Acrolein (BioDeep_00000004696)

 

Secondary id: BioDeep_00000864481, BioDeep_00001867609

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Toxin


代谢物信息卡片


trans-Acrolein formylethylene

化学式: C3H4O (56.0262)
中文名称: 丙烯醛, 丙烯醛 107-02-8 标准品
谱图信息: 最多检出来源 Homo sapiens(plant) 12.75%

分子结构信息

SMILES: C=CC=O
InChI: InChI=1S/C3H4O/c1-2-3-4/h2-3H,1H2

描述信息

Acrolein (systematic name: propenal) is the simplest unsaturated aldehyde. It is a colourless liquid with a piercing, disagreeable, acrid smell. The smell of burnt fat (i.e. when cooking oil is heated to its smoke point) is caused by glycerol in the burning fat breaking down into acrolein. It is produced industrially from propylene and mainly used as a biocide and a building block to other chemical compounds, such as the amino acid methionine. Acrolein is used as an etherification agent in the preparation of modified food starches. Acrolein is an herbicide and algicide used in water treatment. It is produced by microorganisms, e.g. Clostridium perfringens. Acrolein is a relatively electrophilic compound and a reactive one, hence its high toxicity. It is a good Michael acceptor, hence its useful reaction with thiols. It forms acetals readily, a prominent one being the spirocycle derived from pentaerythritol, diallylidene pentaerythritol. Acrolein participates in many Diels-Alder reactions, even with itself. Via Diels-Alder reactions, it is a precursor to some commercial fragrances, including lyral, norbornene-2-carboxaldehyde, and myrac aldehyde. Acrolein is toxic and is a strong irritant for the skin, eyes, and nasal passages. The main metabolic pathway for acrolein is the alkylation of glutathione. The WHO suggests a tolerable oral acrolein intake of 7.5 µg/day per kilogram of body weight. Although acrolein occurs in French fries, the levels are only a few micrograms per kilogram. Acrolein has also been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID:22626821).
Present in fruit aromas, black tea, carrot, cooked potato, cheeses, white wine, hydrolyzed soy protein, turkey, pork, beef fat and other foods. It is used as an etherification agent in the preparation of modified food starches. Herbicide and algicide used in water treatment. Production by microorganisms, e.g. Clostridium perfringens. 2-Propenal is found in many foods, some of which are napa cabbage, sacred lotus, devilfish, and garlic.

同义名列表

33 个代谢物同义名

trans-Acrolein formylethylene; Propylene aldehyde; Aldehyde, ethylene; Ethylene aldehyde; Aldehyde, acrylic; Magnacide H and b; Acrylic aldehyde; 2-Propenaldehyde; Aldehyde, allyl; Allyl aldehyde; Prop-2-en-1-al; Propenaldehyde; 2-Propen-1-one; Acrylaldehyde; Magnacide H; Acraldehyde; Prop-2-enal; 2 Propenal; 2-Propenal; Acroleina; Acquinite; Slimicide; CH2=chcho; Magnacide; ACROLEIN; Aqualine; Propenal; Aqualin; Biocide; Crolean; Papite; Acrolein; Acrolein



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

125 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(119)

COVID-19 Disease Map(0)

