Sodium hydrogen carbonate (BioDeep_00000009362)
Secondary id: BioDeep_00001871293
human metabolite Volatile Flavor Compounds
代谢物信息卡片
Sodium hydrogen carbonic acid
化学式: NaHCO3 (83.9823396)
中文名称: 碳酸氢钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=O)(O)[O-].[Na+]
InChI: /q
描述信息
Leavening agent; component of self-raising flour. pH control agent for foods. Sodium bicarbonate or sodium hydrogen carbonate is the chemical compound with the formula NaHCO3. Sodium bicarbonate is a white solid that is crystalline but often appears as a fine powder. It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate). It is a component of the mineral natron and is found dissolved in many mineral springs. The natural mineral form, nahcolite, is found in dissolved form in bile, where it serves to neutralize the acidity of the hydrochloric acid produced by the stomach, and is excreted into the duodenum of the small intestine via the bile duct. It is also produced artificially.
B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05X - I.v. solution additives > B05XA - Electrolyte solutions
B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05C - Irrigating solutions > B05CB - Salt solutions
C78275 - Agent Affecting Blood or Body Fluid > C29730 - Electrolyte Replacement Agent
Leavening agent; component of self-raising flour. pH control agent for foods
D019995 - Laboratory Chemicals > D002021 - Buffers > D001639 - Bicarbonates
Same as: D01203
同义名列表
24 个代谢物同义名
Sodium hydrogen carbonic acid; Carbonic acid monosodium salt; Sodium hydrogencarbonic acid; Hydrogen carbonate, sodium; Carbonate monosodium salt; Sodium hydrogen carbonate; Sodium acid carbonic acid; Sodium hydrogencarbonate; Natriumhydrogenkarbonat; Bicarbonic acid OF soda; Sodium bicarbonic acid; Sodium acid carbonate; Bicarbonate, sodium; Bicarbonate OF soda; SodiuM bicarbonate; Soda, baking; Baking soda; NaHCO3; Meylon; e-500; e 500; Neut; e500; Sodium bicarbonate
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:32139
- KEGG: C12603
- PubChem: 516892
- PubChem: 8953
- HMDB: HMDB0303541
- Metlin: METLIN69461
- DrugBank: DB01390
- ChEMBL: CHEMBL1353
- Wikipedia: Sodium_Bicarbonate
- MeSH: Sodium Bicarbonate
- foodb: FDB015419
- chemspider: 8609
- CAS: 144-55-8
- PubChem: 582993
- NIKKAJI: J44.042F
- KNApSAcK: 32139
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Linlin Song, Yongliang Yu, Hongzhi Chen, Yuwei Feng, Shuo Chen, Huihui Zhang, Haijia Zhou, Li Meng, Yue Wang. Response of photosynthetic characteristics and antioxidant system in the leaves of safflower to NaCl and NaHCO3.
Plant cell reports.
2024 May; 43(6):146. doi:
10.1007/s00299-024-03234-7. [PMID: 38764051] - Xiaohong Zhao, Guoning Qi, Jinhong Liu, Kui Chen, Xinxin Miao, Jamshaid Hussain, Shenkui Liu, Huimin Ren. Genome-wide identification of WRKY transcription factors in Casuarina equisetifolia and the function analysis of CeqWRKY11 in response to NaCl/NaHCO3 stresses.
BMC plant biology.
2024 May; 24(1):376. doi:
10.1186/s12870-024-04889-w. [PMID: 38714947] - Wenzheng Lin, Sihan Hu, Ke Li, Yu Shi, Chun Pan, Zhuobin Xu, Dandan Li, Huihui Wang, Bin Li, Hao Chen. Breaking Osteoclast-Acid Vicious Cycle to Rescue Osteoporosis via an Acid Responsive Organic Framework-Based Neutralizing and Gene Editing Platform.
Small (Weinheim an der Bergstrasse, Germany).
2024 May; 20(22):e2307595. doi:
10.1002/smll.202307595. [PMID: 38126648] - Bowei Jia, Hongli Cui, Dajian Zhang, Bingshuang Hu, Yuan Li, Yang Shen, Xiaoxi Cai, Xiaoli Sun, Mingzhe Sun. The conserved evolution of plant H+-ATPase family and the involvement of soybean H+-ATPases in sodium bicarbonate stress responses.
Plant physiology and biochemistry : PPB.
2023 Nov; 204(?):108133. doi:
10.1016/j.plaphy.2023.108133. [PMID: 37883915] - Qiang Li, Minglong Li, Huiying Ma, Man Xue, Tong Chen, Xiaodong Ding, Shuzhen Zhang, Jialei Xiao. Quantitative Phosphoproteomic Analysis Provides Insights into the Sodium Bicarbonate Responsiveness of Glycine max.
Biomolecules.
2023 10; 13(10):. doi:
10.3390/biom13101520. [PMID: 37892202] - Changli Liang, Nali Zhang, Yu Pang, Siyuan Li, Jiafan Shang, Yipeng Zhang, Zhenzhong Kuang, Junhe Liu, Hua Fei. Cultivation of Spirulina platensis for nutrient removal from piggery wastewater.
Environmental science and pollution research international.
2023 Aug; 30(36):85733-85745. doi:
10.1007/s11356-023-28334-x. [PMID: 37392298] - Asif Iqbal, George Nwokocha, Vijay Tiwari, Inderjit K Barphagha, Anne Grove, Jong Hyun Ham, William T Doerrler. A membrane protein of the rice pathogen Burkholderia glumae required for oxalic acid secretion and quorum sensing.
