palmitoyl-CoA (BioDeep_00001868767)

Main id: BioDeep_00000004146

 

Volatile Flavor Compounds


代谢物信息卡片


palmitoyl-CoA

化学式: C37H66N7O17P3S (1005.3448576)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O
InChI: InChI=1S/C37H66N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44/h24-26,30-32,36,47-48H,4-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52)/t26-,30-,31-,32+,36-/m1/s1

描述信息

A long-chain fatty acyl-CoA resulting from the formal condensation of the carboxy group of hexadecanoic acid with the thiol group of coenzyme A.
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同义名列表

2 个代谢物同义名

palmitoyl-CoA; Palmitoyl-CoA



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(1)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • M Kerr, K M J H Dennis, C A Carr, W Fuller, G Berridge, S Rohling, C L Aitken, C Lopez, R Fischer, J J Miller, K Clarke, D J Tyler, L C Heather. Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischemia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 08; 35(8):e21765. doi: 10.1096/fj.202100394r. [PMID: 34318967]
  • Henver S Brunetta, Heather L Petrick, Bayley Vachon, Everson A Nunes, Graham P Holloway. Insulin rapidly increases skeletal muscle mitochondrial ADP sensitivity in the absence of a high lipid environment. The Biochemical journal. 2021 07; 478(13):2539-2553. doi: 10.1042/bcj20210264. [PMID: 34129667]
  • Lucas M O'Neill, Chang-An Guo, Fang Ding, Yar Xin Phang, Zhaojin Liu, Sohel Shamsuzzaman, James M Ntambi. Stearoyl-CoA Desaturase-2 in Murine Development, Metabolism, and Disease. International journal of molecular sciences. 2020 Nov; 21(22):. doi: 10.3390/ijms21228619. [PMID: 33207603]
  • Xiaolei Pan, Zheng Fan, Lei Chen, Chang Liu, Fang Bai, Yu Wei, Zhenyang Tian, Yuanyuan Dong, Jing Shi, Hao Chen, Yongxin Jin, Zhihui Cheng, Shouguang Jin, Jianping Lin, Weihui Wu. PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids. Nucleic acids research. 2020 06; 48(11):5967-5985. doi: 10.1093/nar/gkaa377. [PMID: 32406921]
  • Pierre-Emmanuel Tardo-Dino, Julianne Touron, Stéphane Baugé, Stéphanie Bourdon, Nathalie Koulmann, Alexandra Malgoyre. The effect of a physiological increase in temperature on mitochondrial fatty acid oxidation in rat myofibers. Journal of applied physiology (Bethesda, Md. : 1985). 2019 08; 127(2):312-319. doi: 10.1152/japplphysiol.00652.2018. [PMID: 31161881]
  • James John Asciolla, Kalpana Rajanala, Marilyn D Resh. In Vitro Analysis of Hedgehog Acyltransferase and Porcupine Fatty Acyltransferase Activities. Methods in molecular biology (Clifton, N.J.). 2019; 2009(?):243-255. doi: 10.1007/978-1-4939-9532-5_19. [PMID: 31152409]
  • Carine Lindquist, Bodil Bjørndal, Hege G Bakke, Grete Slettom, Marie Karoliussen, Arild C Rustan, G Hege Thoresen, Jon Skorve, Ottar K Nygård, Rolf Kristian Berge. A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats. PloS one. 2019; 14(9):e0222558. doi: 10.1371/journal.pone.0222558. [PMID: 31550253]
  • Sonia Cortassa, Steven J Sollott, Miguel A Aon. Mitochondrial respiration and ROS emission during β-oxidation in the heart: An experimental-computational study. PLoS computational biology. 2017 Jun; 13(6):e1005588. doi: 10.1371/journal.pcbi.1005588. [PMID: 28598967]
  • Paula M Miotto, Gregory R Steinberg, Graham P Holloway. Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise. The Biochemical journal. 2017 02; 474(4):557-569. doi: 10.1042/bcj20160913. [PMID: 27941154]
  • Rongsui Gao, Defeng Li, Yuan Lin, Jingxia Lin, Xiaoyun Xia, Hui Wang, Lijun Bi, Jun Zhu, Bachar Hassan, Shihua Wang, Youjun Feng. Structural and Functional Characterization of the FadR Regulatory Protein from Vibrio alginolyticus. Frontiers in cellular and infection microbiology. 2017; 7(?):513. doi: 10.3389/fcimb.2017.00513. [PMID: 29312893]
