myo-Inositol 1-phosphate (BioDeep_00000004604)

 

Secondary id: BioDeep_00000027851, BioDeep_00000171711, BioDeep_00001868776

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid

化学式: C6H13O9P (260.0297)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(feces) 31.42%

分子结构信息

SMILES: C1(C(C(C(C(C1O)O)OP(=O)(O)O)O)O)O
InChI: InChI=1S/C6H13O9P/c7-1-2(8)4(10)6(5(11)3(1)9)15-16(12,13)14/h1-11H,(H2,12,13,14)

描述信息

myo-Inositol 1-phosphate, also known as I1P or ins(1)p, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. myo-Inositol 1-phosphate is a metabolite of inositol phosphate metabolism and the phosphatidylinositol signalling system. Inositol phosphatases (EC:3.1.3.25) play a crucial role in the phosphatidylinositol signalling pathway. Expression is substantially higher in the subcortical regions of the brain, most prominently in the caudate. The phosphatidylinositol pathway is thought to be modified by lithium, a commonly prescribed medication in treating bipolar disorder (OMIM: 605922).
Myo-inositol 1-phosphate is a metabolite of the Inositol phosphate metabolism and the Phosphatidylinositol signaling system. Inositol phosphatases [EC:3.1.3.25] play a crucial role in the phosphatidylinositol signaling pathway; in brain, the expression is substantially higher in the subcortical regions, most prominently in the caudate. The phosphatidylinositol pathway is thought to be modified by lithium, a commonly prescribed medication in treating bipolar disorder. (OMIM 605922) [HMDB]

同义名列表

30 个代谢物同义名

{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid; (2,3,4,5,6-Pentahydroxycyclohexyl) dihydrogen phosphate; 1D-Myo-inositol 1-monophosphoric acid; 1-(Dihydrogen phosphate) myo-inositol; D-myo-inositol-1-hydrogen phosphate; DL-Myoinositol-1-phosphate 2 CHA; 1D-Myo-inositol 1-phosphoric acid; D-Myo-inositol 1-phosphoric acid; 1D-Myo-inositol 1-monophosphate; D-myo-Inositol-1-monophosphate; Myo-inositol 1-phosphoric acid; Myoinositol 1-phosphoric acid; myo-Inositol 1-monophosphate; 1D-myo-Inositol 1-phosphate; D-myo-Inositol-1-phosphate; D-Myo-inositol 1-phosphate; Inositol 1-phosphoric acid; myo-Inositol-1-phosphate; myo-Inositol 1-phosphate; Myoinositol 1-phosphate; Inositophosphoric acid; Inositol monophosphate; Inositol 1-phosphate; Inositol phosphate; Ins(1)P1; Ins(1)p; Ins1p; 1-IP1; IPhC; I1P



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(6)

BioCyc(0)

PlantCyc(0)

代谢反应

52 个相关的代谢反应过程信息。

Reactome(51)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(1)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

52 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AKT1, IKBKG, IPMK, ISYNA1, ITPR3, PRKX
Endoplasmic reticulum membrane 1 ITPR3
Nucleus 5 AKT1, IKBKG, IPMK, PLCZ1, PRKX
cytosol 6 AKT1, AVP, IKBKG, ISYNA1, PLCZ1, PRKCQ
dendrite 1 AVP
nucleoplasm 6 AKT1, IKBKG, IPMK, ITPR3, PLCZ1, PRKX
Cell membrane 4 ADRB3, AGTR1, AKT1, GPRC5A
lamellipodium 1 AKT1
Multi-pass membrane protein 4 ADRB3, AGTR1, GPRC5A, ITPR3
Synapse 1 TAC1
cell cortex 1 AKT1
glutamatergic synapse 1 AKT1
Golgi apparatus 1 NPY
Golgi membrane 1 INS
neuronal cell body 2 ITPR3, TAC1
postsynapse 1 AKT1
Cytoplasmic vesicle, secretory vesicle 1 NTS
plasma membrane 8 ADRB3, AGTR1, AKT1, GPRC5A, GPRIN2, ITPR3, KNG1, PRKCQ
Membrane 3 AGTR1, AKT1, ITPR3
axon 2 CCK, TAC1
brush border 1 ITPR3
extracellular exosome 2 GPRC5A, KNG1
endoplasmic reticulum 1 ITPR3
extracellular space 7 AVP, CCK, GNRH1, INS, KNG1, NPY, TAC1
perinuclear region of cytoplasm 1 PLCZ1
protein-containing complex 2 AKT1, IKBKG
intracellular membrane-bounded organelle 2 GPRC5A, NTS
pronucleus 1 PLCZ1
Secreted 5 AVP, CCK, INS, NPY, NTS
extracellular region 8 AVP, CCK, GNRH1, INS, KNG1, NPY, NTS, TAC1
centriolar satellite 1 PRKCQ
microtubule cytoskeleton 1 AKT1
nucleolus 3 GPRC5A, ITPR3, PLCZ1
apical part of cell 1 ITPR3
cell-cell junction 1 AKT1
vesicle 2 AKT1, GPRC5A
Cytoplasm, perinuclear region 1 PLCZ1
spindle 1 AKT1
GABA-ergic synapse 1 NPY
sarcoplasmic reticulum 1 ITPR3
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 KNG1
secretory granule 1 AVP
nuclear outer membrane 1 ITPR3
receptor complex 3 ADRB3, GPRC5A, ITPR3
ciliary basal body 1 AKT1
mitotic spindle 1 IKBKG
Secreted, extracellular space 1 KNG1
spindle pole 1 IKBKG
blood microparticle 1 KNG1
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 GPRC5A
ubiquitin ligase complex 1 IKBKG
secretory granule lumen 1 INS
secretory granule membrane 1 ITPR3
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, KNG1
platelet alpha granule lumen 1 KNG1
axon terminus 1 NTS
transport vesicle 2 INS, NTS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
neuronal dense core vesicle 2 AVP, NPY
aggresome 1 PRKCQ
IkappaB kinase complex 1 IKBKG
clathrin-coated endocytic vesicle membrane 1 AVP
platelet dense tubular network membrane 1 ITPR3
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 NPY
transport vesicle membrane 1 ITPR3
sperm head 1 PLCZ1
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3


文献列表

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