Molecular plant pathology.
2023 Jul; ?(?):. doi:
10.1111/mpp.13376. [PMID: 37428013] - Huili Zhang, Feifei Yu, Peng Xie, Shengyuan Sun, Xinhua Qiao, Sanyuan Tang, Chengxuan Chen, Sen Yang, Cuo Mei, Dekai Yang, Yaorong Wu, Ran Xia, Xu Li, Jun Lu, Yuxi Liu, Xiaowei Xie, Dongmei Ma, Xing Xu, Zhengwei Liang, Zhonghui Feng, Xiahe Huang, Hong Yu, Guifu Liu, Yingchun Wang, Jiayang Li, Qifa Zhang, Chang Chen, Yidan Ouyang, Qi Xie. A Gγ protein regulates alkaline sensitivity in crops.
Science (New York, N.Y.).
2023 03; 379(6638):eade8416. doi:
10.1126/science.ade8416. [PMID: 36952416] - Xing-Bao Tao, Hao Wu. [Effect of lime water processing of Pinelliae Rhizoma Praeparatum on toxic component lectin protein].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2023 Feb; 48(4):951-957. doi:
10.19540/j.cnki.cjcmm.20220718.302. [PMID: 36872265] - Matilde Zaballos, Ignacio Fernández, Arturo Melone, Lucía Rodríguez, Olalla Varela, Sergio García, Oscar Quintela, Elena Vazquez, María José Anadón, Jesús Almendral. Sodium bicarbonate reverts electrophysiologic cardiotoxicity of ropivacaine faster than lipid emulsions in a porcine model.
Basic & clinical pharmacology & toxicology.
2023 Feb; 132(2):211-222. doi:
10.1111/bcpt.13822. [PMID: 36479999] - Pierre Fils Rodrigue Magwell, Kennedy Tchoffo Djoudjeu, Emile Minyaka, Marie-Frédéric Tavea, Oscar Wamba Fotsop, Romeo Fobasso Tagnikeu, Apollin Medueghue Fofou, Chedom Kom Vinnie Darelle, Camille Ulrich Dzokouo Dzoyem, Léopold Gustave Lehman. Sodium Bicarbonate (NaHCO3) Increases Growth, Protein and Photosynthetic Pigments Production and Alters Carbohydrate Production of Spirulina platensis.
Current microbiology.
2023 Jan; 80(2):63. doi:
10.1007/s00284-022-03165-0. [PMID: 36595115] - Adane Yehualaw, Chernet Tafere, Zewdu Yilma, Solomon Abrha. Formulation and In Vitro Evaluation of Furosemide Floating Matrix Tablets Using Boswellia papyrifera Resin as Matrix Forming Polymer.
BioMed research international.
2023; 2023(?):4322375. doi:
10.1155/2023/4322375. [PMID: 37929241] - Tuba Karabey, Şerife Karagözogli, Nisanur Aygün, Zeynep Sümer. The Effect of Oral Care With Black Mulberry Extract on Oral Mucositis, Dry Mouth, and Weight Gain in Patients With Cancer.
Clinical journal of oncology nursing.
2022 11; 26(6):636-642. doi:
10.1188/22.cjon.636-642. [PMID: 36413721] - Heather Walker, Greg D Guthrie, Emilie Lambourg, Philippa Traill, Ian Zealley, Andrew Plumb, Samira Bell. Systematic review and meta-analysis of prophylaxis use with intravenous contrast exposure to prevent contrast-induced nephropathy.
European journal of radiology.
2022 Aug; 153(?):110368. doi:
10.1016/j.ejrad.2022.110368. [PMID: 35636024] - Vandana S Mathur, Elizabeth Li, Donald E Wesson. Effects of veverimer on serum bicarbonate and physical function in diabetic patients with chronic kidney disease and metabolic acidosis: subgroup analysis from a randomized, controlled trial.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2022 06; 37(7):1302-1309. doi:
10.1093/ndt/gfab209. [PMID: 34240198] - Yiğit Kaçar, Ahmet Tarık Baykal, Levent Aydin, Hasan Batmaz. Evaluation of the efficacy of cow colostrum in the treatment and its effect on serum proteomes in calves with cryptosporidiosis.
Veterinary immunology and immunopathology.
2022 Jun; 248(?):110429. doi:
10.1016/j.vetimm.2022.110429. [PMID: 35500421] - Daniel J McCabe, Rachel D Walsh, Peter K Georgakakos, Joshua B Radke, Bryan Z Wilson. Flecainide poisoning and prolongation of elimination due to alkalinization.
The American journal of emergency medicine.
2022 06; 56(?):394.e1-394.e4. doi:
10.1016/j.ajem.2022.03.006. [PMID: 35287973] - Horacio J Adrogué, Ahmed A Awan, Nicolaos E Madias. Determinants of hypokalemia following hypertonic sodium bicarbonate infusion.
Pflugers Archiv : European journal of physiology.
2022 06; 474(6):603-612. doi:
10.1007/s00424-022-02677-9. [PMID: 35275260] - Katarzyna Szczecińska, Małgorzata Wajdlich, Maja Nowicka, Michał Nowicki, Ilona Kurnatowska. Effects of Oral Bicarbonate Supplementation on the Cardiovascular Risk Factors and Serum Nutritional Markers in Non-Dialysed Chronic Kidney Disease Patients.
