Mercury chloride (BioDeep_00000009445)
代谢物信息卡片
Mercury(II) chloride
化学式: HgCl2 (271.908338)
中文名称: 氯化汞
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: Cl[Hg]Cl
InChI: /q
描述信息
D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AK - Mercurial products
D000890 - Anti-Infective Agents
D004202 - Disinfectants
Same as: D01905
同义名列表
3 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:31823
- KEGG: C13377
- KEGGdrug: D01905
- PubChem: 24085
- DrugBank: DB13765
- MeSH: Mercuric Chloride
- CAS: 7487-94-7
- PubChem: 586121
- NIKKAJI: J3.741I
分类词条
相关代谢途径
Reactome(0)
BioCyc(8)
- linamarin degradation
- linustatin bioactivation
- NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)
- superpathway NAD/NADP - NADH/NADPH interconversion (yeast)
- superpathway NAD/NADP - NADH/NADPH interconversion
- NAD/NADP-NADH/NADPH cytosolic interconversion
- podophyllotoxin glucosides metabolism
- galloylated catechin biosynthesis
PlantCyc(3)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shefalee Singh, Shikha Dwivedi, Adeel Ahmad Khan, Anamika Jain, Shraddha Dwivedi, Kamlesh Kumar Yadav, Indrani Dubey, Abha Trivedi, Sunil P Trivedi, Manoj Kumar. Oxidative stress, inflammation, and steatosis elucidate the complex dynamics of HgCl2 induced liver damage in Channa punctata.
Scientific reports.
2024 04; 14(1):9161. doi:
10.1038/s41598-024-59917-4. [PMID: 38644412] - Fazal Amin, Arwa Abdulkreem Al-Huqail, Sami Ullah, Muhammad Nauman Khan, Alevcan Kaplan, Baber Ali, Majid Iqbal, Fahmy Gad Elsaid, Sezai Ercisli, Tabarak Malik, Sami Asir Al-Robai, Amany H A Abeed. Mitigation effect of alpha-tocopherol and thermo-priming in Brassica napus L. under induced mercuric chloride stress.
BMC plant biology.
2024 Feb; 24(1):108. doi:
10.1186/s12870-024-04767-5. [PMID: 38347449] - Mahmoud M Kamal, Hanan S El-Abhar, Dalaal M Abdallah, Kawkab A Ahmed, Nour Eldin S Aly, Mostafa A Rabie. Mirabegron, dependent on β3-adrenergic receptor, alleviates mercuric chloride-induced kidney injury by reversing the impact on the inflammatory network, M1/M2 macrophages, and claudin-2.
International immunopharmacology.
2024 Jan; 126(?):111289. doi:
10.1016/j.intimp.2023.111289. [PMID: 38016347] - Chuan Ouyang, Xuan Ma, Jiali Zhao, Siqi Li, Chen Liu, Yunfeng Tang, Jian Zhou, Junhao Chen, Xiaohong Li, Wanwei Li. Oleanolic acid inhibits mercury chloride induced-liver ferroptosis by regulating ROS/iron overload.
Ecotoxicology and environmental safety.
2023 Jun; 258(?):114973. doi:
10.1016/j.ecoenv.2023.114973. [PMID: 37163906] - T Turdiyev, I Kovalchuk, Z Mukhitdinova, O Hunger, S Frolov, B Kabylbekova. Micropropagation of berry crops for creation of germplasm cryobanks.
Brazilian journal of biology = Revista brasleira de biologia.
2023; 84(?):e266975. doi:
10.1590/1519-6984.266975. [PMID: 37194800] - Jia-Hong Chu, Lan-Xin Li, Pei-Chao Gao, Xue-Wei Chen, Zhen-Yong Wang, Rui-Feng Fan. Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy.
Free radical biology & medicine.
2022 Aug; 188(?):35-44. doi:
10.1016/j.freeradbiomed.2022.06.002. [PMID: 35675856] - Z Z Gao, Y J Pan, J Ma, H L Li, X Mei, Y G Song. [Study on the difference of curative effect of conventional mercury displacement treatment on mercury in brain and kidney].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2022 Apr; 40(4):255-259. doi:
10.3760/cma.j.cn121094-20210202-00073. [PMID: 35545590] - Delon W Barfuss, John T Buchanan, Lucy Joshee, Elizabeth H Pittman, Nigel D'Souza, Kayla E Matta, Ryan T Brownlee, Christy C Bridges. Hepatic processing of mercuric ions facilitates delivery to renal proximal tubules.
Toxicology letters.
2022 Apr; 359(?):1-9. doi:
10.1016/j.toxlet.2022.01.009. [PMID: 35066093] - Sunil P Trivedi, Shefalee Singh, Abha Trivedi, Manoj Kumar. Mercuric chloride-induced oxidative stress, genotoxicity, haematological changes and histopathological alterations in fish Channa punctatus (Bloch, 1793).
Journal of fish biology.
2022 Apr; 100(4):868-883. doi:
10.1111/jfb.15019. [PMID: 35195905] - Tareq Nayef AlRamadneh, Naif AlQurashi, Mohd Sajjad Ahmad Khan, Saeed Mujahid Hashimi, Rajesh Javaraiah, Fares Hezam Al-Ostoot, Abed Alkarem Abu Alhaija. Flaxseed oil ameliorates mercuric chloride-induced liver damage in rats.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2022 Feb; 71(?):126965. doi:
10.1016/j.jtemb.2022.126965. [PMID: 35278998] - Rafa S Almeer, Saad Alkahtani, Saud Alarifi, Ahmed E Abdel Moneim, Saba Abdi, Gadah Albasher. Ziziphus spina-christi Leaf Extract Mitigates Mercuric Chloride-induced Cortical Damage in Rats.
