alpha-Methyl-m-tyrosine (BioDeep_00000008896)

 

Secondary id: BioDeep_00001876884

human metabolite blood metabolite


代谢物信息卡片


2-amino-3-(3-hydroxyphenyl)-2-methylpropanoic acid

化学式: C10H13NO3 (195.0895)
中文名称: DL-α-甲基间酪氨酸
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: CC(CC1=CC(=CC=C1)O)(C(=O)O)N
InChI: InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-3-2-4-8(12)5-7/h2-5,12H,6,11H2,1H3,(H,13,14)



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 2 DBH, TH
Nucleus 1 TH
cytosol 1 TH
dendrite 2 DRD2, TH
Cell membrane 1 DRD2
Cell projection, axon 1 TH
Multi-pass membrane protein 1 DRD2
Golgi apparatus membrane 1 DRD2
Synapse 2 DBH, DRD2
glutamatergic synapse 1 DRD2
Golgi membrane 1 DRD2
presynaptic membrane 1 DRD2
smooth endoplasmic reticulum 1 TH
synaptic vesicle 1 TH
acrosomal vesicle 1 DRD2
plasma membrane 1 DRD2
synaptic vesicle membrane 1 DRD2
terminal bouton 1 TH
Membrane 1 DBH
axon 2 DRD2, TH
endoplasmic reticulum 1 DBH
extracellular space 1 DBH
perinuclear region of cytoplasm 1 TH
mitochondrion 1 TH
intracellular membrane-bounded organelle 1 DBH
Secreted 1 DBH
extracellular region 1 DBH
cytoplasmic side of plasma membrane 1 TH
centriolar satellite 1 DBH
ciliary membrane 1 DRD2
dendritic spine 1 DRD2
perikaryon 2 DRD2, TH
cytoplasmic vesicle 1 TH
Melanosome membrane 1 TH
Single-pass type II membrane protein 1 DBH
postsynaptic membrane 1 DRD2
Cytoplasm, perinuclear region 1 TH
GABA-ergic synapse 1 DRD2
lateral plasma membrane 1 DRD2
neuron projection 1 TH
cilium 1 DRD2
non-motile cilium 1 DRD2
sperm flagellum 1 DRD2
secretory granule lumen 1 DBH
secretory granule membrane 1 DBH
axon terminus 1 DRD2
endocytic vesicle 1 DRD2
dopaminergic synapse 1 DRD2
Cytoplasmic vesicle, secretory vesicle membrane 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
transport vesicle membrane 1 DBH
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
G protein-coupled receptor complex 1 DRD2


文献列表

  • Manuel Rodriguez, Sergio Gonzalez, Ingrid Morales, Magdalena Sabate, Tomas Gonzalez-Hernandez, Jose Luis Gonzalez-Mora. Nigrostriatal cell firing action on the dopamine transporter. The European journal of neuroscience. 2007 May; 25(9):2755-65. doi: 10.1111/j.1460-9568.2007.05510.x. [PMID: 17561841]
  • J Sarkar, A Roy, T Chatterjee, A G Datta. Effect of some monoamine oxidase inhibitors and cyclic-AMP on plasma fibrinogen level of rats. Biochemical pharmacology. 1984 Feb; 33(4):539-42. doi: 10.1016/0006-2952(84)90304-6. [PMID: 6322807]
  • J Arita, J C Porter. Relationship between dopamine release into hypophysial portal blood and prolactin release after morphine treatment in rats. Neuroendocrinology. 1984 Jan; 38(1):62-7. doi: 10.1159/000123867. [PMID: 6320031]
  • N E ANDEN. THE URINARY EXCRETION AND THE TISSUE UPTAKE OF NORADRENALINE AFTER SEVERE TISSUE DEPLETION OF NORADRENALINE BY ALPHA-METHYL-META-TYROSINE AND METARAMINOL. Acta physiologica Scandinavica. 1965 May; 64(?):136-42. doi: 10.1111/j.1748-1716.1965.tb04161.x. [PMID: 14347271]