Herniarin (BioDeep_00000000258)

Main id: BioDeep_00000000248

Secondary id: BioDeep_00000406716, BioDeep_00000863311

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


7-Methoxycoumarin, suitable for fluorescence, >=98.0\\% (TLC)

化学式: C10H8O3 (176.0473)
中文名称: 脱肠草内酯, 脱肠草素, 7-甲氧基香豆素, 甲氧基香豆素
谱图信息: 最多检出来源 Macaca mulatta(otcml) 22.93%

分子结构信息

SMILES: c1c(cc2c(c1)ccc(=O)o2)OC
InChI: InChI=1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3

描述信息

Herniarin, also known as 7-methoxycoumarin or ayapanin, belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Herniarin is a sweet, balsamic, and tonka tasting compound. Herniarin has been detected, but not quantified, in several different foods, such as barley, tarragons, roman camomiles, fruits, and wild celeries. This could make herniarin a potential biomarker for the consumption of these foods.
Herniarin is a member of the class of coumarins that is coumarin substituted by a methoxy group at position 7. It has a role as a fluorochrome.
7-Methoxycoumarin is a natural product found in Haplopappus multifolius, Herniaria hirsuta, and other organisms with data available.
See also: Chamomile (part of); Glycyrrhiza Glabra (part of).
Present in Prunus mahaleb (mahaleb cherry). Herniarin is found in many foods, some of which are caraway, wild celery, barley, and fruits.
A member of the class of coumarins that is coumarin substituted by a methoxy group at position 7.
Herniarin is a natural coumarin occurs in some flowering plants, with antitumor effect.
Herniarin is a natural coumarin occurs in some flowering plants, with antitumor effect.

同义名列表

52 个代谢物同义名

7-Methoxycoumarin, suitable for fluorescence, >=98.0\\% (TLC); Herniarin, primary pharmaceutical reference standard; 7-METHOXYCOUMARIN (CONSTITUENT OF CHAMOMILE) [DSC]; 7-Methoxycoumarin 100 microg/mL in Acetonitrile; 7-METHOXYCOUMARIN (CONSTITUENT OF CHAMOMILE); 5-18-01-00387 (Beilstein Handbook Reference); 7-Methoxycoumarin;Methyl umbelliferyl ether; 7-Methyl ether derivative of Umbelliferone; 7-Methoxycoumarin, analytical standard; 7-Methoxy-2H-1-benzopyran-2-one, 9CI; 2H-1-BENZOPYRAN-2-ONE, 7-METHOXY-; 7-Methoxy-2H-1-benzopyran-2-one; 7-(methyloxy)-2H-chromen-2-one; 7-methoxy-1-benzopyran-2-one; 7-Methoxy-2H-chromen-2-one #; Umbelliferone, methyl ether; Coumarin, 7-methoxy- (8CI); 7-Methoxy-2H-chromen-2-one; Umbelliferone methyl ether; Methyl umbelliferyl ether; 7-Methoxycoumarin, >=98\\%; 7-methoxy-chromen-2-one; 7-methoxychromen-2-one; Coumarin, 7-methoxy-; METHOXYCOURMARIN, 7-; METHOXYCOUMARIN, 7-; Methylumbelliferone; 7-METHOXYCOURMARIN; 7-Methoxy Coumarin; 7-methoxy-coumarin; 7-Methoxycoumarin; Spectrum4_001558; Spectrum3_000263; Spectrum2_000398; Spectrum5_000156; UNII-DGK72G008A; Herniarin (6CI); DivK1c_006418; Herniarin,(S); MEGxp0_000150; ACon1_002037; KBio1_001362; KBio2_003440; KBio2_006008; KBio3_001206; KBio2_000872; Herniarine; DGK72G008A; herniarin; Ayapanin; 7-Methoxycoumarin; Herniarin