PathBank(4)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKR1B1, ALB, AOC3, CASP1, CAT, ELANE, GAPDH, HPGDS, NOS3, NQO1, SMOX
Nucleus 7 ACR, ALB, GAPDH, MPO, NOS3, NQO1, SMOX
cytosol 11 AKR1B1, ALB, CASP1, CAT, ELANE, GAPDH, HPGDS, NOS3, NQO1, PRKCQ, SMOX
dendrite 1 NQO1
phagocytic vesicle 1 ELANE
centrosome 1 ALB
nucleoplasm 5 AKR1B1, HPGDS, MPO, NOS3, SMOX
Cell membrane 4 AOC3, CASP1, TNF, TRPA1
Multi-pass membrane protein 1 TRPA1
Synapse 2 NQO1, TAC1
cell surface 3 AOC3, ELANE, TNF
Golgi apparatus 3 ALB, AOC3, NOS3
Golgi membrane 2 INS, NOS3
neuronal cell body 3 NQO1, TAC1, TNF
Cytoplasm, cytosol 2 GAPDH, NQO1
Lysosome 1 MPO
plasma membrane 7 AOC3, CASP1, GAPDH, NOS3, PRKCQ, TNF, TRPA1
Membrane 5 AOC3, CAT, GAPDH, NQO1, TRPA1
axon 1 TAC1
caveola 1 NOS3
extracellular exosome 6 AKR1B1, ALB, CAT, ELANE, GAPDH, MPO
endoplasmic reticulum 2 ALB, AOC3
extracellular space 9 AKR1B1, ALB, CRP, ELANE, IL6, INS, MPO, TAC1, TNF
perinuclear region of cytoplasm 2 GAPDH, NOS3
mitochondrion 2 AKR1B1, CAT
protein-containing complex 4 ACR, ALB, CASP1, CAT
intracellular membrane-bounded organelle 5 CAT, GAPDH, HPGDS, MPO, SMOX
Secreted 4 ALB, CRP, IL6, INS
extracellular region 10 ACR, ALB, CAT, CRP, ELANE, IL6, INS, MPO, TAC1, TNF
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
nuclear membrane 2 GAPDH, SMOX
external side of plasma membrane 1 TNF
microtubule cytoskeleton 1 GAPDH
nucleolus 1 CASP1
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
Early endosome 1 AOC3
Golgi-associated vesicle 1 ACR
recycling endosome 1 TNF
Single-pass type II membrane protein 2 AOC3, TNF
vesicle 1 GAPDH
Cytoplasm, perinuclear region 1 GAPDH
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 1 CAT
microtubule 1 CASP1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 ELANE
secretory granule 2 ELANE, MPO
NLRP3 inflammasome complex 1 CASP1
ciliary basal body 1 ALB
stereocilium bundle 1 TRPA1
phagocytic cup 1 TNF
cytoskeleton 2 GAPDH, NOS3
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
endosome lumen 1 INS
microvillus 1 AOC3
Lipid droplet 1 GAPDH
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, IL6, INS
transcription repressor complex 1 ELANE
platelet alpha granule lumen 1 ALB
specific granule lumen 1 ELANE
endocytic vesicle membrane 1 NOS3
transport vesicle 1 INS
azurophil granule lumen 2 ELANE, MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
AIM2 inflammasome complex 1 CASP1
phagocytic vesicle lumen 1 MPO
ribonucleoprotein complex 1 GAPDH
canonical inflammasome complex 1 CASP1
Cytoplasmic vesicle, phagosome 1 ELANE
GAIT complex 1 GAPDH
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
acrosomal matrix 1 ACR
IPAF inflammasome complex 1 CASP1
NLRP1 inflammasome complex 1 CASP1
protease inhibitor complex 1 CASP1
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Chen-Yan Li, Li-Juan Liao, Shi-Xian Yang, Lu-Yao Wang, Hao Chen, Peipei Luo, Gan-Rong Huang, Yan-Qiang Huang. Cinnamaldehyde: An effective component of Cinnamomum cassia inhibiting Helicobacter pylori. Journal of ethnopharmacology. 2024 Aug; 330(?):118222. doi: 10.1016/j.jep.2024.118222. [PMID: 38663778]
  • Fugang Liu, Yanfang Yang, Haoran Dong, Yanhui Zhu, Weisheng Feng, Hezhen Wu. Essential oil from Cinnamomum cassia Presl bark regulates macrophage polarization and ameliorates lipopolysaccharide-induced acute lung injury through TLR4/MyD88/NF-κB pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155651. doi: 10.1016/j.phymed.2024.155651. [PMID: 38688144]