Combinatorial chemistry & high throughput screening.
2022; 25(1):103-113. doi:
10.2174/1386207323666201204124412. [PMID: 33280592] - Kleber Ribeiro Fidelis, Ricardo Gomes Dos Santos Nunes, Cícera Simoni da Silva, Carlos Vinicius Barros Oliveira, Adrielle Rodrigues Costa, Jailson Renato de Lima Silva, Larisse Bernardino Dos Santos, Elayne Eally Silva de Oliveira, Pedro Silvino Pereira, Irwin Rose Alencar de Menezes, Jean Paul Kamdem, Antônia Eliene Duarte, Antônio Ivanildo Pinho, Luiz Marivando Barros. Evaluation of the neuroprotective effect of rutin on Drosophila melanogaster about behavioral and biochemical aspects induced by mercury chloride (HgCl2).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2021 Nov; 249(?):109119. doi:
10.1016/j.cbpc.2021.109119. [PMID: 34182094] - Xinyue Xu, Zhongxian Yu, Biqi Han, Siyu Li, Yingshuo Sun, Yu Du, Ziwei Wang, Di Gao, Zhigang Zhang. Luteolin alleviates inorganic mercury-induced kidney injury via activation of the AMPK/mTOR autophagy pathway.
Journal of inorganic biochemistry.
2021 11; 224(?):111583. doi:
10.1016/j.jinorgbio.2021.111583. [PMID: 34428638] - Vanessa Blas-Valdivia, Plácido Rojas-Franco, Jose Ivan Serrano-Contreras, Andrea Augusto Sfriso, Cristian Garcia-Hernandez, Margarita Franco-Colín, Edgar Cano-Europa. C-phycoerythrin from Phormidium persicinum Prevents Acute Kidney Injury by Attenuating Oxidative and Endoplasmic Reticulum Stress.
Marine drugs.
2021 Oct; 19(11):. doi:
10.3390/md19110589. [PMID: 34822460] - Victória Dos Santos Chemelo, Leonardo Oliveira Bittencourt, Walessa Alana Bragança Aragão, Sávio Monteiro Dos Santos, Renata Duarte Souza-Rodrigues, Carolina Heitmann Mares Azevedo Ribeiro, Marta Chagas Monteiro, Rafael Rodrigues Lima. Long-Term Exposure to Inorganic Mercury Leads to Oxidative Stress in Peripheral Blood of Adult Rats.
Biological trace element research.
2021 Aug; 199(8):2992-3000. doi:
10.1007/s12011-020-02411-5. [PMID: 32997227] - Janaina E Rocha, Tássia T A M Guedes, Camila F Bezerra, Maria do S Costa, Fabia F Campina, Thiago S de Freitas, Amanda K Sousa, Celestina E Sobral Souza, Maria K N Silva, Yedda M Lobo, Francisco N Pereira-Junior, João H da Silva, Irwin R A Menezes, Raimundo N P Teixeira, Aracélio V Colares, Henrique D M Coutinho. FTIR analysis of pyrogallol and phytotoxicity-reductive effect against mercury chloride.
Environmental geochemistry and health.
2021 Jun; 43(6):2433-2442. doi:
10.1007/s10653-020-00607-1. [PMID: 32488795] - João Vitor Dos Anjos Vieira, Vinicius Bermond Marques, Luiza Valli Vieira, Renato de Oliveira Crajoinas, Maria Heloisa Massola Shimizu, Antonio Carlos Seguro, Maria Tereza Weitzel Dias Carneiro, Adriana Castello Costa Girardi, Dalton Valentim Vassallo, Leonardo Dos Santos. Changes in the renal function after acute mercuric chloride exposure in the rat are associated with renal vascular endothelial dysfunction and proximal tubule NHE3 inhibition.
Toxicology letters.
2021 May; 341(?):23-32. doi:
10.1016/j.toxlet.2021.01.014. [PMID: 33476711] - Shimaa S Ramadan, Rafa S Almeer, Saad Alkahtani, Saud Alarifi, Gadah Albasher, Ahmed E Abdel Moneim. Ziziphus spina-christi leaf extract attenuates mercuric chloride-induced liver injury in male rats via inhibition of oxidative damage.
Environmental science and pollution research international.
2021 Apr; 28(14):17482-17494. doi:
10.1007/s11356-020-12160-6. [PMID: 33394435] - Joelma P da Silva, Maria do S Costa, Fabia F Campina, Camila F Bezerra, Thiago S de Freitas, Amanda K Sousa, Celestina E Sobral Souza, Yedda M L S de Matos, Francisco N Pereira-Junior, Irwim R A Menezes, Henrique D M Coutinho, Janaína E Rocha. Evaluation of chelating and cytoprotective activity of vanillin against the toxic action of mercuric chloride as an alternative for phytoremediation.
Environmental geochemistry and health.
2021 Apr; 43(4):1609-1616. doi:
10.1007/s10653-020-00538-x. [PMID: 32130595] - M H Hazelhoff, A M Torres. Effect of erythropoietin on mercury-induced nephrotoxicity: Role of membrane transporters.
Human & experimental toxicology.
