Krebiozen (BioDeep_00000864760)
Main id: BioDeep_00000399890
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C4H7N3O (113.0589092)
中文名称: 肌酐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1CC(=O)N=C1N
InChI: InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
描述信息
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles.
Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles.
同义名列表
58 个代谢物同义名
InChI=1\C4H7N3O\c1-7-2-3(8)6-4(7)5\h2H2,1H3,(H2,5,6,8; 4H-Imidazol-4-one, 2-imino-1,5-dihydro-1-methyl-; 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-; 2-amino-1-methyl-1,5-dihydro-4H-imidazol-4-one; 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one; 2-imino-1-methylimidazolidin-4-one; 2-imino-1-methyl-4-imidazolidinone; 2-amino-1-methyl-5H-imidazol-4-one; 1-methyl-2-amino-imidazol-4-one; Creatinine standard solution; 1-Methylhydantoin-2-imide; 2-Imino-N-methylhydantoin; Creatinine (VAN) (8CI); 1-Methylglycocyamidine; SDCCGMLS-0066864.P001; Creatinine,heated; nchembio.78-comp6; Spectrum3_001717; Spectrum4_001806; Spectrum2_000764; EINECS 200-466-7; Spectrum5_000511; SPECTRUM1600300; NCGC00095762-01; AO-840\40806907; Spectrum_000429; Creatinine (NF); BSPBio_003334; KBioSS_000909; KBioGR_002415; DivK1c_000351; ZINC00967189; KBio1_000351; KBio2_006045; KBio3_002554; NINDS_000351; SPBio_000808; KBio2_003477; KBio2_000909; AIDS-166904; IDI1_000351; CHEBI:16737; C3488_SIGMA; C3613_SIGMA; 82016-55-5; BB_NC-0783; Creatinine; AIDS166904; 15231-31-9; 45514-66-7; C4255_SIAL; Krebiozen; AI3-15321; NSC 13123; NSC13123; 60-27-5; D03600; C00791
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:16737
- KEGG: C00791
- PubChem: 588
- ChEMBL: CHEMBL65567
- MeSH: Creatinine
- CAS: 62708-52-5
- CAS: 60-27-5
- PubChem: 4049
- 3DMET: B00175
- NIKKAJI: J1.397H
- medchemexpress: HY-B0504
分类词条
相关代谢途径
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 7962 - Cyprinus carpio: -
- 33090 - 椿皮: -
- 569774 - 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Shengchun Liao, Yurou Chen, Shuting Wang, Chen Wang, Chaoyang Ye. Shenkang injection for the treatment of acute kidney injury: a systematic review and meta-analysis.
Renal failure.
2024 Dec; 46(1):2338566. doi:
10.1080/0886022x.2024.2338566
. [PMID: 38655870] - Ruixue Tian, Shuqin Tang, Jingyu Zhao, Yajie Hao, Limei Zhao, Xiutao Han, Xingru Wang, Lijun Zhang, Rongshan Li, Xiaoshuang Zhou. β-Hydroxybutyrate Protects Against Cisplatin-Induced Renal Damage via Regulating Ferroptosis.
Renal failure.
2024 Dec; 46(1):2354918. doi:
10.1080/0886022x.2024.2354918
. [PMID: 38757723] - Shisheng Han, Meng Jia, Wenli Yuan, Yi Wang, Yan Lu, Yanqiu Xu, Li Shang. The association between peripheral eosinophil count and chronic kidney disease: evidence from NHANES 1999-2018.
Renal failure.
2024 Dec; 46(1):2319324. doi:
10.1080/0886022x.2024.2319324
. [PMID: 38390735] - Yizeng Xu, Fang Lu, Meng Wang, Lingchen Wang, Chaoyang Ye, Shuohui Yang, Chen Wang. Shen Shuai II recipe improves renal hypoxia to attenuate renal injury in 5/6 renal ablation/infarction rats and effect evaluation using blood oxygenation level-dependent functional magnetic resonance imaging.
Renal failure.
2024 Dec; 46(1):2338565. doi:
10.1080/0886022x.2024.2338565
. [PMID: 38622926] - Meifang Liu, Yuan Ming Di, Brian May, Anthony Lin Zhang, Lei Zhang, Junhui Chen, Ruobing Wang, Xusheng Liu, Charlie Changli Xue. Renal protective effects and mechanisms of Astragalus membranaceus for diabetic kidney disease in animal models: An updated systematic review and meta-analysis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155646. doi:
10.1016/j.phymed.2024.155646
. [PMID: 38733903] - Ying-Ling Zhang, Si-Min Chen, Yi-Jie Song, Md Ariful Islam, Pei-Li Rao, Meng-Jie Zhu, Wen-Yi Gu, Yu Xu, Hong-Xi Xu. Red ginseng ameliorates lipotoxicity-induced renal fibrosis in hyperuricemia mice.
Journal of ethnopharmacology.
2024 Jun; 327(?):118014. doi:
10.1016/j.jep.2024.118014
. [PMID: 38460576] - Mahdi Babamir Satehi, Mahdi Karimi, Zohreh Farrokhian, Fateme Pakbaz. The effect of aqueous extract of Iranian oak (Quercus brantii) on antioxidant capacity and oxidative stress in beta-thalassemia patients: Randomized controlled trial.
Clinical nutrition ESPEN.
2024 Jun; 61(?):230-236. doi:
10.1016/j.clnesp.2024.03.037
. [PMID: 38777439] - Wen-Wen Liu, Hong-Jing Dong, Zhe Zhang, Xin-Hui Ma, Shuang Liu, Wei Huang, Xiao Wang. Analyzing chemical composition of Sargentodoxae caulis water extract and their hypouricemia effect in hyperuricemic mice.
Fitoterapia.