  • Melissa K Ritchie, Lynnette C Johnson, Jill E Clodfelter, Charles W Pemble, Brian E Fulp, Cristina M Furdui, Steven J Kridel, W Todd Lowther. Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE. The Journal of biological chemistry. 2016 Feb; 291(7):3520-30. doi: 10.1074/jbc.m115.702597. [PMID: 26663084]
  • Eric Soupene, Joseph Kao, Daniel H Cheng, Derek Wang, Alexander L Greninger, Giselle M Knudsen, Joseph L DeRisi, Frans A Kuypers. Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA. Journal of lipid research. 2016 Feb; 57(2):288-98. doi: 10.1194/jlr.m065003. [PMID: 26621918]
  • David R Colquhoun, Alexey E Lyashkov, Ceereena Ubaida Mohien, Veronica N Aquino, Brandon T Bullock, Rhoel R Dinglasan, Brian J Agnew, David R M Graham. Bioorthogonal mimetics of palmitoyl-CoA and myristoyl-CoA and their subsequent isolation by click chemistry and characterization by mass spectrometry reveal novel acylated host-proteins modified by HIV-1 infection. Proteomics. 2015 Jun; 15(12):2066-77. doi: 10.1002/pmic.201500063. [PMID: 25914232]
  • Demidmaa Tuvdendorj, Xiao-jun Zhang, David L Chinkes, Lijian Wang, Zhanpin Wu, Noe A Rodriguez, David N Herndon, Robert R Wolfe. Triglycerides produced in the livers of fasting rabbits are predominantly stored as opposed to secreted into the plasma. Metabolism: clinical and experimental. 2015 May; 64(5):580-7. doi: 10.1016/j.metabol.2015.01.002. [PMID: 25682063]
  • Jessica Seeßle, Gerhard Liebisch, Gerd Schmitz, Wolfgang Stremmel, Walee Chamulitrat. Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis. Biochimica et biophysica acta. 2015 May; 1851(5):549-65. doi: 10.1016/j.bbalip.2015.01.004. [PMID: 25603556]
  • Andrew J Worth, Sankha S Basu, Nathaniel W Snyder, Clementina Mesaros, Ian A Blair. Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels. The Journal of biological chemistry. 2014 Sep; 289(39):26895-26903. doi: 10.1074/jbc.m114.591354. [PMID: 25122772]
  • Franziska Dittrich-Domergue, Jérôme Joubès, Patrick Moreau, René Lessire, Sten Stymne, Frédéric Domergue. The bifunctional protein TtFARAT from Tetrahymena thermophila catalyzes the formation of both precursors required to initiate ether lipid biosynthesis. The Journal of biological chemistry. 2014 Aug; 289(32):21984-94. doi: 10.1074/jbc.m114.579318. [PMID: 24917677]
  • Marie-Soleil Beaudoin, Christopher G R Perry, Alicia M Arkell, Adrian Chabowski, Jeremy A Simpson, David C Wright, Graham P Holloway. Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats. The Journal of physiology. 2014 Jun; 592(12):2519-33. doi: 10.1113/jphysiol.2013.270538. [PMID: 24639481]
  • Madhumitha Balanarasimha, Andrea M Davis, Frances L Soman, S Dean Rider, Heather A Hostetler. Ligand-regulated heterodimerization of peroxisome proliferator-activated receptor α with liver X receptor α. Biochemistry. 2014 Apr; 53(16):2632-43. doi: 10.1021/bi401679y. [PMID: 24713062]
  • Janos Kerner, Paul E Minkler, Edward J Lesnefsky, Charles L Hoppel. Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation. The Journal of biological chemistry. 2014 Apr; 289(14):10223-34. doi: 10.1074/jbc.m113.524314. [PMID: 24558043]
  • Yi Yu, Chris R J Carter, Nermeen Youssef, Jason R B Dyck, Peter E Light. Intracellular long-chain acyl CoAs activate TRPV1 channels. PloS one. 2014; 9(5):e96597. doi: 10.1371/journal.pone.0096597. [PMID: 24798548]
  • Sarah Brice Russo, Rotem Tidhar, Anthony H Futerman, L Ashley Cowart. Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties. The Journal of biological chemistry. 2013 May; 288(19):13397-409. doi: 10.1074/jbc.m112.428185. [PMID: 23530041]