Medicina (Kaunas, Lithuania).
2022 Apr; 58(4):. doi:
10.3390/medicina58040518. [PMID: 35454357] - Amara Sarwal, Susan Kim, Isaiarasi Gnanasekaran. Life-threatening alkalosis from baking soda pica in an end stage renal disease hemodialysis patient.
Hemodialysis international. International Symposium on Home Hemodialysis.
2022 04; 26(2):E16-E18. doi:
10.1111/hdi.12984. [PMID: 34907640] - Haris Ahmad, Theresa Wertin, Yilin Zhang, Jon O Neher, Beth Auten. Is bicarbonate therapy effective in preventing CKD progression?.
The Journal of family practice.
2022 04; 71(3):E15-E16. doi:
10.12788/jfp.0377. [PMID: 35561240] - Ning Jin, Shouyu Zhang, Shibo Sun, Minghuo Wu, Xiaojing Yang, Jianqiang Xu, Kun Ma, Shui Guan, Weiping Xu. An Organic Solvent-Free Method for the Extraction of Ellagic Acid Compounds from Raspberry Wine Pomace with Assistance of Sodium Bicarbonate.
Molecules (Basel, Switzerland).
2022 Mar; 27(7):. doi:
10.3390/molecules27072145. [PMID: 35408544] - Jason C Siegler, Amelia J Carr, William T Jardine, Lilia Convit, Rebecca Cross, Dale Chapman, Louise M Burke, Megan Ross. The Hyperhydration Potential of Sodium Bicarbonate and Sodium Citrate.
International journal of sport nutrition and exercise metabolism.
2022 03; 32(2):74-81. doi:
10.1123/ijsnem.2021-0179. [PMID: 34875625] - Rachel D Heisler, Jordan J Kelly, Sara Abedinzadegan Abdi, Jennifer L Hawker, Leanne G Fong, Janet L Quon, Josee Z Rioux, Jennifer C Jupp. Evaluation of an oral sodium bicarbonate protocol for high-dose methotrexate urine alkalinization.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2022 Feb; 30(2):1273-1281. doi:
10.1007/s00520-021-06503-3. [PMID: 34471970] - Arman Tsaturyan, Piet Bosshard, Elizaveta Bokova, Olivier Bonny, Kevin Stritt, Beat Roth. The impact of stenting prior to oral chemolysis of upper urinary tract uric acid stones.
International urology and nephrology.
2022 Jan; 54(1):37-45. doi:
10.1007/s11255-021-03072-6. [PMID: 34850328] - Julie Beaume, Lucile Figueres, Mickaël Bobot, Louis de Laforcade, Hamza Ayari, Thibault Dolley-Hitze, Victor Gueutin, Antoine Braconnier, Léonard Golbin, Salvatore Citarda, Guillaume Seret, Lisa Belaïd, Raphaël Cohen, Yosu Luque, Fabrice Larceneux, Riyad N H Seervai, Camille Overs, Jean-Philippe Bertocchio. Sodium Bicarbonate Prescription and Extracellular Volume Increase: Real-world Data Results from the AlcalUN Study.
Clinical pharmacology and therapeutics.
2022 01; 111(1):252-262. doi:
10.1002/cpt.2427. [PMID: 34564842] - Susie Q Lew, Ramin Sam, Antonios H Tzamaloukas, Todd S Ing. A four-stream method for providing variable dialysis fluid bicarbonate concentrations for bicarbonate-based dialysis fluid delivery systems.
Artificial organs.
2021 Dec; 45(12):1576-1581. doi:
10.1111/aor.14083. [PMID: 34637152] - Saban Elitok, Hermann Kuppe, Prasad Devarajan, Rinaldo Bellomo, Berend Isermann, Sabine Westphal, Johanna Kube, Christian Albert, Martin Ernst, Siegfried Kropf, Anja Haase-Fielitz, Michael Haase. Urinary Neutrophil Gelatinase-Associated Lipocalin/Hepcidin-25 Ratio for Early Identification of Patients at Risk for Renal Replacement Therapy After Cardiac Surgery: A Substudy of the BICARBONATE Trial.
Anesthesia and analgesia.
2021 12; 133(6):1510-1519. doi:
10.1213/ane.0000000000005741. [PMID: 34543256] - Shiyi Geng, Emily F Green, Michael C Kurz, Jessica V Rivera. Sodium bicarbonate administration and subsequent potassium concentration in hyperkalemia treatment.
The American journal of emergency medicine.
2021 Dec; 50(?):132-135. doi:
10.1016/j.ajem.2021.07.032. [PMID: 34364111] - Jerry S Liu, Eugene H Fan. Toxic Effects of Flecainide in a Patient With Kidney Failure and Tachyarrhythmia.
JAMA internal medicine.
2021 11; 181(11):1516-1518. doi:
10.1001/jamainternmed.2021.5030. [PMID: 34515729] - Stella I Kourtellidou, Damien R Ashby, Lina R Johansson. Oral sodium bicarbonate in people on haemodialysis: a randomised controlled trial.
BMC nephrology.
2021 10; 22(1):346. doi:
10.1186/s12882-021-02549-x. [PMID: 34674667] - Ahsan Jamal, Muhammad Afzal Rashid, Muhammad Irfan Malik. Effects of sodium bicarbonate and chromium propionate supplementation on growth performance, blood indices of Beetal bucks under heat stress.
Tropical animal health and production.
