Thyrotropin releasing hormone (BioDeep_00000001466)

 

Secondary id: BioDeep_00000412685

human metabolite BioNovoGene_Lab2019


代谢物信息卡片


(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

化学式: C16H22N6O4 (362.1702)
中文名称: 转铁蛋白, 促甲状腺素释放激素, 普罗瑞林, 丙肝素
谱图信息: 最多检出来源 Homo sapiens(general) 2.52%

分子结构信息

SMILES: C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)N
InChI: InChI=1S/C16H22N6O4/c17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10/h7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25)/t10-,11-,12-/m0/s1

描述信息

Thyrotropin-releasing hormone (TRH), also called thyrotropin-releasing factor (TRF), thyroliberin or protirelin, is a tripeptide hormone that stimulates the release of thyroid-stimulating hormone and prolactin by the anterior pituitary. In humans, it also acts as a prolactin-releasing factor. It is also a neurotransmitter in the central nervous system. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets. Medical preparations of TRH are used in diagnostic tests of thyroid disorders and in acromegaly. [HMDB]
This compound belongs to the family of N-acyl-alpha Amino Acids and Derivatives. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom.
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C76367 - Thyrotropin-Releasing Hormone Analogue
V - Various > V04 - Diagnostic agents > V04C - Other diagnostic agents > V04CJ - Tests for thyreoidea function
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
KEIO_ID G117; [MS2] KO008963
KEIO_ID G117
Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.

同义名列表

74 个代谢物同义名

(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide; (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide; (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2; Thyroid-stimulating hormone-releasing factor; L-Pyroglutamyl-L-histidyl-L-proline amide; L-Pyroglutamyl-L-histidyl-L-prolineamide; L-Pyroglutamyl-L-histidyl-L-prolinamide; Synthetic thyrotropin-releasing hormone; Synthetic thyrotropin-releasing factor; Thyrotropin releasing hormone tartrate; Thyrotropin-releasing hormone tartrate; Thyrotropic hormone-releasing hormone; Thyrotropic hormone-releasing factor; Thyrotropin-releasing factor (8CI); Henning berlin brand OF protirelin; Synthetic TSH-releasing hormone; Synthetic TSH-releasing factor; Thyrotropin releasing hormone; Thyrotropin-releasing hormone; Thyrotropic releasing hormone; Thyrotropic-releasing factor; Thyrotropin releasing factor; Thyrotropin-releasing factor; Hydrate, proterelin tartrate; Tartrate hydrate, proterelin; Novartis brand OF protirelin; Ferring brand OF protirelin; Aventis brand OF protirelin; Proterelin tartrate hydrate; Abbott brand OF protirelin; Thyroid releasing hormone; Protirelin novartis brand; Protirelin tartrate (1:1); Merck brand OF protirelin; Protirelin aventis brand; Protirelin ferring brand; Protirelin abbott brand; Thyroliberin TRH merck; Protirelin (JP15/USAN); Protirelin merck brand; TSH-Releasing hormone; TSH-Releasing factor; Proterelin tartrate; Relefact TRH (TN); holo-transferrin; Synthetic TRF; TRH, Relefact; Synthetic TRH; Thyroliberin; Abbott 38579; Abbott-38579; Relefact TRH; Rifathyroin; Abbott38579; Rifotironin; TRH Ferring; Protirelin; Lopremone; Prem, TRH; Thypinone; Thyrefact; Stimu TSH; Stimu-TSH; StimuTSH; TRH Prem; Antepan; TSH-RF; PREM; TRH; TRF; Protirelin; Protirelin; Thyrotropin-releasing-hormone; Thyrotropin-releasing hormone