2021 Mar; 40(3):515-525. doi:
10.1177/0960327120958109. [PMID: 32909846] - Gennaro Lettieri, Rosaria Notariale, Alessia Ambrosino, Alfredo Di Bonito, Antonella Giarra, Marco Trifuoggi, Caterina Manna, Marina Piscopo. Spermatozoa Transcriptional Response and Alterations in PL Proteins Properties after Exposure of Mytilus galloprovincialis to Mercury.
International journal of molecular sciences.
2021 Feb; 22(4):. doi:
10.3390/ijms22041618. [PMID: 33562685] - Jan Magdalan, Tomasz Sozański, Karolina Nowak, Marcin Zawadzki. Acute intranasal intoxication with mercuric chloride taken accidently instead of cocaine - A case report.
Journal of forensic and legal medicine.
2021 Feb; 78(?):102129. doi:
10.1016/j.jflm.2021.102129. [PMID: 33581407] - Mehdi Amirhosseini, Hammoudi Alkaissi, Per A Hultman, Said Havarinasab. Autoantibodies in outbred Swiss Webster mice following exposure to gold and mercury.
Toxicology and applied pharmacology.
2021 02; 412(?):115379. doi:
10.1016/j.taap.2020.115379. [PMID: 33358697] - Yu Rohovyi, V Tsitrin, L Arkchipova, V Bilookyi, O Kolesnik. [THE USE OF MOLECULAR HYDROGEN IN CORRECTION OF NO-REFLOW SYNDROME IN THE POLYURIC STAGE OF SUBLIMATE NEPHROPATHY].
Georgian medical news.
2021 Feb; ?(311):156-162. doi:
. [PMID: 33814411] - Aceng Ruyani, Eda Kartika, Deni Parlindungan, Riza Julian Putra, Agus Sundaryono, Agus Susanta. Leaf ethanolic extract of Etlingera hemesphaerica Blume mitigates defects in fetal anatomy and endochondral ossification due to mercuric chloride during the post-implantation period in Mus musculus.
PloS one.
2021; 16(3):e0247467. doi:
10.1371/journal.pone.0247467. [PMID: 33690696] - María Herminia Hazelhoff, Romina Paula Bulacio, Adriana Monica Torres. Trimetazidine Protects from Mercury-Induced Kidney Injury.
Pharmacology.
2021; 106(5-6):332-340. doi:
10.1159/000514843. [PMID: 33849026] - Ji-Won Jang, Seunghyung Lee, Bong-Joo Lee, Sang-Woo Hur, Maeng-Hyun Son, Kang-Woong Kim, Kyoung-Duck Kim, Hyon-Sob Han. A comparative study of effects of dietary mercuric chloride and methylmercury chloride on growth performance, tissue accumulation, stress and immune responses, and plasma measurements in Korean rockfish, Sebastes schlegeli.
Chemosphere.
2020 Dec; 260(?):127611. doi:
10.1016/j.chemosphere.2020.127611. [PMID: 32758780] - Jia-Hong Chu, Yu-Xue Yan, Pei-Chao Gao, Xue-Wei Chen, Rui-Feng Fan. Response of selenoproteins gene expression profile to mercuric chloride exposure in chicken kidney.
Research in veterinary science.
2020 Dec; 133(?):4-11. doi:
10.1016/j.rvsc.2020.08.020. [PMID: 32916514] - Hannah Sørine Gerlich, Martin Holmstrup, Poul Bjerregaard, Stine Slotsbo. Mercury (Hg2+) interferes with physiological adaptations to freezing in the arctic earthworm Enchytraeus albidus.
Ecotoxicology and environmental safety.
2020 Nov; 204(?):111005. doi:
10.1016/j.ecoenv.2020.111005. [PMID: 32738624] - Yan Ma, Yizhen Shi, Xiaoting Zou, Qiujue Wu, Jianping Wang. Apoptosis induced by mercuric chloride is associated with upregulation of PERK-ATF4-CHOP pathway in chicken embryonic kidney cells.
Poultry science.
2020 Nov; 99(11):5802-5813. doi:
10.1016/j.psj.2020.06.084. [PMID: 33142498] - Vitor Antunes Oliveira, Nayara de Souza da Costa, Mariana Mesquita, Taíse Fonseca Pedroso, Tiago da Luz Fiuza, Nilce Coelho Peixoto, Maria Ester Pereira, Cláudia Sirlene Oliveira. Mercury toxicity in pregnant and lactating rats: zinc and N-acetylcysteine as alternative of prevention.
Environmental science and pollution research international.
2020 Nov; 27(32):40563-40572. doi:
10.1007/s11356-020-09836-4. [PMID: 32671705] - Rui Li, Han Wu, Jing Ding, Nan Li, Weimin Fu, Lijun Gan, Yi Li. Transgenic merA and merB expression reduces mercury contamination in vegetables and grains grown in mercury-contaminated soil.
Plant cell reports.
2020 Oct; 39(10):1369-1380. doi:
10.1007/s00299-020-02570-8. [PMID: 32712731] - Lujing Geng, Zhenghua Xia, Lu Yuan, Cen Li, Ming Zhang, Yuzhi Du, Lixin Wei, Hongtao Bi. Effects of β-HgS on cell viability and intracellular oxidative stress in PC-12 cells.
Metallomics : integrated biometal science.
2020 09; 12(9):1389-1399. doi:
10.1039/d0mt00088d. [PMID: 32638798] - Siwen Li, Mei Shi, Ying Wan, Yanling Wang, Mei Zhu, Boya Wang, Yangmei Zhan, Bing Ran, Chunling Wu. Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
Ecotoxicology and environmental safety.