  • E Alefishat, S P H Alexander, V Ralevic. Antagonism of P2Y1-induced vasorelaxation by acyl CoA: a critical role for palmitate and 3'-phosphate. British journal of pharmacology. 2013 Apr; 168(8):1911-22. doi: 10.1111/bph.12086. [PMID: 23215951]
  • Xiao-jun Zhang, Lijian Wang, Demidmaa Tuvdendorj, Zhanpin Wu, Noe A Rodriguez, David N Herndon, Robert R Wolfe. Acute hyperinsulinemia and reduced plasma free fatty acid levels decrease intramuscular triglyceride synthesis. Metabolism: clinical and experimental. 2013 Jan; 62(1):44-51. doi: 10.1016/j.metabol.2012.06.002. [PMID: 22898252]
  • Sung Ho Moon, Christopher M Jenkins, Michael A Kiebish, Harold F Sims, David J Mancuso, Richard W Gross. Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release. The Journal of biological chemistry. 2012 Aug; 287(35):29837-50. doi: 10.1074/jbc.m112.373654. [PMID: 22778252]
  • Benjamin C Jennings, Maurine E Linder. DHHC protein S-acyltransferases use similar ping-pong kinetic mechanisms but display different acyl-CoA specificities. The Journal of biological chemistry. 2012 Mar; 287(10):7236-45. doi: 10.1074/jbc.m111.337246. [PMID: 22247542]
  • Xiao-Jun Zhang, Noe A Rodriguez, Lijian Wang, Demidmaa Tuvdendorj, Zhanpin Wu, Alai Tan, David N Herndon, Robert R Wolfe. Measurement of precursor enrichment for calculating intramuscular triglyceride fractional synthetic rate. Journal of lipid research. 2012 Jan; 53(1):119-25. doi: 10.1194/jlr.m019901. [PMID: 21934122]
  • Eri Oyanagi, Hiromi Yano, Masataka Uchida, Kozo Utsumi, Junzo Sasaki. Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acid stress. Biochemical and biophysical research communications. 2011 Aug; 412(1):61-7. doi: 10.1016/j.bbrc.2011.07.039. [PMID: 21791201]
  • Christopher A Haynes, Jeremy C Allegood, Elaine W Wang, Samuel L Kelly, M Cameron Sullards, Alfred H Merrill. Factors to consider in using [U-C]palmitate for analysis of sphingolipid biosynthesis by tandem mass spectrometry. Journal of lipid research. 2011 Aug; 52(8):1583-94. doi: 10.1194/jlr.d015586. [PMID: 21586681]
  • Sergei A Novgorodov, Bill X Wu, Tatyana I Gudz, Jacek Bielawski, Tatiana V Ovchinnikova, Yusuf A Hannun, Lina M Obeid. Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA. The Journal of biological chemistry. 2011 Jul; 286(28):25352-62. doi: 10.1074/jbc.m110.214866. [PMID: 21613224]
  • Christopher M Jenkins, Jingyue Yang, Harold F Sims, Richard W Gross. Reversible high affinity inhibition of phosphofructokinase-1 by acyl-CoA: a mechanism integrating glycolytic flux with lipid metabolism. The Journal of biological chemistry. 2011 Apr; 286(14):11937-50. doi: 10.1074/jbc.m110.203661. [PMID: 21258134]
  • Natasha H Banke, Adam R Wende, Teresa C Leone, J Michael O'Donnell, E Dale Abel, Daniel P Kelly, E Douglas Lewandowski. Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha. Circulation research. 2010 Jul; 107(2):233-41. doi: 10.1161/circresaha.110.221713. [PMID: 20522803]
  • Xiao-jun Zhang, David L Chinkes, Zhanpin Wu, David N Herndon, Robert R Wolfe. The synthetic rate of muscle triglyceride but not phospholipid is increased in obese rabbits. Metabolism: clinical and experimental. 2009 Nov; 58(11):1649-56. doi: 10.1016/j.metabol.2009.05.021. [PMID: 19608209]
  • Seigo Korematsu, Yujiro Kosugi, Toshihide Kumamoto, Seiji Yamaguchi, Tatsuro Izumi. Novel mutation of early, perinatal-onset, myopathic-type very-long-chain acyl-CoA dehydrogenase deficiency. Pediatric neurology. 2009 Aug; 41(2):151-3. doi: 10.1016/j.pediatrneurol.2009.02.020. [PMID: 19589468]
