Pikromycin (BioDeep_00000009028)

   

natural product


代谢物信息卡片


Albomycetin

化学式: C28H47NO8 (525.3302)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 35.59%

分子结构信息

SMILES: CCC1C(C=CC(=O)C(CC(C(C(C(=O)C(C(=O)O1)C)C)OC2C(C(CC(O2)C)N(C)C)O)C)C)(C)O
InChI: InChI=1S/C28H47NO8/c1-10-22-28(7,34)12-11-21(30)15(2)13-16(3)25(18(5)23(31)19(6)26(33)36-22)37-27-24(32)20(29(8)9)14-17(4)35-27/h11-12,15-20,22,24-25,27,32,34H,10,13-14H2,1-9H3/b12-11+/t15-,16+,17-,18+,19-,20+,22-,24-,25+,27+,28+/m1/s1

描述信息

A macrolide antibiotic that is biosynthesised by Streptomyces venezuelae.

同义名列表

3 个代谢物同义名

Pikromycin; Albomycetin; Pikromycin



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ACP6, CPOX, FASN, MMUT, PICK1
Golgi apparatus, trans-Golgi network membrane 1 ATP2C1
Peripheral membrane protein 3 CYP1B1, MBP, PICK1
Endoplasmic reticulum membrane 3 CYP1B1, SLC33A1, SPCS2
Nucleus 2 ANKRD42, MBP
cytosol 5 ACP5, CPOX, FASN, MBP, PICK1
trans-Golgi network 1 ATP2C1
Cell membrane 1 AGTR2
Lipid-anchor 1 PICK1
Cytoplasmic side 1 MBP
Multi-pass membrane protein 4 AGTR2, ATP2C1, SLC33A1, SPCS2
Synapse 2 MBP, PICK1
cell surface 1 MBP
Golgi apparatus 3 ATP2C1, FASN, PICK1
Golgi membrane 2 ATP2C1, SLC33A1
neuronal cell body 1 MBP
presynaptic membrane 1 PICK1
synaptic vesicle 1 PICK1
Lysosome 1 ACP5
plasma membrane 7 AGTR2, ATP2C1, FASN, MBP, MUC5AC, PICK1, SLC33A1
Membrane 8 ACP5, ATP2C1, CPOX, CYP1B1, FASN, PICK1, RSL1D1, SLC33A1
extracellular exosome 4 FASN, LYZ, MBP, MUC5AC
endoplasmic reticulum 1 ATP2C1
extracellular space 2 LYZ, MUC5AC
perinuclear region of cytoplasm 1 PICK1
mitochondrion 4 ACP6, CPOX, CYP1B1, MMUT
protein-containing complex 1 MBP
intracellular membrane-bounded organelle 2 CYP1B1, PICK1
Microsome membrane 1 CYP1B1
postsynaptic density 1 PICK1
Secreted 1 MUC5AC
extracellular region 3 LYZ, MBP, MUC5AC
Mitochondrion matrix 1 MMUT
mitochondrial matrix 2 ACP6, MMUT
nucleolus 1 RSL1D1
Cytoplasm, perinuclear region 1 PICK1
Cytoplasm, cytoskeleton 1 PICK1
extracellular matrix 1 MUC5AC
mitochondrial intermembrane space 1 CPOX
collagen-containing extracellular matrix 1 MBP
neuron projection 1 PICK1
cell periphery 1 MBP
Chromosome 1 RSL1D1
cytoskeleton 1 PICK1
[Isoform 3]: Nucleus 1 MBP
Nucleus, nucleolus 1 RSL1D1
Melanosome 1 FASN
Golgi cisterna membrane 1 ATP2C1
myelin sheath 1 MBP
trans-Golgi network membrane 1 PICK1
ficolin-1-rich granule lumen 1 MBP
Golgi lumen 1 MUC5AC
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
endocytic vesicle membrane 1 PICK1
transport vesicle 1 MBP
azurophil granule lumen 1 LYZ
Golgi apparatus, Golgi stack membrane 1 ATP2C1
ribonucleoprotein complex 1 RSL1D1
Synapse, synaptosome 1 PICK1
cis-Golgi network membrane 1 ATP2C1
mucus layer 1 MUC5AC
compact myelin 1 MBP
internode region of axon 1 MBP
[Bone marrow proteoglycan]: Secreted 1 MBP
postsynaptic early endosome 1 PICK1
glycogen granule 1 FASN
Myelin membrane 1 MBP
signal peptidase complex 1 SPCS2


文献列表

  • David L Akey, Jeffrey D Kittendorf, John W Giraldes, Robert A Fecik, David H Sherman, Janet L Smith. Structural basis for macrolactonization by the pikromycin thioesterase. Nature chemical biology. 2006 Oct; 2(10):537-42. doi: 10.1038/nchembio824. [PMID: 16969372]