2020 Sep; 201(?):110801. doi:
10.1016/j.ecoenv.2020.110801. [PMID: 32502906] - Gadah Albasher, Saad Alkahtani, Saud Alarifi. Berberine mitigates oxidative damage associated with testicular impairment following mercury chloride intoxication.
Journal of food biochemistry.
2020 09; 44(9):e13385. doi:
10.1111/jfbc.13385. [PMID: 33460233] - Patric Schyman, Richard L Printz, Mohamed Diwan M AbdulHameed, Shanea K Estes, Chiyo Shiota, Masakazu Shiota, Anders Wallqvist. A toxicogenomic approach to assess kidney injury induced by mercuric chloride in rats.
Toxicology.
2020 09; 442(?):152530. doi:
10.1016/j.tox.2020.152530. [PMID: 32599119] - Chetan Malik, Subhendu Ghosh. Regulation of Single-Channel Conductance of Voltage-Dependent Anion Channel by Mercuric Chloride in a Planar Lipid Bilayer.
The Journal of membrane biology.
2020 08; 253(4):357-371. doi:
10.1007/s00232-020-00134-1. [PMID: 32748041] - Shiva Roshankhah, Amir Abdolmaleki, Mohammad Reza Salahshoor. Anti-inflammatory, anti-apoptotic, and antioxidant actions of Middle Eastern Phoenix dactylifera extract on mercury-induced hepatotoxicity in vivo.
Molecular biology reports.
2020 Aug; 47(8):6053-6065. doi:
10.1007/s11033-020-05680-4. [PMID: 32737827] - Shaukat Ali, Zubia Awan, Shumaila Mumtaz, Hafiz Abdullah Shakir, Farooq Ahmad, Mazhar Ulhaq, Hafiz Muhammad Tahir, Muhammad Siddique Awan, Saima Sharif, Muhammad Irfan, Muhammad Adeeb Khan. Cardiac toxicity of heavy metals (cadmium and mercury) and pharmacological intervention by vitamin C in rabbits.
Environmental science and pollution research international.
2020 Aug; 27(23):29266-29279. doi:
10.1007/s11356-020-09011-9. [PMID: 32436095] - Laila M Fadda, Ahlam M Alhusaini, Qamraa H Al-Qahtani, Hanaa M Ali, Iman H Hasan. Role of α-tocopherol and Lactobacillus plantarum in the alleviation of mercuric chloride-induced testicular atrophy in rat's model: Implication of molecular mechanisms.
Journal of biochemical and molecular toxicology.
2020 Jun; 34(6):e22481. doi:
10.1002/jbt.22481. [PMID: 32134168] - Rania Waheed, Amel M El Asely, Hatem Bakery, Ragab El-Shawarby, Mohamed Abuo-Salem, Nabila Abdel-Aleem, Farag Malhat, Asmaa Khafaga, Ahmed Abdeen. Thermal stress accelerates mercury chloride toxicity in Oreochromis niloticus via up-regulation of mercury bioaccumulation and HSP70 mRNA expression.
The Science of the total environment.
2020 May; 718(?):137326. doi:
10.1016/j.scitotenv.2020.137326. [PMID: 32092518] - Sarah E Orr, Hannah S George, Mary C Barnes, Taylor N Mathis, Lucy Joshee, Jennifer Barkin, Adam M Kiefer, Caryn S Seney, Christy C Bridges. Co-administration of Selenium with Inorganic Mercury Alters the Disposition of Mercuric Ions in Rats.
Biological trace element research.
2020 May; 195(1):187-195. doi:
10.1007/s12011-019-01835-y. [PMID: 31332705] - Khalad Maliyar, Patrick Fleming, Boluwaji Ogunyemi, Charles Lynde. A Brief History of Psoriasis Management in Canada.
Journal of cutaneous medicine and surgery.
2020 May; 24(3):273-277. doi:
10.1177/1203475420903682. [PMID: 32003582] - Arifa Rahman, Yukio Kawamura, Masayoshi Maeshima, Abidur Rahman, Matsuo Uemura. Plasma Membrane Aquaporin Members PIPs Act in Concert to Regulate Cold Acclimation and Freezing Tolerance Responses in Arabidopsis thaliana.
Plant & cell physiology.
2020 Apr; 61(4):787-802. doi:
10.1093/pcp/pcaa005. [PMID: 31999343] - Ladan Behzadfar, Shokoufeh Hassani, Hossein Feizpour, Nakisa Abbasian, Armin Salek Maghsoudi, Ghorban Taghizadeh, Jalal Pourahmad, Mohammad Sharifzadeh. Effects of mercuric chloride on spatial memory deficit-induced by beta-amyloid and evaluation of mitochondrial function markers in the hippocampus of rats.
Metallomics : integrated biometal science.
2020 01; 12(1):144-153. doi:
10.1039/c9mt00161a. [PMID: 31793599] - Anja Kavčič, Bojan Budič, Katarina Vogel-Mikuš. The effects of selenium biofortification on mercury bioavailability and toxicity in the lettuce-slug food chain.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2020 Jan; 135(?):110939. doi:
10.1016/j.fct.2019.110939. [PMID: 31697969] - Rafa S Almeer, Gadah Albasher, Rami B Kassab, Shaimaa R Ibrahim, Fatimah Alotibi, Saud Alarifi, Daoud Ali, Saad Alkahtani, Ahmed E Abdel Moneim. Ziziphus spina-christi leaf extract attenuates mercury chloride-induced testicular dysfunction in rats.
Environmental science and pollution research international.
