naphthol (BioDeep_00000868150)

Main id: BioDeep_00000002138

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


InChI=1\C10H8O\c11-10-7-3-5-8-4-1-2-6-9(8)10\h1-7,11

化学式: C10H8O (144.0575)
中文名称: 1-萘酚, 萘酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C=CC=C2O
InChI: InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

16 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ALB, CAT, CYP3A4, HPGDS, NQO1, SULT1A1, TYR
Peripheral membrane protein 2 ACHE, HSD17B6
Endoplasmic reticulum membrane 8 CYP1A2, CYP3A4, UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B7
Nucleus 3 ACHE, ALB, NQO1
cytosol 6 ACP5, ALB, CAT, HPGDS, NQO1, SULT1A1
dendrite 1 NQO1
centrosome 1 ALB
nucleoplasm 1 HPGDS
Cell membrane 2 ACHE, MGAM
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 SLC45A2
Synapse 2 ACHE, NQO1
cell surface 1 ACHE
Golgi apparatus 2 ACHE, ALB
neuromuscular junction 1 ACHE
neuronal cell body 1 NQO1
Cytoplasm, cytosol 1 NQO1
Lysosome 2 ACP5, TYR
plasma membrane 4 ACHE, BCHE, MGAM, UGT1A1
Membrane 13 ACHE, ACP5, CAT, CYP3A4, MGAM, NQO1, SLC45A2, UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B7
apical plasma membrane 1 MGAM
extracellular exosome 3 ALB, CAT, MGAM
Lumenal side 1 HSD17B6
endoplasmic reticulum 7 ALB, HSD17B6, UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9
extracellular space 3 ACHE, ALB, BCHE
perinuclear region of cytoplasm 3 ACHE, TYR, UGT1A1
mitochondrion 1 CAT
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 7 CAT, CYP1A2, CYP3A4, HPGDS, HSD17B6, TYR, UGT1A6
Microsome membrane 3 CYP1A2, CYP3A4, HSD17B6
Single-pass type I membrane protein 1 TYR
Secreted 4 ACHE, ALB, BCHE, MGAM
extracellular region 5 ACHE, ALB, BCHE, CAT, MGAM
Single-pass membrane protein 7 MGAM, UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B7
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
anchoring junction 1 ALB
Melanosome membrane 2 SLC45A2, TYR
Golgi-associated vesicle 1 TYR
Cytoplasm, perinuclear region 1 UGT1A1
focal adhesion 1 CAT
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
ciliary basal body 1 ALB
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, BCHE
Lipid-anchor, GPI-anchor 1 ACHE
tertiary granule membrane 1 MGAM
Melanosome 1 TYR
side of membrane 1 ACHE
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 ALB, BCHE
platelet alpha granule lumen 1 ALB
nuclear envelope lumen 1 BCHE
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 MGAM
catalase complex 1 CAT
endoplasmic reticulum chaperone complex 1 UGT1A1
[Isoform H]: Cell membrane 1 ACHE
cytochrome complex 1 UGT1A1
ciliary transition fiber 1 ALB