数据库引用编号

38 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 POMC, PREP, PRL, TSHB
Peripheral membrane protein 1 ACHE
Nucleus 4 ACHE, PLCZ1, PREP, PRL
cytosol 4 PLCZ1, PREP, PRKCQ, SST
nucleoplasm 2 PLCZ1, PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 2 ACHE, TRHR
Multi-pass membrane protein 1 TRHR
Synapse 3 ACHE, CRH, TAC1
cell surface 1 ACHE
Golgi apparatus 1 ACHE
Golgi membrane 1 INS
neuromuscular junction 1 ACHE
neuronal cell body 2 SST, TAC1
Cytoplasmic vesicle, secretory vesicle 1 NTS
Lysosome 1 CTSA
plasma membrane 4 ACHE, KNG1, PRKCQ, TRHR
Membrane 3 ACHE, CTSA, PREP
axon 1 TAC1
extracellular exosome 3 CTSA, KNG1, PEPD
endoplasmic reticulum 1 CTSA
extracellular space 11 ACHE, CRH, GH1, INS, KNG1, POMC, PRL, SST, TAC1, TG, TSHB
lysosomal lumen 1 CTSA
perinuclear region of cytoplasm 2 ACHE, PLCZ1
mitochondrion 1 PREP
intracellular membrane-bounded organelle 2 CTSA, NTS
pronucleus 1 PLCZ1
Secreted 12 ACHE, CRH, GH1, INS, NTS, POMC, PRL, SST, TG, TRH, TSHB, VIP
extracellular region 15 ACHE, CRH, CTSA, GH1, INS, KNG1, NTS, POMC, PRL, SST, TAC1, TG, TRH, TSHB, VIP
Mitochondrion matrix 1 PREP
mitochondrial matrix 1 PREP
Extracellular side 1 ACHE
centriolar satellite 1 PRKCQ
varicosity 1 CRH
neuronal dense core vesicle lumen 1 CRH
perikaryon 1 CRH
nucleolus 1 PLCZ1
Cytoplasm, perinuclear region 1 PLCZ1
GABA-ergic synapse 1 SST
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 KNG1
secretory granule 2 POMC, TRH
neuron projection 1 VIP
chromatin 1 PRL
Secreted, extracellular space 1 KNG1
blood microparticle 1 KNG1
Lipid-anchor, GPI-anchor 1 ACHE
endosome lumen 3 GH1, INS, PRL
side of membrane 1 ACHE
secretory granule lumen 2 INS, POMC
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, KNG1
platelet alpha granule lumen 1 KNG1
axon terminus 1 NTS
transport vesicle 2 INS, NTS
azurophil granule lumen 1 CTSA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
neuronal dense core vesicle 1 SST
aggresome 1 PRKCQ
synaptic cleft 1 ACHE
growth hormone receptor complex 1 GH1
sperm head 1 PLCZ1
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • Ren-Dan Zhang, Shi-Qin Jiang, Feng-Juan Yan, Lei Ruan, Cun-Tai Zhang, Xiao-Qing Quan. The association of prealbumin, transferrin, and albumin with immunosenescence among elderly males. The aging male : the official journal of the International Society for the Study of the Aging Male. 2024 Dec; 27(1):2310308. doi: 10.1080/13685538.2024.2310308. [PMID: 38317318]
  • Linghong Sun, Zhengkun Chen, Liping Guo, Zhaoyu Geng, Xingyong Chen. Proteomic Analysis of Egg Yolk Proteins During Embryonic Development in Wanxi White Goose. Journal of agricultural and food chemistry. 2024 Mar; 72(10):5212-5221. doi: 10.1021/acs.jafc.3c07962. [PMID: 38433387]
  • Jaroslaw Szponar, Agnieszka Gorska, Marta Ostrowska-Lesko, Agnieszka Korga-Plewko, Michal Tchorz, Erwin Ciechanski, Anna Dabrowska, Ewa Poleszak, Franciszek Burdan, Jaroslaw Dudka, Marek Murias, Slawomir Mandziuk. Assessment of the Impact of Carvedilol Administered Together with Dexrazoxan and Doxorubicin on Liver Structure and Function, Iron Metabolism, and Myocardial Redox System in Rats. International journal of molecular sciences. 2024 Feb; 25(4):. doi: 10.3390/ijms25042219. [PMID: 38396896]