  • Markus F Rütti, Stéphane Richard, Anke Penno, Arnold von Eckardstein, Thorsten Hornemann. An improved method to determine serine palmitoyltransferase activity. Journal of lipid research. 2009 Jun; 50(6):1237-44. doi: 10.1194/jlr.d900001-jlr200. [PMID: 19181628]
  • Go Tajima, Nobuo Sakura, Kenichiro Shirao, Satoshi Okada, Miyuki Tsumura, Yutaka Nishimura, Hiroaki Ono, Yuki Hasegawa, Ikue Hata, Etsuo Naito, Seiji Yamaguchi, Yosuke Shigematsu, Masao Kobayashi. Development of a new enzymatic diagnosis method for very-long-chain Acyl-CoA dehydrogenase deficiency by detecting 2-hexadecenoyl-CoA production and its application in tandem mass spectrometry-based selective screening and newborn screening in Japan. Pediatric research. 2008 Dec; 64(6):667-72. doi: 10.1203/pdr.0b013e318187cc44. [PMID: 18670371]
  • Heather A Hostetler, Lindsay R Syler, Lindy N Hall, Guan Zhu, Friedhelm Schroeder, Ann B Kier. A novel high-throughput screening assay for putative antidiabetic agents through PPARalpha interactions. Journal of biomolecular screening. 2008 Oct; 13(9):855-61. doi: 10.1177/1087057108323127. [PMID: 18812576]
  • Muhammad A Abdul-Ghani, Florian L Muller, Yuhong Liu, Alberto O Chavez, Bogdan Balas, Pengou Zuo, Zhi Chang, Devjit Tripathy, Rucha Jani, Marjorie Molina-Carrion, Adriana Monroy, Franco Folli, Holly Van Remmen, Ralph A DeFronzo. Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance. American journal of physiology. Endocrinology and metabolism. 2008 Sep; 295(3):E678-85. doi: 10.1152/ajpendo.90287.2008. [PMID: 18593850]
  • Rob Stierum, Ana Conesa, Wilbert Heijne, Ben van Ommen, Karin Junker, Mary P Scott, Roger J Price, Clive Meredith, Brian G Lake, John Groten. Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Aug; 46(8):2616-28. doi: 10.1016/j.fct.2008.04.019. [PMID: 18539377]
  • Hiromutsu Tominaga, Hideki Katoh, Keiichi Odagiri, Yasuyo Takeuchi, Hirotaka Kawashima, Masao Saotome, Tsuyoshi Urushida, Hiroshi Satoh, Hideharu Hayashi. Different effects of palmitoyl-L-carnitine and palmitoyl-CoA on mitochondrial function in rat ventricular myocytes. American journal of physiology. Heart and circulatory physiology. 2008 Jul; 295(1):H105-12. doi: 10.1152/ajpheart.01307.2007. [PMID: 18469143]
  • Sonja Primassin, Frank Ter Veld, Ertan Mayatepek, Ute Spiekerkoetter. Carnitine supplementation induces acylcarnitine production in tissues of very long-chain acyl-CoA dehydrogenase-deficient mice, without replenishing low free carnitine. Pediatric research. 2008 Jun; 63(6):632-7. doi: 10.1203/pdr.0b013e31816ff6f0. [PMID: 18317232]
  • Diego F G Vallejo, J Raúl Grigera, Marcelo D Costabel. A hydrophobic loop in acyl-CoA binding protein is functionally important for binding to palmitoyl-coenzyme A: a molecular dynamics study. International journal of biological macromolecules. 2008 Apr; 42(3):271-7. doi: 10.1016/j.ijbiomac.2007.12.003. [PMID: 18242688]
  • Ellen Aasum, Ahmed Murtaz Khalid, Oddrun Anita Gudbrandsen, Ole-Jakob How, Rolf K Berge, Terje S Larsen. Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice. Journal of molecular and cellular cardiology. 2008 Jan; 44(1):201-9. doi: 10.1016/j.yjmcc.2007.08.020. [PMID: 17931655]
  • David M Selva, Kevin N Hogeveen, Sheila M Innis, Geoffrey L Hammond. Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene. The Journal of clinical investigation. 2007 Dec; 117(12):3979-87. doi: 10.1172/jci32249. [PMID: 17992261]
  • Olga Jáuregui, Adriana Y Sierra, Patricia Carrasco, Esther Gratacós, Fausto G Hegardt, Núria Casals. A new LC-ESI-MS/MS method to measure long-chain acylcarnitine levels in cultured cells. Analytica chimica acta. 2007 Sep; 599(1):1-6. doi: 10.1016/j.aca.2007.07.066. [PMID: 17765057]