2021 Oct; 53(5):496. doi:
10.1007/s11250-021-02931-9. [PMID: 34608511] - Paloma Merino-Amador, Patricia González-Donapetry, Mercedes Domínguez-Fernández, Fernando González-Romo, Miguel Ángel Sánchez-Castellano, Alejandro Seoane-Estevez, Alberto Delgado-Iribarren, Julio García, Germán Bou, Manuel Cuenca-Estrella, Jesús Oteo-Iglesias. Clinitest rapid COVID-19 antigen test for the diagnosis of SARS-CoV-2 infection: A multicenter evaluation study.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2021 10; 143(?):104961. doi:
10.1016/j.jcv.2021.104961. [PMID: 34461560] - Elinor C Mannon, Christina L Sartain, Trevin C Wilkes, Jingping Sun, Aaron J Polichnowski, Paul M O'Connor. Renal mass reduction increases the response to exogenous insulin independent of acid-base status or plasma insulin levels in rats.
American journal of physiology. Renal physiology.
2021 10; 321(4):F494-F504. doi:
10.1152/ajprenal.00679.2020. [PMID: 34396787] - Davide Cao, George D Dangas. Sodium Bicarbonate, Contrast-Associated Acute Kidney Injury, and Long-Term Outcomes: The End of an Era?.
Cardiovascular revascularization medicine : including molecular interventions.
2021 10; 31(?):69-70. doi:
10.1016/j.carrev.2021.07.019. [PMID: 34364806] - Fernando Boccalandro, Katherine Shreyder, Laura Harmon, Mandeep Dhindsa, Tallat Fahim, Samia Sheikh. Five-Year Follow-Up of Patients With Radio-Contrast-Induced Acute Renal Injury: Can Intravenous Sodium Bicarbonate Improve Long-Term Outcomes?.
Cardiovascular revascularization medicine : including molecular interventions.
2021 10; 31(?):61-68. doi:
10.1016/j.carrev.2020.11.017. [PMID: 33250404] - Dominique M Bovée, Lodi C W Roksnoer, Cornelis van Kooten, Joris I Rotmans, Liffert Vogt, Martin H de Borst, Robert Zietse, A H Jan Danser, Ewout J Hoorn. Effect of sodium bicarbonate supplementation on the renin-angiotensin system in patients with chronic kidney disease and acidosis: a randomized clinical trial.
Journal of nephrology.
2021 10; 34(5):1737-1745. doi:
10.1007/s40620-020-00944-5. [PMID: 33382448] - Amiya K Barik, Sanjay Agrawal, Priyanka Gupta, Ranjeeta Kumari. Evaluation of equiosmolar 20\% mannitol, 3\% hypertonic saline and 8.4\% sodium bicarbonate on intraoperative brain relaxation and hemodynamic parameters in patients undergoing craniotomy for supratentorial tumors: a prospective randomized study.
Minerva anestesiologica.
2021 09; 87(9):997-1005. doi:
10.23736/s0375-9393.21.15448-3. [PMID: 34612617] - Asif Iqbal, Pradip R Panta, John Ontoy, Jobelle Bruno, Jong Hyun Ham, William T Doerrler. Chemical or Genetic Alteration of Proton Motive Force Results in Loss of Virulence of Burkholderia glumae, the Cause of Rice Bacterial Panicle Blight.
Applied and environmental microbiology.
2021 08; 87(18):e0091521. doi:
10.1128/aem.00915-21. [PMID: 34260305] - Mohamed Sabry Tourky, Ahmed Abdallah Salman, Mohamed Abdalla Salman, Mostafa Mahmoud Abdelfatah, Ahmed E Taha, Hany Hagag, Mohamed Yousef Salah Youssef, Mohamed S Arafa, Sara A Khattab, Marwan Mansour Borham, Ahmed Moustafa. Intraoperative Factors Associated With Early Recipient Death After Adult-to-Adult Living Donor Liver Transplant.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2021 08; 19(8):817-825. doi:
10.6002/ect.2021.0084. [PMID: 34085911] - C Matamoros, J Cai, A D Patterson, K J Harvatine. Comparison of the effects of short-term feeding of sodium acetate and sodium bicarbonate on milk fat production.
Journal of dairy science.
2021 Jul; 104(7):7572-7582. doi:
10.3168/jds.2020-19526. [PMID: 33814140] - Gabriela M Olmedo, Carina G Baigorria, Ana C Ramallo, Milena Sepulveda, Jacqueline Ramallo, Sabrina I Volentini, Viviana A Rapisarda, Luciana Cerioni. Inhibition of the lemon brown rot causal agent Phytophthora citrophthora by low-toxicity compounds.
Journal of the science of food and agriculture.
2021 Jul; 101(9):3613-3619. doi:
10.1002/jsfa.10990. [PMID: 33275277] - Xiaomei Xue, Zhen Liu, Xinde Li, Jie Lu, Can Wang, Xuefeng Wang, Wei Ren, Ruixia Sun, Zhaotong Jia, Xiaopeng Ji, Ying Chen, Yuwei He, Aichang Ji, Wenyan Sun, Hui Zhang, Tony R Merriman, Changgui Li, Lingling Cui. The efficacy and safety of citrate mixture vs sodium bicarbonate on urine alkalization in Chinese primary gout patients with benzbromarone: a prospective, randomized controlled study.
Rheumatology (Oxford, England).
