Luliconazole (BioDeep_00000009462)
代谢物信息卡片
化学式: C14H9Cl2N3S2 (352.9615)
中文名称: 卢立康唑
谱图信息:
最多检出来源 Homo sapiens(not specific) 50%
分子结构信息
SMILES: C1C(SC(=C(C#N)N2C=CN=C2)S1)C3=C(C=C(C=C3)Cl)Cl
InChI: InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
描述信息
D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use > D01AC - Imidazole and triazole derivatives
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
Same as: D01980
同义名列表
2 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:34825
- KEGG: C13478
- KEGGdrug: D01980
- PubChem: 3003141
- Metlin: METLIN69580
- DrugBank: DB08933
- ChEMBL: CHEMBL2105689
- CAS: 187164-19-8
- PMhub: MS000023249
- PubChem: 586216
- NIKKAJI: J937.034J
- RefMet: Luliconazole
- KNApSAcK: 34825
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Arisha Mahmood, Vamshi Krishna Rapalli, Srividya Gorantla, Tejashree Waghule, Gautam Singhvi. Dermatokinetic assessment of luliconazole-loaded nanostructured lipid carriers (NLCs) for topical delivery: QbD-driven design, optimization, and in vitro and ex vivo evaluations.
Drug delivery and translational research.
2022 05; 12(5):1118-1135. doi:
10.1007/s13346-021-00986-7
. [PMID: 33895936] - Eranti Bhargav, Yiragamreddy Padmanabha Reddy, Kunnatur B Koteshwara. Development and Optimization of Luliconazole Nanostructured Lipid Carriers Based Gel by Quality by Design its Skin Distribution Studies, Dermatokinetic Modeling & In-Vitro and Ex-Vivo Correlation.
Current drug delivery.
2021; 18(7):1041-1053. doi:
10.2174/1567201818666201214145818
. [PMID: 33319682] - Manjot Kaur, Kanwardeep Singh, Subheet Kumar Jain. Luliconazole vesicular based gel formulations for its enhanced topical delivery.
Journal of liposome research.
2020 Dec; 30(4):388-406. doi:
10.1080/08982104.2019.1682602
. [PMID: 31631734] - Saahil Baghel, Vishnumaya S Nair, Asma Pirani, Anne Boyina Sravani, Brahmam Bhemisetty, Koteshwara Ananthamurthy, Jesil Mathew Aranjani, Shaila A Lewis. Luliconazole-loaded nanostructured lipid carriers for topical treatment of superficial Tinea infections.
Dermatologic therapy.
2020 11; 33(6):e13959. doi:
10.1111/dth.13959
. [PMID: 32618400] - Maha M Abou El-Alamin, Maha A Sultan, Mostafa A Atia, Hassan Y Aboul-Enein. Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs Using High-performance Liquid Chromatography.
Combinatorial chemistry & high throughput screening.
2020; 23(10):991-1001. doi:
10.2174/1386207323666200220114818
. [PMID: 32077818] - Keiko Wakumoto-Nakashima, Nanako Yamada, Shinichi Morino, Osamu Yamamoto. Novel in vivo observations on double acting points of luliconazole on Trichophyton rubrum: an ultrastructural study.
Medical mycology.
2015 Nov; 53(8):860-7. doi:
10.1093/mmy/myv058
. [PMID: 26316213] - T Jones, A Tavakkol. Safety and tolerability of luliconazole solution 10-percent in patients with moderate to severe distal subungual onychomycosis.
Antimicrobial agents and chemotherapy.
2013 Jun; 57(6):2684-9. doi:
10.1128/aac.02370-12
. [PMID: 23545529] - J R Koup, W J Jusko, A L Goldfarb. pH-dependent secretion of procainamide into saliva.
Journal of pharmaceutical sciences.
1975 Dec; 64(12):2008-10. doi:
10.1002/jps.2600641226
. [PMID: 1514]