  • C Cowles, A Mally, J K Chipman. Different mechanisms of modulation of gap junction communication by non-genotoxic carcinogens in rat liver in vivo. Toxicology. 2007 Aug; 238(1):49-59. doi: 10.1016/j.tox.2007.05.027. [PMID: 17624652]
  • Tomoaki Toyama, Naomi Kudo, Yasuhide Hibino, Atsushi Mitsumoto, Masazumi Nishikawa, Yoichi Kawashima. Effects of pioglitazone on stearoyl-CoA desaturase in obese Zucker fa/fa rats. Journal of pharmacological sciences. 2007 Jun; 104(2):137-45. doi: 10.1254/jphs.fp0060997. [PMID: 17538229]
  • S Wein, J Ukropec, D Gasperíková, I Klimes, E Seböková. Concerted action of leptin in regulation of fatty acid oxidation in skeletal muscle and liver. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 2007 Apr; 115(4):244-51. doi: 10.1055/s-2007-956166. [PMID: 17479441]
  • Clinton R Bruce, Camilla Brolin, Nigel Turner, Mark E Cleasby, Feike R van der Leij, Gregory J Cooney, Edward W Kraegen. Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification. American journal of physiology. Endocrinology and metabolism. 2007 Apr; 292(4):E1231-7. doi: 10.1152/ajpendo.00561.2006. [PMID: 17179390]
  • Sarah M Turpin, Graeme I Lancaster, Ian Darby, Mark A Febbraio, Matthew J Watt. Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance. American journal of physiology. Endocrinology and metabolism. 2006 Dec; 291(6):E1341-50. doi: 10.1152/ajpendo.00095.2006. [PMID: 16849630]
  • Michaela Liebig, Ina Schymik, Martina Mueller, Udo Wendel, Ertan Mayatepek, Jos Ruiter, Arnold W Strauss, Ronald J A Wanders, Ute Spiekerkoetter. Neonatal screening for very long-chain acyl-coA dehydrogenase deficiency: enzymatic and molecular evaluation of neonates with elevated C14:1-carnitine levels. Pediatrics. 2006 Sep; 118(3):1065-9. doi: 10.1542/peds.2006-0666. [PMID: 16950999]
  • Bin Zeng, Xiaomin Cai, Guan Zhu. Functional characterization of a fatty acyl-CoA-binding protein (ACBP) from the apicomplexan Cryptosporidium parvum. Microbiology (Reading, England). 2006 Aug; 152(Pt 8):2355-2363. doi: 10.1099/mic.0.28944-0. [PMID: 16849800]
  • Ronald N Cortright, Kimberly M Sandhoff, Jessica L Basilio, Jason R Berggren, Robert C Hickner, Matthew W Hulver, G Lynis Dohm, Joseph A Houmard. Skeletal muscle fat oxidation is increased in African-American and white women after 10 days of endurance exercise training. Obesity (Silver Spring, Md.). 2006 Jul; 14(7):1201-10. doi: 10.1038/oby.2006.137. [PMID: 16899801]
  • Maria José Caballero, Germán Gallardo, Lidia Robaina, Daniel Montero, Antonio Fernández, Marisol Izquierdo. Vegetable lipid sources affect in vitro biosynthesis of triacylglycerols and phospholipids in the intestine of sea bream (Sparus aurata). The British journal of nutrition. 2006 Mar; 95(3):448-54. doi: 10.1079/bjn20051529. [PMID: 16512929]
  • Liping Hu, Jude T Deeney, Christopher J Nolan, Marie-Line Peyot, Ada Ao, Ann Marie Richard, Esthere Luc, Nils J Faergeman, Jens Knudsen, Wen Guo, Maria Sorhede-Winzell, Marc Prentki, Barbara E Corkey. Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes. American journal of physiology. Endocrinology and metabolism. 2005 Dec; 289(6):E1085-92. doi: 10.1152/ajpendo.00210.2005. [PMID: 16091387]
  • M D Voss, A Beha, N Tennagels, G Tschank, A W Herling, M Quint, M Gerl, C Metz-Weidmann, G Haun, M Korn. Gene expression profiling in skeletal muscle of Zucker diabetic fatty rats: implications for a role of stearoyl-CoA desaturase 1 in insulin resistance. Diabetologia. 2005 Dec; 48(12):2622-30. doi: 10.1007/s00125-005-0025-2. [PMID: 16284748]
  • Jingyue Yang, Beverly Gibson, Jacqueline Snider, Christopher M Jenkins, Xianlin Han, Richard W Gross. Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance. Biochemistry. 2005 Sep; 44(35):11903-12. doi: 10.1021/bi0508082. [PMID: 16128592]
