melilotin (BioDeep_00000870416)

Main id: BioDeep_00000000442

 

PANOMIX_OTCML-2023


代谢物信息卡片


InChI=1\C9H8O2\c10-9-6-5-7-3-1-2-4-8(7)11-9\h1-4H,5-6H

化学式: C9H8O2 (148.0524)
中文名称: 二氢香豆素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(=O)OC2=CC=CC=C21
InChI: InChI=1S/C9H8O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-4H,5-6H2

描述信息

Dihydrocoumarin is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively[1].
Dihydrocoumarin is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively[1].
Dihydrocoumarin is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively[1].

同义名列表

60 个代谢物同义名

InChI=1\C9H8O2\c10-9-6-5-7-3-1-2-4-8(7)11-9\h1-4H,5-6H; Hydrocinnamic acid, o-hydroxy-, .delta.-lactone; Hydrocinnamic acid, o-hydroxy-, delta-lactone; 5-17-10-00013 (Beilstein Handbook Reference); o-hydroxyhydrocinnamic acid delta-lactone; Hydroxydihydrocinnamic acid lactone, o-; hydrocinnamic acid, o-hydroxy-,lactone; 2-Hydroxydihydrocinnamic acid lactone; o-hydroxydihydrocinnamic acid lactone; 2H-1-Benzopyran-2-one, 3, 4-dihydro-; o-hydroxyhydrocinnamic acid lactone; 2H-1-Benzopyran-2-one, 3,4-dihydro-; 3,4-Dihydro-2H-1-benzopyran-2-one; 3,4-Dihydro-1-benzopyran-2-one; 3,4-dihydro-2H-chromen-2-one; Benzopyranone, dihydro-; 1,2-benzodihydropyrone; Melilotic acid lactone; O-Hydroxycinnamic acid; Coumarin, 3,4-dihydro-; COUMARIN,3,4-DIHYDRO; 3,4-Dyhydrocoumarin; 3,4-Dihydrocoumarin; Benzodihydropyrone; Dihydrobenzopyrone; WLN: T66 BOVT & J; melilotic lactone; EINECS 204-354-9; NCGC00091491-01; Chroman, 2-oxo-; dihydrocoumarin; D104809_ALDRICH; W238104_ALDRICH; Chroman-2-one; hydrocoumarin; FEMA No. 2381; NCI60_000035; 2-chromanone; CHEBI:16151; BRN 0004584; AIDS-124064; Melilotine; NCI-C55890; Usaf do-12; AIDS124064; Oxochroman; CCRIS 5803; melilotin; Meliotine; NSC 10121; melilotol; 1341-36-2; ST5308259; AI3-03425; HSDB 4333; NSC10121; 119-84-6; C02274; c0397; Dihydrocoumarin



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ALB, ANXA5, CACNA1A, CAT, CYP2A6, HDAC9, RGN, SIRT1
Peripheral membrane protein 4 ANXA5, CYP1B1, PON2, SORD
Endoplasmic reticulum membrane 4 CYP1B1, CYP2A6, PON1, PON3
Mitochondrion membrane 1 SORD
Nucleus 7 ALB, CACNA1A, HDAC9, JUND, RAD52, RGN, SIRT1
cytosol 6 ALB, ANXA5, CAT, GPT, SIRT1, SORD
dendrite 1 MAOB
mitochondrial membrane 1 SORD
centrosome 1 ALB
nucleoplasm 4 HDAC9, JUND, RAD52, SIRT1
RNA polymerase II transcription regulator complex 1 JUND
Cell membrane 1 CACNA1A
Cytoplasmic side 1 MAOB
Multi-pass membrane protein 1 CACNA1A
Synapse 1 CACNA1A
Golgi apparatus 1 ALB
neuronal cell body 2 CACNA1A, MAOB
sarcolemma 1 ANXA5
plasma membrane 3 CACNA1A, IGHE, PON2
Membrane 7 ANXA5, CACNA1A, CAT, CYP1B1, CYP2A6, PON2, SORD
extracellular exosome 7 ALB, ANXA5, CAT, GPT, PON1, PON3, SORD
endoplasmic reticulum 1 ALB
extracellular space 7 ALB, CRP, IGHE, IL4, PON1, PON3, SORD
mitochondrion 4 CAT, CYP1B1, MAOB, SIRT1
protein-containing complex 3 ALB, CAT, RAD52
intracellular membrane-bounded organelle 3 CAT, CYP1B1, CYP2A6
Microsome membrane 1 CYP1B1
chromatin silencing complex 1 SIRT1
Single-pass type I membrane protein 1 IGHE
Secreted 3 ALB, CRP, IL4
extracellular region 9 ALB, ANXA5, CAT, CRP, IGHE, IL4, PON1, PON2, PON3
Mitochondrion outer membrane 1 MAOB
mitochondrial outer membrane 1 MAOB
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
transcription regulator complex 2 HDAC9, JUND
motile cilium 1 SORD
external side of plasma membrane 1 ANXA5
high-density lipoprotein particle 1 PON1
nucleolus 1 SIRT1
heterochromatin 1 SIRT1
focal adhesion 2 ANXA5, CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 SIRT1
PML body 1 SIRT1
collagen-containing extracellular matrix 1 ANXA5
nuclear inner membrane 1 SIRT1
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 ALB
chromatin 2 JUND, SIRT1
IgE immunoglobulin complex 1 IGHE
cell projection 1 CACNA1A
centriole 1 ALB
Secreted, extracellular space 1 PON3
spindle pole 1 ALB
blood microparticle 2 ALB, PON1
Cell projection, cilium, flagellum 1 SORD
[Isoform 2]: Cell membrane 1 IGHE
fibrillar center 1 SIRT1
nuclear envelope 1 SIRT1
monoatomic ion channel complex 1 CACNA1A
euchromatin 1 SIRT1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 ALB
histone methyltransferase complex 1 HDAC9
transcription repressor complex 1 JUND
platelet alpha granule lumen 1 ALB
voltage-gated calcium channel complex 1 CACNA1A
histone deacetylase complex 1 HDAC9
mitochondrial envelope 1 MAOB
Single-pass type IV membrane protein 1 MAOB
vesicle membrane 1 ANXA5
cytoplasmic microtubule 1 CYP2A6
protein-DNA complex 1 RAD52
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
[Isoform 3]: Cell membrane 1 IGHE
spherical high-density lipoprotein particle 1 PON1
transcription factor AP-1 complex 1 JUND
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
catalase complex 1 CAT
endothelial microparticle 1 ANXA5
ciliary transition fiber 1 ALB
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1


文献列表

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