数据库引用编号

25 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

67 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ALB, BCL2, CASP3, CASP8, CCDC88A, CYP2E1, FST, HPGDS, IFNGR2, NR1D1, NR1I3, TYR
Peripheral membrane protein 3 ACHE, CCDC88A, CYP2E1
Endoplasmic reticulum membrane 4 BCL2, CYP2E1, IFNGR2, SLN
Mitochondrion membrane 1 MAOA
Nucleus 10 ACHE, ALB, BCL2, CASP3, CASP8, FST, MMP2, NR1D1, NR1I2, NR1I3
cytosol 9 ALB, BCL2, CASP3, CASP8, CCDC88A, GPT, HPGDS, MAOA, NR1I3
dendrite 1 NR1D1
nuclear body 2 NR1D1, NR1I2
centrosome 2 ALB, CCDC88A
nucleoplasm 6 CASP3, CASP8, HPGDS, NR1D1, NR1I2, NR1I3
Cell membrane 3 ACHE, CCDC88A, IFNGR2
Cytoplasmic side 1 MAOA
lamellipodium 2 CASP8, CCDC88A
Golgi apparatus membrane 1 IFNGR2
Synapse 1 ACHE
cell surface 1 ACHE
glutamatergic synapse 1 CASP3
Golgi apparatus 3 ACHE, ALB, CCDC88A
Golgi membrane 1 IFNGR2
mitochondrial inner membrane 1 CYP2E1
neuromuscular junction 1 ACHE
neuronal cell body 1 CASP3
Cytoplasm, cytosol 1 CCDC88A
Lysosome 1 TYR
plasma membrane 6 ACHE, BCHE, CCDC88A, IFNGR2, MMP2, PRSS27
Membrane 6 ACHE, BCL2, CCDC88A, IFNGR2, MAOA, SLN
extracellular exosome 2 ALB, GPT
endoplasmic reticulum 4 ALB, BCL2, CCDC88A, IFNGR2
extracellular space 5 ACHE, ALB, BCHE, FST, MMP2
perinuclear region of cytoplasm 2 ACHE, TYR
mitochondrion 4 BCL2, CASP8, MAOA, MMP2
protein-containing complex 3 ALB, BCL2, CASP8
intracellular membrane-bounded organelle 3 CYP2E1, HPGDS, TYR
Microsome membrane 1 CYP2E1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 IFNGR2, TYR
Secreted 3 ACHE, ALB, BCHE
extracellular region 6 ACHE, ALB, BCHE, FST, MMP2, PRSS27
Mitochondrion outer membrane 2 BCL2, MAOA
Single-pass membrane protein 3 BCL2, MAOA, SLN
mitochondrial outer membrane 3 BCL2, CASP8, MAOA
Extracellular side 1 ACHE
anchoring junction 1 ALB
transcription regulator complex 1 NR1I2
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
dendritic spine 1 NR1D1
cytoplasmic vesicle 1 CCDC88A
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
Cell projection, lamellipodium 2 CASP8, CCDC88A
Mitochondrion inner membrane 1 CYP2E1
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 NR1I3
extracellular matrix 1 MMP2
basement membrane 1 ACHE
sarcoplasmic reticulum 1 SLN
Cell projection, dendritic spine 1 NR1D1
collagen-containing extracellular matrix 1 MMP2
sarcomere 1 MMP2
ciliary basal body 2 ALB, CCDC88A
chromatin 3 NR1D1, NR1I2, NR1I3
cytoskeleton 2 CASP8, NR1I3
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 CCDC88A
Cytoplasm, cytoskeleton, cilium basal body 1 CCDC88A
centriole 2 ALB, CCDC88A
spindle pole 1 ALB
blood microparticle 2 ALB, BCHE
Lipid-anchor, GPI-anchor 1 ACHE
Cytoplasmic vesicle membrane 1 IFNGR2
Cell projection, dendrite 1 NR1D1
Melanosome 1 TYR
cell body 1 CASP8
side of membrane 1 ACHE
myelin sheath 1 BCL2
intermediate filament cytoskeleton 1 NR1I2
endoplasmic reticulum lumen 2 ALB, BCHE
platelet alpha granule lumen 1 ALB
[Isoform 1]: Secreted, extracellular space, extracellular matrix 1 MMP2
Sarcoplasmic reticulum membrane 1 SLN
Single-pass type IV membrane protein 1 MAOA
nuclear envelope lumen 1 BCHE
synaptic cleft 1 ACHE
CD95 death-inducing signaling complex 1 CASP8
death-inducing signaling complex 2 CASP3, CASP8
ripoptosome 1 CASP8
BAD-BCL-2 complex 1 BCL2
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
COPI-coated Golgi to ER transport vesicle 1 CCDC88A


