stigmatellin (BioDeep_00000009125)

   


代谢物信息卡片


Stigmatellin A

化学式: C30H42O7 (514.293)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC=C(C)C=CC=CC(C(C)C(C(C)CCC1=C(C(=O)C2=C(O1)C(=C(C=C2OC)OC)O)C)OC)OC
InChI: InChI=1S/C30H42O7/c1-10-18(2)13-11-12-14-22(33-6)21(5)29(36-9)19(3)15-16-23-20(4)27(31)26-24(34-7)17-25(35-8)28(32)30(26)37-23/h10-14,17,19,21-22,29,32H,15-16H2,1-9H3/b13-11+,14-12+,18-10+/t19-,21+,22-,29-/m0/s1

描述信息

A member of the class of chromones that is isolated from Stigmatella aurantiaca Sg a15.
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents

同义名列表

3 个代谢物同义名

Stigmatellin A; stigmatellin; Stigmatellin A



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADAM17, BCL2, CRYZ, ETHE1, MAPK8, PRKX, TNK1, VDR, XDH
Peripheral membrane protein 4 FKBP2, HSD17B6, NDUFA5, TNK1
Endoplasmic reticulum membrane 2 BCL2, FKBP2
Nucleus 6 BCL2, CYC1, ETHE1, MAPK8, PRKX, VDR
cytosol 7 ADAM17, BCL2, CRYZ, MAPK8, NGB, VDR, XDH
nucleoplasm 5 CD2, ETHE1, MAPK8, PRKX, VDR
RNA polymerase II transcription regulator complex 1 VDR
Cell membrane 2 ADAM17, CD2
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 MT-CYB
Synapse 1 MAPK8
cell surface 3 ADAM17, CD2, HBEGF
Golgi apparatus 1 CD2
Golgi membrane 1 ADAM17
mitochondrial inner membrane 4 CYC1, MT-CYB, NDUFA5, SQOR
Cytoplasm, cytosol 1 NGB
plasma membrane 4 ADAM17, CD2, HBEGF, TNK1
Membrane 6 ADAM17, BCL2, CYC1, FKBP2, MT-CYB, TNK1
apical plasma membrane 1 ADAM17
axon 1 MAPK8
extracellular exosome 2 CRYZ, SOD2
Lumenal side 1 HSD17B6
endoplasmic reticulum 3 BCL2, FKBP2, HSD17B6
extracellular space 3 HBEGF, TST, XDH
mitochondrion 9 BCL2, CRYZ, CYC1, ETHE1, MT-CYB, NDUFA5, SOD2, SQOR, TST
protein-containing complex 2 BCL2, CD2
intracellular membrane-bounded organelle 1 HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 2 ADAM17, CD2
extracellular region 2 CD2, HBEGF
cytoplasmic side of plasma membrane 1 CD2
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, CYC1
mitochondrial outer membrane 1 BCL2
Mitochondrion matrix 4 ETHE1, NGB, SOD2, TST
mitochondrial matrix 4 ETHE1, NGB, SOD2, TST
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 CD2
actin cytoskeleton 1 ADAM17
cell-cell junction 1 CD2
Mitochondrion inner membrane 3 CYC1, MT-CYB, NDUFA5
Matrix side 1 NDUFA5
Membrane raft 1 ADAM17
pore complex 1 BCL2
mitochondrial nucleoid 1 SOD2
Peroxisome 1 XDH
sarcoplasmic reticulum 1 XDH
receptor complex 1 VDR
chromatin 1 VDR
myelin sheath 1 BCL2
respiratory chain complex I 1 NDUFA5
endoplasmic reticulum lumen 1 ADAM17
endocytic vesicle membrane 1 HBEGF
clathrin-coated endocytic vesicle membrane 1 HBEGF
respiratory chain complex III 2 CYC1, MT-CYB
basal dendrite 1 MAPK8
BAD-BCL-2 complex 1 BCL2


