1,2-Dimethylnaphthalene (BioDeep_00000009831)

 

Secondary id: BioDeep_00001874249

human metabolite blood metabolite natural product


代谢物信息卡片


1,2-DIMETHYLNAPHTHALENE

化学式: C12H12 (156.0939)
中文名称: 1,2-二甲基萘
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: CC1=C(C2=CC=CC=C2C=C1)C
InChI: InChI=1S/C12H12/c1-9-7-8-11-5-3-4-6-12(11)10(9)2/h3-8H,1-2H3

描述信息

同义名列表

4 个代谢物同义名

1,2-DIMETHYLNAPHTHALENE; 1,2-DMN; 1,2-Dimethylnaphthalene; 1,2-Dimethylnaphthalene



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 CYP2A6, CYP2E1, GPX2, HPGDS, PRDX6, PTGS2, RAC1, RPL15, RPS20
Peripheral membrane protein 3 CYP2E1, PTGS2, SORD
Endoplasmic reticulum membrane 4 CYP2A6, CYP2E1, PTGS2, RAC1
Mitochondrion membrane 1 SORD
Nucleus 4 GPX4, PRDX6, RAC1, RPL15
cytosol 8 GPX2, GPX4, HPGDS, PRDX6, RAC1, RPL15, RPS20, SORD
dendrite 1 RAC1
mitochondrial membrane 1 SORD
trans-Golgi network 1 RAC1
nucleoplasm 2 HPGDS, RPS20
Cell membrane 1 RAC1
Lipid-anchor 1 RAC1
Cytoplasmic side 1 RAC1
lamellipodium 1 RAC1
ruffle membrane 1 RAC1
Synapse 3 RAC1, RPL15, RPS20
cell cortex 1 RAC1
glutamatergic synapse 1 RAC1
mitochondrial inner membrane 1 CYP2E1
postsynapse 1 RAC1
sarcolemma 1 SYNM
Cytoplasm, cytosol 1 GPX2
Lysosome 1 PRDX6
plasma membrane 1 RAC1
Membrane 5 CYP2A6, PRDX6, RAC1, RPS20, SORD
caveola 1 PTGS2
extracellular exosome 5 GPX4, PRDX6, RAC1, RPS20, SORD
endoplasmic reticulum 1 PTGS2
extracellular space 4 CXCL8, IL10, PRDX6, SORD
perinuclear region of cytoplasm 1 PRDX6
adherens junction 1 SYNM
mitochondrion 2 GPX4, PRDX6
protein-containing complex 2 GPX4, PTGS2
intracellular membrane-bounded organelle 3 CYP2A6, CYP2E1, HPGDS
Microsome membrane 2 CYP2E1, PTGS2
Secreted 3 CXCL8, IL10, RAC1
extracellular region 4 CXCL8, IL10, PRDX6, RAC1
motile cilium 1 SORD
dendritic spine 1 RAC1
cytoplasmic vesicle 1 RAC1
Cell projection, lamellipodium 1 RAC1
Mitochondrion inner membrane 1 CYP2E1
focal adhesion 1 RAC1
intermediate filament 1 SYNM
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
mitotic spindle 1 GPX2
cytoskeleton 1 RAC1
cytoplasmic ribonucleoprotein granule 1 RAC1
Cell projection, cilium, flagellum 1 SORD
intercellular bridge 1 GPX2
nuclear envelope 1 GPX4
Recycling endosome membrane 1 RAC1
Cell projection, dendrite 1 RAC1
Melanosome 1 RAC1
intermediate filament cytoskeleton 1 SYNM
secretory granule membrane 1 RAC1
endoplasmic reticulum lumen 1 PTGS2
azurophil granule lumen 1 PRDX6
A band 1 RPL15
ribonucleoprotein complex 1 RPS20
costamere 1 SYNM
neurofilament cytoskeleton 1 SYNM
cytoplasmic microtubule 1 CYP2A6
ficolin-1-rich granule membrane 1 RAC1
cytosolic ribosome 2 RPL15, RPS20
ribosome 1 RPL15
NADPH oxidase complex 1 RAC1
cytosolic large ribosomal subunit 1 RPL15
[Isoform Mitochondrial]: Mitochondrion 1 GPX4
cytosolic small ribosomal subunit 1 RPS20
[Isoform Cytoplasmic]: Cytoplasm 1 GPX4
small ribosomal subunit 1 RPS20
ribosomal subunit 1 RPL15


文献列表

  • F Muhammad, N A Monteiro-Riviere, R E Baynes, J E Riviere. Effect of in vivo jet fuel exposure on subsequent in vitro dermal absorption of individual aromatic and aliphatic hydrocarbon fuel constituents. Journal of toxicology and environmental health. Part A. 2005 May; 68(9):719-37. doi: 10.1080/15287390590925456. [PMID: 16020199]
  • F Muhammad, N A Monteiro-Riviere, J E Riviere. Comparative in vivo toxicity of topical JP-8 jet fuel and its individual hydrocarbon components: identification of tridecane and tetradecane as key constituents responsible for dermal irritation. Toxicologic pathology. 2005; 33(2):258-66. doi: 10.1080/01926230590908222. [PMID: 15902969]
  • Changchun Yuan, Peng Nan, Suhua Shi, Yang Zhong. Chemical composition of the essential oils of two Chinese endemic Meconopsis species. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2003 May; 58(5-6):313-5. doi: 10.1515/znc-2003-5-603. [PMID: 12872920]
  • Hideyuki Yamada, Ayako Yamahara, Satsuki Yasuda, Masamiki Abe, Kazuta Oguri, Sunao Fukushima, Sachiko Ikeda-Wada. Dansyl chloride derivatization of methamphetamine: a method with advantages for screening and analysis of methamphetamine in urine. Journal of analytical toxicology. 2002 Jan; 26(1):17-22. doi: 10.1093/jat/26.1.17. [PMID: 11888012]
  • A Kilanowicz, A Sapota. Disposition and metabolism of 1,2-dimethylnaphthalene in rats. International journal of occupational medicine and environmental health. 1998; 11(4):305-17. doi: NULL. [PMID: 10028198]