2024 Jun; 175(?):105926. doi:
10.1016/j.fitote.2024.105926
. [PMID: 38537887] - ChaoQiong Zhou, QianRong Xie, HuaLi Wang, Feng Wu, DaHai He, Ying Huang, Ying He, ShiRong Dai, Jie Chen, LiRui Kong, Yan Zhang. Biological variation in the estimated glomerular filtration rate of healthy individuals within 24 h calculated using 2021CKD-EPI equations.
Irish journal of medical science.
2024 Jun; 193(3):1613-1620. doi:
10.1007/s11845-024-03621-9
. [PMID: 38308766] - Divya Bisht, Deena Prakash, Ramesh Kumar, Arvind Kumar Shakya, Sadhana Shrivastava. Phytochemical profiling and nephroprotective potential of ethanolic leaf extract of Polyalthia longifolia against cisplatin-induced oxidative stress in rat model.
Journal of ethnopharmacology.
2024 May; 326(?):117922. doi:
10.1016/j.jep.2024.117922
. [PMID: 38403004] - Xiayan Yu, Wenjing Qiang, Kexin Gong, Yidan Cao, Shuangqin Yan, Guopeng Gao, Fangbiao Tao, Beibei Zhu. No role of the third-trimester inflammatory factors in the association of gestational diabetes mellitus with postpartum cardiometabolic indicators.
BMC pregnancy and childbirth.
2024 May; 24(1):361. doi:
10.1186/s12884-024-06563-3
. [PMID: 38750471] - Jia-Jia Wu, Tian-Yi Zhang, Ying-Hui Qi, Min-Yan Zhu, Yan Fang, Chao-Jun Qi, Li-Ou Cao, Ji-Fang Lu, Bo-Han Lu, Lu-Min Tang, Jian-Xiao Shen, Shan Mou. Efficacy and safety of Yiqi Peiyuan granules for improving the short-term prognosis of patients with acute kidney injury: A multicenter, double-blind, placebo-controlled, randomized trial.
Journal of integrative medicine.
2024 May; 22(3):279-285. doi:
10.1016/j.joim.2024.04.004
. [PMID: 38688809] - Yajie Xu, Pan Chen, Long Sun, Yan Zou, Lixing Zhang, Wanghai Tang, Tingji Zhang, Jinlin Huo, Jin Zhou. Effect and mechanism of Yiqing decoction on hyperuricemia rats.
Cellular and molecular biology (Noisy-le-Grand, France).
2024 Apr; 70(4):217-224. doi:
10.14715/cmb/2024.70.4.34
. [PMID: 38678602] - Mostafa Salama, Peter J Tebben, Alaa Al Nofal. An infant developing hypercalcemia and hypophosphatemia due to the use of exclusively almond milk.
Journal of pediatric endocrinology & metabolism : JPEM.
2024 Apr; 37(4):375-379. doi:
10.1515/jpem-2023-0494
. [PMID: 38414167] - Bo Zou, Qiaoqiao Yuan, Hongyu Luo, Munan Wang, Xin Chen, Zuling Gao, Jianwei Wang, Yongbo Peng, Haijun Yang, Feng Dai, Xuekuan Huang. Combination of Fushengong decoction with Western medicine on patients with chronic renal failure: An observational study.
Medicine.
2024 Apr; 103(15):e37473. doi:
10.1097/md.0000000000037473
. [PMID: 38608120] - Saima Jadoon, Qurban Ali, Adnan Sami, Muhammad Zeeshan Haider, Muhammad Ashfaq, Muhammad Arshad Javed, Mudassar Ali Khan. DNA damage in inhabitants exposed to heavy metals near Hudiara drain, Lahore, Pakistan.
Scientific reports.
2024 04; 14(1):8408. doi:
10.1038/s41598-024-58655-x
. [PMID: 38600156] - Jiayou Luo, Miyang Luo, Atipatsa C Kaminga, Jia Wei, Wen Dai, Yunlong Peng, Kunyan Zhao, Yamei Duan, Xiang Xiao, SiSi Ouyang, Zhenzhen Yao, Yixu Liu, Xiongfeng Pan. Integrative metabolomics highlights gut microbiota metabolites as novel NAFLD-related candidate biomarkers in children.
Microbiology spectrum.
2024 Apr; 12(4):e0523022. doi:
10.1128/spectrum.05230-22
. [PMID: 38445874] - Thaise Boeing, Alana Bittencourt F Lima, Maria Eduarda Busana, Luísa Nathália Bolda Mariano, Luisa Mota da Silva, Rita de Cássia Vilhena da Silva, Priscila de Souza. Characterization of Diclofenac-induced Renal Damage in Normotensive and Hypertensive Rats: A Comparative Analysis.
Drug research.
2024 Apr; 74(4):171-179. doi:
10.1055/a-2277-8458
. [PMID: 38503307] - Jen-Hsuan Wu, Kuo-Jen Lin, Ying-Hao Hsu, Yang-Jen Chiang, Sheng-Hsien Chu, Chih-Te Lin, Pai-Yen Pan, Sy-Yuan Chen, Jui-Yen Wang, Hsu-Han Wang. Festivity: The Effects of Traditional Holidays on the Graft Function Among Stable Kidney Recipients.
Transplantation proceedings.
2024 Apr; 56(3):546-549. doi:
10.1016/j.transproceed.2024.02.018
. [PMID: 38523012] - Farah Aziz, Mohammad Fareed Khan, Amna Moiz. Gestational diabetes mellitus, hypertension, and dyslipidemia as the risk factors of preeclampsia.
Scientific reports.
2024 03; 14(1):6182. doi:
10.1038/s41598-024-56790-z
. [PMID: 38486097] - Rhulani Makhuvele, Kenn Foubert, Nina Hermans, Luc Pieters, Luc Verschaeve, Esameldin Elgorashi. Hepatoprotective effects of leaf extract of Annona senegalensis against aflatoxin B1 toxicity in rats.
The Onderstepoort journal of veterinary research.