文献列表

  • Arman Mokaram Doust Delkhah, Ehsan Karimi, Shirin Farivar. Herniarin-loaded solid lipid nanoparticles: promising molecular mechanism and therapeutic potential against pancreatic cancer line. Molecular biology reports. 2023 Jun; ?(?):. doi: 10.1007/s11033-023-08560-9. [PMID: 37326747]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Sandra Liliana Porras-Dávila, Alejandro Zamilpa, Enrique Jiménez-Ferrer, Antonio Jiménez-Aparicio, Mayra Alejandra Santillán-Urquiza, Fernanda Díaz-Patricio, Maribel Herrera-Ruiz. Anti-inflammatory and Neuroprotective effects of standardized fractions in herniarin and daphnoretin from Distictis buccinatoria. Chemistry & biodiversity. 2023 Mar; ?(?):e202200969. doi: 10.1002/cbdv.202200969. [PMID: 36973180]
  • Elham Al Fares, Tamar Sanikidze, Sophio Kalmakhelidze, David Topuria, Luigi Mansi, Sean Kitson, Mikaeil Molazadeh. The Alleviating Effect of Herniarin Against Ionizing Radiation-Induced Genotoxicity and Cytotoxicity in Human Peripheral Blood Lymphocytes. Current radiopharmaceuticals. 2022; 15(2):141-147. doi: 10.2174/1874471014666211012104808. [PMID: 34636317]
  • Samira Asgharzade, Mohammad Bagher Khorrami, Fatemeh Forouzanfar. Neuroprotective effect of herniarin following transient focal cerebral ischemia in rats. Metabolic brain disease. 2021 12; 36(8):2505-2510. doi: 10.1007/s11011-021-00841-1. [PMID: 34519909]
  • Jingxuan Ke, Jinxi Cheng, Qingying Luo, Hejun Wu, Guanghui Shen, Zhiqing Zhang. Identification of two bitter components in Zanthoxylum bungeanum Maxim. and exploration of their bitter taste mechanism through receptor hTAS2R14. Food chemistry. 2021 Feb; 338(?):127816. doi: 10.1016/j.foodchem.2020.127816. [PMID: 32818866]
  • Stéphane Zingue, Harquin Simplice Foyet, Sefirin Djiogue, Yannick Ezo'o Ezo'o, Hervé Hervé Ngatanko Abaïssou, Pafroumi Fachagbo, Dieudonné Njamen. Effects of Ficus umbellata (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats. Behavioural neurology. 2018; 2018(?):5751864. doi: 10.1155/2018/5751864. [PMID: 30363978]
  • Rita de Cássia L Lima, Simone M Gramsbergen, Johannes Van Staden, Anna K Jäger, Kenneth T Kongstad, Dan Staerk. Advancing HPLC-PDA-HRMS-SPE-NMR Analysis of Coumarins in Coleonema album by Use of Orthogonal Reversed-Phase C18 and Pentafluorophenyl Separations. Journal of natural products. 2017 04; 80(4):1020-1027. doi: 10.1021/acs.jnatprod.6b01020. [PMID: 28248501]
  • Lamia Heikal, Anna Starr, Gary P Martin, Manasi Nandi, Lea Ann Dailey. In vivo pharmacological activity and biodistribution of S-nitrosophytochelatins after intravenous and intranasal administration in mice. Nitric oxide : biology and chemistry. 2016 09; 59(?):1-9. doi: 10.1016/j.niox.2016.06.006. [PMID: 27350118]
  • Hai-Ning Lv, Shu Wang, Ke-Wu Zeng, Jun Li, Xiao-Yu Guo, Daneel Ferreira, Jordan K Zjawiony, Peng-Fei Tu, Yong Jiang. Anti-inflammatory coumarin and benzocoumarin derivatives from Murraya alata. Journal of natural products. 2015 Feb; 78(2):279-85. doi: 10.1021/np500861u. [PMID: 25621853]
  • R Bertin, Z Chen, M Martínez-Vázquez, A García-Argaéz, G Froldi. Vasodilation and radical-scavenging activity of imperatorin and selected coumarinic and flavonoid compounds from genus Casimiroa. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2014 Apr; 21(5):586-94. doi: 10.1016/j.phymed.2013.10.030. [PMID: 24309287]