  • D S Rubink, W W Winder. Effect of phosphorylation by AMP-activated protein kinase on palmitoyl-CoA inhibition of skeletal muscle acetyl-CoA carboxylase. Journal of applied physiology (Bethesda, Md. : 1985). 2005 Apr; 98(4):1221-7. doi: 10.1152/japplphysiol.00621.2004. [PMID: 15579580]
  • Ingunn Stubhaug, Livar Frøyland, Bente E Torstensen. beta-Oxidation capacity of red and white muscle and liver in Atlantic salmon (Salmo salar L.)--effects of increasing dietary rapeseed oil and olive oil to replace capelin oil. Lipids. 2005 Jan; 40(1):39-47. doi: 10.1007/s11745-005-1358-4. [PMID: 15825829]
  • Masaki Fukata, Yuko Fukata, Hillel Adesnik, Roger A Nicoll, David S Bredt. Identification of PSD-95 palmitoylating enzymes. Neuron. 2004 Dec; 44(6):987-96. doi: 10.1016/j.neuron.2004.12.005. [PMID: 15603741]
  • Aron Allen, Jae Kwagh, Jie Fang, Charles A Stanley, Thomas J Smith. Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation. Biochemistry. 2004 Nov; 43(45):14431-43. doi: 10.1021/bi048817i. [PMID: 15533048]
  • Charlotta S Olofsson, Albert Salehi, Cecilia Holm, Patrik Rorsman. Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells. The Journal of physiology. 2004 Jun; 557(Pt 3):935-48. doi: 10.1113/jphysiol.2004.066258. [PMID: 15090611]
  • Jocelyn E Manning Fox, Colin G Nichols, Peter E Light. Activation of adenosine triphosphate-sensitive potassium channels by acyl coenzyme A esters involves multiple phosphatidylinositol 4,5-bisphosphate-interacting residues. Molecular endocrinology (Baltimore, Md.). 2004 Mar; 18(3):679-86. doi: 10.1210/me.2003-0431. [PMID: 14694085]
  • R Crescenzo, D Mainieri, G Solinas, J P Montani, J Seydoux, G Liverini, S Iossa, A G Dulloo. Skeletal muscle mitochondrial oxidative capacity and uncoupling protein 3 are differently influenced by semistarvation and refeeding. FEBS letters. 2003 Jun; 544(1-3):138-42. doi: 10.1016/s0014-5793(03)00491-5. [PMID: 12782304]
  • Dominic A Nanton, Santosh P Lall, Neil W Ross, Mary A McNiven. Effect of dietary lipid level on fatty acid beta-oxidation and lipid composition in various tissues of haddock, Melanogrammus aeglefinus L. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2003 May; 135(1):95-108. doi: 10.1016/s1096-4959(03)00052-6. [PMID: 12781977]
  • Alison L Clarke, Steven Petrou, John V Walsh, Joshua J Singer. Site of action of fatty acids and other charged lipids on BKCa channels from arterial smooth muscle cells. American journal of physiology. Cell physiology. 2003 Mar; 284(3):C607-19. doi: 10.1152/ajpcell.00364.2002. [PMID: 12409285]
  • Christiane Kleuss, Eberhard Krause. Galpha(s) is palmitoylated at the N-terminal glycine. The EMBO journal. 2003 Feb; 22(4):826-32. doi: 10.1093/emboj/cdg095. [PMID: 12574119]
  • Jan Modregger, Anne A Schmidt, Brigitte Ritter, Wieland B Huttner, Markus Plomann. Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. The Journal of biological chemistry. 2003 Feb; 278(6):4160-7. doi: 10.1074/jbc.m208568200. [PMID: 12456676]
  • T Furuno, T Kanno, K Arita, M Asami, T Utsumi, Y Doi, M Inoue, K Utsumi. Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition. Biochemical pharmacology. 2001 Oct; 62(8):1037-46. doi: 10.1016/s0006-2952(01)00745-6. [PMID: 11597572]
  • Y X Wang, E J Kauffman, J E Duex, L S Weisman. Fusion of docked membranes requires the armadillo repeat protein Vac8p. The Journal of biological chemistry. 2001 Sep; 276(37):35133-40. doi: 10.1074/jbc.m103937200. [PMID: 11441010]
  • K Imai, N Kudo, M Koyam, A Shirahata, Y Kawashim. Effects of dehydroepiandrosterone on oleic acid formation in the liver of rats, mice and guinea pigs. Japanese journal of pharmacology. 2001 Aug; 86(4):437-47. doi: 10.1254/jjp.86.437. [PMID: 11569618]