2020 Jan; 27(3):3401-3412. doi:
10.1007/s11356-019-07237-w. [PMID: 31840221] - Yuxin Zhong, Baoqiang Wang, Shan Hu, Tingting Wang, Yumiao Zhang, Jinling Wang, Yuqing Liu, Hongxia Zhang. The role of endoplasmic reticulum stress in renal damage caused by acute mercury chloride poisoning.
The Journal of toxicological sciences.
2020; 45(9):589-598. doi:
10.2131/jts.45.589. [PMID: 32879258] - O Owoeye, F I Obazie, Foluso Ayobami Atiba, Adefolarin Obanisola Malomo. Comparative Neuroprotective Effect of Celosia argentea Linn. and Vitamin E on Mercury-induced Oxidative and Histological Parameters of Rat Brain.
Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria.
2019 Dec; 34(2):167-175. doi:
. [PMID: 32343268] - Cuneyt Caglayan, Fatih Mehmet Kandemir, Ekrem Darendelioğlu, Serkan Yıldırım, Sefa Kucukler, Muhammet Bahaeddin Dortbudak. Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2019 Dec; 56(?):60-68. doi:
10.1016/j.jtemb.2019.07.011. [PMID: 31442956] - Tareq Aqeel, Sunil Chikkalakshmipura Gurumallu, Saeed Mujahid Hashimi, Naif AlQurashi, Rajesh Javaraiah. Evaluation of protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside against mercuric chloride-induced nephrotoxicity in rats.
Molecular biology reports.
2019 Dec; 46(6):6171-6179. doi:
10.1007/s11033-019-05052-7. [PMID: 31493285] - Xiaoliang Zhao, Lijie Gao, Jiayan Ren, Fei Pan. Arabidopsis SIMILAR TO RCD-ONE genes are ubiquitous and respond to multiple abiotic stresses through diverse signaling pathways.
Journal of biosciences.
2019 Dec; 44(6):. doi:
10.1007/s12038-019-9946-7. [PMID: 31894110] - Sarwat Jahan, Tayyaba Azad, Amina Ayub, Asad Ullah, Tayyaba Afsar, Ali Almajwal, Suhail Razak. Ameliorating potency of Chenopodium album Linn. and vitamin C against mercuric chloride-induced oxidative stress in testes of Sprague Dawley rats.
Environmental health and preventive medicine.
2019 Nov; 24(1):62. doi:
10.1186/s12199-019-0820-x. [PMID: 31759394] - Siwen Li, Xia Jiang, Yonghong Luo, Bingru Zhou, Mei Shi, Fangyuan Liu, Ailong Sha. Sodium/calcium overload and Sirt1/Nrf2/OH-1 pathway are critical events in mercuric chloride-induced nephrotoxicity.
Chemosphere.
2019 Nov; 234(?):579-588. doi:
10.1016/j.chemosphere.2019.06.095. [PMID: 31229719] - Siyu Li, Ruiqi Baiyun, Zhanjun Lv, Jiayi Li, Dongxu Han, Wenyue Zhao, Lanjie Yu, Ning Deng, Zhiyan Liu, Zhigang Zhang. Exploring the kidney hazard of exposure to mercuric chloride in mice:Disorder of mitochondrial dynamics induces oxidative stress and results in apoptosis.
Chemosphere.
2019 Nov; 234(?):822-829. doi:
10.1016/j.chemosphere.2019.06.096. [PMID: 31247492] - Eduardo Merlo, Ingridy R G Schereider, Maylla R Simões, Dalton V Vassallo, Jones B Graceli. Mercury leads to features of polycystic ovary syndrome in rats.
Toxicology letters.
2019 Sep; 312(?):45-54. doi:
10.1016/j.toxlet.2019.05.006. [PMID: 31071422] - Cuneyt Caglayan, Fatih Mehmet Kandemir, Serkan Yildirim, Sefa Kucukler, Gizem Eser. Rutin protects mercuric chloride-induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2019 Jul; 54(?):69-78. doi:
10.1016/j.jtemb.2019.04.007. [PMID: 31109623] - Celestina E Sobral-Souza, Ana R P Silva, Nadghia F Leite, José G M Costa, Irwin R A Menezes, Francisco A B Cunha, Larissa A Rolim, Henrique D M Coutinho. LC-MS analysis and cytoprotective effect against the mercurium and aluminium toxicity by bioactive products of Psidium brownianum Mart. ex DC.
Journal of hazardous materials.
2019 May; 370(?):54-62. doi:
10.1016/j.jhazmat.2018.03.039. [PMID: 29602643] - Zhengli Yang, Yifan Zhao, Qian Li, Yiming Shao, Xinchun Yu, Wei Cong, Xiaodong Jia, Weidong Qu, Longzhen Cheng, Peng Xue, Zhijun Zhou, Miao He, Yubin Zhang. Developmental exposure to mercury chloride impairs social behavior in male offspring dependent on genetic background and maternal autoimmune environment.
Toxicology and applied pharmacology.
2019 05; 370(?):1-13. doi:
10.1016/j.taap.2019.03.006. [PMID: 30862457] - Danize Aparecida Rizzetti, Patricia Corrales, Janaina Trindade Piagette, José Antonio Uranga-Ocio, Gema Medina-Gomez, Franck Maciel Peçanha, Dalton Valentim Vassallo, Marta Miguel, Giulia Alessandra Wiggers. Chronic mercury at low doses impairs white adipose tissue plasticity.
Toxicology.