  • Narges Hojati, Sedigheh Amiri, Elahe Abedi, Mohsen Radi. Effect of cinnamaldehyde-nanoemulsion and nanostructured lipid carriers on physicochemical attributes of reduced-nitrite sausages. Food chemistry. 2024 Jun; 444(?):138658. doi: 10.1016/j.foodchem.2024.138658. [PMID: 38325076]
  • Jinyue Sun, Qian-Jun Shen, Jia-Neng Pan, Xiaodong Zheng, Ting Yu, Wen-Wen Zhou. Ferrous sulfate combined with ultrasound emulsified cinnamaldehyde nanoemulsion to cause ferroptosis in Escherichia coli O157:H7. Ultrasonics sonochemistry. 2024 Jun; 106(?):106884. doi: 10.1016/j.ultsonch.2024.106884. [PMID: 38677267]
  • Abeer S Elsherbiny, Alyaa Galal, Khalid M Ghoneem, Nehal A Salahuddin. Graphene oxide-based nanocomposites for outstanding eco-friendly antifungal potential against tomato phytopathogens. Biomaterials advances. 2024 Jun; 160(?):213863. doi: 10.1016/j.bioadv.2024.213863. [PMID: 38642516]
  • Nesma A Ghazal, Yara T Agamia, Basant K Meky, Nagwa M Assem, Wafaa M Abdel-Rehim, Sara A Shaker. Cinnamaldehyde ameliorates STZ-induced diabetes through modulation of autophagic process in adipocyte and hepatic tissues on rats. Scientific reports. 2024 05; 14(1):10053. doi: 10.1038/s41598-024-60150-2. [PMID: 38698047]
  • Peng Ye, Jianmu Su, Jianhao Lin, Yanqun Li, Hong Wu. Identification of a cinnamoyl-CoA reductase from Cinnamomum cassia involved in trans-cinnamaldehyde biosynthesis. Planta. 2024 Apr; 259(6):138. doi: 10.1007/s00425-024-04419-w. [PMID: 38687380]
  • Antonella L Grosso, Ksenia Morozova, Giovanna Ferrentino, Franco Biasioli, Matteo Scampicchio. Early detection of acrolein precursors in vegetable oils by using proton transfer reaction - mass spectrometry. Talanta. 2024 Apr; 270(?):125513. doi: 10.1016/j.talanta.2023.125513. [PMID: 38128278]
  • Yan-Guang Li, Jiang-Hong Li, Hai-Qin Wang, Junhua Liao, Xiao-Ya Du. Cinnamaldehyde protects cardiomyocytes from oxygen-glucose deprivation/reoxygenation-induced lipid peroxidation and DNA damage via activating the Nrf2 pathway. Chemical biology & drug design. 2024 02; 103(2):e14489. doi: 10.1111/cbdd.14489. [PMID: 38404216]
  • Yun Meng, Ye Cai, Mengyao Cui, Yuhang Xu, Long Wu, Xiang Li, Xiaoqin Chu. Solid self-microemulsifying drug delivery system (S-SMEDDS) prepared by spray drying to improve the oral bioavailability of cinnamaldehyde (CA). Pharmaceutical development and technology. 2024 Feb; 29(2):112-122. doi: 10.1080/10837450.2024.2312851. [PMID: 38308442]
  • Aleksandra Zimińska, Izabela Lipska, Joanna Gajewska, Anna Draszanowska, Manuel Simões, Magdalena A Olszewska. Antibacterial and Antibiofilm Effects of Photodynamic Treatment with Curcuma L. and Trans-Cinnamaldehyde against Listeria monocytogenes. Molecules (Basel, Switzerland). 2024 Feb; 29(3):. doi: 10.3390/molecules29030685. [PMID: 38338429]
  • Mustafa Cemre Sonmez, Side Selin Su Yirmibesoglu, Rengin Ozgur, Baris Uzilday, Ismail Turkan. Roles of Reactive Carbonyl Species (RCS) in Plant Response to Abiotic Stress. Methods in molecular biology (Clifton, N.J.). 2024; 2798(?):101-130. doi: 10.1007/978-1-0716-3826-2_7. [PMID: 38587738]
  • Jishuai Sun, Xiaojing Leng, Jiachen Zang, Guanghua Zhao. Bio-based antibacterial food packaging films and coatings containing cinnamaldehyde: A review. Critical reviews in food science and nutrition. 2024; 64(1):140-152. doi: 10.1080/10408398.2022.2105300. [PMID: 35900224]