2024 Mar; 91(1):e1-e6. doi:
10.4102/ojvr.v91i1.2133
. [PMID: 38572889] - Abdullah B Yıldız, Sezan Vehbi, Sidar Copur, Bengi Gurses, Dimitrie Siriopol, Bahar Afak Durur Karakaya, Nuri B Hasbal, Bahar Tekin, Murat Akyıldız, Daniel H van Raalte, Mario Cozzolino, Mehmet Kanbay. Kidney and liver fat accumulation: from imaging to clinical consequences.
Journal of nephrology.
2024 Mar; 37(2):483-490. doi:
10.1007/s40620-023-01824-4
. [PMID: 38133740] - Ji Huang, Cong Cheng, Kangxin Li, Chunping Zhu, Youshun Liu. Effectiveness and Safety of Tenofovir Alafenamide Fumarate in the Prevention of Perinatal Hepatitis B Transmission: A Meta-Analysis.
Digestive diseases and sciences.
2024 Mar; 69(3):978-988. doi:
10.1007/s10620-023-08258-9
. [PMID: 38341392] - Meng-Ke Bai, Xiao-Qing Yang, Xiao-Feng Mei, Jin-Gang Li, Yue-Li Yang, Yan-Jie Huang. [Urinary protein and renal pathological features in children with immunoglobulin A vasculitis with nephritis and hypercoagulability].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics.
2024 Feb; 26(2):164-168. doi:
10.7499/j.issn.1008-8830.2309033
. [PMID: 38436314] - Sumei Li, Shouping Yuan, Jintian Zhang, Feipeng Xu, Feng Zhu. The effect of periodic resistance training on obese patients with type 2 diabetic nephropathy.
Scientific reports.
2024 02; 14(1):2761. doi:
10.1038/s41598-024-53333-4
. [PMID: 38307949] - Yang Zhang, Huajiang Zhao, Jing Zhang. Hyaluronidase inhibitor sHA2.75 alleviates ischemia-reperfusion-induced acute kidney injury.
Cell cycle (Georgetown, Tex.).
2024 Feb; 23(3):248-261. doi:
10.1080/15384101.2024.2309019
. [PMID: 38526145] - Hend A Essa, Salwa M El Shebini, Maha I A Moaty, Nihad H Ahmed, Ahmed M S Hussein, Magda S Mohamed. Efficacy of parsley seed-supplemented bread in improving serum osteopontin level and renal health in obese women: A nutritional intervention study.
Clinical nutrition ESPEN.
2024 02; 59(?):287-295. doi:
10.1016/j.clnesp.2023.12.022
. [PMID: 38220388] - Chloe Orkin, Jean-Michel Molina, Pedro Cahn, Johannes Lombaard, Khuanchai Supparatpinyo, Sushma Kumar, Havilland Campbell, Hong Wan, Valerie Teal, Zhi Jin Xu, Ernest Asante-Appiah, Peter Sklar, Hedy Teppler, Rima Lahoulou. Safety and efficacy of doravirine as first-line therapy in adults with HIV-1: week 192 results from the open-label extensions of the DRIVE-FORWARD and DRIVE-AHEAD phase 3 trials.
The lancet. HIV.
2024 Feb; 11(2):e75-e85. doi:
10.1016/s2352-3018(23)00258-8
. [PMID: 38141637] - Fatemeh Mohammadi, Amirhossein Yadegar, Soghra Rabizadeh, Aryan Ayati, Seyed Arsalan Seyedi, Seyed Ali Nabipoorashrafi, Alireza Esteghamati, Manouchehr Nakhjavani. Correlates of normal and decreased HDL cholesterol levels in type 2 diabetes: a cohort-based cross-sectional study.
Lipids in health and disease.
2024 Jan; 23(1):18. doi:
10.1186/s12944-024-02010-6
. [PMID: 38243302] - Özge Kendirlinan, Yurdun Kuyucu, Bilge Güzelel, Ebru Dündar Yenilmez, Abdullah Tuli, Gülşah Seydaoğlu, Ufuk Özgü Mete. Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity.
Ultrastructural pathology.
2024 Jan; 48(1):29-41. doi:
10.1080/01913123.2023.2278629
. [PMID: 37970647] - Jinshu Chen, Pihou Chen, Yijin Song, Jiaxin Wei, Fan Wu, Jing Sun, Zhiquan Xu. STING upregulation mediates ferroptosis and inflammatory response in lupus nephritis by upregulating TBK1 and activating NF-κB signal pathway.
Journal of biosciences.
2024; 49(?):. doi:
. [PMID: 38186000]
- Jianhua Wang, Yang Wang, Jie Yin, Lei Xia. Efficacy of Flexible Ureteroscopy Lithotripsy and Percutaneous Nephrolithotomy in the Treatment of Patients with Kidney Stones and Their Impact on Inflammatory Response and Renal Function.
Annali italiani di chirurgia.
2024; 95(2):220-226. doi:
10.62713/aic.3175
. [PMID: 38684501] - Dan Chen, Leying Wang, Xiaoyan Guo, Zijun Zhang, Xizhan Xu, Zi-Bing Jin, Qingfeng Liang. Evaluation of Limbal Stem Cells in Patients With Type 2 Diabetes: An In Vivo Confocal Microscopy Study.
Cornea.
2024 Jan; 43(1):67-75. doi:
10.1097/ico.0000000000003334
. [PMID: 37399570] - Ahmed I Abd El Maksoud, Ahmed A Al-Karmalawy, Dalia ElEbeedy, Aml Ghanem, Yasmin Rasheed, Ibrahim A Ibrahim, Reem A Elghaish, Amany Belal, Mona A Raslan, Rehab F Taher. Symbiotic Antidiabetic Effect of Lactobacillus casei and the Bioactive Extract of Cleome droserifolia (Forssk.) Del. on Mice with Type 2 Diabetes Induced by Alloxan.
Chemistry & biodiversity.
