wang, Miao Yu, Zhi-Qiang Guan, Lie Wang, Tie-Ming Ma. [Effect of acupuncture pretreatment of "Quchi"(LI11) and "Xuehai" (SP10) on mast cells and IL-33/ST2 in rats with urticaria]. Zhen ci yan jiu = Acupuncture research. 2023 Apr; 48(4):311-6. doi: 10.13702/j.1000-0607.20211282. [PMID: 37186193]
  • Audrey Siew Foong Kow, Leng Wei Khoo, Ji Wei Tan, Faridah Abas, Ming-Tatt Lee, Daud Ahmad Israf, Khozirah Shaari, Chau Ling Tham. Clinacanthus nutans aqueous leaves extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway. Journal of ethnopharmacology. 2023 Mar; 303(?):116003. doi: 10.1016/j.jep.2022.116003. [PMID: 36464074]
  • Guizhou Hu, Lu Wang, Xinqi Li, Jin Qi. Rapidly and accurately screening histidine decarboxylase inhibitors from Radix Paeoniae alba using ultrafiltration-high performance liquid chromatography/mass spectrometry combined with enzyme channel blocking and directional enrichment technique. Journal of chromatography. A. 2023 Feb; 1693(?):463859. doi: 10.1016/j.chroma.2023.463859. [PMID: 36868086]
  • Niuniu Yang, Haifeng Shao, Jialin Deng, Yan Yang, Zongxiang Tang, Guanyi Wu, Yanqing Liu. Dictamnine ameliorates chronic itch in DNFB-induced atopic dermatitis mice via inhibiting MrgprA3. Biochemical pharmacology. 2023 02; 208(?):115368. doi: 10.1016/j.bcp.2022.115368. [PMID: 36493846]
  • Meshack Antwi-Adjei, Ernest Obese, Emmanuel Awiintig Adakudugu, Isaac Tabiri Henneh, Robert Peter Biney, Benjamin Aboagye, Benjamin Amoani, Daniel Anokwah, Elvis Ofori Ameyaw. Modulating Effects of the Hydroethanolic Leaf Extract of Persicaria lanigera R. Br. Soják (Polygonaceae) against Acute Inflammation. TheScientificWorldJournal. 2023; 2023(?):5567410. doi: 10.1155/2023/5567410. [PMID: 37469933]
  • Makoto Yasuda, Yukinori Tanaka, Kanan Bando, Shunji Sugawara, Kentaro Mizuta. Lipopolysaccharide Priming Exacerbates Anaphylatoxin C5a-Induced Anaphylaxis in Mice. Biological & pharmaceutical bulletin. 2023; 46(3):432-439. doi: 10.1248/bpb.b22-00766. [PMID: 36858572]
  • Anca D Buzoianu, Aruna Sharma, Dafin F Muresanu, Lianyuan Feng, Hongyun Huang, Lin Chen, Z Ryan Tian, Ala Nozari, José Vicente Lafuente, Lars Wiklund, Hari Shanker Sharma. Nanodelivery of Histamine H3/H4 Receptor Modulators BF-2649 and Clobenpropit with Antibodies to Amyloid Beta Peptide in Combination with Alpha Synuclein Reduces Brain Pathology in Parkinson's Disease. Advances in neurobiology. 2023; 32(?):55-96. doi: 10.1007/978-3-031-32997-5_2. [PMID: 37480459]
  • Haoyun Bai, Zhuoyin Xue, Wen Zhang, Chaohua Feng, Zhenqi Zhou, Shiling Hu, Yongjing Zhang, Qiaohong Qin, Yuanyuan Wu, Xiuzhen Sun, Yuhan Zhou, Nan Wang. α-Asarone alleviates allergic asthma by stabilizing mast cells through inhibition of ERK/JAK2-STAT3 pathway. BioFactors (Oxford, England). 2023 Jan; 49(1):140-152. doi: 10.1002/biof.1879. [PMID: 35861676]
  • Sudip Gaire, Simona Principato, Coby Schal, Zachary C DeVries. Histamine Excretion by the Common Bed Bug (Hemiptera: Cimicidae). Journal of medical entomology. 2022 11; 59(6):1898-1904. doi: 10.1093/jme/tjac131. [PMID: 36086827]