  • Edouard Pesquet, Leonard Blaschek, Junko Takahashi, Masanobu Yamamoto, Antoine Champagne, Nuoendagula, Elena Subbotina, Charilaos Dimotakis, Zoltan Bascik, Shinya Kajita. Bulk and In Situ Quantification of Coniferaldehyde Residues in Lignin. Methods in molecular biology (Clifton, N.J.). 2024; 2722(?):201-226. doi: 10.1007/978-1-0716-3477-6_14. [PMID: 37897609]
  • Jihye Jung, Dawon Jo, Soo-Jin Kim. Transcriptional Response of Pectobacterium carotovorum to Cinnamaldehyde Treatment. Journal of microbiology and biotechnology. 2023 Dec; 34(4):1-9. doi: 10.4014/jmb.2311.11043. [PMID: 38146216]
  • Huihui Gu, Bo Si, Chen Yang, Mengwei Jia, Yongling Lu, Lishuang Lv, Yuxing Guo. Elimination of Acrolein by Disodium 5'-Guanylate or Disodium 5'-Inosinate at High Temperature and Its Application in Roasted Pork Patty. Journal of agricultural and food chemistry. 2023 Dec; 71(50):20314-20324. doi: 10.1021/acs.jafc.3c05064. [PMID: 38078910]
  • Imam Tri Wahyudi, Dedi Jusadi, Mia Setiawati, Julie Ekasari, Muhammad Agus Suprayudi. Dietary supplementation of cinnamaldehyde positively affects the physiology, feed utilization, growth, and body composition of striped catfish Pangasianodon hypophthalmus. Fish physiology and biochemistry. 2023 Dec; ?(?):. doi: 10.1007/s10695-023-01287-1. [PMID: 38112905]
  • Joshua M Lyte, Komala Arsi, Valentina Caputi, Rohana Liyanage, Anna L Facchetti V Assumpcao, Palmy R R Jesudhasan, Annie M Donoghue. Inclusion of trans-cinnamaldehyde and caprylic acid in feed results in detectable concentrations in the chicken gut and reduces foodborne pathogen carriage. Poultry science. 2023 Dec; 103(2):103368. doi: 10.1016/j.psj.2023.103368. [PMID: 38157787]
  • Devin I Alewel, Katherine M Rentschler, Thomas W Jackson, Mette C Schladweiler, Anna Astriab-Fisher, Paul A Evansky, Urmila P Kodavanti. Serum metabolome and liver transcriptome reveal acrolein inhalation-induced sex-specific homeostatic dysfunction. Scientific reports. 2023 12; 13(1):21179. doi: 10.1038/s41598-023-48413-w. [PMID: 38040807]
  • Bing Qian, Yonghua Hu, Minggao Xu, Jiuzhong Yang, Chengyuan Liu, Yang Pan. Study on the thermal oxidation of oleic, linoleic and linolenic acids by synchrotron radiation photoionization mass spectrometry. Rapid communications in mass spectrometry : RCM. 2023 Nov; 37(21):e9634. doi: 10.1002/rcm.9634. [PMID: 37799030]
  • Chen Yan, Na Li, Yuchi Zhang, Yun Wei. Enrichment of cinnamaldehyde from Cinnamomum cassia by electroosmotic coupled particle-assisted solvent flotation. Journal of chromatography. A. 2023 Nov; 1710(?):464411. doi: 10.1016/j.chroma.2023.464411. [PMID: 37778100]
  • Chunbo Kang, Jie Zhang, Mei Xue, Xiaowei Li, Danyang Ding, Ye Wang, Shujing Jiang, Fong-Fong Chu, Qiang Gao, Mengqiao Zhang. Metabolomics analyses of cancer tissue from patients with colorectal cancer. Molecular medicine reports. 2023 Nov; 28(5):. doi: 10.3892/mmr.2023.13106. [PMID: 37772396]
  • Koichi Yoshioka, Hoon Kim, Fachuang Lu, Nette De Ridder, Ruben Vanholme, Shinya Kajita, Wout Boerjan, John Ralph. Hydroxycinnamaldehyde-derived benzofuran components in lignins. Plant physiology. 2023 Sep; ?(?):. doi: 10.1093/plphys/kiad514. [PMID: 37773018]
  • Sanne van Gastelen, David Yáñez-Ruiz, Hajer Khelil-Arfa, Alexandra Blanchard, André Bannink. Effect of a blend of cinnamaldehyde, eugenol, and capsicum oleoresin on methane emission and lactation performance of Holstein-Friesian dairy cows. Journal of dairy science. 2023 Sep; ?(?):. doi: 10.3168/jds.2023-23406. [PMID: 37709037]