2024 Jan; 21(1):e202301397. doi:
10.1002/cbdv.202301397
. [PMID: 38078801] - Carlo Palizzotto, Felippo Ferri, Carolina Callegari, Francesco Rossi, Marcello Manfredi, Laura Carcangiu, Gabriele Gerardi, Silvia Ferro, Laura Cavicchioli, Elizabeth Müller, Marco Weiss, Anne-Catherine Vogt, Francesca Lavatelli, Stefano Ricagno, Karyl Hurley, Eric Zini. Renal amyloid-A amyloidosis in cats: Characterization of proteinuria and biomarker discovery, and associations with kidney histology.
Journal of veterinary internal medicine.
2024 Jan; 38(1):205-215. doi:
10.1111/jvim.16920
. [PMID: 37991136] - Soroush Masrouri, Seyed Saeed Tamehri Zadeh, Mehdi Pishgahi, Fereidoun Azizi, Michael D Shapiro, Farzad Hadaegh. Kidney function decline is associated with mortality events: over a decade of follow-up from Tehran Lipid and Glucose Study.
Journal of nephrology.
2024 01; 37(1):107-118. doi:
10.1007/s40620-023-01756-z
. [PMID: 37665526] - Fatma Ben Mansour, Habib Ayadi, Jos van Pelt, Abdelfattah Elfeki, Khaled Bellassoued. Antioxidant and Protective Effect of Ocimum basilicum Seeds Extract on Renal Toxicity Induced by Carbon Tetrachloride in Rats.
Journal of medicinal food.
2024 Jan; 27(1):60-71. doi:
10.1089/jmf.2023.0184
. [PMID: 38150214] - Yun Xie, Qin Guo, Bo Yang, Pan Xie, Jingxiao Zhang, Wei Lu, Claudio Ronco, Gengru Jiang. Tissue Inhibitor Metalloproteinase-2·IGF-Binding Protein 7 for the Prediction of Acute Kidney Injury following Cardiac Surgery.
Cardiorenal medicine.
2024; 14(1):251-260. doi:
10.1159/000538031
. [PMID: 38588650] - Handan Mert, Nihan Mert, Salih Cibuk, Serkan Yildirim, Nihat Mert. Antidiabetic Effect of Fig Seed Oil in Rats with Diabetes Induced by Streptozotocin.
Journal of oleo science.
2024; 73(5):717-727. doi:
10.5650/jos.ess23255
. [PMID: 38692894] - Melva Louisa, Erico Wanafri, Wawaimuli Arozal, Ni Made Dwi Sandhiutami, Ahmad Muhammad Basalamah. Nanocurcumin preserves kidney function and haematology parameters in DMBA-induced ovarian cancer treated with cisplatin via its antioxidative and anti-inflammatory effect in rats.
Pharmaceutical biology.
2023 Dec; 61(1):298-305. doi:
10.1080/13880209.2023.2166965
. [PMID: 36708211] - David J Tunnicliffe, Suetonia C Palmer, Brydee A Cashmore, Valeria M Saglimbene, Rathika Krishnasamy, Kelly Lambert, David W Johnson, Jonathan C Craig, Giovanni Fm Strippoli. HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis.
The Cochrane database of systematic reviews.
2023 11; 11(?):CD007784. doi:
10.1002/14651858.cd007784.pub3
. [PMID: 38018702] - Jacob Lessard-Lord, Serge Auger, Sarah Demers, Pier-Luc Plante, Pierre Picard, Yves Desjardins. Automated High-Throughput Quantification of Phenyl-γ-valerolactones and Creatinine in Urine by Laser Diode Thermal Desorption.
Journal of agricultural and food chemistry.
2023 Nov; 71(44):16787-16796. doi:
10.1021/acs.jafc.3c03888
. [PMID: 37890868] - H A Al-Amer, N S Al-Sowayan, H A Alfheeaid, S A Althwab, S A Alrobaish, E M Hamad, K H Musa, H M Mousa. Oral administration of naringenin and a mixture of coconut water and Arabic gum attenuate oxidative stress and lipid peroxidation in gentamicin-induced nephrotoxicity in rats.
European review for medical and pharmacological sciences.
2023 Nov; 27(21):10427-10437. doi:
10.26355/eurrev_202311_34317
. [PMID: 37975366] - Guang Yang, Ling Zhi Wang, Rong Zhang, Xiao Yu Zhang, Yue Yu, Hai Rong Ma, Xiao Gang He. Study on the Correlation between Blood Urea Nitrogen, Creatinine Level, Proteinuria and Parkinson's Disease.
Neurology India.
2023 Nov; 71(6):1217-1221. doi:
10.4103/0028-3886.391388
. [PMID: 38174461] - Réka Szentimrei, Hajnalka Lőrincz, Anita Szentpéteri, Viktória Evelin Varga, Ildikó Seres, Éva Varga, Balázs Nemes, Mariann Harangi, György Paragh. Assessment of amino-terminal C-type natriuretic peptide serum level and its correlation with high-density lipoprotein structure and function in patients with end stage renal disease before and after kidney transplantation.
Chemico-biological interactions.
2023 Nov; 385(?):110749. doi:
10.1016/j.cbi.2023.110749
. [PMID: 37802408] - Muhammad Sajid, Syed Atif Hasan Naqvi, Muhammad Riaz, Ummad Ud Din Umar, Nasreen Nasreen, Adil Khan, Mourad Ben Said. Molecular detection of Babesia ovis and blood parameters' investigation reveal hematological and biochemical alterations in babesiosis-infected Lohi sheep in Multan, Pakistan.
Open veterinary journal.
2023 Nov; 13(11):1400-1408. doi:
10.5455/ovj.2023.v13.i11.2
. [PMID: 38107231] - Kaifa Tang, Shenghan Xu, Pan Chen, Ji Cai, Tao Huang, Miao Liu, Wei Li, Ying Yu, Bangwei Che, Wenjun Zhang. Potential role of glutathione S‑transferase M1 gene polymorphism in kidney calcium oxalate stone formation.
International urology and nephrology.
