Erythromycin (BioDeep_00000002206)

 

Secondary id: BioDeep_00000397469

human metabolite blood metabolite Chemicals and Drugs Antibiotics natural product


代谢物信息卡片


(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione

化学式: C37H67NO13 (733.4612)
中文名称: 红霉素
谱图信息: 最多检出来源 Homo sapiens(otcml) 14.35%

分子结构信息

SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O
InChI: InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

描述信息

Erythromycin belongs to the class of organic compounds known as xanthines. These are purine derivatives with a ketone group conjugated at carbons 2 and 6 of the purine moiety. Thus, erythromycin is considered to be a macrolide lipid molecule. Erythromycin is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Erythromycin is a macrolide antibiotic produced by Streptomyces erythreus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits; binding inhibits peptidyl transferase activity and interferes with the translocation of amino acids during the translation and assembly of proteins. Erythromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01F - Macrolides, lincosamides and streptogramins > J01FA - Macrolides
D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use > D10AF - Antiinfectives for treatment of acne
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic
D005765 - Gastrointestinal Agents
Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research[3][4].
Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research[3][4].

同义名列表

37 个代谢物同义名

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione; Erythromycin glucoheptonate; Erythromycin Ethylsuccinate; Erythromycin lactobionate; 3-O-Demethylerythromycin; Phosphate, erythromycin; erythromycin phosphate; Lactate, erythromycin; Erythromycin Stearate; Erythromycin lactate; Erythrocin stearate; Erythromycin oxime; C, Erythromycin; Erythromycin a; Erythromycinum; Erythromycin C; Erythromycine; Eritromicina; Erythromycin; Erthromycin; Abomacetin; Akne-mycin; Erythromid; Ilotycin; Staticin; Erycette; Erygel; T Stat; T-Stat; Erymax; TStat; Eryc; Pce; EM; Erythromycin



