lipid IVA (BioDeep_00000005700)

 

Secondary id: BioDeep_00000180496

natural product


代谢物信息卡片


[(3S,5S,6R)-3-hydroxy-2-[[(2R,3S,5S)-6-(hydroxymethyl)-3-[[(3R)-3-hydroxytetradecanoyl]amino]-4-[(3R)-3-hydroxytetradecanoyl]oxy-5-phosphonooxyoxan-2-yl]oxymethyl]-5-[[(3R)-3-hydroxytetradecanoyl]amino]-6-phosphonooxyoxan-4-yl] (3R)-3-hydroxytetradecanoate

化学式: C68H130N2O23P2 (1404.8539)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 92.68%

分子结构信息

SMILES: CCCCCCCCCCCC(CC(=O)NC1C(C(C(OC1OP(=O)(O)O)COC2C(C(C(C(O2)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)O)NC(=O)CC(CCCCCCCCCCC)O)O)OC(=O)CC(CCCCCCCCCCC)O)O
InChI: InChI=1S/C68H130N2O23P2/c1-5-9-13-17-21-25-29-33-37-41-51(72)45-57(76)69-61-65(90-59(78)47-53(74)43-39-35-31-27-23-19-15-11-7-3)63(80)56(89-68(61)93-95(84,85)86)50-87-67-62(70-58(77)46-52(73)42-38-34-30-26-22-18-14-10-6-2)66(64(55(49-71)88-67)92-94(81,82)83)91-60(79)48-54(75)44-40-36-32-28-24-20-16-12-8-4/h51-56,61-68,71-75,80H,5-50H2,1-4H3,(H,69,76)(H,70,77)(H2,81,82,83)(H2,84,85,86)/t51-,52-,53-,54-,55-,56-,61-,62-,63-,64-,65-,66-,67-,68-/m1/s1

描述信息

同义名列表

6 个代谢物同义名

lipid IVA; [(3S,5S,6R)-3-hydroxy-2-[[(2R,3S,5S)-6-(hydroxymethyl)-3-[[(3R)-3-hydroxytetradecanoyl]amino]-4-[(3R)-3-hydroxytetradecanoyl]oxy-5-phosphonooxyoxan-2-yl]oxymethyl]-5-[[(3R)-3-hydroxytetradecanoyl]amino]-6-phosphonooxyoxan-4-yl] (3R)-3-hydroxytetradecanoate; 2,3,23-Tetrakis(β-hydroxymyristoyl)-D-glucosaminyl-1,6-β-D- glucosamine 1,4-bisphosphate; 2,3,23-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-β-D- glucosamine 1,4-bisphosphate; Lipid A disaccharide bisphosphate; Lipid IV(A)



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

85 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(84)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 CCL5, HMGB1, IRF3, MYD88, NFKBIA, TLR2, TLR4, TRIM69
Peripheral membrane protein 1 HMGB1
Endosome membrane 4 CD14, LY96, MYD88, TLR4
Nucleus 5 HMGB1, IRF3, MYD88, NFKBIA, TRIM69
cytosol 5 IL1B, IRF3, MYD88, NFKBIA, TRIM69
centrosome 1 TRIM69
nucleoplasm 4 CD180, HMGB1, IRF3, NFKBIA
Cell membrane 7 CD14, HMGB1, ITGAM, ITGB2, TLR1, TLR4, TNF
cell surface 7 HMGB1, ITGAM, ITGB2, MYD88, TLR2, TLR4, TNF
Golgi apparatus 4 ATRN, CD14, TLR1, TLR2
neuronal cell body 1 TNF
Cytoplasm, cytosol 1 IL1B
Lysosome 1 IL1B
endosome 1 HMGB1
plasma membrane 13 ATRN, CD14, CD180, HMGB1, ITGAM, ITGB2, LY96, MYD88, NFKBIA, TLR1, TLR2, TLR4, TNF
Membrane 5 ITGAM, ITGB2, TLR1, TLR2, TLR4
extracellular exosome 4 ATRN, CD14, ITGAM, ITGB2
endoplasmic reticulum 1 HMGB1
extracellular space 9 ATRN, CCL5, CD14, CD180, HMGB1, IL1B, IL6, ITGAM, TNF
perinuclear region of cytoplasm 1 TLR4
mitochondrion 1 IRF3
protein-containing complex 1 MYD88
Single-pass type I membrane protein 6 ATRN, ITGAM, ITGB2, TLR1, TLR2, TLR4
Secreted 7 AOAH, CCL5, CD14, HMGB1, IL1B, IL6, LY96
extracellular region 9 AOAH, CCL5, CD14, HMGB1, IL1B, IL6, LY86, LY96, TNF
[Isoform 2]: Secreted 1 ATRN
Extracellular side 1 HMGB1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TRIM69
external side of plasma membrane 5 CD14, ITGAM, ITGB2, TLR4, TNF
Extracellular vesicle 1 ITGB2
cytoplasmic vesicle 1 AOAH
nucleolus 1 CD180
Early endosome 1 TLR4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 6 CD14, ITGAM, ITGB2, TLR1, TLR2, TNF
focal adhesion 1 ITGB2
extracellular matrix 1 CD180
secretory granule 1 IL1B
nuclear speck 1 TRIM69
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 5 ITGB2, LY96, TLR1, TLR2, TLR4
chromatin 1 IRF3
Cytoplasmic vesicle, phagosome membrane 2 TLR1, TLR2
cell projection 1 TLR2
phagocytic cup 2 TLR4, TNF
phagocytic vesicle membrane 2 TLR1, TLR2
mitotic spindle 1 CD180
Chromosome 1 HMGB1
Secreted, extracellular space 1 LY96
Lipid-anchor, GPI-anchor 1 CD14
[Isoform 3]: Secreted 1 ATRN
specific granule membrane 2 ITGAM, ITGB2
tertiary granule membrane 2 ITGAM, ITGB2
Nucleus speckle 1 TRIM69
cell body 1 TLR2
side of membrane 1 CD14
lipopolysaccharide receptor complex 3 CD14, LY96, TLR4
plasma membrane raft 2 ITGAM, ITGB2
ficolin-1-rich granule lumen 1 HMGB1
secretory granule lumen 1 HMGB1
secretory granule membrane 2 CD14, TLR2
endoplasmic reticulum lumen 1 IL6
transcription repressor complex 1 HMGB1
Secreted, extracellular exosome 1 IL1B
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
extrinsic component of cytoplasmic side of plasma membrane 1 MYD88
ficolin-1-rich granule membrane 1 ITGB2
[Isoform 1]: Cell membrane 1 ATRN
condensed chromosome 1 HMGB1
Toll-like receptor 1-Toll-like receptor 2 protein complex 2 TLR1, TLR2
Toll-like receptor 2-Toll-like receptor 6 protein complex 1 TLR2
extrinsic component of plasma membrane 1 MYD88
integrin complex 2 ITGAM, ITGB2
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
integrin alphaL-beta2 complex 1 ITGB2
integrin alphaM-beta2 complex 2 ITGAM, ITGB2
integrin alphaX-beta2 complex 1 ITGB2
interleukin-6 receptor complex 1 IL6
I-kappaB/NF-kappaB complex 1 NFKBIA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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