2023 Oct; ?(?):. doi:
10.1007/s11255-023-03846-0
. [PMID: 37891380] - Xiaoqian Li, Yongqing Gu, Lihong Ren, Qingqing Cai, Yan Qiu, Jie He, Wei Qu, Wei Ji. Study of hispidulin in the treatment of uric acid nephropathy based on NF-κB signaling pathway.
Chemical biology & drug design.
2023 Oct; ?(?):. doi:
10.1111/cbdd.14367
. [PMID: 37880153] - Min Qiu, You Long Zong, Bin Shuai Wang, Bin Yang, Chu Xiao Xu, Zheng Hui Sun, Min Lu, Lei Zhao, Jian Lu, Cheng Liu, Xiao Jun Tian, Lu Lin Ma. [Treatment outcome of laparoscopic partial nephrectomy in patients with renal tumors of moderate to high complexity].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences.
2023 Oct; 55(5):833-837. doi:
"
. [PMID: 37807736] - Rakesh Kumar, Pallavi Bhardwaj, Mridul Soni, Rahul Singh, Sahil Choudhary, Nitin Virmani, R K Asrani, Vikram Patial, Dixit Sharma, V K Gupta, B N Tripathi. Modulation of mammary tumour progression using murine model by ethanol root extract of Saussurea costus (falc.) lipsch.
Journal of ethnopharmacology.
2023 Oct; 319(Pt 3):117302. doi:
10.1016/j.jep.2023.117302
. [PMID: 37858751] - Ghizlane Nouioura, Tayeb Kettani, Meryem Tourabi, Layla Tahiri Elousrouti, Omkulthom Al Kamaly, Samar Zuhair Alshawwa, Abdelaaty A Shahat, Abdulsalam Alhalmi, Badiaa Lyoussi, Elhoussine Derwich. The Protective Potential of Petroselinum crispum (Mill.) Fuss. on Paracetamol-Induced Hepatio-Renal Toxicity and Antiproteinuric Effect: A Biochemical, Hematological, and Histopathological Study.
Medicina (Kaunas, Lithuania).
2023 Oct; 59(10):. doi:
10.3390/medicina59101814
. [PMID: 37893532] - Zhenwei Wang, Weibin Du, Yuanbin Ou, Meichun Han, Jintao Hu, Renfu Quan. Association between the ratio of serum creatinine to cystatin C and bone mineral density in middle-aged and older adults: a cross-sectional study from NHANES database.
The Journal of international medical research.
2023 Oct; 51(10):3000605231206305. doi:
10.1177/03000605231206305
. [PMID: 37882728] - Nabil Abbas Soliman, Sherif Wajih Mansour, Mohamed Ahmed Ammar, Noura Ahmed Hassan, Rehab Hamed Abdallah Mohamed. Possible role of pomegranate fruit in reversing renal damage in rats exposed to Phenylhydrazine.
Open veterinary journal.
2023 Oct; 13(10):1268-1276. doi:
10.5455/ovj.2023.v13.i10.5
. [PMID: 38027401] - Minghao Lin, Hui Zhang, Shilin Liu, Andong Li, Zheng Nan. Efficacy of 'Dihuang pill prescriptions' combined with conventional treatment for diabetic kidney disease: A network meta-analysis and systematic review.
Medicine.
2023 Sep; 102(39):e35290. doi:
10.1097/md.0000000000035290
. [PMID: 37773831] - Pedro de Padua G Amatto, Lucas Chaves, Giovana Graça Braga, Fábio Carmona, Ana Maria Soares Pereira. Effect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis.
Journal of ethnopharmacology.
2023 Sep; 319(Pt 2):117255. doi:
10.1016/j.jep.2023.117255
. [PMID: 37778521] - Iqra Khurram, Muhammad Umer Khan, Saooda Ibrahim, Ayman Saleem, Zaman Khan, Muhammad Mubeen, Arooj Khawar, Qurban Ali. Efficacy of cell-free DNA as a diagnostic biomarker in breast cancer patients.
Scientific reports.
2023 09; 13(1):15347. doi:
10.1038/s41598-023-42726-6
. [PMID: 37715016] - Yajiao Wang, Xia Xu, Shuqing Shi, Xiya Gao, Yumeng Li, Huaqin Wu, Qingqiao Song, Bingxuan Zhang. Blood urea nitrogen to creatinine ratio and long-term survival in patients with chronic heart failure.
European journal of medical research.
2023 Sep; 28(1):343. doi:
10.1186/s40001-023-01066-x
. [PMID: 37710326] - Yan Zhang, Yao Li, Chang Li, Yani Zhao, Lu Xu, Shanbo Ma, Fen Lin, Yanhua Xie, Junming An, Siwang Wang. Paeonia × suffruticosa Andrews leaf extract and its main component apigenin 7-O-glucoside ameliorate hyperuricemia by inhibiting xanthine oxidase activity and regulating renal urate transporters.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Sep; 118(?):154957. doi:
10.1016/j.phymed.2023.154957
. [PMID: 37478683] - Fengxiang Bao, Chengjun Yang, Guohui Zhou. [Predictive value of hemoglobin to serum creatinine ratio combined with serum uric acid for in-hospital mortality after emergency percutaneous coronary intervention in patients with acute myocardial infarction].
Zhonghua wei zhong bing ji jiu yi xue.
2023 Sep; 35(9):951-957. doi:
10.3760/cma.j.cn121430-20230418-00291
. [PMID: 37803954] - Dana Bielopolski, Renana Yemini, Aviad Gravetz, Oz Yoskovitch, Andrei Keidar, Idan Carmeli, Eytan Mor, Ruth Rahamimov, Benaya Rozen-Zvi, Eviatar Nesher. Bariatric Surgery in Severely Obese Kidney Donors Before Kidney Transplantation: A Retrospective Study.
Transplantation.