  • Michal Kielbus, Krystyna Skalicka-Wozniak, Aneta Grabarska, Witold Jeleniewicz, Magdalena Dmoszynska-Graniczka, Andrew Marston, Krzysztof Polberg, Piotr Gawda, Janusz Klatka, Andrzej Stepulak. 7-substituted coumarins inhibit proliferation and migration of laryngeal cancer cells in vitro. Anticancer research. 2013 Oct; 33(10):4347-56. doi: . [PMID: 24123002]
  • M Abu Mraheil, A Heisig, P Heisig. An improved assay for the detection of alterations in bacterial DNA supercoiling in vivo. Die Pharmazie. 2013 Jul; 68(7):541-8. doi: ". [PMID: 23923635]
  • Enos Tangke Arung, Harlinda Kuspradini, Irawan Wijaya Kusuma, Kuniyoshi Shimizu, Ryuichiro Kondo. Validation of Eupatorium triplinerve Vahl leaves, a skin care herb from East Kalimantan, using a melanin biosynthesis assay. Journal of acupuncture and meridian studies. 2012 Apr; 5(2):87-92. doi: 10.1016/j.jams.2012.01.003. [PMID: 22483187]
  • Min Hong, Hong-Yu Ma, Xiang-Rui Wu, Yong-Qing Hua, Quan Zhu, Hong-Wei Fan. A method of hepatocyte extraction conjugated with HPLC is established for screening potential active components in Chinese medicines--probing Herba Artemisiae Scopariae as an exemplifying approach. Molecules (Basel, Switzerland). 2012 Feb; 17(2):1468-82. doi: 10.3390/molecules17021468. [PMID: 22310168]
  • Sadaf Naeem, Peter Hylands, David Barlow. Construction of an Indonesian herbal constituents database and its use in Random Forest modelling in a search for inhibitors of aldose reductase. Bioorganic & medicinal chemistry. 2012 Feb; 20(3):1251-8. doi: 10.1016/j.bmc.2011.12.033. [PMID: 22261024]
  • Agnes M Móricz, Szabolcs Szarka, Péter G Ott, Eva B Héthelyi, Eva Szoke, Erno Tyihák. Separation and identification of antibacterial chamomile components using OPLC, bioautography and GC-MS. Medicinal chemistry (Shariqah (United Arab Emirates)). 2012 Jan; 8(1):85-94. doi: 10.2174/157340612799278487. [PMID: 22420556]
  • Michael D Preston, Kurt A Smemo, James W McLaughlin, Nathan Basiliko. Peatland microbial communities and decomposition processes in the james bay lowlands, Canada. Frontiers in microbiology. 2012; 3(?):70. doi: 10.3389/fmicb.2012.00070. [PMID: 22393328]
  • Jerusa A Q A Faria, Pedro A B Reis, Marco T B Reis, Gustavo L Rosado, Guilherme L Pinheiro, Giselle C Mendes, Elizabeth P B Fontes. The NAC domain-containing protein, GmNAC6, is a downstream component of the ER stress- and osmotic stress-induced NRP-mediated cell-death signaling pathway. BMC plant biology. 2011 Sep; 11(?):129. doi: 10.1186/1471-2229-11-129. [PMID: 21943253]
  • Wafaa A Tawfik, Mona M Abdel-Mohsen, Hany M Radwan, Amira A Habib, M A Yeramian. Phytochemical and biological investigations of Atriplex semibacata R .BR. growing in Egypt. African journal of traditional, complementary, and alternative medicines : AJTCAM. 2011; 8(4):435-43. doi: 10.4314/ajtcam.v8i4.15. [PMID: 22654223]
  • Ompal Singh, Zakia Khanam, Neelam Misra, Manoj Kumar Srivastava. Chamomile (Matricaria chamomilla L.): An overview. Pharmacognosy reviews. 2011 Jan; 5(9):82-95. doi: 10.4103/0973-7847.79103. [PMID: 22096322]