文献列表

  • Najjapak Sooksawat, Duangrat Inthorn, Apisit Chittawanij, Alisa Vangnai, Pornpimol Kongtip, Susan Woskie. Phytoextraction Potential of Sunn Hemp, Sunflower, and Marigold for Carbaryl Contamination: Hydroponic Experiment. International journal of environmental research and public health. 2022 12; 19(24):. doi: 10.3390/ijerph192416482. [PMID: 36554374]
  • Zi-Jian Chen, Hui-Ling Wu, Yu-Dong Shen, Hong Wang, Yi-Feng Zhang, Bruce Hammock, Zhen-Feng Li, Lin Luo, Hong-Tao Lei, Zhen-Lin Xu. Phosphate-triggered ratiometric fluoroimmunoassay based on nanobody-alkaline phosphatase fusion for sensitive detection of 1-naphthol for the exposure assessment of pesticide carbaryl. Journal of hazardous materials. 2022 02; 424(Pt C):127411. doi: 10.1016/j.jhazmat.2021.127411. [PMID: 34629198]
  • Zhiping Che, Song Zhang, Jiaxuan He, Di Sun, Xiaolong Guo, Yuanhao Li, Lina Zhu, Yihao Guo, Yibo Liu, Yuee Tian, Xiaobo Huang, Shengming Liu, Genqiang Chen. Combinatorial Synthesis of Sulfonate Derivatives of α/β-Naphthol as Anti- Oomycete Agents. Combinatorial chemistry & high throughput screening. 2022; 25(12):2026-2032. doi: 10.2174/1386207325666220128120208. [PMID: 35088660]
  • Max Petitjean, José Ramón Isasi. Chitosan, xanthan and locust bean gum matrices crosslinked with β-cyclodextrin as green sorbents of aromatic compounds. International journal of biological macromolecules. 2021 Jun; 180(?):570-577. doi: 10.1016/j.ijbiomac.2021.03.098. [PMID: 33753196]
  • Zi-Jian Chen, Xi-Xia Liu, Zhi-Li Xiao, Hui-Jun Fu, Yu-Ping Huang, Shu-Yi Huang, Yu-Dong Shen, Fan He, Xing-Xing Yang, Bruce Hammock, Zhen-Lin Xu. Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and development of an easy-to-use ELISA in urine samples. Ecotoxicology and environmental safety. 2020 Jun; 196(?):110533. doi: 10.1016/j.ecoenv.2020.110533. [PMID: 32247241]
  • Akito Takeuchi, Sadao Nakamura, Akira Namera, Tomoaki Kondo, Hiroyuki Onuki, Shinobu Yamamoto, Shingo Okamura, Osamu Nishinoiri, Yoko Endo, Hiroyuki Miyauchi, Ginji Endo. Simple and reliable method to simultaneously determine urinary 1- and 2-naphthol using in situ derivatization and gas chromatography-mass spectrometry for biological monitoring of naphthalene exposure in occupational health practice. Journal of occupational health. 2020 Jan; 62(1):e12144. doi: 10.1002/1348-9585.12144. [PMID: 32713100]
  • Katrin Klotz, Tobias Weiß, Melanie Zobel, Daniel Bury, Dietmar Breuer, Silke Werner, Kirsten Sucker, Wolfgang Zschiesche, Thomas Göen, Thomas Brüning, Hans Drexler. Validity of different biomonitoring parameters in human urine for the assessment of occupational exposure to naphthalene. Archives of toxicology. 2019 08; 93(8):2185-2195. doi: 10.1007/s00204-019-02468-9. [PMID: 31222524]
  • Dan Huang, Tiecheng Wang, Kecheng Zhu, Song Zhao, Yafang Shi, Mao Ye, Chuanyi Wang, Hanzhong Jia. Low-molecular-weight organic acids impede the degradation of naphthol in iron oxides/persulfate systems: Implications for research experiments in pure conditions. Chemosphere. 2019 Jun; 225(?):1-8. doi: 10.1016/j.chemosphere.2019.02.127. [PMID: 30852260]
  • Wenyong Hu, Xiaobo Min, Xinyu Li, Jingyi Liu, Haibin Yu, Yuan Yang, Jiachao Zhang, Lin Luo, Liyuan Chai, Yaoyu Zhou. Enhanced degradation of 1-naphthol in landfill leachate using Arthrobacter sp. Environmental technology. 2019 Mar; 40(7):835-842. doi: 10.1080/09593330.2017.1408695. [PMID: 29168925]
  • Emila Dziewirska, Michał Radwan, Bartosz Wielgomas, Anna Klimowska, Paweł Radwan, Paweł Kałużny, Wojciech Hanke, Maciej Słodki, Joanna Jurewicz. Human Semen Quality, Sperm DNA Damage, and the Level of Urinary Concentrations of 1N and TCPY, the Biomarkers of Nonpersistent Insecticides. American journal of men's health. 2019 Jan; 13(1):1557988318816598. doi: 10.1177/1557988318816598. [PMID: 30813854]
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  • Jitendriya Swain, Monalisa Mohapatra, Santosh R Borkar, Indrapal Singh Aidhen, Ashok Kumar Mishra. Study of aqueous phase aggregation of FTY720 (fingolimod hydrochloride) and its effect on DMPC liposomes using fluorescent molecular probes. Physical chemistry chemical physics : PCCP. 2013 Nov; 15(41):17962-70. doi: 10.1039/c3cp53148a. [PMID: 24048224]
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  • Virginia C Moser, Pamela M Phillips, Katherine L McDaniel, Robert D Zehr, Denise K MacMillan, Robert C MacPhail. Carbaryl and 1-naphthol tissue levels and related cholinesterase inhibition in male Brown Norway rats from preweaning to senescence. Journal of toxicology and environmental health. Part A. 2013; 76(20):1151-67. doi: 10.1080/15287394.2013.844751. [PMID: 24279816]
