Chemical Formula: C10H13NO3
Chemical Formula C10H13NO3
Found 184 metabolite its formula value is C10H13NO3
Tyrosine methylester
Tyrosine methylester, also known as Tyrosine methyl ester hydrochloride, (L)-isomer or Tyr-ome, is classified as a tyrosine or a Tyrosine derivative. Tyrosines are compounds containing tyrosine or a derivative thereof resulting from reaction of tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. Tyrosine methylester is considered to be a slightly soluble (in water) and a very weak acidic compound. Tyrosine methylester can be found in humans. KEIO_ID T032 H-Tyr-OMe, an amino acid, is an endogenous metabolite[1].
Metyrosine
Metyrosine is only found in individuals that have used or taken this drug. It is an inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)Metyrosine inhibits tyrosine hydroxylase, which catalyzes the first transformation in catecholamine biosynthesis, i.e., the conversion of tyrosine to dihydroxyphenylalanine (DOPA). Because the first step is also the rate-limiting step, blockade of tyrosine hydroxylase activity results in decreased endogenous levels of catecholamines and their synthesis. This consequently, depletes the levels of the catecholamines dopamine, adrenaline and noradrenaline in the body,usually measured as decreased urinary excretion of catecholamines and their metabolites. One main end result of the catecholamine depletion is a decrease in blood presure. C - Cardiovascular system > C02 - Antihypertensives > C02K - Other antihypertensives > C02KB - Tyrosine hydroxylase inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C2155 - Tyrosine Hydroxylase Inhibitor D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
2-Phenyl-1,3-propanediol monocarbamate
2-Phenyl-1,3-propanediol monocarbamate is a metabolite of felbamate. Felbamate (marketed under the brand name Felbatol by MedPointe) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy. (Wikipedia)
L-Homotyrosine
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3-Methyl-l-tyrosine
A tyrosine derivative that is L-tyrosine in which the hydrogen at position 3 on the phenyl ring is replaced by a methyl group.
Surinamine
D010592 - Pharmaceutic Aids > D011310 - Preservatives, Pharmaceutical > D010226 - Parabens
N-Acetyldopamine
N-Acetyldopamine also known as NADA is an acetylated form of dopamine. It is an endogenously produced derivative or metabolite of dopamine. It belongs to the family of compounds known as catecholamines and derivatives. These are compounds containing 4-(2-aminoethyl) pyrocatechol [4-(2-aminoethyl) benzene-1,2-diol] or a derivative thereof. While NADA has been found in the human liver, kidney, and urine, it is unclear what its role is in mammal physiology (PMID: 16179545). NADA exists in both free and conjugated (glucuronide) forms. Conjugated NADA accounts for about 90\\\% of the total excretion of NADA. Urinary excretion of total N-acetyldopamine averages 0.485 micromoles/day in healthy humans (PMID: 6513727). The concentration of NADA is thirteen times higher in children with neuroblastoma than in normal subjects (PMID: 1321164). NADA is known to be a sepiapterin reductase inhibitor (PMID: 16179545). N-acetyldopamine has been shown to inhibit lipopolysaccharide-induced lipid peroxidation in rat brains (PMID: 16179545). N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle[1].
N-methyl-4,6,7-trihydroxy-1,2,3,4-tetrahydroisoquinoline
This compound belongs to the family of Isoquinolines and Derivatives. These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine
Racemetirosine
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
N-[2-(3,4-dimethoxyphenyl)ethylidene]hydroxylamine
N-A-BOC-N-D-Z-D-LYSINE
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
1-methyl-1,2,3,4-tetrahydroisoquinoline-4,6,7-triol
L-beta-Homotyrosine
Acquisition and generation of the data is financially supported in part by CREST/JST.
N-Acetyldopamine
A secondary carboxamide obtained by formal condensation of the carboxy group of acetic acid with the amino group of dopamine. A dopamine metabolite. N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle[1].
2-amino-3-(4-hydroxy-2-methylphenyl)propanoic acid
Methyl 4-amino-4,5,6,7-tetrahydrobenzofuran-3-carboxylate
(5-METHYL-PYRIDIN-2-YLOXY)-ACETIC ACID ETHYL ESTER
Ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate
3-AMINO-3-(2-HYDROXY-3-METHYL-PHENYL)-PROPIONIC ACID
3-(5-Formyl-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid
methyl 1-methyl-4-propionyl-1H-pyrrole-2-carboxylate
1H-Pyrrole-2-carboxylicacid, 4-formyl-3,5-dimethyl-, ethyl ester
3-Pyridinecarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-oxo-, ethyl ester
ETHYL 2,4-DIMETHYL-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXYLATE
2-AMINO-1-(2,3-DIHYDROBENZO[1,4]DIOXIN-6-YL)ETHANOL
3-AMINO-3-(4-HYDROXY-3-METHYL-PHENYL)-PROPIONIC ACID
1,2-Benzisoxazole-3-carboxylicacid, 4,5,6,7-tetrahydro-, ethyl ester
(4-METHYL-PYRIDIN-2-YLOXY)-ACETIC ACID ETHYL ESTER
Buramate
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
methyl 4-formyl-1,2,5-trimethylpyrrole-3-carboxylate
Benzoic acid, 5-amino-2-methoxy-, ethyl ester (9CI)
methyl 4-acetyl-2,5-dimethyl-1h-pyrrole-3-carboxylate
propan-2-yl 3-(hydroxymethyl)pyridine-2-carboxylate
1H-Isoindole-1,3(2H)-dione,3a,4,7,7a-tetrahydro-2-(2-hydroxyethyl)-
Racemetirosine
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
EU-0100093
N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle[1].
(2S)-2-ammonio-3-(4-hydroxy-3-methylphenyl)propanoate
Metyrosine
An L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. C - Cardiovascular system > C02 - Antihypertensives > C02K - Other antihypertensives > C02KB - Tyrosine hydroxylase inhibitors C471 - Enzyme Inhibitor > C2155 - Tyrosine Hydroxylase Inhibitor D004791 - Enzyme Inhibitors
3-methyl-L-tyrosine zwitterion
An amino acid zwitterion resulting from a transfer of a proton from the carboxy to the amino group of 3-methyl-L-tyrosine; major species at pH 7.3.
N-acetyloctopamine
A member of the class of tyramines that is octopamine in which one of the amino hydrogens is replaced by an acetyl group. It is a metabolite of octopamine which is found in the brains of ants and fruit flies.