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

60 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ABCB1, CAT, CYP2C9, CYP3A4, MEFV, MSRA
Endoplasmic reticulum membrane 5 CD4, CYP1A2, CYP2C9, CYP3A4, CYP3A5
Cytoplasmic vesicle, autophagosome 1 MEFV
Nucleus 1 MEFV
autophagosome 1 MEFV
cytosol 5 CAT, LIPE, MEFV, MLNR, MSRA
nucleoplasm 2 MEFV, MSRA
Cell membrane 6 ABCB1, CD4, KCNH2, LIPE, RECK, TNF
Lipid-anchor 1 MSRA
lamellipodium 1 MEFV
Multi-pass membrane protein 3 ABCB1, CACNA1I, KCNH2
cell surface 3 ABCB1, KCNH2, TNF
neuronal cell body 1 TNF
Cytoplasm, cytosol 1 LIPE
plasma membrane 9 ABCB1, CACNA1I, CD4, CYP2C9, KCNH2, MLNR, MSRA, RECK, TNF
Membrane 9 ABCB1, CACNA1I, CAT, CYP3A4, CYP3A5, KCNH2, LIPE, MSRA, RECK
apical plasma membrane 1 ABCB1
caveola 1 LIPE
extracellular exosome 3 ABCB1, CAT, MSRA
extracellular space 4 CRP, CXCL8, IL6, TNF
perinuclear region of cytoplasm 1 KCNH2
mitochondrion 2 CAT, MSRA
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 6 CAT, CYP1A2, CYP2C9, CYP3A4, CYP3A5, MSRA
Microsome membrane 4 CYP1A2, CYP2C9, CYP3A4, CYP3A5
Single-pass type I membrane protein 1 CD4
Secreted 3 CRP, CXCL8, IL6
extracellular region 7 CAT, CRP, CXCL8, IL6, MLN, RECK, TNF
Single-pass membrane protein 1 MLN
mitochondrial matrix 1 CAT
external side of plasma membrane 2 CD4, TNF
actin cytoskeleton 1 MSRA
cytoplasmic vesicle 1 MEFV
Wnt signalosome 1 RECK
midbody 1 MSRA
Early endosome 1 CD4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 ABCB1
Cell projection, lamellipodium 1 MEFV
Membrane raft 2 CD4, TNF
focal adhesion 1 CAT
microtubule 1 MEFV
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Cell projection, ruffle 1 MEFV
ruffle 1 MEFV
microtubule associated complex 1 MEFV
phagocytic cup 1 TNF
Lipid-anchor, GPI-anchor 1 RECK
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
monoatomic ion channel complex 1 KCNH2
side of membrane 1 RECK
inward rectifier potassium channel complex 1 KCNH2
voltage-gated potassium channel complex 1 KCNH2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 CD4, IL6
voltage-gated calcium channel complex 1 CACNA1I
Sarcoplasmic reticulum membrane 1 MLN
clathrin-coated endocytic vesicle membrane 1 CD4
[Isoform 2]: Nucleus 1 MEFV
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cytoplasm, cytoskeleton 1 MEFV
canonical inflammasome complex 1 MEFV
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Hongjie Chen, Charmaine Ng, Ngoc Han Tran, Laurence Haller, Shin Giek Goh, Francis Rathinam Charles, Zhixin Wu, Jit Xin Lim, Karina Yew-Hoong Gin. Removal efficiency of antibiotic residues, antibiotic resistant bacteria, and genes across parallel secondary settling tank and membrane bioreactor treatment trains in a water reclamation plant. The Science of the total environment. 2024 May; 924(?):171723. doi: 10.1016/j.scitotenv.2024.171723. [PMID: 38492595]
  • Yuan-Feng Yan, Ying Liu, Hangeri Liang, Le Cai, Xiao-Yan Yang, Tian-Peng Yin. The erythromycin polyketide compound TMC-154 stimulates ROS generation to exert antibacterial effects against Streptococcus pyogenes. Journal of proteomics. 2024 02; 292(?):105057. doi: 10.1016/j.jprot.2023.105057. [PMID: 38043864]
  • Lingxian Yi, Rui Xu, Xiaowu Yuan, Zining Ren, Huihui Song, Huamin Lai, Zhihua Sun, Hui Deng, Bo Yang, Daojin Yu. Heat stress enhances the occurrence of erythromycin resistance of Enterococcus isolates in mice feces. Journal of thermal biology. 2024 Feb; 120(?):103786. doi: 10.1016/j.jtherbio.2024.103786. [PMID: 38428103]
  • Luu Quynh Huong, Thomas Chisnall, John D Rodgers, Shaun A Cawthraw, Roderick M Card. Prevalence, antibiotic resistance, and genomic characterisation of Campylobacter spp. in retail chicken in Hanoi, Vietnam. Microbial genomics. 2024 Jan; 10(1):. doi: 10.1099/mgen.0.001190. [PMID: 38294872]
  • Nana Zheng, Yuanyuan Xie, Meng Zhou, Yuzhen Liu, Haoxiang Xu, Rong Zeng, Chunping Wan, Min Li. Utilizing the Photodynamic Properties of Curcumin to Disrupt Biofilms in Cutibacterium acnes: A Promising Approach for Treating Acne. Photodiagnosis and photodynamic therapy. 2023 Dec; ?(?):103928. doi: 10.1016/j.pdpdt.2023.103928. [PMID: 38070633]