  • Joanne Canonne, Daniel Marino, Laurent D Noël, Ignacio Arechaga, Carole Pichereaux, Michel Rossignol, Dominique Roby, Susana Rivas. Detection and functional characterization of a 215 amino acid N-terminal extension in the Xanthomonas type III effector XopD. PloS one. 2010 Dec; 5(12):e15773. doi: 10.1371/journal.pone.0015773. [PMID: 21203472]
  • Yunbao Liu, Muraleedharan G Nair. An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. Journal of natural products. 2010 Jul; 73(7):1193-5. doi: 10.1021/np1000945. [PMID: 20565070]
  • Satoru Tamura, Toshiaki Fujitani, Masafumi Kaneko, Nobutoshi Murakami. Prenylcoumarin with Rev-export inhibitory activity from Cnidii Monnieris Fructus. Bioorganic & medicinal chemistry letters. 2010 Jun; 20(12):3717-20. doi: 10.1016/j.bmcl.2010.04.081. [PMID: 20493693]
  • Evy Paulsen, Aksel Otkjaer, Klaus E Andersen. The coumarin herniarin as a sensitizer in German chamomile [Chamomilla recutita (L.) Rauschert, Compositae]. Contact dermatitis. 2010 Jun; 62(6):338-42. doi: 10.1111/j.1600-0536.2010.01730.x. [PMID: 20557339]
  • Nga T Lao, Alan P Maloney, John F Atkins, Tony A Kavanagh. Versatile dual reporter gene systems for investigating stop codon readthrough in plants. PloS one. 2009 Oct; 4(10):e7354. doi: 10.1371/journal.pone.0007354. [PMID: 19816579]
  • Rosa Martha Pérez Gutiérrez, Rosario Vargas Solis, Efren Garcia Baez, Yoha Gallardo Navarro. Hypoglycemic activity of constituents from Astianthus viminalis in normal and streptozotocin-induced diabetic mice. Journal of natural medicines. 2009 Oct; 63(4):393-401. doi: 10.1007/s11418-009-0343-7. [PMID: 19484331]
  • Timothy J Haig, Terry J Haig, Alexa N Seal, James E Pratley, Min An, Hanwen Wu. Lavender as a source of novel plant compounds for the development of a natural herbicide. Journal of chemical ecology. 2009 Sep; 35(9):1129-36. doi: 10.1007/s10886-009-9689-2. [PMID: 19787403]
  • Tamsyn S A Thring, Pauline Hili, Declan P Naughton. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC complementary and alternative medicine. 2009 Aug; 9(?):27. doi: 10.1186/1472-6882-9-27. [PMID: 19653897]
  • Miroslav Repcák, Benadik Smajda, Jozef Kovácik, Adriana Eliasová. Circadian rhythm of Z- and E-2-beta-D: -glucopyranosyloxy-4-methoxy cinnamic acids and herniarin in leaves of Matricaria chamomilla. Plant cell reports. 2009 Jul; 28(7):1137-43. doi: 10.1007/s00299-009-0708-0. [PMID: 19430793]
  • Prince Firdoos Iqbal, Abdul Roouf Bhat, Amir Azam. Antiamoebic coumarins from the root bark of Adina cordifolia and their new thiosemicarbazone derivatives. European journal of medicinal chemistry. 2009 May; 44(5):2252-9. doi: 10.1016/j.ejmech.2008.06.003. [PMID: 18675491]
  • Jozef Kovácik, Jirí Grúz, Martin Backor, Miroslav Strnad, Miroslav Repcák. Salicylic acid-induced changes to growth and phenolic metabolism in Matricaria chamomilla plants. Plant cell reports. 2009 Jan; 28(1):135-43. doi: 10.1007/s00299-008-0627-5. [PMID: 18972114]