2023 09; 107(9):2018-2027. doi:
10.1097/tp.0000000000004645
. [PMID: 37291708] - Wenquan Hou, Tongtong Shi, Yong Li, Wen Li, Menghua Xu, Feng Peng. Soluble suppression of tumorigenicity 2 associated with fulminant myocarditis in children: A retrospective observational study.
Medicine.
2023 Aug; 102(34):e34784. doi:
10.1097/md.0000000000034784
. [PMID: 37653801] - Yuan Lin, Tze-Fan Chao, Ming-Lung Tsai, Chin-Ju Tseng, Te-Hsiung Wang, Chih-Hsiang Chang, Yu-Sheng Lin, Ning-I Yang, Pao-Hsien Chu, Ming-Jui Hung, Victor Chien-Chia Wu, Tien-Hsing Chen. Cardiovascular and renal outcomes in patients with atrial fibrillation and stage 4-5 chronic kidney disease receiving direct oral anticoagulants: a multicenter retrospective cohort study.
Journal of thrombosis and thrombolysis.
2023 Aug; ?(?):. doi:
10.1007/s11239-023-02885-9
. [PMID: 37605063] - Xiaxuan Huang, Shiqi Yuan, Yitong Ling, Hongtao Cheng, Shanyuan Tan, Anding Xu, Jun Lyu. Evaluating the effect of kidney function on brain volumes and dementia risk in the UK Biobank.
Archives of gerontology and geriatrics.
2023 Aug; 116(?):105157. doi:
10.1016/j.archger.2023.105157
. [PMID: 37634304] - Kun Shang, Xiang Ning, Jiangying Kuang, Aiying Xue, Xiao Yan, Huiqiang Chen. Hypertension and cystatin C account for sex differences in serum homocysteine levels in acute coronary syndrome subjects with normal serum creatinine.
Journal of health, population, and nutrition.
2023 08; 42(1):81. doi:
10.1186/s41043-023-00430-1
. [PMID: 37587534] - Yueyi Zhang, Shan Wang, Xuan Dai, Tianyuan Liu, Yage Liu, Hanfen Shi, Jiyuan Yin, Tianshu Xu, Yanfei Zhang, Dandan Zhao, Vasily Sukhorukov, Alexander N Orekhov, Sihua Gao, Lili Wang, Dongwei Zhang. Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Journal of ethnopharmacology.
2023 Aug; 312(?):116530. doi:
10.1016/j.jep.2023.116530
. [PMID: 37098372] - Xiaoqing Jia, Rong Li, Xiaoting Zhang, Tao Zhou, Dalong Sun, Na Yang, Zheng Luo. Increased age, bilirubin, international normalized ratio, and creatinine score to triglyceride ratio are associated with alcohol-associated primary liver carcinoma: a single-centered retrospective study.
Lipids in health and disease.
2023 Aug; 22(1):117. doi:
10.1186/s12944-023-01888-y
. [PMID: 37537579] - Emily Lawson, Vamsee Vemulapalli, Anthony Barnes, Sara Scott, Kathleen Wyne, Summit Shah. Applying National Diabetic Care Standards for the Management of a Hispanic Population Attending a Free Clinic.
Journal of community health.
2023 08; 48(4):576-584. doi:
10.1007/s10900-023-01199-4
. [PMID: 36752869] - Jianmei Zhou, Shuzhen Sun, Dongfeng Zhang, Jianhua Mao, Huijie Xiao, Yong Yao, Fang Wang, Lichun Yu, Ling Liu, Chunyue Feng, Chenglong Li, Baige Su, Hongwen Zhang, Xiaoyu Liu, Ke Xu, Wenjun Ju, Xuhui Zhong, Jie Ding. Urinary epidermal growth factor predicts complete remission of proteinuria in Chinese children with IgA nephropathy.
Pediatric research.
2023 08; 94(2):747-755. doi:
10.1038/s41390-023-02542-0
. [PMID: 36864281] - Ou Wu, Chengda Yuan, Jianhang Leng, Xingyu Zhang, Wei Liu, Fenfang Yang, Hu Zhang, Jiajia Li, Saber Khederzadeh, Zhizhi Jiang, Hangyan Fang, Xiaodong Liu, Xi Lu, Jiangwei Xia. Colorable role of interleukin (IL)-6 in obesity hypertension: A hint from a Chinese adult case-control study.
Cytokine.
2023 08; 168(?):156226. doi:
10.1016/j.cyto.2023.156226
. [PMID: 37235887] - Guo Zhaoan, Sun Lina, Liu Yingying, L I Ruifeng, Liu Chong, Diao Ke, Shi Jing, Sun Jun. Qizhi Jiangtang capsule activates podocyte autophagy in diabetic kidney disease by inhibiting phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2023 Aug; 43(4):667-675. doi:
10.19852/j.cnki.jtcm.20230428.001
. [PMID: 37454251] - Wei Shi, Daofei Song, Dan Chen, Wei Duan, Jing Zhang. The association of thyroid parameters with markers of chronic kidney disease in euthyroid patients with type 2 diabetes.
Endocrine journal.
2023 Jul; 70(7):687-696. doi:
10.1507/endocrj.ej22-0643
. [PMID: 37081693] - Amal Saad-Hussein, Wafaa Ghoneim Shousha, Sara Yahya Mohamed Al-Sadek, Shimaa Shawki Ramadan. Role of MTHFR 677C>T and 1298A>C gene polymorphisms on renal toxicity caused by lead exposure in wastewater treatment plant workers.
Environmental science and pollution research international.
2023 Jul; 30(35):84758-84764. doi:
10.1007/s11356-023-28309-y
. [PMID: 37369904] - Muhamad R Abdel Hammed, Mohammed A Tohamy, Sherly Z Boshra, Salma M Taha, Mostafa F M Saleh. Red cell distribution width is an inflammatory predictor marker of contrast induced nephropathy in patients undergoing percutaneous coronary intervention.
The Egyptian journal of immunology.