  • Vanesa Mattera, Federico Occhiuzzi, Jorge Correale, Juana M Pasquini. Remyelinating effect driven by transferrin-loaded extracellular vesicles. Glia. 2024 Feb; 72(2):338-361. doi: 10.1002/glia.24478. [PMID: 37860913]
  • Kexin Sun, Jie V Zhao, Edmund Anthony Severn Nelson, Vincent Wai Sun Wong, Hugh Simon Hung San Lam, Lai Ling Hui. Iron status and non-alcoholic fatty liver disease: A Mendelian randomization study. Nutrition (Burbank, Los Angeles County, Calif.). 2024 Feb; 118(?):112295. doi: 10.1016/j.nut.2023.112295. [PMID: 38103266]
  • Mohd Shahnawaz Khan, Mohammad Furkan, Moyad Shahwan, Dharmendra Kumar Yadav, Saleha Anwar, Rizwan Hasan Khan, Anas Shamsi. Investigating molecular interactions between human transferrin and resveratrol through a unified experimental and computational approach: Role of natural compounds in Alzheimer's disease therapeutics. Amino acids. 2023 Dec; 55(12):1923-1935. doi: 10.1007/s00726-023-03355-5. [PMID: 37926707]
  • Honorato Ortiz-Marrón, Gloria Cabañas Pujadas, Encarnación Donoso Navarro, Mar Burreros García, María Isabel Herreros Álvaro, Alma María Mejía Fernández de Velasco, Ana Cornejo Gutiérrez, Iñaki Galán. Association between biomarkers of iron status and cardiometabolic risk in Spanish children aged 9-10 years. The ELOIN study. European journal of pediatrics. 2023 Dec; 182(12):5649-5659. doi: 10.1007/s00431-023-05244-1. [PMID: 37819420]
  • Xinyuan Wang, Yujie Zhou, Lijun Ning, Jinnan Chen, Huimin Chen, Xiaobo Li. Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer. Cell death & disease. 2023 09; 14(9):588. doi: 10.1038/s41419-023-06114-2. [PMID: 37666806]
  • Xinggang Fang, Zhuo Chen, Wenhui Zhou, Tongfei Li, Man Wang, Yujiu Gao, Shinan Ma, Ying Feng, Shiming Du, Peimin Lan, Hanyu Chen, Jiarui Wei, Sisi Zhang, Zixiang Li, Xinglin Liu, Hongbo Zhang, Xingrong Guo, Jie Luo. Boosting Glioblastoma Therapy with Targeted Pyroptosis Induction. Small (Weinheim an der Bergstrasse, Germany). 2023 07; 19(30):e2207604. doi: 10.1002/smll.202207604. [PMID: 37066699]
  • Wenjie Chen, Li Xie, Can Lv, Erqun Song, Xiaokang Zhu, Yang Song. Transferrin-Targeted Cascade Nanoplatform for Inhibiting Transcription Factor Nuclear Factor Erythroid 2-Related Factor 2 and Enhancing Ferroptosis Anticancer Therapy. ACS applied materials & interfaces. 2023 Jun; 15(24):28879-28890. doi: 10.1021/acsami.3c01499. [PMID: 37249181]
  • Jianan Wang, Shiying Liu, Yalei Xie, Chengli Xu. Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m. Scientific reports. 2023 06; 13(1):9225. doi: 10.1038/s41598-023-35573-y. [PMID: 37286697]
  • Yeyang Wang, Wenjun Li, Mingsen Wang, Hongdong Chen, Yongsheng Li, Wei Wei, Xuhua Liu, Yuelin Wu, Sidong Luo, Xinfang Liu, Man Xiong. Quercetin prevents the ferroptosis of OPCs by inhibiting the Id2/transferrin pathway. Chemico-biological interactions. 2023 May; ?(?):110556. doi: 10.1016/j.cbi.2023.110556. [PMID: 37230155]
  • Dongju Lee, Euncheol Son, Young-Hoon Kim. Transferrin-mediated increase of labile iron Pool following simulated ischemia causes lipid peroxidation during the early phase of reperfusion. Free radical research. 2023 Feb; ?(?):1-17. doi: 10.1080/10715762.2023.2169683. [PMID: 36794395]
  • Carolina Griselda Luchetti, María Soledad Lorenzo, Evelin Mariel Elia, Gabriela Maia Teplitz, Paula Romina Cruzans, María Clara Carou, Daniel Marcelo Lombardo. Effects of the addition of insulin-transferrin-selenium (ITS) and/or metformin to the in vitro maturation of porcine oocytes on cytoplasmic maturation and embryo development. Reproduction, fertility, and development. 2023 Feb; ?(?):. doi: 10.1071/rd22254. [PMID: 36780707]