  • Xiao-jie Tan, Qing Li, Xiao-hui Chen, Zhi-wei Wang, Zheng-yuan Shi, Kai-shun Bi, Ying Jia. Simultaneous determination of 13 bioactive compounds in Herba Artemisiae Scopariae (Yin Chen) from different harvest seasons by HPLC-DAD. Journal of pharmaceutical and biomedical analysis. 2008 Aug; 47(4-5):847-53. doi: 10.1016/j.jpba.2008.04.010. [PMID: 18502075]
  • Mario Figueroa, Isabel Rivero-Cruz, Blanca Rivero-Cruz, Robert Bye, Andrés Navarrete, Rachel Mata. Constituents, biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida. Journal of ethnopharmacology. 2007 Aug; 113(1):125-31. doi: 10.1016/j.jep.2007.05.015. [PMID: 17582715]
  • Victor Kuete, Robert Metuno, Bathélémy Ngameni, Armelle Mbaveng Tsafack, François Ngandeu, Ghislain Wabo Fotso, Merhatibeb Bezabih, François-Xavier Etoa, Bonaventure Tchaleu Ngadjui, Berhanu M Abegaz, Véronique Penlap Beng. Antimicrobial activity of the methanolic extracts and compounds from Treculia obovoidea (Moraceae). Journal of ethnopharmacology. 2007 Jul; 112(3):531-6. doi: 10.1016/j.jep.2007.04.010. [PMID: 17532157]
  • Fabiana N Fonseca, Marina F M Tavares, Csaba Horváth. Capillary electrochromatography of selected phenolic compounds of Chamomilla recutita. Journal of chromatography. A. 2007 Jun; 1154(1-2):390-9. doi: 10.1016/j.chroma.2007.03.106. [PMID: 17459397]
  • Ian Cummins, Marie Landrum, Patrick G Steel, Robert Edwards. Structure activity studies with xenobiotic substrates using carboxylesterases isolated from Arabidopsis thaliana. Phytochemistry. 2007 Mar; 68(6):811-8. doi: 10.1016/j.phytochem.2006.12.014. [PMID: 17270225]
  • Chao-Mei Ma, Linda Winsor, Mohsen Daneshtalab. Quantification of spiroether isomers and herniarin of different parts of Matricaria matricarioides and flowers of Chamaemelum nobile. Phytochemical analysis : PCA. 2007 Jan; 18(1):42-9. doi: 10.1002/pca.950. [PMID: 17260697]
  • Wei-Xia Song, Teng-Fei Ji, Yi-Kang Si, Ya-Lun Su. [Studies on chemical constituents in herb from Artemisia rupestris]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Nov; 31(21):1790-2. doi: . [PMID: 17260794]
  • Muhammad Iqbal Choudhary, Saima Jalil, Muddasir Israr. Inhibition of respiratory burst in human neutrophils and lipoxygenase enzyme by compounds from Haloxylon griffithii. Phytotherapy research : PTR. 2006 Oct; 20(10):840-3. doi: 10.1002/ptr.1914. [PMID: 16835879]
  • Lai-Hao Wang, Si-Yun Jiang. Simultaneous determination of urinary metabolites of methoxypsoralens in human and Umbelliferae medicines by high-performance liquid chromatography. Journal of chromatographic science. 2006 Sep; 44(8):473-8. doi: 10.1093/chromsci/44.8.473. [PMID: 16959122]
  • Mian Zhang, Chao-Feng Zhang, Zheng-Tao Wang. The chemical constituents of Ligularia pleurocaulis. Yao xue xue bao = Acta pharmaceutica Sinica. 2005 Jun; 40(6):529-32. doi: ". [PMID: 16144318]
  • Jaime A Yáñez, Xiao Wei Teng, Kathryn A Roupe, Neal M Davies. Stereospecific high-performance liquid chromatographic analysis of hesperetin in biological matrices. Journal of pharmaceutical and biomedical analysis. 2005 Mar; 37(3):591-5. doi: 10.1016/j.jpba.2004.10.028. [PMID: 15740921]
  • Shu-Guo Hu, Li Li, Xi-Wen He. Solid-phase extraction of esculetin from the ash bark of Chinese traditional medicine by using molecularly imprinted polymers. Journal of chromatography. A. 2005 Jan; 1062(1):31-7. doi: 10.1016/j.chroma.2004.11.036. [PMID: 15679140]