  • Christine B Georgakakos, Carmen Enid Martínez, Damian E Helbling, M Todd Walter. More movement with manure: increased mobility of erythromycin through agricultural soil in the presence of manure. Journal of water and health. 2023 Sep; 21(9):1143-1157. doi: 10.2166/wh.2023.051. [PMID: 37756186]
  • Haiyan Sun, Xinlou Chai, Guangxun Xu, Shuangying Wei. The Formation and Drug Resistance Mechanism of Biofilm for Streptococcus pneumoniae Infection in Severe Respiratory Patients. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Jan; 69(1):75-80. doi: 10.14715/cmb/2022.69.1.13. [PMID: 37213152]
  • Dhama Al-Sallami, Amjed Alsultan, Kadhim Hassan Abbas, Simon R Clarke. Evaluation of efflux pump inhibitory activity of some plant extracts and using them as adjuvants to potentiate the inhibitory activity of some antibiotics against Staphylococcus aureus. Open veterinary journal. 2023 01; 13(1):42-47. doi: 10.5455/ovj.2023.v13.i1.5. [PMID: 36777436]
  • Jannatul Rumky, Antonina Kruglova, Eveliina Repo. Fate of antibiotic resistance genes (ARGs) in wastewater treatment plant: Preliminary study on identification before and after ultrasonication. Environmental research. 2022 12; 215(Pt 1):114281. doi: 10.1016/j.envres.2022.114281. [PMID: 36096165]
  • Kristina Klobucar, Emily Jardine, Maya A Farha, Marc R MacKinnon, Meghan Fragis, Brenda Nkonge, Timsy Bhando, Louis Borrillo, Caressa N Tsai, Jarrod W Johnson, Brian K Coombes, Jakob Magolan, Eric D Brown. Genetic and Chemical Screening Reveals Targets and Compounds to Potentiate Gram-Positive Antibiotics against Gram-Negative Bacteria. ACS infectious diseases. 2022 10; 8(10):2187-2197. doi: 10.1021/acsinfecdis.2c00357. [PMID: 36098580]
  • Qian Bao, Yichen Wang, Shenghua Tang, Feiyang Ye, Zhiyang Yu, Qingfu Ye, Wei Wang. Uptake and accumulation of erythromycin in leafy vegetables and induced phytotoxicity and dietary risks. The Science of the total environment. 2022 Jul; 830(?):154785. doi: 10.1016/j.scitotenv.2022.154785. [PMID: 35346705]
  • Baiyuan Li, Dan Chen, Fan Lin, Chuanyu Wu, Linyan Cao, Huahai Chen, Yunfei Hu, Yeshi Yin. Genomic Island-Mediated Horizontal Transfer of the Erythromycin Resistance Gene erm(X) among Bifidobacteria. Applied and environmental microbiology. 2022 05; 88(10):e0041022. doi: 10.1128/aem.00410-22. [PMID: 35477272]
  • Dahang Shen, Xin Gu, Yaoying Zheng, Laura Delgado-Moreno, Weibin Jia, Qingfu Ye, Wei Wang. The fate of erythromycin in soils and its effect on soil microbial community structure. The Science of the total environment. 2022 May; 820(?):153373. doi: 10.1016/j.scitotenv.2022.153373. [PMID: 35081411]
  • Zhifeng Liu, Jianlin Xu, Haili Liu, Yong Wang. Engineered EryF hydroxylase improving heterologous polyketide erythronolide B production in Escherichia coli. Microbial biotechnology. 2022 05; 15(5):1598-1609. doi: 10.1111/1751-7915.14000. [PMID: 35174640]
  • Shahid Ahmad Padder, Rauoof Ahmad Rather, Sajad Ahmad Bhat, M D Shah, Tawseef Rehman Baba, N M Mubarak. Dynamics, phylogeny and phyto-stimulating potential of chitinase synthesizing bacterial root endosymbiosiome of North Western Himalayan Brassica rapa L. Scientific reports. 2022 04; 12(1):6742. doi: 10.1038/s41598-022-11030-0. [PMID: 35468936]
  • Zainab A Ibrahim, Shereen F Gheida, Amira R El-Halaby, Ghada F R Hassan, Dareen A Mohammed. Platelet rich plasma injection versus topical erythromycin 2\% in treatment of acne vulgaris. The Journal of dermatological treatment. 2022 Mar; 33(2):946-953. doi: 10.1080/09546634.2020.1793884. [PMID: 32643473]