2019 04; 418(?):41-50. doi:
10.1016/j.tox.2019.02.013. [PMID: 30807803] - Celestina E Sobral-Souza, Ana R P Silva, Nadghia F Leite, Janaina E Rocha, Amanda K Sousa, José G M Costa, Irwin R A Menezes, Francisco A B Cunha, Larissa A Rolim, Henrique D M Coutinho. Phytotoxicity reduction of the mercury chloride effect by natural products from Eugenia jambolana Lam.: A new strategy against the toxic metal pollution.
Ecotoxicology and environmental safety.
2019 Apr; 170(?):461-467. doi:
10.1016/j.ecoenv.2018.12.007. [PMID: 30553924] - Sarah E Orr, Mary C Barnes, Lucy Joshee, Olga Uchakina, Robert J McKallip, Christy C Bridges. Potential mechanisms of cellular injury following exposure to a physiologically relevant species of inorganic mercury.
Toxicology letters.
2019 Apr; 304(?):13-20. doi:
10.1016/j.toxlet.2019.01.003. [PMID: 30630035] - Samar S Elblehi, Mona H Hafez, Yasser S El-Sayed. L-α-Phosphatidylcholine attenuates mercury-induced hepato-renal damage through suppressing oxidative stress and inflammation.
Environmental science and pollution research international.
2019 Mar; 26(9):9333-9342. doi:
10.1007/s11356-019-04395-9. [PMID: 30721437] - Shahbaz Ahmad, Riaz Mahmood. Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma membrane redox system.
Environmental science and pollution research international.
2019 Feb; 26(6):5645-5657. doi:
10.1007/s11356-018-04062-5. [PMID: 30612358] - Kabita Gogoi, Prasenjit Manna, Tapan Dey, Jatin Kalita, Bala Gopalan Unni, Dibyajyoti Ozah, Pranab Kumar Baruah. Circulatory heavy metals (cadmium, lead, mercury, and chromium) inversely correlate with plasma GST activity and GSH level in COPD patients and impair NOX4/Nrf2/GCLC/GST signaling pathway in cultured monocytes.
Toxicology in vitro : an international journal published in association with BIBRA.
2019 Feb; 54(?):269-279. doi:
10.1016/j.tiv.2018.10.010. [PMID: 30359721] - Shaukat Ali, Sidra Hussain, Rida Khan, Shumaila Mumtaz, Nasra Ashraf, Saiqa Andleeb, Hafiz Abdullah Shakir, Hafiz Muhammad Tahir, Muhammad Khalil Ahmad Khan, Mazhar Ulhaq. Renal toxicity of heavy metals (cadmium and mercury) and their amelioration with ascorbic acid in rabbits.
Environmental science and pollution research international.
2019 Feb; 26(4):3909-3920. doi:
10.1007/s11356-018-3819-8. [PMID: 30547340] - Aceng Ruyani, Rendi Zulni Eka Putri, Pauzi Jundara, Efri Gresinta, Irwandi Ansori, Agus Sundaryono. Protective Effect of Leaf Ethanolic Extract Etlingera hemisphaerica Blume Against Mercuric Chloride Toxicity in Blood of Mice.
Journal of dietary supplements.
2019; 16(1):51-65. doi:
10.1080/19390211.2018.1429516. [PMID: 29451842] - Rafa S Almeer, Gadah Albasher, Fatimah Alotibi, Saud Alarifi, Daoud Ali, Saad Alkahtani. Ziziphus spina-christi Leaf Extract Suppressed Mercury Chloride-Induced Nephrotoxicity via Nrf2-Antioxidant Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling.
Oxidative medicine and cellular longevity.
2019; 2019(?):5634685. doi:
10.1155/2019/5634685. [PMID: 31827681] - Weiwei Zhang, Xuezhen Jiang, Shuang Zhao, Xiaojie Zheng, Jin Lan, Hexiang Wang, Tzi Bun Ng. A polysaccharide-peptide with mercury clearance activity from dried fruiting bodies of maitake mushroom Grifola frondosa.
Scientific reports.
2018 12; 8(1):17630. doi:
10.1038/s41598-018-35945-9. [PMID: 30514871] - Tiago da Luz Fiuza, Jossiele Leitemperger, Eduardo Stringini Severo, Aline Teixeira Marins, Aline Blank do Amaral, Maria Ester Pereira, Vania Lucia Loro. Effects of diphenyl diselenide diet on a model of mercury poisoning.
Molecular biology reports.
2018 Dec; 45(6):2631-2639. doi:
10.1007/s11033-018-4433-z. [PMID: 30353476] - Zhiping Che, Yuee Tian, Shengming Liu, Jia Jiang, Mei Hu, Genqiang Chen. Microwave-Assisted Expeditious Synthesis of 2-Alkyl-2-(N-arylsulfonylindol-3-yl)-3-N-acyl-5-aryl-1,3,4-oxadiazolines Catalyzed by HgCl₂ under Solvent-Free Conditions as Potential Anti-HIV-1 Agents.
Molecules (Basel, Switzerland).
2018 Nov; 23(11):. doi:
10.3390/molecules23112936. [PMID: 30423803] - Hurrem Turan Akkoyun. Effect of boric acid on some elemental levels on rat's liver and kidney tissues during mercury chloride exposure.
Cellular and molecular biology (Noisy-le-Grand, France).
2018 Oct; 64(13):84-88. doi:
10.14715/cmb/2018.64.13.16. [PMID: 30403601] - Y-J Shin, K-A Kim, E-S Kim, J-H Kim, H-S Kim, M Ha, O-N Bae. Identification of aldo-keto reductase (AKR7A1) and glutathione S-transferase pi (GSTP1) as novel renal damage biomarkers following exposure to mercury.