2021 06; 60(6):2661-2671. doi:
10.1093/rheumatology/keaa668. [PMID: 33211886] - Ignacio Torres, Sandrine Poujois, Eliseo Albert, Gabriela Álvarez, Javier Colomina, David Navarro. Point-of-care evaluation of a rapid antigen test (CLINITESTⓇ Rapid COVID-19 Antigen Test) for diagnosis of SARS-CoV-2 infection in symptomatic and asymptomatic individuals.
The Journal of infection.
2021 05; 82(5):e11-e12. doi:
10.1016/j.jinf.2021.02.010. [PMID: 33587922] - Yapeng Fan, Xuke Lu, Xiugui Chen, Junjuan Wang, Delong Wang, Shuai Wang, Lixue Guo, Cun Rui, Yuexin Zhang, Ruifeng Cui, Waqar Afzal Malik, Qinqin Wang, Chao Chen, John Z Yu, Wuwei Ye. Cotton transcriptome analysis reveals novel biological pathways that eliminate reactive oxygen species (ROS) under sodium bicarbonate (NaHCO3) alkaline stress.
Genomics.
2021 05; 113(3):1157-1169. doi:
10.1016/j.ygeno.2021.02.022. [PMID: 33689783] - Silvia Coppola, Alessio Caccioppola, Sara Froio, Davide Chiumello. Sodium Bicarbonate in Different Critically Ill Conditions: From Physiology to Clinical Practice.
Anesthesiology.
2021 05; 134(5):774-783. doi:
10.1097/aln.0000000000003733. [PMID: 33721887] - Chiel Poffé, Felix Wyns, Monique Ramaekers, Peter Hespel. Exogenous Ketosis Impairs 30-min Time-Trial Performance Independent of Bicarbonate Supplementation.
Medicine and science in sports and exercise.
2021 05; 53(5):1068-1078. doi:
10.1249/mss.0000000000002552. [PMID: 33196605] - Simon D Roger, Bruce S Spinowitz, Edgar V Lerma, Steven Fishbane, Stephen R Ash, Julian G Martins, Carol Moreno Quinn, David K Packham. Sodium zirconium cyclosilicate increases serum bicarbonate concentrations among patients with hyperkalaemia: exploratory analyses from three randomized, multi-dose, placebo-controlled trials.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2021 04; 36(5):871-883. doi:
10.1093/ndt/gfaa158. [PMID: 32588050] - Hikaru Morooka, Junichiro Yamamoto, Akihito Tanaka, Daijo Inaguma, Shoichi Maruyama. Relationship between mortality and use of sodium bicarbonate at the time of dialysis initiation: a prospective observational study.
BMC nephrology.
2021 04; 22(1):118. doi:
10.1186/s12882-021-02330-0. [PMID: 33823813] - Lujing Li, Tongyu Tong, Qiao Ji, Zuofeng Xu, Yupeng Guan, Xin Liang, Hai Huang, Yang Kang, Jun Pang. Dual pH- and Glutathione-Responsive CO2-Generating Nanodrug Delivery System for Contrast-Enhanced Ultrasonography and Therapy of Prostate Cancer.
ACS applied materials & interfaces.
2021 Mar; 13(11):12899-12911. doi:
10.1021/acsami.1c00077. [PMID: 33720701] - Amber B Clemmons, Aaron Chase, Phung Duong, Jennifer L Waller, Katherine Saunders, Locke Bryan. Assessing the impact of adding acetazolamide to oral or intravenous sodium bicarbonate as compared with intravenous bicarbonate monotherapy as urinary alkalinization in adults receiving high-dose methotrexate.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2021 Mar; 29(3):1527-1534. doi:
10.1007/s00520-020-05646-z. [PMID: 32725375] - Alicia Mastrocco, Alex L Blutinger, Samantha A Baine, Jennifer E Prittie. Use of injectable lipid emulsion and sodium bicarbonate to treat severe cardiovascular collapse secondary to lamotrigine toxicosis in a dog.
Journal of the American Veterinary Medical Association.
2021 Mar; 258(5):510-514. doi:
10.2460/javma.258.5.510. [PMID: 33620240] - Ranjeeta Chand, Erik R Swenson, David S Goldfarb. Sodium bicarbonate therapy for acute respiratory acidosis.
Current opinion in nephrology and hypertension.
2021 03; 30(2):223-230. doi:
10.1097/mnh.0000000000000687. [PMID: 33395037] - Eliot Shevel. Conditions Favoring Increased COVID-19 Morbidity and Mortality: Their Common Denominator and its Early Treatment.
Missouri medicine.
2021 Mar; 118(2):113-115. doi:
NULL. [PMID: 33840847] - Louis de Laforcade, Mickaël Bobot, Marie-France Bellin, Olivier Clément, Steven Grangé, Nicolas Grenier, Alain Wynckel, Dominique Guerrot. Kidney and contrast media: Common viewpoint of the French Nephrology societies (SFNDT, FIRN, CJN) and the French Radiological Society (SFR) following ESUR guidelines.
Diagnostic and interventional imaging.
2021 Mar; 102(3):131-139. doi:
10.1016/j.diii.2021.01.007. [PMID: 33531265] - Jipeng Chen, Xiaoxiao Li, Xiaoxue Ye, Peng Guo, Zhubing Hu, Guoning Qi, Fuqiang Cui, Shenkui Liu. An S-ribonuclease binding protein EBS1 and brassinolide signaling are specifically required for Arabidopsis tolerance to bicarbonate.
Journal of experimental botany.