  • Jesper Säfholm, Willem Abma, Lora G Bankova, Joshua A Boyce, Mamdoh Al-Ameri, Ann-Charlotte Orre, Craig E Wheelock, Sven-Erik Dahlén, Mikael Adner. Cysteinyl-maresin 3 inhibits IL-13 induced airway hyperresponsiveness through alternative activation of the CysLT1 receptor. European journal of pharmacology. 2022 Nov; 934(?):175257. doi: 10.1016/j.ejphar.2022.175257. [PMID: 36116518]
  • Xue Mei Fang, Ying Liu, Ji Wang, Xin Zhang, Lei Wang, Li Zhang, Hong Ping Zhang, Lei Liu, Dan Huang, Dan Liu, Ke Deng, Feng Ming Luo, Hua Jing Wan, Wei Min Li, Gang Wang, Brian G Oliver. Endogenous Adenosine 5'-Monophosphate, But Not Acetylcholine or Histamine, is Associated with Asthma Control, Quality of Life, and Exacerbations. Lung. 2022 10; 200(5):579-589. doi: 10.1007/s00408-022-00570-x. [PMID: 36156139]
  • Yue Ma, Shu Li, Hongxi Yang, Yuan Zhang, Huiping Li, Lihui Zhou, Jing Lin, Yanchun Chen, Yabing Hou, Xinyu Zhang, Tong Liu, Xin Zhou, Yaogang Wang. Acid suppressants use and risk of atherosclerotic cardiovascular disease in middle-aged and older adults. Atherosclerosis. 2022 10; 358(?):47-54. doi: 10.1016/j.atherosclerosis.2022.09.001. [PMID: 36113328]
  • Menglu Yang, Haakon K Fjærvoll, Ketil A Fjærvoll, Nicholas H Wang, Tor P Utheim, Charles N Serhan, Darlene A Dartt. Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators. Scientific reports. 2022 09; 12(1):16305. doi: 10.1038/s41598-022-20177-9. [PMID: 36175572]
  • Wen Yan Huang, Sang Hoon Lee, Seong Ju Oh, Hyeock Yoon, Jeong Hoon Pan, Inhye Jeong, Mi Jeong Kim, Bok Kyung Han, Jae Kyeom Kim, Eui-Cheol Shin, Young Jun Kim. Canavalia gladiata Pod Extract Mitigates Ovalbumin-Induced Asthma Onset in Male BALB/c Mice via Suppression of MAPK. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196317. [PMID: 36234854]
  • Lindaiane B R Dantas, Isabel S Alcântara, Cícero Pedro S Júnior, Maria Rayane C de Oliveira, Anita O B P B Martins, Ticiano M Dantas, Jaime Ribeiro-Filho, Henrique Douglas M Coutinho, Fabíolla R S Passos, Lucindo J Quintans-Júnior, Jackson Roberto G S Almeida, Natália Cruz-Martins, Bonglee Kim, Irwin Rose Alencar de Menezes. In vivo and in silico anti-inflammatory properties of the sesquiterpene valencene. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Sep; 153(?):113478. doi: 10.1016/j.biopha.2022.113478. [PMID: 36076580]
  • Hye Jin Kim, Hyun-Kyung Song, Sun Haeng Park, Seol Jang, Ki-Sun Park, Kwang Hoon Song, Sang Kook Lee, Taesoo Kim. Terminalia chebula Retz. extract ameliorates the symptoms of atopic dermatitis by regulating anti-inflammatory factors in vivo and suppressing STAT1/3 and NF-ĸB signaling in vitro. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Sep; 104(?):154318. doi: 10.1016/j.phymed.2022.154318. [PMID: 35830757]
  • Makoto Matsushita, Kazutoshi Fujita, Koji Hatano, Takuji Hayashi, Hisako Kayama, Daisuke Motooka, Hiroaki Hase, Akinaru Yamamoto, Toshihiko Uemura, Gaku Yamamichi, Eisuke Tomiyama, Yoko Koh, Taigo Kato, Atsunari Kawashima, Motohide Uemura, Satoshi Nojima, Ryoichi Imamura, Aysha Mubeen, George J Netto, Kazutake Tsujikawa, Shota Nakamura, Kiyoshi Takeda, Eiichi Morii, Norio Nonomura. High-fat diet promotes prostate cancer growth through histamine signaling. International journal of cancer. 2022 08; 151(4):623-636. doi: 10.1002/ijc.34028. [PMID: 35403732]
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