Human & experimental toxicology.
2018 Oct; 37(10):1025-1036. doi:
10.1177/0960327117751234. [PMID: 29298499] - Y Ma, Y X Zheng, X Y Dong, X T Zou. Effect of mercury chloride on oxidative stress and nuclear factor erythroid 2-related factor 2 signalling molecule in liver and kidney of laying hens.
Journal of animal physiology and animal nutrition.
2018 Oct; 102(5):1199-1209. doi:
10.1111/jpn.12920. [PMID: 29974977] - Yan Ma, Yizhen Shi, Lanlan Li, Chao Xie, Xiaoting Zou. Toxicological Effects of Mercury Chloride on Laying Performance, Egg Quality, Serum Biochemistry, and Histopathology of Liver and Kidney in Laying Hens.
Biological trace element research.
2018 Oct; 185(2):465-474. doi:
10.1007/s12011-018-1263-8. [PMID: 29427036] - María H Hazelhoff, Romina P Bulacio, Alberto Chevalier, Adriana M Torres. Renal expression of organic anion transporters is modified after mercuric chloride exposure: Gender-related differences.
Toxicology letters.
2018 Oct; 295(?):390-396. doi:
10.1016/j.toxlet.2018.07.016. [PMID: 30031051] - Qiaozhu Tan, Zhitao Liu, Hong Li, Yongjun Liu, Zhenghua Xia, Yuancan Xiao, Muhammad Usman, Yuzhi Du, Hongtao Bi, Lixin Wei. Hormesis of mercuric chloride-human serum albumin adduct on N9 microglial cells via the ERK/MAPKs and JAK/STAT3 signaling pathways.
Toxicology.
2018 09; 408(?):62-69. doi:
10.1016/j.tox.2018.07.001. [PMID: 29981841] - Sunny O Abarikwu, Rex-Clovis C Njoku, Chigozie L Onuah. Aged coconut oil with a high peroxide value induces oxidative stress and tissue damage in mercury-treated rats.
Journal of basic and clinical physiology and pharmacology.
2018 Jul; 29(4):365-376. doi:
10.1515/jbcpp-2016-0138. [PMID: 29570447] - Yiling Li, Bin He, Qiying Nong, Guangbo Qu, Lihong Liu, Jianbo Shi, Ligang Hu, Guibin Jiang. Characterization of mercury-binding proteins in rat blood plasma.
Chemical communications (Cambridge, England).
2018 Jul; 54(54):7439-7442. doi:
10.1039/c8cc02144a. [PMID: 29771257] - Yaling Sun, Yingwen Li, Jiedan Rao, Zhihao Liu, Qiliang Chen. Effects of inorganic mercury exposure on histological structure, antioxidant status and immune response of immune organs in yellow catfish (Pelteobagrus fulvidraco).
Journal of applied toxicology : JAT.
2018 06; 38(6):843-854. doi:
10.1002/jat.3592. [PMID: 29380397] - Laís Pessanha de Carvalho, Edésio José Tenório de Melo. Further aspects of Toxoplasma gondii elimination in the presence of metals.
Parasitology research.
2018 Apr; 117(4):1245-1256. doi:
10.1007/s00436-018-5806-x. [PMID: 29455419] - Sh Mohammadi, M Gholamin, M Mohammadi, A Mansouri, R Mahmoodian, S Attari, S M Kebriaei, B Zibaei, M Roshanaei, F Daneshvar, M Khandehro, M A Khodadadegan, A Delshad, F Mohammadzadeh, Mostafa Peyvandi, Majid Ghayour-Mobarhan, Shima Tavallaie, Samaneh Boroumand-Noughabi, Gordon A A Ferns. Down-regulation of CatSper 1 and CatSper 2 genes by lead and mercury.
Environmental toxicology and pharmacology.
2018 Apr; 59(?):82-86. doi:
10.1016/j.etap.2018.03.007. [PMID: 29549816] - Evan Kerek, Mohamed Hassanin, Elmar J Prenner. Inorganic mercury and cadmium induce rigidity in eukaryotic lipid extracts while mercury also ruptures red blood cells.
Biochimica et biophysica acta. Biomembranes.
2018 Mar; 1860(3):710-717. doi:
10.1016/j.bbamem.2017.12.014. [PMID: 29269315] - Xue Wang, Lifeng Han, Gentao Li, Wei Peng, Xiumei Gao, Curtis D Klaassen, Guanwei Fan, Youcai Zhang. From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 02; 161(2):321-334. doi:
10.1093/toxsci/kfx216. [PMID: 29045746] - Xiao Tan, Biying Liu, Jingjing Lu, Siyu Li, Ruiqi Baiyun, Yueying Lv, Qian Lu, Zhigang Zhang. Dietary luteolin protects against HgCl2-induced renal injury via activation of Nrf2-mediated signaling in rat.
Journal of inorganic biochemistry.
2018 02; 179(?):24-31. doi:
10.1016/j.jinorgbio.2017.11.010. [PMID: 29156292] - Lucélia Moraes-Silva, Cláudia Sirlene Oliveira, Nilce Coelho Peixoto, Maria Ester Pereira. Copper attenuates early and late biochemical alterations induced by inorganic mercury in young rats.
Journal of toxicology and environmental health. Part A.