2021 02; 72(4):1449-1459. doi:
10.1093/jxb/eraa524. [PMID: 33165537] - Simon R Bailey, Grace Forbes, Naomi Selvadurai, Katelin McLarney, Susan Jones, Catherine M Steel. The effect of serial administration of bicarbonate on plasma total CO2 concentrations in horses.
Drug testing and analysis.
2021 Feb; 13(2):397-403. doi:
10.1002/dta.2937. [PMID: 33161618] - Elizabeth Kramer, Michael Filtz, Makala Pace. Evaluation of methotrexate clearance with an enteral urine alkalinization protocol for patients receiving high-dose methotrexate.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2021 Jan; 27(1):26-32. doi:
10.1177/1078155220908946. [PMID: 32164493] - Bianca N Quade, Mark D Parker, Rossana Occhipinti. The therapeutic importance of acid-base balance.
Biochemical pharmacology.
2021 01; 183(?):114278. doi:
10.1016/j.bcp.2020.114278. [PMID: 33039418] - Siri Shastry, Judson Ellis, George Loo, Rajesh Vedanthan, Lynne D Richardson, Alex F Manini. Antidotal Sodium Bicarbonate Therapy: Delayed QTc Prolongation and Cardiovascular Events.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2021 01; 17(1):27-36. doi:
10.1007/s13181-020-00799-z. [PMID: 32737857] - Mark Diachinsky, Tracey Tran, Jennifer Jupp, Krista McKinnon. Oral sodium bicarbonate protocol for high-dose methotrexate urine alkalinization: A pediatric experience.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2021 Jan; 27(1):119-127. doi:
10.1177/1078155220915769. [PMID: 32316877] - Byron C Drumheller, Erin E Sabolick. Hemodynamic Instability and Abnormal Vasopressor Responsiveness in the Setting of Severe Metabolic Acidosis Treated With Adapted Alkalinization and Continuous Renal Replacement Therapy in the Emergency Department.
The Journal of emergency medicine.
2021 Jan; 60(1):67-72. doi:
10.1016/j.jemermed.2020.09.022. [PMID: 33875156] - D R Wood, R M Blome, L C Ribeiro, A J Keunen, B W Keunen, G W Smith, D L Renaud. Short communication: Effects of different blood buffers administered in electrolyte solution to grain-fed veal calves experiencing diarrhea.
Journal of dairy science.
2021 Jan; 104(1):957-962. doi:
10.3168/jds.2020-18526. [PMID: 33189262] - Heeseop Shin, Saeed Taghavifar, Sana Salehi, Peter Joyce, Ali Gholamrezanezhad. Current comments on contrast media administration in patients with renal insufficiency.
Clinical imaging.
2021 Jan; 69(?):37-44. doi:
10.1016/j.clinimag.2020.06.040. [PMID: 32652456] - Florian M Trefz, Ingrid Lorenz, Peter D Constable. Dependence of the apparent bicarbonate space on initial plasma bicarbonate concentration and carbon dioxide tension in neonatal calves with diarrhea, acidemia, and metabolic acidosis.
Journal of veterinary internal medicine.
2021 Jan; 35(1):644-654. doi:
10.1111/jvim.16031. [PMID: 33452736] - Karl Sebastian Johansson, Lotte Christine Groth Høgberg, Mikkel Bring Christensen, Tonny Studsgaard Petersen, Kim Dalhoff, Søren Bøgevig. [Local anaesthetic systemic toxicity].
Ugeskrift for laeger.
2020 12; 182(51):. doi:
". [PMID: 33317687] - Elinor C Mannon, Paul M O'Connor. Alkali supplementation as a therapeutic in chronic kidney disease: what mediates protection?.
American journal of physiology. Renal physiology.
2020 12; 319(6):F1090-F1104. doi:
10.1152/ajprenal.00343.2020. [PMID: 33166183] - Orly F Kohn. In older adults with CKD and mild acidosis, oral sodium bicarbonate did not improve physical function.
Annals of internal medicine.
2020 11; 173(10):JC56. doi:
10.7326/acpj202011170-056. [PMID: 33197344] - Si-Jun Wu, Ping Qiu, Pian Li, Zheng Li, Wen-Long Li. A near-infrared spectroscopy-based end-point determination method for the blending process of Dahuang soda tablets.
Journal of Zhejiang University. Science. B.
2020 Nov; 21(11):897-910. doi:
10.1631/jzus.b2000417. [PMID: 33150773] - Alexander Morales, John Danziger. Management Consideration in Drug-Induced Lactic Acidosis.
Clinical journal of the American Society of Nephrology : CJASN.
2020 10; 15(10):1511-1512. doi:
10.2215/cjn.14781219. [PMID: 32444396] - Huihui Zhang, Yuze Huo, Zisong Xu, Kaiwen Guo, Yue Wang, Xiaosong Zhang, Nan Xu, Guangyu Sun. Physiological and proteomics responses of nitrogen assimilation and glutamine/glutamine family of amino acids metabolism in mulberry (Morus alba L.) leaves to NaCl and NaHCO3 stress.
Plant signaling & behavior.
2020 10; 15(10):1798108. doi:
10.1080/15592324.2020.1798108. [PMID: 32729371] - Mehmet Giray Sönmez, Gökhan Ecer, Ahmet Atici, Mehmet Serkan Özkent, Mehmet Sinan İyisoy, Ahmet Öztürk. Comparison of Oral Sodium Bicarbonate and Solifenacin Treatment in Female Overactive Bladder Patients With Acidic Urine pH.