  • Z Zhang, J D Butler, S W Levin, K E Wisniewski, S S Brooks, A B Mukherjee. Lysosomal ceroid depletion by drugs: therapeutic implications for a hereditary neurodegenerative disease of childhood. Nature medicine. 2001 Apr; 7(4):478-84. doi: 10.1038/86554. [PMID: 11283676]
  • H Lee, I H Kim. Thioredoxin-linked lipid hydroperoxide peroxidase activity of human serum albumin in the presence of palmitoyl coenzyme A. Free radical biology & medicine. 2001 Feb; 30(3):327-33. doi: 10.1016/s0891-5849(00)00483-4. [PMID: 11165879]
  • K Murakami, T Ide, T Nakazawa, T Okazaki, T Mochizuki, T Kadowaki. Fatty-acyl-CoA thioesters inhibit recruitment of steroid receptor co-activator 1 to alpha and gamma isoforms of peroxisome-proliferator-activated receptors by competing with agonists. The Biochemical journal. 2001 Jan; 353(Pt 2):231-8. doi: 10.1042/0264-6021:3530231. [PMID: 11139385]
  • M L Chye, H Y Li, M H Yung. Single amino acid substitutions at the acyl-CoA-binding domain interrupt 14[C]palmitoyl-CoA binding of ACBP2, an Arabidopsis acyl-CoA-binding protein with ankyrin repeats. Plant molecular biology. 2000 Dec; 44(6):711-21. doi: 10.1023/a:1026524108095. [PMID: 11202434]
  • A L Thompson, G J Cooney. Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance. Diabetes. 2000 Nov; 49(11):1761-5. doi: 10.2337/diabetes.49.11.1761. [PMID: 11078441]
  • Y Takahashi, T Ide, H Fujita. Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2000 Oct; 127(2):213-22. doi: 10.1016/s0305-0491(00)00254-6. [PMID: 11079375]
  • V N Jackson, J M Cameron, F Fraser, V A Zammit, N T Price. Use of six chimeric proteins to investigate the role of intramolecular interactions in determining the kinetics of carnitine palmitoyltransferase I isoforms. The Journal of biological chemistry. 2000 Jun; 275(26):19560-6. doi: 10.1074/jbc.m002177200. [PMID: 10766754]
  • Y J Wan, Y Cai, C Cowan, T R Magee. Fatty acyl-CoAs inhibit retinoic acid-induced apoptosis in Hep3B cells. Cancer letters. 2000 Jun; 154(1):19-27. doi: 10.1016/s0304-3835(00)00341-4. [PMID: 10799735]
  • J T Dunphy, H Schroeder, R Leventis, W K Greentree, J K Knudsen, J R Silvius, M E Linder. Differential effects of acyl-CoA binding protein on enzymatic and non-enzymatic thioacylation of protein and peptide substrates. Biochimica et biophysica acta. 2000 May; 1485(2-3):185-98. doi: 10.1016/s1388-1981(00)00060-3. [PMID: 10832099]
  • J T Deeney, J Gromada, M Høy, H L Olsen, C J Rhodes, M Prentki, P O Berggren, B E Corkey. Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells). The Journal of biological chemistry. 2000 Mar; 275(13):9363-8. doi: 10.1074/jbc.275.13.9363. [PMID: 10734079]
  • S Sakuma, Y Fujimoto, Y Katoh, A Kitao, T Fujita. The regulation of prostaglandin and arachidonoyl-CoA formation from arachidonic acid in rabbit kidney medulla microsomes by palmitoyl-CoA. Life sciences. 2000 Feb; 66(12):1147-53. doi: 10.1016/s0024-3205(00)00418-5. [PMID: 10737365]
  • B Ruyter, M S Thomassen. Metabolism of n-3 and n-6 fatty acids in Atlantic salmon liver: stimulation by essential fatty acid deficiency. Lipids. 1999 Nov; 34(11):1167-76. doi: 10.1007/s11745-999-0468-3. [PMID: 10606039]
  • K A Nguyen, J M Carbone, V M Silva, C Chen, G E Hennig, H E Whiteley, J E Manautou. The PPAR activator docosahexaenoic acid prevents acetaminophen hepatotoxicity in male CD-1 mice. Journal of toxicology and environmental health. Part A. 1999 Oct; 58(3):171-86. doi: 10.1080/009841099157377. [PMID: 10522648]