  • Conchita Alonso, Ricardo Pérez, Pedro M Nieto, Julio Delgado. Gender dimorphism and altitudinal variation of secondary compounds in leaves of the gynodioecious shrub Daphne laureola. Journal of chemical ecology. 2005 Jan; 31(1):139-50. doi: 10.1007/s10886-005-0980-6. [PMID: 15839486]
  • Jun Watanabe, Hiroshi Shinmoto, Tojiro Tsushida. Coumarin and flavone derivatives from estragon and thyme as inhibitors of chemical mediator release from RBL-2H3 Cells. Bioscience, biotechnology, and biochemistry. 2005 Jan; 69(1):1-6. doi: 10.1271/bbb.69.1. [PMID: 15665459]
  • Henrik Toft Simonsen, Anne Adsersen, Paul Bremner, Michael Heinrich, Ulla Wagner Smitt, Jerzy W Jaroszewski. Antifungal constituents of Melicope borbonica. Phytotherapy research : PTR. 2004 Jul; 18(7):542-5. doi: 10.1002/ptr.1482. [PMID: 15305313]
  • Adriana Eliasová, Miroslav Repcák, Andrea Pastírová. Quantitative changes of secondary metabolites of Matricaria chamomilla by abiotic stress. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2004 Jul; 59(7-8):543-8. doi: 10.1515/znc-2004-7-817. [PMID: 15813377]
  • Anna Oliva, Kumudini M Meepagala, David E Wedge, Dewayne Harries, Amber L Hale, Giovanni Aliotta, Stephen O Duke. Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid. Journal of agricultural and food chemistry. 2003 Feb; 51(4):890-6. doi: 10.1021/jf0259361. [PMID: 12568545]
  • Rita Aquino, Armando Cáceres, Silvana Morelli, Luca Rastrelli. An extract of Tagetes lucida and its phenolic constituents as antioxidants. Journal of natural products. 2002 Dec; 65(12):1773-6. doi: 10.1021/np020018i. [PMID: 12502312]
  • Claudia Osterhage, Gabriele M König, Peter G Jones, Anthony D Wright. 5-hydroxyramulosin, a new natural product produced by Phoma tropica, a marine-derived fungus isolated from the alga Fucus spiralis. Planta medica. 2002 Nov; 68(11):1052-4. doi: 10.1055/s-2002-35670. [PMID: 12451504]
  • A M Silván, M J Abad, P Bermejo, M Sollhuber, A Villar. Antiinflammatory activity of coumarins from Santolina oblongifolia. Journal of natural products. 1996 Dec; 59(12):1183-5. doi: 10.1021/np960422f. [PMID: 8988605]
  • K Tschiersch, J Hölzl. [Absorption and excretion of apigenin, apigenin-7-glycoside and herniarin after oral administration of extracts of Matricaria recutita (L.) (syn. Chamomilla recutita (L.) Rauschert)]. Die Pharmazie. 1993 Jul; 48(7):554-5. doi: NULL. [PMID: 8415854]
  • C Salerno, J E Churchich, P M Fasella. Fluorescence polarization studies on the binding between glutamate dehydrogenase and cytoplasmic aspartate aminotransferase. The Italian journal of biochemistry. 1975 Nov; 24(6):351-9. doi: NULL. [PMID: 3487]
  • A C Buck. Disorders of micturition in bacterial prostatitis. Proceedings of the Royal Society of Medicine. 1975 Aug; 68(8):508-11. doi: NULL. [PMID: 681]
  • S R Indahl, R R Scheline. The metabolism of umbelliferone and herniarin in rats and by the rat intestinal microflora. Xenobiotica; the fate of foreign compounds in biological systems. 1971 Jan; 1(1):13-24. doi: 10.3109/00498257109044375. [PMID: 5163172]
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