Benzo[e]pyrene (BioDeep_00000009898)
Secondary id: BioDeep_00001873628
human metabolite blood metabolite
代谢物信息卡片
pentacyclo[10.6.2.0^{2,7}.0^{8,20}.0^{15,19}]icosa-1(18),2,4,6,8,10,12(20),13,15(19),16-decaene
化学式: C20H12 (252.0939)
中文名称: 苯并[e]芘
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C1=CC=CC3=C1C1=C(C=CC=C21)C=C3
InChI: InChI=1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:34567
- KEGG: C14435
- PubChem: 9128
- HMDB: HMDB0249007
- Metlin: METLIN70058
- ChEMBL: CHEMBL1371125
- Wikipedia: Benzo(e)pyrene
- chemspider: 8774
- CAS: 73467-76-2
- CAS: 192-97-2
- PMhub: MS000023719
- PubChem: 17395435
- NIKKAJI: J2.971H
- LOTUS: LTS0046164
- wikidata: Q2645019
- KNApSAcK: 34567
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 4097 - Nicotiana tabacum: 10.1016/0378-8741(88)90069-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- M S Volkov, N A Bolotina, V A Evteev, V A Koblyakov. Ah-receptor-independent stimulation of hepatoma 27 culture cell proliferation by polycyclic aromatic hydrocarbons.
Biochemistry. Biokhimiia.
2012 Feb; 77(2):201-7. doi:
10.1134/s0006297912020125. [PMID: 22348481] - Han-Bin Huang, Ching-Huang Lai, Guan-Wen Chen, Yong-Yang Lin, Jouni J K Jaakkola, Saou-Hsing Liou, Shu-Li Wang. Traffic-related air pollution and DNA damage: a longitudinal study in Taiwanese traffic conductors.
PloS one.
2012; 7(5):e37412. doi:
10.1371/journal.pone.0037412. [PMID: 22629390] - Lawrence R Curtis, Claudia B Garzon, Mary Arkoosh, Tracy Collier, Mark S Myers, Jon Buzitis, Mark E Hahn. Reduced cytochrome P4501A activity and recovery from oxidative stress during subchronic benzo[a]pyrene and benzo[e]pyrene treatment of rainbow trout.
Toxicology and applied pharmacology.
2011 Jul; 254(1):1-7. doi:
10.1016/j.taap.2011.04.015. [PMID: 21550360] - Normand Podechard, Olivier Fardel, Michel Corolleur, Marc Bernard, Valérie Lecureur. Inhibition of human mesenchymal stem cell-derived adipogenesis by the environmental contaminant benzo(a)pyrene.
Toxicology in vitro : an international journal published in association with BIBRA.
2009 Sep; 23(6):1139-44. doi:
10.1016/j.tiv.2009.05.011. [PMID: 19486938] - Giorgia Purcaro, Sabrina Moret, Lanfranco S Conte. Rapid SPE-HPLC determination of the 16 European priority polycyclic aromatic hydrocarbons in olive oils.
Journal of separation science.
2008 Dec; 31(22):3936-44. doi:
10.1002/jssc.200800392. [PMID: 18985665] - Rafael Rodríguez-Acuña, María del Carmen Pérez-Camino, Arturo Cert, Wenceslao Moreda. Polycyclic aromatic hydrocarbons in spanish olive oils: relationship between benzo(a)pyrene and total polycyclic aromatic hydrocarbon content.
Journal of agricultural and food chemistry.
2008 Nov; 56(21):10428-32. doi:
10.1021/jf8016699. [PMID: 18831590] - Diógenes Herreño Sáenz, Qingsu Xia, Peter P Fu. UVA photoirradiation of methylated benzo[a]pyrene and benzo[e]pyrene leading to induction of lipid peroxidation.
International journal of environmental research and public health.
2007 Jun; 4(2):153-7. doi:
10.3390/ijerph2007040010. [PMID: 17617679] - Yi Wan, Xiaohui Jin, Jianying Hu, Fen Jin. Trophic dilution of polycyclic aromatic hydrocarbons (PAHs) in a marine food web from Bohai Bay, north China.
Environmental science & technology.
2007 May; 41(9):3109-14. doi:
10.1021/es062594x. [PMID: 17539512] - M Fontcuberta, J F Arqués, M Martínez, A Suárez, J R Villalbí, F Centrich, E Serrahima, J Duran, C Casas. Polycyclic aromatic hydrocarbons in food samples collected in Barcelona, Spain.
Journal of food protection.
2006 Aug; 69(8):2024-8. doi:
10.4315/0362-028x-69.8.2024. [PMID: 16924937] - Daniëlle M J Curfs, Ad M Knaapen, Daniëlle M F A Pachen, Marion J J Gijbels, Esther Lutgens, Marjan L F Smook, Mark M Kockx, Mat J A P Daemen, Frederik J van Schooten. Polycyclic aromatic hydrocarbons induce an inflammatory atherosclerotic plaque phenotype irrespective of their DNA binding properties.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2005 Aug; 19(10):1290-2. doi:
10.1096/fj.04-2269fje. [PMID: 15939734] - S Faiderbe, J L Chagnaud, M Geffard. Identification and characterization of a specific autoantiphosphatidylinositol immune response during the time course of benzo(a)pyrene-induced malignant tumors in female Sprague-Dawley rats.
Cancer research.
1992 May; 52(10):2862-5. doi:
. [PMID: 1581900] - N Hahon, J A Booth. Coinhibition of viral interferon induction by benzo[a]pyrene and chrysotile asbestos.
Environmental research.
1986 Jun; 40(1):103-9. doi:
10.1016/s0013-9351(86)80086-x. [PMID: 2423322] - N W Revis, R Bull, D Laurie, C A Schiller. The effectiveness of chemical carcinogens to induce atherosclerosis in the white Carneau pigeon.
Toxicology.
1984 Sep; 32(3):215-27. doi:
10.1016/0300-483x(84)90075-1. [PMID: 6089378] - H Coulomb, Z Gu, S Audu, I Chouroulinkov. The uptake and release of benzo[a]pyrene and benzo[e]pyrene in vitro by Syrian hamster embryo cells as a function of serum concentration.
Carcinogenesis.
1981; 2(6):523-7. doi:
10.1093/carcin/2.6.523. [PMID: 6268328] - J Lautier, J L Chanal, J Guibert, J G Lagarrigue. Study of clofibric acid distribution, metabolism and model, in crab Pachygrapsus marmoratus (Decapoda, Brachyura).
Comparative biochemistry and physiology. C: Comparative pharmacology.
1977; 58(2C):173-5. doi:
10.1016/0306-4492(77)90100-9. [PMID: 23930] - G K Hanasono, M G Côté, G L Plaa. Potentiation of carbon tetrachloride-induced hepatotoxicity in alloxan- or strepto- zotocin-diabetic rats.
The Journal of pharmacology and experimental therapeutics.
1975 Mar; 192(3):592-604. doi:
. [PMID: 164533]