  • Puja Sandbhor, Jayant Goda, Bhabani Mohanty, Poonam Gera, Sandhya Yadav, Godanjali Chekuri, Pradip Chaudhari, Shilpee Dutt, Rinti Banerjee. Targeted nano-delivery of chemotherapy via intranasal route suppresses in vivo glioblastoma growth and prolongs survival in the intracranial mouse model. Drug delivery and translational research. 2023 02; 13(2):608-626. doi: 10.1007/s13346-022-01220-8. [PMID: 36245060]
  • Yunjia Li, Mengchen Qin, Weichao Zhong, Chang Liu, Guanghui Deng, Menghan Yang, Junjie Li, Haixin Ye, Hao Shi, Chaofeng Wu, Haiyan Lin, Yuyao Chen, Shaohui Huang, Chuying Zhou, Zhiping Lv, Lei Gao. RAGE promotes dysregulation of iron and lipid metabolism in alcoholic liver disease. Redox biology. 2023 02; 59(?):102559. doi: 10.1016/j.redox.2022.102559. [PMID: 36502724]
  • Yuanyuan Zhu, Wei Zhang, Jing Chen. Binary Nanodrug-Delivery System Designed for Leukemia Therapy: Aptamer- and Transferrin-Codecorated Daunorubicin- and Luteolin-Coloaded Nanoparticles. Drug design, development and therapy. 2023; 17(?):1-13. doi: 10.2147/dddt.s387246. [PMID: 36636745]
  • Yuto Arai, Tohru Okanishi, Sotaro Kanai, Tetsuya Okazaki, Eriko Koshimizu, Satoko Miyatake, Yukinori Maeoka, Ayataka Fujimoto, Naomichi Matsumoto, Yoshihiro Maegaki. A case of ALG11-congenital disorders of glycosylation diagnosed by post-mortem whole exome sequencing. Brain & development. 2022 Nov; 44(10):732-736. doi: 10.1016/j.braindev.2022.07.005. [PMID: 35907674]
  • Zhuangzhuang Liu, Sujuan Ding, Hongmei Jiang, Jun Fang. Egg Protein Transferrin-Derived Peptides Irw (Lle-Arg-Trp) and Iqw (Lle-Gln-Trp) Prevent Obesity Mouse Model Induced by a High-Fat Diet via Reducing Lipid Deposition and Reprogramming Gut Microbiota. International journal of molecular sciences. 2022 Sep; 23(19):. doi: 10.3390/ijms231911227. [PMID: 36232527]
  • Guangming Gong, Wenhui Qian, Luzhong Zhang, Jia Jia, Jinbing Xie, Qing Zhu, Wenya Liu, Pin Tu, Ming Gao, Liang Zhang, Haiqing Tang, Hua Su, Kaifeng Wei, Changshen Zhou, Kai Kai Wang, Qinqin Pan. A curcumin-induced assembly of a transferrin nanocarrier system and its antitumor effect. Colloids and surfaces. B, Biointerfaces. 2022 Sep; 217(?):112613. doi: 10.1016/j.colsurfb.2022.112613. [PMID: 35816883]
  • Taslima Gani Khan, David Ginsburg, Brian T Emmer. The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes. Journal of lipid research. 2022 08; 63(8):100248. doi: 10.1016/j.jlr.2022.100248. [PMID: 35753407]
  • Sara Baldassano, Maria Rita Polizzi, Leo Sabatino, Rosalia Caldarella, Andrea Macaluso, Angelina Alongi, Gaetano Felice Caldara, Vincenzo Ferrantelli, Sonya Vasto. A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables. Nutrients. 2022 Jul; 14(14):. doi: 10.3390/nu14142971. [PMID: 35889926]
  • Güldeniz Şekerci, Yavuz Erden, Suat Tekin. Effects of meteorin-like hormone on endocrine function of hypothalamo-hypophysial system and peripheral uncoupling proteins in rats. Molecular biology reports. 2022 Jul; 49(7):5919-5925. doi: 10.1007/s11033-022-07374-5. [PMID: 35332411]