  • Xin Wen, Cong Shen, Jinyu Xia, Lan-Lan Zhong, Zhongwen Wu, Mohamed Abd El-Gawad El-Sayed Ahmed, Nana Long, Furong Ma, Guili Zhang, Wenwei Wu, Jianlve Luo, Yong Xia, Min Dai, Liyan Zhang, Kang Liao, Siyuan Feng, Cha Chen, Yishen Chen, Wenji Luo, Guo-Bao Tian. Whole-Genome Sequencing Reveals the High Nosocomial Transmission and Antimicrobial Resistance of Clostridioides difficile in a Single Center in China, a Four-Year Retrospective Study. Microbiology spectrum. 2022 02; 10(1):e0132221. doi: 10.1128/spectrum.01322-21. [PMID: 35019676]
  • Kadri Adel, Mosbah Amor, Redissi Alaeddine, Noumi Emira, Alreshidi Mousa, Aouadi Kaïss, Ghannay Siwar, Siddiqui Arif Jamal, Adnan Mohd, Vincenzo De Feo, Snoussi Mejdi. Comparative Computational Analysis of Dirithromycin and Azithromycin in Search for a Potent Drug against COVID-19 caused by SARS-CoV-2: Evidence from molecular docking and dynamic simulation. Cellular and molecular biology (Noisy-le-Grand, France). 2022 Feb; 67(5):371-386. doi: 10.14715/cmb/2021.67.5.50. [PMID: 35818230]
  • Zhili Luo, Zhenyang Yu, Daqiang Yin. Obesogenic effect of erythromycin on Caenorhabditis elegans through over-eating and lipid metabolism disturbances. Environmental pollution (Barking, Essex : 1987). 2022 Feb; 294(?):118615. doi: 10.1016/j.envpol.2021.118615. [PMID: 34863891]
  • Laura Molenaar-Kuijsten, C Louwrens Braal, Stefanie L Groenland, Niels de Vries, Hilde Rosing, Jos H Beijnen, Stijn L W Koolen, Annelie J E Vulink, Marloes G J van Dongen, Ron H J Mathijssen, Alwin D R Huitema, Neeltje Steeghs. Effects of the Moderate CYP3A4 Inhibitor Erythromycin on the Pharmacokinetics of Palbociclib: A Randomized Crossover Trial in Patients With Breast Cancer. Clinical pharmacology and therapeutics. 2022 02; 111(2):477-484. doi: 10.1002/cpt.2455. [PMID: 34674222]
  • Camila Silva Rocha, Leticia Yoshie Kochi, Gabriela Breternitz Ribeiro, Daiane Cristina Rocha, Daniella Nogueira Moraes Carneiro, Marcelo Pedrosa Gomes. Evaluating aquatic macrophytes for removing erythromycin from contaminated water: floating or submerged?. International journal of phytoremediation. 2022; 24(9):995-1003. doi: 10.1080/15226514.2021.1991268. [PMID: 34686072]
  • Maoge Zang, Felise G Adams, Karl A Hassan, Bart A Eijkelkamp. The Impact of Omega-3 Fatty Acids on the Evolution of Acinetobacter baumannii Drug Resistance. Microbiology spectrum. 2021 12; 9(3):e0145521. doi: 10.1128/spectrum.01455-21. [PMID: 34762519]
  • Daniel Aparecido da Silva Rodrigues, Camila Cristina Rodrigues Ferreira da Cunha, Daiana Rocha do Espirito Santo, André Luis Corrêa de Barros, Andressa Rezende Pereira, Silvana de Queiroz Silva, Aníbal da Fonseca Santiago, Robson José de Cássia Franco Afonso. Removal of cephalexin and erythromycin antibiotics, and their resistance genes, by microalgae-bacteria consortium from wastewater treatment plant secondary effluents. Environmental science and pollution research international. 2021 Dec; 28(47):67822-67832. doi: 10.1007/s11356-021-15351-x. [PMID: 34268682]
  • Li-Ping Han, Han-Yan Xiao, Li-Li Fang. A retrospective study of azithromycin and ceftizoxime for the management of children with Mycoplasma pneumoniae pneumonia. Medicine. 2021 Nov; 100(44):e27564. doi: 10.1097/md.0000000000027564. [PMID: 34871221]
  • Lisa Maier, Camille V Goemans, Jakob Wirbel, Michael Kuhn, Claudia Eberl, Mihaela Pruteanu, Patrick Müller, Sarela Garcia-Santamarina, Elisabetta Cacace, Boyao Zhang, Cordula Gekeler, Tisya Banerjee, Exene Erin Anderson, Alessio Milanese, Ulrike Löber, Sofia K Forslund, Kiran Raosaheb Patil, Michael Zimmermann, Bärbel Stecher, Georg Zeller, Peer Bork, Athanasios Typas. Unravelling the collateral damage of antibiotics on gut bacteria. Nature. 2021 11; 599(7883):120-124. doi: 10.1038/s41586-021-03986-2. [PMID: 34646011]
  • Meimei Lai, Tao Ai, Shuzhe Yang, Yongqiong Wei, Yao Deng, Xia Yu, Lei Zhang. The Value of High-Sensitivity C-reactive Protein in Evaluating Myocardial Damage and the Prognosis in Children with Mycoplasmal Pneumonia. Annals of clinical and laboratory science. 2021 Sep; 51(5):721-725. doi: NULL. [PMID: 34686516]