Female pelvic medicine & reconstructive surgery.
2020 10; 26(10):649-653. doi:
10.1097/spv.0000000000000642. [PMID: 30335650] - Xin Wang, Zainab Ajab, Chenxi Liu, Songmiao Hu, Jiali Liu, Qingjie Guan. Overexpression of transcription factor SlWRKY28 improved the tolerance of Populus davidiana × P. bolleana to alkaline salt stress.
BMC genetics.
2020 09; 21(1):103. doi:
10.1186/s12863-020-00904-9. [PMID: 32928116] - Reo Hamaguchi, Takashi Ito, Ryoko Narui, Hiromasa Morikawa, Shinji Uemoto, Hiromi Wada. Effects of Alkalization Therapy on Chemotherapy Outcomes in Advanced Pancreatic Cancer: A Retrospective Case-Control Study.
In vivo (Athens, Greece).
2020 Sep; 34(5):2623-2629. doi:
10.21873/invivo.12080. [PMID: 32871792] - M G H Betjes. [A requiem for prehydration in CT imaging?].
Nederlands tijdschrift voor geneeskunde.
2020 07; 164(?):. doi:
NULL. [PMID: 32779931] - Neesh Pannu. In patients with CKD having CT with contrast media, no prehydration and prehydration did not differ for AKI.
Annals of internal medicine.
2020 07; 173(2):JC8. doi:
10.7326/acpj202007210-009. [PMID: 32687762] - Richard Solomon. Hydration: Intravenous and Oral: Approaches, Principals, and Differing Regimens: Is It What Goes in or What Comes Out That Is Important?.
Interventional cardiology clinics.
2020 07; 9(3):385-393. doi:
10.1016/j.iccl.2020.02.009. [PMID: 32471678] - Miles D Witham, Margaret Band, Huey Chong, Peter T Donnan, Geeta Hampson, May Khei Hu, Roberta Littleford, Edmund Lamb, Philip A Kalra, Gwen Kennedy, Paul McNamee, Deirdre Plews, Petra Rauchhaus, Roy L Soiza, Deepa Sumukadas, Graham Warwick, Alison Avenell. Sodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease: the BiCARB RCT.
Health technology assessment (Winchester, England).
2020 06; 24(27):1-90. doi:
10.3310/hta24270. [PMID: 32568065] - Fernando Caravaca-Fontán, Rosa Díaz-Campillejo, Julián Valladares, Cristina López Arnaldo, Sergio Barroso, Enrique Luna, Francisco Caravaca. Successful correction of metabolic acidosis is difficult to achieve in chronic kidney disease.
Nefrologia.
2020 May; 40(3):328-335. doi:
10.1016/j.nefro.2019.09.006. [PMID: 31862183] - J Zeeh. Title Not Available.
MMW Fortschritte der Medizin.
2020 05; 162(9):28. doi:
10.1007/s15006-020-0465-0. [PMID: 32405851] - Kayla P Neiderfer, Amanda M Barnard, Kassandra Z Moyer, Alexis M Trench, Ashley E Taylor, Shane K Cronin, Tanya F Gressley. Effects of calcium carbonate, magnesium oxide and encapsulated sodium bicarbonate on measures of post-ruminal fermentation.
Journal of animal physiology and animal nutrition.
2020 May; 104(3):802-811. doi:
10.1111/jpn.13331. [PMID: 32083351] - Mona R Rudnick, Gregory J Blair, Ware G Kuschner, Juliana Barr. Lactic Acidosis and the Role of Sodium Bicarbonate: A Narrative Opinion.
Shock (Augusta, Ga.).
2020 05; 53(5):528-536. doi:
10.1097/shk.0000000000001415. [PMID: 31318832] - Joseph Walker Keach, Maggie A Stanislawski, Anna E Barón, Mary E Plomondon, Paula Langner, Amit Amin, Heather M Gilmartin, Stephen Waldo, Thomas M Maddox. Variation in contrast-associated acute kidney injury prophylaxis for percutaneous coronary intervention: insights from the Veterans Affairs Clinical Assessment, Reporting, and Tracking (CART) program.
BMC nephrology.
2020 04; 21(1):150. doi:
10.1186/s12882-020-01802-z. [PMID: 32345254] - Michiaki Abe, Tetsuya Akaishi, Mutsumi Shoji, Takuhiro Yamaguchi, Takashi Miki, Fumitoshi Satoh, Shin Takayama, Satomi Yamasaki, Kazuhiko Kawaguchi, Hiroshi Sato, Tadashi Ishii, Sadayoshi Ito. Reno-protective effects of oral alkalizing agents in chronic kidney disease with aciduria: protocol for a randomized cohort study.
BMC nephrology.
2020 04; 21(1):144. doi:
10.1186/s12882-020-01807-8. [PMID: 32321450] - Zhang Huihui, Li Xin, Guan Yupeng, Li Mabo, Wang Yue, An Meijun, Zhang Yuehui, Liu Guanjun, Xu Nan, Sun Guangyu. Physiological and proteomic responses of reactive oxygen species metabolism and antioxidant machinery in mulberry (Morus alba L.) seedling leaves to NaCl and NaHCO3 stress.
Ecotoxicology and environmental safety.
2020 Apr; 193(?):110259. doi:
10.1016/j.ecoenv.2020.110259. [PMID: 32097787] - NULL. Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis (BiCARB): a pragmatic randomised, double-blind, placebo-controlled trial.