  • Bin Xue, Debarati DasGupta, Manzar Alam, Mohd Shahnawaz Khan, Shuo Wang, Anas Shamsi, Asimul Islam, Md Imtaiyaz Hassan. Investigating binding mechanism of thymoquinone to human transferrin, targeting Alzheimer's disease therapy. Journal of cellular biochemistry. 2022 Jun; ?(?):. doi: 10.1002/jcb.30299. [PMID: 35722728]
  • Min Shao, Qi Jiang, Chao Shen, Zhong Liu, Lihong Qiu. Sinapine induced ferroptosis in non-small cell lung cancer cells by upregulating transferrin/transferrin receptor and downregulating SLC7A11. Gene. 2022 Jun; 827(?):146460. doi: 10.1016/j.gene.2022.146460. [PMID: 35358657]
  • Teoman Benli-Hoppe, Şurhan Göl Öztürk, Özgür Öztürk, Simone Berger, Ernst Wagner, Mina Yazdi. Transferrin Receptor Targeted Polyplexes Completely Comprised of Sequence-Defined Components. Macromolecular rapid communications. 2022 Jun; 43(12):e2100602. doi: 10.1002/marc.202100602. [PMID: 34713524]
  • Fatemeh Khonsari, Mostafa Heydari, Mohammad Sharifzadeh, Hadi Valizadeh, Rassoul Dinarvand, Fatemeh Atyabi. Transferrin decorated-nanostructured lipid carriers (NLCs) are a promising delivery system for rapamycin in Alzheimer's disease: An in vivo study. Biomaterials advances. 2022 Jun; 137(?):212827. doi: 10.1016/j.bioadv.2022.212827. [PMID: 35929260]
  • Shuhua Fan, Qiangqiang Yang, Qianna Song, Min Hong, Xiaoyan Liu, Haobin Chen, Juan Wang, Chuan Li, Shuang Cheng. Multi-pathway inducing ferroptosis by MnO2-based nanodrugs for targeted cancer therapy. Chemical communications (Cambridge, England). 2022 Jun; 58(45):6486-6489. doi: 10.1039/d2cc02134j. [PMID: 35551311]
  • Jelena Jankovic Miljus, María Augusta Guillén-Sacoto, Jennifer Makiadi-Alvarado, León Wert-Lamas, Julia Ramirez-Moya, Mercedes Robledo, Pilar Santisteban, Garcilaso Riesco-Eizaguirre. Circulating MicroRNA Profiles as Potential Biomarkers for Differentiated Thyroid Cancer Recurrence. The Journal of clinical endocrinology and metabolism. 2022 04; 107(5):1280-1293. doi: 10.1210/clinem/dgac009. [PMID: 35022762]
  • Kristen Thane, Cassandra Uricchio, Nicholas Frank. Effect of early or late blood sampling on thyrotropin releasing hormone stimulation test results in horses. Journal of veterinary internal medicine. 2022 Mar; 36(2):770-777. doi: 10.1111/jvim.16362. [PMID: 35049089]
  • Prasath Paramasivam, Christian Franke, Martin Stöter, Andreas Höijer, Stefano Bartesaghi, Alan Sabirsh, Lennart Lindfors, Marianna Yanez Arteta, Anders Dahlén, Annette Bak, Shalini Andersson, Yannis Kalaidzidis, Marc Bickle, Marino Zerial. Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale. The Journal of cell biology. 2022 02; 221(2):. doi: 10.1083/jcb.202110137. [PMID: 34882187]
  • Yuri Kondo, Atsushi Ozawa, Daisuke Kohno, Kazuma Saito, Battsetseg Buyandalai, Sayaka Yamada, Kazuhiko Horiguchi, Yasuyo Nakajima, Nobuyuki Shibusawa, Akihiro Harada, Hideaki Yokoo, Hideo Akiyama, Tsutomu Sasaki, Tadahiro Kitamura, Masanobu Yamada. The Hypothalamic Paraventricular Nucleus Is the Center of the Hypothalamic-Pituitary-Thyroid Axis for Regulating Thyroid Hormone Levels. Thyroid : official journal of the American Thyroid Association. 2022 01; 32(1):105-114. doi: 10.1089/thy.2021.0444. [PMID: 34726513]
  • Qi Zhou, Kezhu Hou, Zhiqiang Fu. Transferrin-Modified Mangiferin-Loaded SLNs: Preparation, Characterization, and Application in A549 Lung Cancer Cell. Drug design, development and therapy. 2022; 16(?):1767-1778. doi: 10.2147/dddt.s366531. [PMID: 35707686]