  • Hend Dawood, Ismail Celik, Reham S Ibrahim. Computational biology and in vitro studies for anticipating cancer-related molecular targets of sweet wormwood (Artemisia annua). BMC complementary medicine and therapies. 2023 Sep; 23(1):312. doi: 10.1186/s12906-023-04135-0. [PMID: 37684586]
  • Faizan Abul Qais, Mohammad Shavez Khan, Iqbal Ahmad, Fohad Mabood Husain, Mohammed Arshad, Altaf Khan, Mohd Adil. Modulation of quorum sensing and biofilm of Gram-negative bacterial pathogens by Cinnamomum zeylanicum L. Microscopy research and technique. 2023 Sep; ?(?):. doi: 10.1002/jemt.24410. [PMID: 37660303]
  • Suneel Gupta, Lynn M Martin, Eric Zhang, Prashant R Sinha, James Landreneau, Nishant R Sinha, Nathan P Hesemann, Rajiv R Mohan. Toxicological effects of ocular acrolein exposure to eyelids in rabbits in vivo. Experimental eye research. 2023 09; 234(?):109575. doi: 10.1016/j.exer.2023.109575. [PMID: 37451567]
  • Mohaddeseh Khaafi, Zahra Tayarani-Najaran, Behjat Javadi. Cinnamaldehyde as a promising dietary phytochemical against metabolic syndrome: A systematic review. Mini reviews in medicinal chemistry. 2023 Jul; ?(?):. doi: 10.2174/1389557523666230725113446. [PMID: 37489782]
  • Hong-Chieh Tsai, Zhen-Jie Tong, Tsong-Long Hwang, Kuo-Chen Wei, Pin-Yuan Chen, Chiung-Yin Huang, Ko-Ting Chen, Ya-Jui Lin, Hsiao-Wei Cheng, Hsiang-Tsui Wang. Acrolein produced by glioma cells under hypoxia inhibits neutrophil AKT activity and suppresses anti-tumoral activities. Free radical biology & medicine. 2023 Jul; ?(?):. doi: 10.1016/j.freeradbiomed.2023.06.027. [PMID: 37414347]
  • Jiang Chen, Hua Wang, Yuanshan Chen, Qiujin Zhu, Jing Wan. Inhibitive effect and mechanism of cinnamaldehyde on growth and OTA production of Aspergillus niger in vitro and in dried red chilies. Food research international (Ottawa, Ont.). 2023 06; 168(?):112794. doi: 10.1016/j.foodres.2023.112794. [PMID: 37120239]
  • Bin Wang, Wei Liu, Linling Yu, Zi Ye, Man Cheng, Weihong Qiu, Min Zhou, Jixuan Ma, Xing Wang, Meng Yang, Jiahao Song, Weihong Chen. Acrolein Exposure Impaired Glucose Homeostasis and Increased Risk of Type 2 Diabetes: An Urban Adult Population-Based Cohort Study with Repeated Measures. Environmental science & technology. 2023 May; 57(18):7162-7173. doi: 10.1021/acs.est.2c09299. [PMID: 37098180]
  • Anita Vidács, Erika Beáta Kerekes, Miklós Takó, Csaba Vágvölgyi, Judit Krisch. Eradication of multiple-species biofilms from food industrial and domestic surfaces using essential oils. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2023 Mar; ?(?):10820132231165543. doi: 10.1177/10820132231165543. [PMID: 36959708]
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  • Xin Quan, Caiyong Yu, Zhongmin Fan, Tong Wu, Chuchu Qi, Haoying Zhang, Shengxi Wu, Xi Wang. Hydralazine plays an immunomodulation role of pro-regeneration in a mouse model of spinal cord injury. Experimental neurology. 2023 Feb; ?(?):114367. doi: 10.1016/j.expneurol.2023.114367. [PMID: 36858281]
  • Guang Cheng, Jiehong Guo, Renwei Wang, Jian-Min Yuan, Silvia Balbo, Stephen S Hecht. Quantitation by Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai Cohort Study. Chemical research in toxicology. 2023 Feb; 36(2):305-312. doi: 10.1021/acs.chemrestox.2c00393. [PMID: 36719849]
  • Hauh-Jyun Candy Chen. Mass Spectrometry Analysis of DNA and Protein Adducts as Biomarkers in Human Exposure to Cigarette Smoking: Acrolein as an Example. Chemical research in toxicology. 2023 02; 36(2):132-140. doi: 10.1021/acs.chemrestox.2c00354. [PMID: 36626705]