BMC medicine.
2020 04; 18(1):91. doi:
10.1186/s12916-020-01542-9. [PMID: 32268897] - A R Ahmed. Should Oral Sodium Bicarbonate Be Used to Prevent Chronic Kidney Disease Progression?.
Irish medical journal.
2020 04; 113(4):65. doi:
NULL. [PMID: 32268058] - Rubén Pampín, Yoar Labeaga, Belén Rodríguez, Beatriz Fernández, Rubén Fernández, Mónica Carbajales. Experience with ambulatory high-dose methotrexate administration as CNS prophylaxis in patients with non-Hodgkin lymphoma.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2020 Apr; 26(3):549-555. doi:
10.1177/1078155219852412. [PMID: 31156052] - Rohit J Timal, Judith Kooiman, Yvo W J Sijpkens, Jean-Paul P M de Vries, Iris J A M Verberk-Jonkers, Harald F H Brulez, Marjolijn van Buren, Aart J van der Molen, Suzanne C Cannegieter, Hein Putter, Wilbert B van den Hout, J Wouter Jukema, Ton J Rabelink, Menno V Huisman. Effect of No Prehydration vs Sodium Bicarbonate Prehydration Prior to Contrast-Enhanced Computed Tomography in the Prevention of Postcontrast Acute Kidney Injury in Adults With Chronic Kidney Disease: The Kompas Randomized Clinical Trial.
JAMA internal medicine.
2020 04; 180(4):533-541. doi:
10.1001/jamainternmed.2019.7428. [PMID: 32065601] - Hiroshi Yonekura, Yohei Kawasaki, Yuki Nakamori, Masataka Kamei. The Use of Sodium Bicarbonate for Metabolic Acidosis in Patients With Acute Kidney Injury.
Critical care medicine.
2020 03; 48(3):e251-e252. doi:
10.1097/ccm.0000000000004111. [PMID: 32058392] - Zhang Huihui, Wang Yue, Li Xin, He Guoqiang, Che Yanhui, Teng Zhiyuan, Shao Jieyu, Xu Nan, Sun Guangyu. Chlorophyll synthesis and the photoprotective mechanism in leaves of mulberry (Morus alba L.) seedlings under NaCl and NaHCO3 stress revealed by TMT-based proteomics analyses.
Ecotoxicology and environmental safety.
2020 Mar; 190(?):110164. doi:
10.1016/j.ecoenv.2020.110164. [PMID: 31927191] - Lui G Forni, Luke E Hodgson, Nicholas M Selby. The Janus faces of bicarbonate therapy in the ICU: not sure!.
Intensive care medicine.
2020 03; 46(3):522-524. doi:
10.1007/s00134-019-05885-7. [PMID: 31820031] - Zhongheng Zhang. The author replies.
Critical care medicine.
2020 03; 48(3):e252. doi:
10.1097/ccm.0000000000004148. [PMID: 32058393] - Kalani L Raphael, Tom Greene, Guo Wei, Tristin Bullshoe, Kunani Tuttle, Alfred K Cheung, Srinivasan Beddhu. Sodium Bicarbonate Supplementation and Urinary TGF-β1 in Nonacidotic Diabetic Kidney Disease: A Randomized, Controlled Trial.
Clinical journal of the American Society of Nephrology : CJASN.
2020 02; 15(2):200-208. doi:
10.2215/cjn.06600619. [PMID: 31974286] - Wei-Yu Li, Cheng Wang, Heng-Hua Shi, Bo Wang, Jing-Xuan Wang, Yu-Shu Liu, Jing-Yu Ma, Sen-Ya Tian, Yao-Wen Zhang. Genome-wide analysis of ethylene-response factor family in adzuki bean and functional determination of VaERF3 under saline-alkaline stress.
Plant physiology and biochemistry : PPB.
2020 Feb; 147(?):215-222. doi:
10.1016/j.plaphy.2019.12.019. [PMID: 31869734] - Chirag R Parikh, Caroline Liu, Maria K Mor, Paul M Palevsky, James S Kaufman, Heather Thiessen Philbrook, Steven D Weisbord. Kidney Biomarkers of Injury and Repair as Predictors of Contrast-Associated AKI: A Substudy of the PRESERVE Trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2020 02; 75(2):187-194. doi:
10.1053/j.ajkd.2019.06.011. [PMID: 31547939] - Reo Hamaguchi, Ryoko Narui, Hiromi Wada. Effects of Alkalization Therapy on Chemotherapy Outcomes in Metastatic or Recurrent Pancreatic Cancer.
Anticancer research.
2020 Feb; 40(2):873-880. doi:
10.21873/anticanres.14020. [PMID: 32014931] - G Chen, D Wu, M X Li. [The 475th case: renal tubular acidosis, renal failure, anemia, and lactic acidosis].
Zhonghua nei ke za zhi.
2020 Feb; 59(2):165-168. doi:
10.3760/cma.j.issn.0578-1426.2020.02.015. [PMID: 32074694] - Michal L Melamed, Edward J Horwitz, Mirela A Dobre, Matthew K Abramowitz, Liping Zhang, Yungtai Lo, William E Mitch, Thomas H Hostetter. Effects of Sodium Bicarbonate in CKD Stages 3 and 4: A Randomized, Placebo-Controlled, Multicenter Clinical Trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2020 02; 75(2):225-234. doi:
10.1053/j.ajkd.2019.07.016. [PMID: 31699517]