2023 Jul; 30(3):1-12. doi:
"
. [PMID: 37439452] - Jinny Jeffery, Helen Millar, Rachel Marrington, Finlay Mackenzie, Roanna George. Artificially raised creatinine concentrations due to analytical interference for samples contaminated with Total Parenteral Nutrition (TPN) fluid.
Annals of clinical biochemistry.
2023 Jun; ?(?):45632231186058. doi:
10.1177/00045632231186058
. [PMID: 37338174] - Yudan Mei, Xiaoyu Tong, Yumei Hu, Wenjun Liu, Jiajia Wang, Kaihong Lv, Xu Li, Liang Cao, Zhenzhong Wang, Wei Xiao, Xia Gao. Comparative pharmacokinetics of six bioactive components of Shen-Wu-Yi-Shen tablets in normal and chronic renal failure rats based on UPLC-TSQ-MS/MS.
Journal of ethnopharmacology.
2023 Jun; 317(?):116818. doi:
10.1016/j.jep.2023.116818
. [PMID: 37348793] - G Luo, H Liu, B Xie, Y Deng, P Xie, X Zhao, X Sun. [Therapeutic mechanism of Shenbing Decoction Ⅲ for renal fibrosis in chronic kidney disease: a study with network pharmacology, molecular docking and validation in rats].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2023 Jun; 43(6):924-934. doi:
10.12122/j.issn.1673-4254.2023.06.07
. [PMID: 37439164] - Yu-Jie Liu, Fu-Rong Li, Cai-Long Chen, Zhong-Xiao Wan, Jin-Si Chen, Jing Yang, Rong Liu, Jia-Ying Xu, Yan Zheng, Li-Qiang Qin, Guo-Chong Chen. Glomerular filtration rate estimated by differing measures and risk of all-cause mortality among Chinese individuals without or with diabetes: A nationwide prospective study.
Journal of diabetes.
2023 Jun; 15(6):508-518. doi:
10.1111/1753-0407.13393
. [PMID: 37128173] - Mohammad Pourahmadi, Mehran Fathi, Marzieh Rahimipour, Negar Shaterian, Hossein Kargar Jahromi. Hydroalcoholic Extract of Ziziphus Jujuba Leaf to Prevent Ethylene Glycol and Ammonium Chloride-Induced Kidney Stones in Male Rat: Is it Effective?.
Urology journal.
2023 May; ?(?):. doi:
10.22037/uj.v20i.7347
. [PMID: 37245086] - Xiu Chen, Jun Li, Liqiu Kou, Xiaolu Xie, Deqing Wei, Yaling Li. Efficacy and safety of long-acting cabotegravir versus oral tenofovir disoproxil fumarate-emtricitabine as HIV pre-exposure prophylaxis: A systematic review and meta-analysis.
Reviews in medical virology.
2023 May; ?(?):e2460. doi:
10.1002/rmv.2460
. [PMID: 37198721] - Pedro R Pereira, João Pereira, Patrícia C Braga, Sofia S Pereira, Mário Nora, Marta Guimarães, Mariana P Monteiro, Anabela Rodrigues. Renal Dysfunction Phenotypes in Patients Undergoing Obesity Surgery.
Biomolecules.
2023 May; 13(5):. doi:
10.3390/biom13050790
. [PMID: 37238660] - Ching-Kun Chang, Kuang-Hsi Chang, Wei-Chung Cheng, Po-Ku Chen, En-Pei Isabel Chiang, Shih-Hsin Chang, Yi-Chen Li, Chu-Huang Chen, Der-Yuan Chen. Lipid metabolomic signature might predict subclinical atherosclerosis in patients with active rheumatoid arthritis.
Clinical and experimental rheumatology.
2023 May; 41(5):1120-1128. doi:
10.55563/clinexprheumatol/int08c
. [PMID: 36200949] - - Arooj Jamshaid, - Abrar Ahmed, - Fatima Rasool, - Tehreem Waheed Rana, - Mirza Nouman Amjad Baig. Study of ameliorative effect of Allium cepa essential oil and purple cabbage (Brassica Oleracea Var. Capitata F. Rubra) leaves extract on CCl4 induced nephrotoxicity in rats.
Pakistan journal of pharmaceutical sciences.
2023 May; 36(3):765-771. doi:
"
. [PMID: 37580924] - Lifang Zheng, Ruiting Qin, Zhijian Rao, Weihua Xiao. High-intensity interval training induces renal injury and fibrosis in type 2 diabetic mice.
Life sciences.
2023 Apr; 324(?):121740. doi:
10.1016/j.lfs.2023.121740
. [PMID: 37120014] - Meltem Kumaş-Kulualp, Akçahan Gepdiremen, Ersin Karataş, Mukaddes Eşrefoğlu. Clemizole hydrochloride, a potent TRPC5 calcium channel inhibitor, prevents cisplatin-induced nephrotoxicity in Spraque-Dawley rats.
Journal of biochemical and molecular toxicology.
2023 Apr; ?(?):e23372. doi:
10.1002/jbt.23372
. [PMID: 37102204] - Heba M Eltahir, Hossein M Elbadawy, Ali Alalawi, Ahmed J Aldhafiri, Sabrin R M Ibrahim, Gamal A Mohamed, Abdel-Gawad S Shalkami, Mohannad A Almikhlafi, Muayad Albadrani, Yaser Alahmadi, Mekky M Abouzied, Maiiada H Nazmy. Alpha-Mangostin ameliorates acute kidney injury via modifying levels of circulating TNF-α and IL-6 in glycerol-induced rhabdomyolysis animal model.
Acta biochimica Polonica.
2023 04; ?(?):. doi:
10.18388/abp.2020_6509
. [PMID: 37068203] - Guo-Yi Tang, Sha Li, Yu Xu, Cheng Zhang, Xiao-Yu Xu, Lin Xu, Ning Wang, Yibin Feng. Renal herb formula protects against hyperuricemic nephropathy by inhibiting apoptosis and inflammation.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Apr; 116(?):154812. doi:
10.1016/j.phymed.2023.154812
. [PMID: 37167821] - Mahyar Khazaeli, Ane C F Nunes, Yitong Zhao, Mahziar Khazaali, John Prudente, Nosratola D Vaziri, Bhupinder Singh, Wei Ling Lau. Tetrahydrocurcumin Add-On therapy to losartan in a rat model of diabetic nephropathy decreases blood pressure and markers of kidney injury.
