3,7-Dimethyluric acid (BioDeep_00000405493)

natural product

3,7-Dimethyluric acid

分子结构信息

SMILES: CN1C(=O)NC2=C1C(=O)NC(=O)N2C
InChI: InChI=1S/C7H8N4O3/c1-10-3-4(8-6(10)13)11(2)7(14)9-5(3)12/h1-2H3,(H,8,13)(H,9,12,14)

An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trione substituted by methyl groups at N-3 and N-7.

2 个代谢物同义名

14 个数据库交叉引用编号

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表
Cytoplasm	2	CYP2E1, XDH
Peripheral membrane protein	1	CYP2E1
Endoplasmic reticulum membrane	3	CYP1A2, CYP2E1, TMX1
Mitochondrion membrane	1	TMX1
Nucleus	2	CBX4, ERH
cytosol	1	XDH
mitochondrial membrane	1	TMX1
nuclear body	1	CBX4
nucleoplasm	1	CBX4
Cell membrane	1	TNF
cell surface	1	TNF
Golgi membrane	1	INS
mitochondrial inner membrane	1	CYP2E1
neuronal cell body	1	TNF
plasma membrane	1	TNF
Membrane	1	TMX1
endoplasmic reticulum	1	TMX1
extracellular space	4	IL10, INS, TNF, XDH
intracellular membrane-bounded organelle	2	CYP1A2, CYP2E1
Microsome membrane	2	CYP1A2, CYP2E1
Single-pass type I membrane protein	1	TMX1
Secreted	3	IL10, INS, TMX1
extracellular region	4	IL10, INS, TMX1, TNF
external side of plasma membrane	1	TNF
midbody	1	ERH
recycling endosome	1	TNF
Single-pass type II membrane protein	1	TNF
Mitochondrion inner membrane	1	CYP2E1
Membrane raft	1	TNF
Peroxisome	1	XDH
sarcoplasmic reticulum	1	XDH
nuclear speck	1	CBX4
phagocytic cup	1	TNF
Endomembrane system	1	TMX1
endosome lumen	1	INS
mitochondria-associated endoplasmic reticulum membrane contact site	1	TMX1
Nucleus speckle	1	CBX4
secretory granule lumen	1	INS
Golgi lumen	1	INS
endoplasmic reticulum lumen	1	INS
PcG protein complex	1	CBX4
PRC1 complex	1	CBX4
transport vesicle	1	INS
Endoplasmic reticulum-Golgi intermediate compartment membrane	1	INS
methylosome	1	ERH
[Tumor necrosis factor, soluble form]: Secreted	1	TNF
[C-domain 2]: Secreted	1	TNF
[Tumor necrosis factor, membrane form]: Membrane	1	TNF
[C-domain 1]: Secreted	1	TNF

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S Gates, J O Miners. Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism. British journal of clinical pharmacology. 1999 Mar; 47(3):299-305. doi: 10.1046/j.1365-2125.1999.00890.x. [PMID: 10215755]
L Fraisse, J B Verlhac, B Roche, M C Rascle, A Rabion, J L Seris. Long-chain-substituted uric acid and 5,6-diaminouracil derivatives as novel agents against free radical processes: synthesis and in vitro activity. Journal of medicinal chemistry. 1993 May; 36(10):1465-73. doi: 10.1021/jm00062a020. [PMID: 8496914]