  • Intouch Sakpakdeejaroen, Patcharaporn Muanrit, Sumalee Panthong, Srisopa Ruangnoo. Alpha-Mangostin-Loaded Transferrin-Conjugated Lipid-Polymer Hybrid Nanoparticles: Development and Characterization for Tumor-Targeted Delivery. TheScientificWorldJournal. 2022; 2022(?):9217268. doi: 10.1155/2022/9217268. [PMID: 36081606]
  • Puja Sandbhor, Jayant Goda, Bhabani Mohanty, Pradip Chaudhari, Shilpee Dutt, Rinti Banerjee. Non-invasive transferrin targeted nanovesicles sensitize resistant glioblastoma multiforme tumors and improve survival in orthotopic mouse models. Nanoscale. 2021 Dec; 14(1):108-126. doi: 10.1039/d1nr05460k. [PMID: 34897360]
  • Valentina Valenzuela-Muñoz, Bárbara P Benavente, Antonio Casuso, Yeny Leal, Diego Valenzuela-Miranda, Gustavo Núñez-Acuña, Constanza Sáez-Vera, Cristian Gallardo-Escárate. Transcriptome and morphological analysis in Caligus rogercresseyi uncover the effects of Atlantic salmon vaccination with IPath®. Fish & shellfish immunology. 2021 Oct; 117(?):169-178. doi: 10.1016/j.fsi.2021.08.005. [PMID: 34389379]
  • Jie Li, Huamin Zeng, Yu You, Rongrong Wang, Tiantian Tan, Weiming Wang, Liyan Yin, Zhaowu Zeng, Yiying Zeng, Tian Xie. Active targeting of orthotopic glioma using biomimetic liposomes co-loaded elemene and cabazitaxel modified by transferritin. Journal of nanobiotechnology. 2021 Sep; 19(1):289. doi: 10.1186/s12951-021-01048-3. [PMID: 34565383]
  • Rie Kanamori, Shiho Yamane, Takeshi Seto. Long-Term Safety and Effectiveness of Thyrotropin Alfa in Japanese Patients: A Post-Marketing Surveillance Study. Advances in therapy. 2021 09; 38(9):4949-4960. doi: 10.1007/s12325-021-01866-9. [PMID: 34386895]
  • Xuerong Dong, Xiang Zhang, Manyuan Wang, Liwei Gu, Jing Li, Muxin Gong. Heparin-decorated nanostructured lipid carriers of artemether-protoporphyrin IX-transferrin combination for therapy of malaria. International journal of pharmaceutics. 2021 Aug; 605(?):120813. doi: 10.1016/j.ijpharm.2021.120813. [PMID: 34144137]
  • Tayfun Karatas, Sukru Onalan, Serkan Yildirim. Effects of prolonged fasting on levels of metabolites, oxidative stress, immune-related gene expression, histopathology, and DNA damage in the liver and muscle tissues of rainbow trout (Oncorhynchus mykiss). Fish physiology and biochemistry. 2021 Aug; 47(4):1119-1132. doi: 10.1007/s10695-021-00949-2. [PMID: 34057672]
  • Elena Alvarez-Salas, Aldo González, Maria Isabel Amaya, Patricia de Gortari. Accumbal TRH is downstream of the effects of isolation stress on hedonic food intake in rats. Nutritional neuroscience. 2021 Jul; 24(7):554-563. doi: 10.1080/1028415x.2019.1657658. [PMID: 31438781]
  • Wei Xiao, Yazhen Wang, Huilin Zhang, Yuwei Liu, Rou Xie, Xueqin He, Yang Zhou, Luqing Liang, Huile Gao. The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood-brain barrier and attenuates their targeting ability to brain tumor. Biomaterials. 2021 07; 274(?):120888. doi: 10.1016/j.biomaterials.2021.120888. [PMID: 34029915]
  • Yoshimitsu Ouchi, Miko Yamato, Vishwajit S Chowdhury, Takashi Bungo. Adenosine 5'-monophosphate induces hypothermia and alters gene expressions in the brain and liver of chicks. Brain research bulletin. 2021 07; 172(?):14-21. doi: 10.1016/j.brainresbull.2021.04.008. [PMID: 33862124]
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