  • Yuanyuan Wang, Maofeng Dong, Limin Guo, Yamin Zhu, Qingqing Jiang, Jianbo Xiao, Mingfu Wang, Yueliang Zhao. Effect of acrolein on the formation of harman and norharman in chemical models and roast beef patties. Food research international (Ottawa, Ont.). 2023 02; 164(?):112465. doi: 10.1016/j.foodres.2023.112465. [PMID: 36738015]
  • Hauh-Jyun Candy Chen, Shu-Wei Cheng, Nai-Ying Chen, Deng-Chyang Wu. Characterization and Quantification of Acrolein-Induced Modifications in Hemoglobin by Mass Spectrometry─Effect of Cigarette Smoking. Chemical research in toxicology. 2022 12; 35(12):2260-2270. doi: 10.1021/acs.chemrestox.2c00262. [PMID: 36367988]
  • Kaihui Chang, Nan Zeng, Yonghe Ding, Xiangzhong Zhao, Chengwen Gao, Yafang Li, Haoxu Wang, Xiaoyu Liu, Yujuan Niu, Yuanchao Sun, Teng Li, Yongyong Shi, Chuanhong Wu, Zhiqiang Li. Cinnamaldehyde causes developmental neurotoxicity in zebrafish via the oxidative stress pathway that is rescued by astaxanthin. Food & function. 2022 Dec; 13(24):13028-13039. doi: 10.1039/d2fo02309a. [PMID: 36449017]
  • Qi Xiao. Cinnamaldehyde attenuates kidney senescence and injury through PI3K/Akt pathway-mediated autophagy via downregulating miR-155. Renal failure. 2022 Dec; 44(1):601-614. doi: 10.1080/0886022x.2022.2056485. [PMID: 35361048]
  • Danni Feng, Zhongxiang Fang, Pangzhen Zhang. The melanin inhibitory effect of plants and phytochemicals: A systematic review. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Dec; 107(?):154449. doi: 10.1016/j.phymed.2022.154449. [PMID: 36126406]
  • Anne Negre-Salvayre, Audrey Swiader, Robert Salvayre, Paul Guerby. Oxidative stress, lipid peroxidation and premature placental senescence in preeclampsia. Archives of biochemistry and biophysics. 2022 11; 730(?):109416. doi: 10.1016/j.abb.2022.109416. [PMID: 36179910]
  • Farah Naz, Mukesh Kumar, Tirthankar Koley, Priyanka Sharma, Muhammad Anzarul Haque, Arti Kapil, Manoj Kumar, Punit Kaur, Abdul Samath Ethayathulla. Screening of plant-based natural compounds as an inhibitor of FtsZ from Salmonella Typhi using the computational, biochemical and in vitro cell-based studies. International journal of biological macromolecules. 2022 Oct; 219(?):428-437. doi: 10.1016/j.ijbiomac.2022.07.241. [PMID: 35932806]
  • Shakeel Ahmad Khan, Ying Wu, Amy Sze-Man Li, Xiu-Qiong Fu, Zhi-Ling Yu. Network pharmacology and molecular docking-based prediction of active compounds and mechanisms of action of Cnidii Fructus in treating atopic dermatitis. BMC complementary medicine and therapies. 2022 Oct; 22(1):275. doi: 10.1186/s12906-022-03734-7. [PMID: 36261841]
  • Sungshim L Park, Loic Le Marchand, Guang Cheng, Silvia Balbo, Menglan Chen, Steven G Carmella, Nicole M Thomson, Younghan Lee, Yesha M Patel, Daniel O Stram, Joni Jensen, Dorothy K Hatsukami, Sharon E Murphy, Stephen S Hecht. Quantitation of DNA Adducts Resulting from Acrolein Exposure and Lipid Peroxidation in Oral Cells of Cigarette Smokers from Three Racial/Ethnic Groups with Differing Risks for Lung Cancer. Chemical research in toxicology. 2022 10; 35(10):1914-1922. doi: 10.1021/acs.chemrestox.2c00171. [PMID: 35998368]
  • Medjda Bellamri, Scott J Walmsley, Christina Brown, Kyle Brandt, Dmitri Konorev, Abderrahman Day, Chia-Fang Wu, Ming Tsang Wu, Robert J Turesky. DNA Damage and Oxidative Stress of Tobacco Smoke Condensate in Human Bladder Epithelial Cells. Chemical research in toxicology. 2022 10; 35(10):1863-1880. doi: 10.1021/acs.chemrestox.2c00153. [PMID: 35877975]
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