文献列表

  • Marco Consiglio, Marta Viano, Stefania Casarin, Carlotta Castagnoli, Gianpiero Pescarmona, Francesca Silvagno. Mitochondrial and lipogenic effects of vitamin D on differentiating and proliferating human keratinocytes. Experimental dermatology. 2015 Oct; 24(10):748-53. doi: 10.1111/exd.12761. [PMID: 26010336]
  • Yuan-Ting Hsu, Tse-Min Lee. Modulation of gene expression of carotene biosynthesis-related protein by photosynthetic electron transport for the acclimation of intertidal macroalga Ulva fasciata to hypersalinity and excess light. Physiologia plantarum. 2012 Mar; 144(3):225-37. doi: 10.1111/j.1399-3054.2011.01547.x. [PMID: 22122736]
  • Edward A Berry, Li-Shar Huang, Dong-Woo Lee, Fevzi Daldal, Kazuo Nagai, Nobuko Minagawa. Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex. Biochimica et biophysica acta. 2010 Mar; 1797(3):360-70. doi: 10.1016/j.bbabio.2009.12.003. [PMID: 20025846]
  • Patrick J Crowley, Edward A Berry, Thomas Cromartie, Fevzi Daldal, Christopher R A Godfrey, Dong-Woo Lee, Janet E Phillips, Anne Taylor, Russell Viner. The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D. Bioorganic & medicinal chemistry. 2008 Dec; 16(24):10345-55. doi: 10.1016/j.bmc.2008.10.030. [PMID: 18996700]
  • Lothar Esser, Maria Elberry, Fei Zhou, Chang-An Yu, Linda Yu, Di Xia. Inhibitor-complexed structures of the cytochrome bc1 from the photosynthetic bacterium Rhodobacter sphaeroides. The Journal of biological chemistry. 2008 Feb; 283(5):2846-57. doi: 10.1074/jbc.m708608200. [PMID: 18039651]
  • E Yamashita, H Zhang, W A Cramer. Structure of the cytochrome b6f complex: quinone analogue inhibitors as ligands of heme cn. Journal of molecular biology. 2007 Jun; 370(1):39-52. doi: 10.1016/j.jmb.2007.04.011. [PMID: 17498743]
  • Jason W Cooley, Tomoko Ohnishi, Fevzi Daldal. Binding dynamics at the quinone reduction (Qi) site influence the equilibrium interactions of the iron sulfur protein and hydroquinone oxidation (Qo) site of the cytochrome bc1 complex. Biochemistry. 2005 Aug; 44(31):10520-32. doi: 10.1021/bi050571+. [PMID: 16060661]
  • Jiusheng Yan, William A Cramer. Molecular control of a bimodal distribution of quinone-analogue inhibitor binding sites in the cytochrome b(6)f complex. Journal of molecular biology. 2004 Nov; 344(2):481-93. doi: 10.1016/j.jmb.2004.09.053. [PMID: 15522300]
  • Jason W Cooley, Arthur G Roberts, Michael K Bowman, David M Kramer, Fevzi Daldal. The raised midpoint potential of the [2Fe2S] cluster of cytochrome bc1 is mediated by both the Qo site occupants and the head domain position of the Fe-S protein subunit. Biochemistry. 2004 Mar; 43(8):2217-27. doi: 10.1021/bi035938u. [PMID: 14979718]
  • Genji Kurisu, Huamin Zhang, Janet L Smith, William A Cramer. Structure of the cytochrome b6f complex of oxygenic photosynthesis: tuning the cavity. Science (New York, N.Y.). 2003 Nov; 302(5647):1009-14. doi: 10.1126/science.1090165. [PMID: 14526088]
  • Vitaly D Samuilov, Elena M Lagunova, Dmitry B Kiselevsky, Elena V Dzyubinskaya, Yana V Makarova, Mikhail V Gusev. Participation of chloroplasts in plant apoptosis. Bioscience reports. 2003 Apr; 23(2-3):103-17. doi: 10.1023/a:1025576307912. [PMID: 14570380]
  • A R Crofts, B Barquera, R B Gennis, R Kuras, M Guergova-Kuras, E A Berry. Mechanism of ubiquinol oxidation by the bc(1) complex: different domains of the quinol binding pocket and their role in the mechanism and binding of inhibitors. Biochemistry. 1999 Nov; 38(48):15807-26. doi: 10.1021/bi990962m. [PMID: 10625446]
  • E Darrouzet, M Valkova-Valchanova, T Ohnishi, F Daldal. Structure and function of the bacterial bc1 complex: domain movement, subunit interactions, and emerging rationale engineering attempts. Journal of bioenergetics and biomembranes. 1999 Jun; 31(3):275-88. doi: 10.1023/a:1005428014548. [PMID: 10591533]