Diazene (BioDeep_00000005799)

 

Secondary id: BioDeep_00001868955

human metabolite blood metabolite


代谢物信息卡片


Diimide

化学式: H2N2 (30.0218)
中文名称:
谱图信息: 最多检出来源 not specific(not specific) 0%

分子结构信息

SMILES: N=N
InChI: InChI=1S/H2N2/c1-2/h1-2H

描述信息

同义名列表

4 个代谢物同义名

Diimide; diimine; Diazene; HN=nh



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

  • isoniazid activation: NAD+ + NADH + isonicotinate acyl radical ⟶ H+ + isonicotinate acyl-NADH adduct
  • isoniazid activation: NAD+ + NADH + isonicotinate acyl radical ⟶ H+ + isonicotinate acyl-NADH adduct

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ANXA5, AXIN2, BCL2, CASP3, CAT, DROSHA, GRHPR, MSMP, PMP2, RIPK4
Peripheral membrane protein 4 ANXA5, CYP1B1, PRTN3, RIPK4
Endoplasmic reticulum membrane 2 BCL2, CYP1B1
Nucleus 6 AXIN2, BCL2, CASP3, CUL2, DROSHA, PMP2
cytosol 11 ANXA5, AXIN2, BCL2, CASP3, CAT, CUL2, DROSHA, GRHPR, MB, PMP2, PRTN3
centrosome 1 AXIN2
nucleoplasm 3 CASP3, CUL2, DROSHA
Cell membrane 2 KIR3DL1, PRTN3
Cytoplasmic granule 1 PRTN3
Multi-pass membrane protein 1 SLC9C1
cell surface 1 C3
glutamatergic synapse 2 CASP3, DROSHA
neuronal cell body 1 CASP3
sarcolemma 1 ANXA5
plasma membrane 7 AXIN2, C3, KIR3DL1, ME2, ME3, PRTN3, SLC9C1
Membrane 9 ANXA5, BCL2, CAT, CYP1B1, KIR3DL1, ME2, ME3, RIPK4, SLC9C1
extracellular exosome 7 ANXA5, C3, CAT, GRHPR, MB, PMP2, PRTN3
endoplasmic reticulum 1 BCL2
extracellular space 3 C3, MSMP, PRTN3
mitochondrion 6 BCL2, CAT, CYP1B1, GRHPR, ME2, ME3
protein-containing complex 3 BCL2, C3, CAT
intracellular membrane-bounded organelle 4 CAT, CYP1B1, ME2, PRTN3
Microsome membrane 1 CYP1B1
postsynaptic density 2 CASP3, DROSHA
Single-pass type I membrane protein 1 KIR3DL1
Secreted 3 C3, MSMP, PRTN3
extracellular region 4 ANXA5, C3, CAT, PRTN3
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 3 BCL2, ME2, ME3
mitochondrial outer membrane 1 BCL2
Mitochondrion matrix 1 ME2
mitochondrial matrix 3 CAT, ME2, ME3
Extracellular side 1 PRTN3
motile cilium 1 SLC9C1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 ANXA5
beta-catenin destruction complex 1 AXIN2
nucleolus 2 CUL2, DROSHA
sarcoplasm 1 MB
Membrane raft 1 PRTN3
pore complex 1 BCL2
focal adhesion 2 ANXA5, CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, GRHPR
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 ANXA5
Zymogen granule membrane 1 ANXA5
Nucleus, nucleolus 1 DROSHA
blood microparticle 1 C3
Cul2-RING ubiquitin ligase complex 1 CUL2
Cell projection, cilium, flagellum membrane 1 SLC9C1
myelin sheath 2 BCL2, PMP2
plasma membrane raft 1 PRTN3
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 C3, CAT
endoplasmic reticulum lumen 1 C3
azurophil granule lumen 2 C3, PRTN3
vesicle membrane 1 ANXA5
death-inducing signaling complex 1 CASP3
Cytoplasm, sarcoplasm 1 MB
catalase complex 1 CAT
catalytic complex 1 GRHPR
endothelial microparticle 1 ANXA5
SCF ubiquitin ligase complex 1 CUL2
BAD-BCL-2 complex 1 BCL2
cullin-RING ubiquitin ligase complex 1 CUL2
VCB complex 1 CUL2
microprocessor complex 1 DROSHA


文献列表

  • Khaled R A Abdellatif, Ying Dong, Qiao-Hong Chen, Morshed Alam Chowdhury, Edward E Knaus. Novel (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic ester prodrugs possessing a diazen-1-ium-1,2-diolate moiety: design, synthesis, cyclooxygenase inhibition, and nitric oxide release studies. Bioorganic & medicinal chemistry. 2007 Nov; 15(21):6796-801. doi: 10.1016/j.bmc.2007.07.021. [PMID: 17764958]
  • D L Garver, D M Davis, H Dekirmenjian, S Ericksen, L Gosenfeld, J Haraszti. Dystonic reactions following neuroleptics: time course and proposed mechanisms. Psychopharmacologia. 1976 May; 47(2):199-201. doi: 10.1007/bf00735822. [PMID: 5743]