  • L Ashakumary, I Rouyer, Y Takahashi, T Ide, N Fukuda, T Aoyama, T Hashimoto, M Mizugaki, M Sugano. Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat. Metabolism: clinical and experimental. 1999 Oct; 48(10):1303-13. doi: 10.1016/s0026-0495(99)90272-x. [PMID: 10535395]
  • Y J Day, Z Gao, P C Tan, J Linden. ATP sensitive potassium channel and myocardial preconditioning. Acta anaesthesiologica Sinica. 1999 Sep; 37(3):121-31. doi: . [PMID: 10609345]
  • R E McLaughlin, J B Denny. Palmitoylation of GAP-43 by the ER-Golgi intermediate compartment and Golgi apparatus. Biochimica et biophysica acta. 1999 Aug; 1451(1):82-92. doi: 10.1016/s0167-4889(99)00074-9. [PMID: 10446390]
  • K G Milne, M A Ferguson, P T Englund. A novel glycosylphosphatidylinositol in African trypanosomes. A possible catabolic intermediate. The Journal of biological chemistry. 1999 Jan; 274(3):1465-71. doi: 10.1074/jbc.274.3.1465. [PMID: 9880521]
  • S Iossa, L Lionetti, M P Mollica, A Barletta, G Liverini. Oxidative activity in mitochondria isolated from rat liver at different stages of development. Cell biochemistry and function. 1998 Dec; 16(4):261-8. doi: 10.1002/(sici)1099-0844(1998120)16:4<261::aid-cbf796>3.0.co;2-1. [PMID: 9857488]
  • M Orellana, R Rodrigo, E Valdés. Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption. General pharmacology. 1998 Nov; 31(5):817-20. doi: 10.1016/s0306-3623(98)00054-8. [PMID: 9809485]
  • I Schmidt, P Herpin. Carnitine palmitoyltransferase I (CPT I) activity and its regulation by malonyl-CoA are modulated by age and cold exposure in skeletal muscle mitochondria from newborn pigs. The Journal of nutrition. 1998 May; 128(5):886-93. doi: 10.1093/jn/128.5.886. [PMID: 9566999]
  • R A Coleman, P Wang, B G Bhat. Diradylglycerols alter fatty acid inhibition of monoacylglycerol acyltransferase activity in Triton X-100 mixed micelles. Biochemistry. 1998 Apr; 37(17):5916-22. doi: 10.1021/bi9802972. [PMID: 9558325]
  • P Sanchez, S U Tetzloff, O A Bizzozero. Veratridine-induced depolarization reduces the palmitoylation of brain and myelin glycerolipids. Journal of neurochemistry. 1998 Apr; 70(4):1448-57. doi: 10.1046/j.1471-4159.1998.70041448.x. [PMID: 9523561]
  • N Heise, F R Opperdoes. The dihydroxyacetonephosphate pathway for biosynthesis of ether lipids in Leishmania mexicana promastigotes. Molecular and biochemical parasitology. 1997 Oct; 89(1):61-72. doi: 10.1016/s0166-6851(97)00101-1. [PMID: 9297701]
  • J M Lenhard, S A Kliewer, M A Paulik, K D Plunket, J M Lehmann, J E Weiel. Effects of troglitazone and metformin on glucose and lipid metabolism: alterations of two distinct molecular pathways. Biochemical pharmacology. 1997 Oct; 54(7):801-8. doi: 10.1016/s0006-2952(97)00229-3. [PMID: 9353134]
  • L Missiaen, H De Smedt, J B Parys, H Sipma, K Maes, S Vanlingen, I Sienaert, W Van Driessche, R Casteels. Synergism between hypotonically induced calcium release and fatty acyl-CoA esters induced calcium release from intracellular stores. Cell calcium. 1997 Sep; 22(3):151-6. doi: 10.1016/s0143-4160(97)90008-7. [PMID: 9330785]
  • T L Jones, M Y Degtyarev, P S Backlund. The stoichiometry of G alpha(s) palmitoylation in its basal and activated states. Biochemistry. 1997 Jun; 36(23):7185-91. doi: 10.1021/bi9628376. [PMID: 9188719]
  • I I Tiurina, A Arduini, V A Tiurin, T V Sokolova, E Arrigoni-Martelli. [Palmitoylcarnitine-important component of lipid bilayer synaptosome membranes reparation system in oxidative stress]. Biulleten' eksperimental'noi biologii i meditsiny. 1997 Jun; 123(6):649-52. doi: ". [PMID: 9280517]
  • V Chigorno, E Negroni, M Nicolini, S Sonnino. Activity of 3-ketosphinganine synthase during differentiation and aging of neuronal cells in culture. Journal of lipid research. 1997 Jun; 38(6):1163-9. doi: . [PMID: 9215544]