Pharmacology research & perspectives.
2023 Apr; 11(2):e01079. doi:
10.1002/prp2.1079
. [PMID: 36971089] - M A Abdelaziz, O M Ahmed, M Abdel-Gabbar, M R Mohammad, S R Ibrahim, M H Abdelzaher, A P Mohideen, S A Moawd, A I Geddawy. The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria.
European review for medical and pharmacological sciences.
2023 Apr; 27(8):3699-3713. doi:
10.26355/eurrev_202304_32169
. [PMID: 37140319] - Klaus Abraham, Katharina Penczynski, Bernhard H Monien, Nick Bergau, Sven Knüppel, Cornelia Weikert. Risks of misinterpretation of biomarker measurements in spot urine adjusted for creatinine - A problem especially for studies comparing plant based with omnivorous diets.
International journal of hygiene and environmental health.
2023 04; 249(?):114142. doi:
10.1016/j.ijheh.2023.114142
. [PMID: 36842230] - Wenfu Cao, Li Liu, Jilin Peng, Ying Li, Jing Tian, Dashuang Gong. Effects of Shenkang Decoction on Creatinine and Blood Urea Nitrogen in Chronic Renal Failure Hemodialysis Patients: A Randomized Controlled Trial.
Journal of integrative and complementary medicine.
2023 Mar; ?(?):. doi:
10.1089/jicm.2022.0587
. [PMID: 36944133] - Ester Zamarrón, Ana Jaureguizar, Aldara García-Sánchez, Trinidad Díaz-Cambriles, Alberto Alonso-Fernández, Vanesa Lores, Olga Mediano, Fernanda Troncoso-Acevedo, Sheila Cabello-Pelegrín, Enrique Morales-Ruíz, María T Ramírez-Prieto, María Isabel Valiente-Díaz, Teresa Gómez-García, Raquel Casitas, Elisabet Martínez-Cerón, Raúl Galera, Carolina Cubillos-Zapata, Francisco García-Río. Continuous Positive Airway Pressure Effect on Albuminuria Progression in Patients with Obstructive Sleep Apnea and Diabetic Kidney Disease: A Randomized Clinical Trial.
American journal of respiratory and critical care medicine.
2023 03; 207(6):757-767. doi:
10.1164/rccm.202206-1091oc
. [PMID: 36342964] - Xiang-Rong Cheng, Jia-Hui Ma, Issoufou Amadou, Wei Zhao, Yu-Yao Chen, Chen-Xi Zhang, Bin Guan. Electrophilic components from Xiaoheiyao (rhizomes of Inula nervosa Wall.) alleviate the production of heterocyclic aromatic amines via creatinine inhibition.
Food chemistry.
2023 Mar; 404(Pt A):134561. doi:
10.1016/j.foodchem.2022.134561
. [PMID: 36252379] - Doa'a G F Al-U'datt, Carole C Tranchant, Muhammad Alu'datt, Sara Abusara, Ahmed Al-Dwairi, Mohammad AlQudah, Othman Al-Shboul, Roddy Hiram, Yasemin Altuntas, Saied Jaradat, Karem H Alzoubi. Inhibition of transglutaminase 2 (TG2) ameliorates ventricular fibrosis in isoproterenol-induced heart failure in rats.
Life sciences.
2023 Mar; 321(?):121564. doi:
10.1016/j.lfs.2023.121564
. [PMID: 36931499] - Ishfaq Ahmad Rather, Nadeem Khan, Ajay Singh Kushwah, Gurunath Surampalli, Manish Kumar. Nephroprotective effects of honokiol in a high-fat diet-streptozotocin rat model of diabetic nephropathy.
Life sciences.
2023 Mar; ?(?):121543. doi:
10.1016/j.lfs.2023.121543
. [PMID: 36871934] - Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang. The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways.
European journal of histochemistry : EJH.
2023 Mar; 67(1):. doi:
10.4081/ejh.2023.3648
. [PMID: 36856315] - Xiao-Xin Chen, Zuo-Xi Chen, Wu-Jie Zhou, Yong Wang, Jia Su, Qiang Zhou. Blood urea nitrogen to creatinine ratio is associated with physical frailty in older-aged Chinese: a cross-sectional study.
Aging clinical and experimental research.
2023 Mar; 35(3):581-589. doi:
10.1007/s40520-022-02332-4
. [PMID: 36629995] - Zhong Li, ZhiQin Yang, MeiXue Ji. Potential benefits and related treatment effects of calcineurin inhibitors combined with steroid for IgA nephropathy: a systematic review and meta-analysis.
International urology and nephrology.
2023 Mar; ?(?):. doi:
10.1007/s11255-023-03524-1
. [PMID: 36856924] - Chuang Chen, Shuangshuang Ma, Lyuzhao Liao, Yu Xiao, Haiwen Dai. Effects of mesenchymal stem cells on post-resuscitation renal and intestinal injuries in a porcine cardiac arrest model.
Shock (Augusta, Ga.).
2023 Mar; ?(?):. doi:
10.1097/shk.0000000000002107
. [PMID: 36852976] - Benjamin Lidgard, Andrew N Hoofnagle, Leila R Zelnick, Ian H de Boer, Amanda M Fretts, Bryan R Kestenbaum, Rozenn N Lemaitre, Cassianne Robinson-Cohen, Nisha Bansal. High-Density Lipoprotein Lipidomics in Chronic Kidney Disease.
Clinical chemistry.
2023 03; 69(3):273-282. doi:
10.1093/clinchem/hvac216
. [PMID: 36644946]