  • Yoko Franchetti, Thomas D Nolin. Application of Individualized PBPK Modeling of Rate Data to Evaluate the Effect of Hemodialysis on Nonrenal Clearance Pathways. Journal of clinical pharmacology. 2021 06; 61(6):769-781. doi: 10.1002/jcph.1818. [PMID: 33459400]
  • Jing Zhang, Zhenyang Yu, Jiaying Shen, Laura N Vandenberg, Daqiang Yin. Influences of sex, rhythm and generation on the obesogenic potential of erythromycin to Drosophila melanogaster. The Science of the total environment. 2021 Jun; 771(?):145315. doi: 10.1016/j.scitotenv.2021.145315. [PMID: 33548709]
  • Zhenjie Huang, Peng Wei, Luoman Gan, Wentao Li, Tonghua Zeng, Caicheng Qin, Zhiyu Chen, Guangnan Liu. Protective effects of different anti‑inflammatory drugs on tracheal stenosis following injury and potential mechanisms. Molecular medicine reports. 2021 May; 23(5):. doi: 10.3892/mmr.2021.11953. [PMID: 34240225]
  • Yang Pu, Jie Pan, Yuan Yao, Wing Yui Ngan, Yang Yang, Meng Li, Olivier Habimana. Ecotoxicological effects of erythromycin on a multispecies biofilm model, revealed by metagenomic and metabolomic approaches. Environmental pollution (Barking, Essex : 1987). 2021 May; 276(?):116737. doi: 10.1016/j.envpol.2021.116737. [PMID: 33618119]
  • Xiaotong Wang, Xiang Dou, Jiangyue Wu, Fanping Meng. Attenuation pathways of erythromycin and biochemical responses related to algal growth and lipid synthesis in a microalga-effluent system. Environmental research. 2021 04; 195(?):110873. doi: 10.1016/j.envres.2021.110873. [PMID: 33582131]
  • M R El-Aassar, Omar M Ibrahim, Moustafa M G Fouda, Hala Fakhry, Jamaan Ajarem, Saleh N Maodaa, Ahmed A Allam, Elsayed E Hafez. Wound dressing of chitosan-based-crosslinked gelatin/ polyvinyl pyrrolidone embedded silver nanoparticles, for targeting multidrug resistance microbes. Carbohydrate polymers. 2021 Mar; 255(?):117484. doi: 10.1016/j.carbpol.2020.117484. [PMID: 33436244]
  • Osatohanmwen J Enogieru, Megan L Koleske, Bianca Vora, Huy Ngo, Sook Wah Yee, Derrick Chatad, Marina Sirota, Kathleen M Giacomini. The Effects of Genetic Mutations and Drugs on the Activity of the Thiamine Transporter, SLC19A2. The AAPS journal. 2021 03; 23(2):35. doi: 10.1208/s12248-021-00562-4. [PMID: 33649974]
  • B Vidal-Veuthey, R Jara, K Santander, A Mella, S Ruiz, L Collado. Antimicrobial resistance and virulence genes profiles of Arcobacter butzleri strains isolated from back yard chickens and retail poultry meat in Chile. Letters in applied microbiology. 2021 Feb; 72(2):126-132. doi: 10.1111/lam.13404. [PMID: 33025583]
  • C Liu, H Huang, Q Zhou, B Liu, Y Wang, P Li, K Liao, W Su. Pithecellobium clypearia extract enriched in gallic acid and luteolin has antibacterial activity against MRSA and reduces resistance to erythromycin, ceftriaxone sodium and levofloxacin. Journal of applied microbiology. 2020 Oct; 129(4):848-859. doi: 10.1111/jam.14668. [PMID: 32301544]
  • Amir Mersa, Saman Atashbar, Negar Ahvar, Ahmad Salimi. 1,25-dihydroxyvitamin D3 prevents deleterious effects of erythromycin on mitochondrial function in rat heart isolated mitochondria. Clinical and experimental pharmacology & physiology. 2020 09; 47(9):1554-1563. doi: 10.1111/1440-1681.13328. [PMID: 32314438]
  • Murilo Henrique M Facure, Rodrigo Schneider, Danilo M Dos Santos, Daniel S Correa. Impedimetric electronic tongue based on molybdenum disulfide and graphene oxide for monitoring antibiotics in liquid media. Talanta. 2020 Sep; 217(?):121039. doi: 10.1016/j.talanta.2020.121039. [PMID: 32498857]
  • Jiangfei Chen, Suhang Guo, Xianzhu Yu, Jinxiu Lei, Tao Xu, Suyan Zhu, Lu Chen, Ping Xu, Xuan Zhou, Lushan Yu. Metabolic interactions between flumatinib and the CYP3A4 inhibitors erythromycin, cyclosporine, and voriconazole. Die Pharmazie. 2020 09; 75(9):424-429. doi: 10.1691/ph.2020.0068. [PMID: 32797767]
  • Kenneth A Johnson. New Strategies for Bone Infection Management. Veterinary and comparative orthopaedics and traumatology : V.C.O.T. 2020 07; 33(4):v. doi: 10.1055/s-0040-1714294. [PMID: 32688429]
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