2,3-cyclic AMP (BioDeep_00000412619)

Main id: BioDeep_00000003908

 

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


Adenosine 2,3-cyclic phosphate

化学式: C10H12N5O6P (329.0525182)
中文名称: 腺苷2,3-环状磷酸三乙铵盐, 腺苷 2':3'-循环磷酸钠盐 钠盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C4C(C(O3)CO)OP(=O)(O4)O)N
InChI: InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7-6(4(1-16)19-10)20-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)

描述信息

Adenosine 2,3-cyclic phosphate is part of the purine metabolism pathway. In this pathway, 2,3-cyclic AMP is reversibly converted to 3-AMP via the enzyme 2,3-cyclic-nucleotide 2-phosphodiesterase (EC 3.1.4.16). (KEGG) [HMDB]

同义名列表

2 个代谢物同义名

2,3-cyclic AMP; Adenosine 2,3-cyclic phosphate



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Edwin K Jackson, Zaichuan Mi, Keri Janesko-Feldman, Travis C Jackson, Patrick M Kochanek. 2',3'-cGMP exists in vivo and comprises a 2',3'-cGMP-guanosine pathway. American journal of physiology. Regulatory, integrative and comparative physiology. 2019 06; 316(6):R783-R790. doi: 10.1152/ajpregu.00401.2018. [PMID: 30789788]
  • Monika Kosmacz, Marcin Luzarowski, Olga Kerber, Ewa Leniak, Emilio Gutiérrez-Beltrán, Juan Camilo Moreno, Michał Gorka, Jagoda Szlachetko, Daniel Veyel, Alexander Graf, Aleksandra Skirycz. Interaction of 2',3'-cAMP with Rbp47b Plays a Role in Stress Granule Formation. Plant physiology. 2018 05; 177(1):411-421. doi: 10.1104/pp.18.00285. [PMID: 29618637]
  • Céline Mathieu-Demazière, Véréna Poinsot, Catherine Masson-Boivin, Anne-Marie Garnerone, Jacques Batut. Biochemical and functional characterization of SpdA, a 2', 3'cyclic nucleotide phosphodiesterase from Sinorhizobium meliloti. BMC microbiology. 2013 Nov; 13(?):268. doi: 10.1186/1471-2180-13-268. [PMID: 24279347]
  • Edwin K Jackson, Zaichuan Mi. In vivo cardiovascular pharmacology of 2',3'-cAMP, 2'-AMP, and 3'-AMP in the rat. The Journal of pharmacology and experimental therapeutics. 2013 Aug; 346(2):190-200. doi: 10.1124/jpet.113.205757. [PMID: 23759508]
  • Edwin K Jackson, Delbert G Gillespie. Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells. American journal of physiology. Renal physiology. 2013 Jan; 304(1):F49-55. doi: 10.1152/ajprenal.00571.2012. [PMID: 23077101]
  • Edwin K Jackson. The 2',3'-cAMP-adenosine pathway. American journal of physiology. Renal physiology. 2011 Dec; 301(6):F1160-7. doi: 10.1152/ajprenal.00450.2011. [PMID: 21937608]
  • Edwin K Jackson, Jin Ren, Dongmei Cheng, Zaichuan Mi. Extracellular cAMP-adenosine pathways in the mouse kidney. American journal of physiology. Renal physiology. 2011 Sep; 301(3):F565-73. doi: 10.1152/ajprenal.00094.2011. [PMID: 21653635]
  • Feng Rao, Yaning Qi, Elavazhagan Murugan, Swathi Pasunooti, Qiang Ji. 2',3'-cAMP hydrolysis by metal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screening. Biochemical and biophysical research communications. 2010 Jul; 398(3):500-5. doi: 10.1016/j.bbrc.2010.06.107. [PMID: 20599695]
  • Edwin K Jackson, Jin Ren, Zaichuan Mi. Extracellular 2',3'-cAMP is a source of adenosine. The Journal of biological chemistry. 2009 Nov; 284(48):33097-106. doi: 10.1074/jbc.m109.053876. [PMID: 19801686]
  • Jin Ren, Zaichuan Mi, Nicolas A Stewart, Edwin K Jackson. Identification and quantification of 2',3'-cAMP release by the kidney. The Journal of pharmacology and experimental therapeutics. 2009 Mar; 328(3):855-65. doi: 10.1124/jpet.108.146712. [PMID: 19033554]