N-Sulfo-D-glucosamine (BioDeep_00000004562)

 

Secondary id: BioDeep_00001870703

human metabolite Endogenous


代谢物信息卡片


N-[(2R,3R,4R,5S,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)oxan-3-yl]sulphamic acid

化学式: C6H13NO8S (259.0362)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 26.46%

分子结构信息

SMILES: C(C1C(C(C(C(O1)O)NS(=O)(=O)O)O)O)O
InChI: InChI=1S/C6H13NO8S/c8-1-2-4(9)5(10)3(6(11)15-2)7-16(12,13)14/h2-11H,1H2,(H,12,13,14)/t2-,3-,4-,5-,6-/m1/s1

描述信息

N-Sulfo-D-glucosamine is a structurally altered form of N-acetyl-D-glucosamine (a polysaccharide found in animal tissues) by heparan sulfate N-deacetylase /N-sulfotransferase enzymes.
No human references found [HMDB]

同义名列表

7 个代谢物同义名

N-[(2R,3R,4R,5S,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)oxan-3-yl]sulphamic acid; N-[(2R,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]sulfamic acid; N-[(2R,3R,4R,5S,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)oxan-3-yl]sulphamate; N-[(2R,3R,4R,5S,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)oxan-3-yl]sulfamate; 2-deoxy-2-sulfoaminohexose; N-SulphO-D-glucosamine; N-Sulfo-D-glucosamine



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 FGF2, FGFR2, STAB2
Endoplasmic reticulum membrane 1 HMOX2
Nucleus 4 FGF2, FGFR1, FGFR2, HPSE
cytosol 3 FGFR1, GPT, STAB2
nucleoplasm 1 HPSE
Cell membrane 5 FGFR1, FGFR2, GPC3, ITGAM, STAB2
Cytoplasmic side 1 HMOX2
Multi-pass membrane protein 1 ACKR1
cell cortex 1 FGFR2
cell surface 6 FGFR2, GPC3, ITGAM, SDC2, SULF1, SULF2
glutamatergic synapse 1 FGFR1
Golgi apparatus 2 FGFR2, SULF1
lysosomal membrane 1 HPSE
postsynapse 1 FGFR1
Cytoplasm, cytosol 1 FGFR1
Lysosome 4 GALNS, HPSE, IDUA, SGSH
plasma membrane 12 ACKR1, FGFR1, FGFR2, GPC3, HMOX2, ITGAM, SDC2, SERPINC1, STAB1, STAB2, SULF1, SULF2
Membrane 9 ACKR1, FGFR1, FGFR2, HGF, HMOX2, HPSE, ITGAM, SDC2, STAB1
extracellular exosome 6 GALNS, GPT, IDUA, ITGAM, SERPINC1, SGSH
endoplasmic reticulum 2 SULF1, SULF2
extracellular space 8 FGF2, HGF, HPSE, IL10, ITGAM, SERPINC1, SULF1, SULF2
lysosomal lumen 6 GALNS, GPC3, HPSE, IDUA, SDC2, SGSH
intracellular membrane-bounded organelle 1 HPSE
Microsome membrane 1 HMOX2
Single-pass type I membrane protein 6 FGFR1, FGFR2, ITGAM, SDC2, STAB1, STAB2
Secreted 3 FGF2, HPSE, IL10
extracellular region 9 FGF2, FGFR1, FGFR2, GALNS, HGF, HPSE, IL10, SERPINC1, SULF2
excitatory synapse 1 FGFR2
Extracellular side 1 GPC3
external side of plasma membrane 2 ITGAM, STAB2
cytoplasmic vesicle 2 FGFR1, FGFR2
Early endosome 1 ACKR1
recycling endosome 1 ACKR1
Membrane raft 3 HPSE, ITGAM, SULF1
extracellular matrix 1 HPSE
collagen-containing extracellular matrix 3 GPC3, SDC2, SERPINC1
receptor complex 2 FGFR1, FGFR2
Secreted, extracellular space 1 SERPINC1
blood microparticle 1 SERPINC1
Lipid-anchor, GPI-anchor 1 GPC3
specific granule membrane 2 HMOX2, ITGAM
tertiary granule membrane 1 ITGAM
side of membrane 1 GPC3
Golgi stack 2 SULF1, SULF2
plasma membrane raft 1 ITGAM
Golgi lumen 2 GPC3, SDC2
endoplasmic reticulum lumen 3 GPC3, SDC2, SERPINC1
platelet alpha granule lumen 1 HGF
specific granule lumen 1 HPSE
endocytic vesicle membrane 2 STAB1, STAB2
azurophil granule lumen 1 GALNS
Single-pass type IV membrane protein 1 HMOX2
integrin complex 1 ITGAM
integrin alphaM-beta2 complex 1 ITGAM
Golgi apparatus, Golgi stack 2 SULF1, SULF2
[Extracellular sulfatase Sulf-2 secreted form]: Secreted 2 SULF1, SULF2


文献列表

  • M De Wolf, H J Hilderson, A Lagrou, W Dierick. Lipolytic enzymes in bovine thyroid tissue. III. Lysophospholipase activity. Archives internationales de physiologie et de biochimie. 1979 Feb; 87(1):1-18. doi: 10.3109/13813457909070481. [PMID: 92222]
  • K M Lovette, H Y Chuang, A F Mohammad, R G Mason. The subcellular distribution and partial characterization of cholinesterase activities of canine platelets. Biochimica et biophysica acta. 1976 Apr; 428(2):355-68. doi: 10.1016/0304-4165(76)90043-x. [PMID: 6047]
  • A C Buck. Disorders of micturition in bacterial prostatitis. Proceedings of the Royal Society of Medicine. 1975 Aug; 68(8):508-11. doi: NULL. [PMID: 681]