  • Yun-feng He, Wang-zhen Zhang, Dan Kuang, Hua-xin Deng, Xiao-hai Li, Da-feng Lin, Qi-fei Deng, Kun Huang, Tang-chun Wu. [Effects of smoking on the concentrations of urinary 10 metabolites of polycyclic aromatic hydrocarbons in coke oven workers]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. 2012 Dec; 30(12):888-92. doi: NULL. [PMID: 23290639]
  • Nenad Manevski, Jari Yli-Kauhaluoma, Moshe Finel. UDP-glucuronic acid binds first and the aglycone substrate binds second to form a ternary complex in UGT1A9-catalyzed reactions, in both the presence and absence of bovine serum albumin. Drug metabolism and disposition: the biological fate of chemicals. 2012 Nov; 40(11):2192-203. doi: 10.1124/dmd.112.047746. [PMID: 22912433]
  • Jian Zhang, Xu Zhang, Juan Liu, Rong Li, Biao Shen. Isolation of a thermophilic bacterium, Geobacillus sp. SH-1, capable of degrading aliphatic hydrocarbons and naphthalene simultaneously, and identification of its naphthalene degrading pathway. Bioresource technology. 2012 Nov; 124(?):83-9. doi: 10.1016/j.biortech.2012.08.044. [PMID: 22985850]
  • Megumi Shintani, Yushi Matsuo, Shun Sakuraba, Nobuyuki Matubayasi. Interaction of naphthalene derivatives with lipids in membranes studied by the 1H-nuclear Overhauser effect and molecular dynamics simulation. Physical chemistry chemical physics : PCCP. 2012 Oct; 14(40):14049-60. doi: 10.1039/c2cp41984j. [PMID: 22983117]
  • Kanami Mori-Yasumoto, Ryoko Izumoto, Hiroyuki Fuchino, Takashi Ooi, Yutaka Agatsuma, Takenori Kusumi, Motoyoshi Satake, Setsuko Sekita. Leishmanicidal activities and cytotoxicities of bisnaphthoquinone analogues and naphthol derivatives from Burman Diospyros burmanica. Bioorganic & medicinal chemistry. 2012 Sep; 20(17):5215-9. doi: 10.1016/j.bmc.2012.06.055. [PMID: 22858297]
  • Babu A Manjasetty, Xiao-Hong Yu, Santosh Panjikar, Goro Taguchi, Mark R Chance, Chang-Jun Liu. Structural basis for modification of flavonol and naphthol glucoconjugates by Nicotiana tabacum malonyltransferase (NtMaT1). Planta. 2012 Sep; 236(3):781-93. doi: 10.1007/s00425-012-1660-8. [PMID: 22610270]
  • Juha Laitinen, Mauri Mäkelä, Jouni Mikkola, Ismo Huttu. Firefighters' multiple exposure assessments in practice. Toxicology letters. 2012 Aug; 213(1):129-33. doi: 10.1016/j.toxlet.2012.06.005. [PMID: 22710199]
  • Manuela A Orjuela, Xinhua Liu, Rachel L Miller, Dorothy Warburton, Deliang Tang, Vaidehi Jobanputra, Lori Hoepner, Ida Hui Suen, Silvia Diaz-Carreño, Zheng Li, Andreas Sjodin, Frederica P Perera. Urinary naphthol metabolites and chromosomal aberrations in 5-year-old children. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2012 Jul; 21(7):1191-202. doi: 10.1158/1055-9965.epi-12-0214. [PMID: 22573794]
  • Ruifang Fan, Robert Ramage, Dongli Wang, Junqiang Zhou, Jianwen She. Determination of ten monohydroxylated polycyclic aromatic hydrocarbons by liquid-liquid extraction and liquid chromatography/tandem mass spectrometry. Talanta. 2012 May; 93(?):383-91. doi: 10.1016/j.talanta.2012.02.059. [PMID: 22483926]
  • Onur Erdem, Ahmet Sayal, Ayşe Eken, Cemal Akay, Ahmet Aydın. Evaluation of genotoxic and oxidative effects in workers exposed to jet propulsion fuel. International archives of occupational and environmental health. 2012 May; 85(4):353-61. doi: 10.1007/s00420-011-0676-x. [PMID: 21755367]
  • Gianluca Adornetto, Giulia Volpe, Alessia De Stefano, Sonia Martini, Giuseppina Gallucci, Angelo Manzoni, Sergio Bernardini, Marco Mascini, Danila Moscone. An ELIME assay for the rapid diagnosis of coeliac disease. Analytical and bioanalytical chemistry. 2012 May; 403(4):1191-4. doi: 10.1007/s00216-011-5702-z. [PMID: 22258206]
  • Jun-liang Wang, Qing Xia, An-ping Zhang, Xiao-yan Hu, Chun-mian Lin. Determination of organophosphorus pesticide residues in vegetables by an enzyme inhibition method using α-naphthyl acetate esterase extracted from wheat flour. Journal of Zhejiang University. Science. B. 2012 Apr; 13(4):267-73. doi: 10.1631/jzus.b11a0180. [PMID: 22467368]
  • Shitong Yang, Zhiqiang Guo, Guodong Sheng, Xiangke Wang. Investigation of the sequestration mechanisms of Cd(II) and 1-naphthol on discharged multi-walled carbon nanotubes in aqueous environment. The Science of the total environment. 2012 Mar; 420(?):214-21. doi: 10.1016/j.scitotenv.2012.01.018. [PMID: 22330423]
  • Thomas Göen, Karl-Heinz Schaller, Hans Drexler. External quality assessment of human biomonitoring in the range of environmental exposure levels. International journal of hygiene and environmental health. 2012 Feb; 215(2):229-32. doi: 10.1016/j.ijheh.2011.08.012. [PMID: 21937272]
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