2018; 81(14):633-644. doi:
10.1080/15287394.2018.1474153. [PMID: 29842829] - Cen Li, Wei Xu, Shengqi Chu, Zhiyuan Zheng, Yuancan Xiao, Linshuai Li, Hongtai Bi, Lixin Wei. The chemical speciation, spatial distribution and toxicity of mercury from Tibetan medicine Zuotai，β-HgS and HgCl2 in mouse kidney.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2018 Jan; 45(?):104-113. doi:
10.1016/j.jtemb.2017.08.010. [PMID: 29173465] - Maki Tokumoto, Jin-Yong Lee, Akinori Shimada, Chiharu Tohyama, Masahiko Satoh. Glutathione has a more important role than metallothionein-I/II against inorganic mercury-induced acute renal toxicity.
The Journal of toxicological sciences.
2018; 43(4):275-280. doi:
10.2131/jts.43.275. [PMID: 29618716] - Danize Aparecida Rizzetti, Ángela Martín, Patricia Corrales, Francisca Fernandez, Maylla Ronacher Simões, Franck Maciel Peçanha, Dalton Valentim Vassallo, Marta Miguel, Giulia Alessandra Wiggers. Egg white-derived peptides prevent cardiovascular disorders induced by mercury in rats: Role of angiotensin-converting enzyme (ACE) and NADPH oxidase.
Toxicology letters.
2017 Nov; 281(?):158-174. doi:
10.1016/j.toxlet.2017.10.001. [PMID: 28987480] - Olatunde Owoeye, Ganiyu O Arinola. A Vegetable, Launaea taraxacifolia, Mitigated Mercuric Chloride Alteration of the Microanatomy of Rat Brain.
Journal of dietary supplements.
2017 Nov; 14(6):613-625. doi:
10.1080/19390211.2017.1288194. [PMID: 28471730] - Bin-Bin Zhang, Shang-Fu Xu, Ya-Sha Xu, Yuan-Fu Lu, Li-Xin Wei, Jie Liu. [Effect of Zuotai and HgS on gene expression of drug-metabolizing enzymes in livers of mice].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2017 Nov; 42(21):4195-4200. doi:
10.19540/j.cnki.cjcmm.20170928.015. [PMID: 29271160] - W A B Aragão, N M M da Costa, N C F Fagundes, M C F Silva, S M Alves-Junior, J J V Pinheiro, L L Amado, M E Crespo-López, C S F Maia, R R Lima. Chronic exposure to inorganic mercury induces biochemical and morphological changes in the salivary glands of rats.
Metallomics : integrated biometal science.
2017 09; 9(9):1271-1278. doi:
10.1039/c7mt00123a. [PMID: 28795724] - Bin-Bin Zhang, Wen-Kai Li, Wei-Yu Hou, Ya Luo, Jing-Zhen Shi, Cen Li, Li-Xin Wei, Jie Liu. Zuotai and HgS differ from HgCl2 and methyl mercury in Hg accumulation and toxicity in weanling and aged rats.
Toxicology and applied pharmacology.
2017 09; 331(?):76-84. doi:
10.1016/j.taap.2017.05.021. [PMID: 28536007] - Yu Qiao, Xi Huang, Beibei Chen, Man He, Bin Hu. In vitro study on antagonism mechanism of glutathione, sodium selenite and mercuric chloride.
Talanta.
2017 Aug; 171(?):262-269. doi:
10.1016/j.talanta.2017.04.074. [PMID: 28551139] - Ji-Li Yuan, Yan-Yan Tao, Qing-Lan Wang, Li Shen, Cheng-Hai Liu. Fuzheng Huayu Formula () prevents rat renal interstitial fibrosis induced by HgCl2 via antioxidative stress and down-regulation of nuclear factor-kappa B activity.
Chinese journal of integrative medicine.
2017 Aug; 23(8):598-604. doi:
10.1007/s11655-016-2540-z. [PMID: 28197934] - Sunny O Abarikwu, Sussan Benjamin, Sunday Godspower Ebah, Godbless Obilor, Goodluck Agbam. Protective effect of Moringa oleifera oil against HgCl2-induced hepato- and nephro-toxicity in rats.
Journal of basic and clinical physiology and pharmacology.
2017 Jul; 28(4):337-345. doi:
10.1515/jbcpp-2016-0033. [PMID: 28306528] - Deepmala Joshi, Deepak Kumar Mittal, Sangeeta Shukla, Sunil Kumar Srivastav, Vaibhav A Dixit. Curcuma longa Linn. extract and curcumin protect CYP 2E1 enzymatic activity against mercuric chloride-induced hepatotoxicity and oxidative stress: A protective approach.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2017 Jul; 69(6):373-382. doi:
10.1016/j.etp.2017.02.009. [PMID: 28336172] - Deepmala Joshi, Sunil Kumar Srivastav, Sateesh Belemkar, Vaibhav A Dixit. Zingiber officinale and 6-gingerol alleviate liver and kidney dysfunctions and oxidative stress induced by mercuric chloride in male rats: A protective approach.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Jul; 91(?):645-655. doi:
10.1016/j.biopha.2017.04.108. [PMID: 28494418] - Vitor Antunes Oliveira, Gaia Favero, Alessandra Stacchiotti, Lorena Giugno, Barbara Buffoli, Claudia Sirlene de Oliveira, Antonio Lavazza, Massimo Albanese, Luigi Fabrizio Rodella, Maria Ester Pereira, Rita Rezzani. Acute mercury exposition of virgin, pregnant, and lactating rats: Histopathological kidney and liver evaluations.
Environmental toxicology.
2017 May; 32(5):1500-1512. doi:
10.1002/tox.22370. [PMID: 27726300]