SB-200646 (BioDeep_00000008839)

 

Secondary id: BioDeep_00001883857


代谢物信息卡片


N-(1-Methyl-5-indolyl)-N-(3-pyridyl)urea

化学式: C15H14N4O (266.1168)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1C=CC2=C1C=CC(=C2)NC(=O)NC3=CN=CC=C3
InChI: InChI=1S/C15H14N4O/c1-19-8-6-11-9-12(4-5-14(11)19)17-15(20)18-13-3-2-7-16-10-13/h2-10H,1H3,(H2,17,18,20)

描述信息

同义名列表

4 个代谢物同义名

N-(1-Methyl-5-indolyl)-N-(3-pyridyl)urea; SB-200646; SB 200646; SB 200646



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ADRA1A, GUCY1A1, HTR2B, ITPR3, S100A12
Peripheral membrane protein 2 ACHE, S100A12
Endoplasmic reticulum membrane 2 DRD1, ITPR3
Mitochondrion membrane 1 MAOA
Nucleus 4 ACHE, ADRA1A, DRD1, S100A12
cytosol 4 ADRA1A, GUCY1A1, MAOA, S100A12
dendrite 7 DRD2, HTR1A, HTR1D, HTR2A, HTR2B, HTR2C, HTR6
nucleoplasm 3 ADRA1A, HTR2B, ITPR3
Cell membrane 13 ACHE, ADRA1A, DRD1, DRD2, GPRC5A, HTR1A, HTR1D, HTR2A, HTR2B, HTR2C, HTR3A, HTR6, S100A12
Cytoplasmic side 1 MAOA
Cleavage furrow 1 HTR3A
Cell projection, axon 1 HTR2A
Multi-pass membrane protein 13 ADRA1A, CACNA1I, DRD1, DRD2, GPRC5A, HTR1A, HTR1D, HTR2A, HTR2B, HTR2C, HTR3A, HTR6, ITPR3
Golgi apparatus membrane 1 DRD2
Synapse 8 ACHE, DRD2, HTR1A, HTR1D, HTR2B, HTR2C, HTR3A, HTR6
cell surface 1 ACHE
dendritic shaft 1 HTR2A
glutamatergic synapse 4 DRD1, DRD2, GUCY1A1, HTR2A
Golgi apparatus 1 ACHE
Golgi membrane 1 DRD2
neuromuscular junction 1 ACHE
neuronal cell body 2 HTR2A, ITPR3
postsynapse 1 HTR3A
presynaptic membrane 3 DRD1, DRD2, HTR2A
Cytoplasmic vesicle, secretory vesicle 1 NTS
Presynapse 1 HTR2A
acrosomal vesicle 1 DRD2
plasma membrane 15 ACHE, ADRA1A, CACNA1I, DRD1, DRD2, GPRC5A, HTR1A, HTR1D, HTR2A, HTR2B, HTR2C, HTR3A, HTR6, ITPR3, S100A12
synaptic vesicle membrane 1 DRD2
Membrane 5 ACHE, CACNA1I, HTR3A, ITPR3, MAOA
axon 2 DRD2, HTR2A
brush border 1 ITPR3
caveola 2 ADRA1A, HTR2A
extracellular exosome 1 GPRC5A
endoplasmic reticulum 1 ITPR3
extracellular space 1 ACHE
perinuclear region of cytoplasm 1 ACHE
mitochondrion 1 MAOA
intracellular membrane-bounded organelle 3 ADRA1A, GPRC5A, NTS
Secreted 3 ACHE, NTS, S100A12
extracellular region 3 ACHE, NTS, S100A12
Mitochondrion outer membrane 1 MAOA
Single-pass membrane protein 1 MAOA
mitochondrial outer membrane 1 MAOA
Extracellular side 1 ACHE
ciliary membrane 2 DRD1, DRD2
Nucleus membrane 1 ADRA1A
nuclear membrane 1 ADRA1A
dendritic spine 2 DRD1, DRD2
perikaryon 1 DRD2
cytoplasmic vesicle 1 HTR2A
nucleolus 2 GPRC5A, ITPR3
apical part of cell 1 ITPR3
vesicle 1 GPRC5A
postsynaptic membrane 4 DRD1, DRD2, HTR2A, HTR3A
Cytoplasm, cytoskeleton 1 S100A12
GABA-ergic synapse 3 DRD1, DRD2, GUCY1A1
basement membrane 1 ACHE
sarcoplasmic reticulum 1 ITPR3
Cell projection, dendritic spine 1 DRD1
lateral plasma membrane 1 DRD2
nuclear outer membrane 1 ITPR3
Postsynaptic cell membrane 1 HTR3A
receptor complex 2 GPRC5A, ITPR3
neuron projection 1 HTR3A
cilium 3 DRD1, DRD2, HTR6
cytoskeleton 1 S100A12
non-motile cilium 2 DRD1, DRD2
serotonin-activated cation-selective channel complex 1 HTR3A
transmembrane transporter complex 1 HTR3A
Lipid-anchor, GPI-anchor 1 ACHE
sperm flagellum 1 DRD2
Membrane, caveola 2 ADRA1A, HTR2A
Cytoplasmic vesicle membrane 1 GPRC5A
cell body fiber 1 HTR2A
Cell projection, dendrite 3 DRD1, HTR1A, HTR2A
side of membrane 1 ACHE
secretory granule lumen 1 S100A12
secretory granule membrane 1 ITPR3
axon terminus 2 DRD2, NTS
voltage-gated calcium channel complex 1 CACNA1I
endocytic vesicle 1 DRD2
transport vesicle 1 NTS
Single-pass type IV membrane protein 1 MAOA
neurofilament 1 HTR2A
platelet dense tubular network membrane 1 ITPR3
Synapse, synaptosome 1 HTR2B
synaptic cleft 1 ACHE
dopaminergic synapse 1 DRD2
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
Cell projection, cilium membrane 1 DRD1
guanylate cyclase complex, soluble 1 GUCY1A1
transport vesicle membrane 1 ITPR3
G protein-coupled receptor complex 2 DRD1, DRD2
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
[Isoform H]: Cell membrane 1 ACHE
G protein-coupled serotonin receptor complex 3 HTR2A, HTR2B, HTR2C


文献列表

  • S K Hemrick-Luecke, R W Fuller. Involvement of 5-HT2A receptors in the elevation of rat serum corticosterone concentrations by quipazine and MK-212. European journal of pharmacology. 1996 Sep; 311(2-3):207-11. doi: 10.1016/0014-2999(96)00439-6. [PMID: 8891601]