Methandriol (BioDeep_00000858690)

   


代谢物信息卡片


Methandriol

化学式: C20H32O2 (304.2402)
中文名称: 美雄醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CCC(CC1=CCC3C2CCC4(C3CCC4(C)O)C)O
InChI: InChI=1S/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h4,14-17,21-22H,5-12H2,1-3H3/t14-,15+,16-,17-,18-,19-,20-/m0/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid

同义名列表

2 个代谢物同义名

Methandriol; Methandriol



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ALB, AR, DMD, MTPN, PTP4A2
Peripheral membrane protein 2 CYP11B1, DMD
Endoplasmic reticulum membrane 2 CYP11B1, HSP90B1
Nucleus 6 ALB, AR, DMD, HSP90B1, MTPN, PTP4A2
cytosol 6 ALB, AR, DMD, HSP90B1, MTPN, PTP4A2
centrosome 1 ALB
nucleoplasm 1 AR
Cytoplasmic side 1 DMD
Synapse 1 DMD
cell surface 2 DMD, PLAU
Golgi apparatus 2 ALB, SERPINA1
Golgi membrane 1 INS
mitochondrial inner membrane 1 CYP11B1
sarcolemma 1 DMD
smooth endoplasmic reticulum 1 HSP90B1
plasma membrane 7 AR, DMD, F2, PLAU, PTP4A2, REN, SERPINC1
Membrane 4 AR, DMD, HSP90B1, REN
axon 1 MTPN
extracellular exosome 6 ALB, F2, HSP90B1, PLAU, SERPINA1, SERPINC1
endoplasmic reticulum 3 ALB, HSP90B1, SERPINA1
extracellular space 9 ALB, F2, GH1, GNRH1, INS, PLAU, REN, SERPINA1, SERPINC1
perinuclear region of cytoplasm 2 HSP90B1, MTPN
mitochondrion 2 CYP11B1, FDX1
protein-containing complex 4 ALB, AR, DMD, HSP90B1
intracellular membrane-bounded organelle 1 SERPINA1
filopodium 1 DMD
Secreted 7 ALB, F2, GH1, INS, PLAU, PRB1, REN
extracellular region 11 ALB, F2, GH1, GNRH1, HSP90B1, INS, PLAU, PRB1, REN, SERPINA1, SERPINC1
Mitochondrion matrix 1 FDX1
mitochondrial matrix 1 FDX1
anchoring junction 1 ALB
external side of plasma membrane 1 PLAU
Z disc 1 DMD
midbody 1 HSP90B1
Early endosome 1 PTP4A2
apical part of cell 1 REN
COPII-coated ER to Golgi transport vesicle 1 SERPINA1
postsynaptic membrane 1 DMD
Cell membrane, sarcolemma 1 DMD
Cytoplasm, perinuclear region 1 MTPN
Mitochondrion inner membrane 1 CYP11B1
Membrane raft 1 DMD
Cytoplasm, cytoskeleton 1 DMD
focal adhesion 2 HSP90B1, PLAU
collagen-containing extracellular matrix 4 F2, HSP90B1, SERPINA1, SERPINC1
nuclear speck 1 AR
Nucleus outer membrane 1 DMD
nuclear outer membrane 1 DMD
Postsynaptic cell membrane 1 DMD
ciliary basal body 1 ALB
chromatin 1 AR
cytoskeleton 1 DMD
centriole 1 ALB
Secreted, extracellular space 1 SERPINC1
spindle pole 1 ALB
blood microparticle 3 ALB, F2, SERPINC1
endosome lumen 2 GH1, INS
specific granule membrane 1 PLAU
tertiary granule membrane 1 PLAU
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
filopodium membrane 1 DMD
ficolin-1-rich granule lumen 1 SERPINA1
secretory granule lumen 1 INS
Golgi lumen 2 F2, INS
endoplasmic reticulum lumen 6 ALB, F2, HSP90B1, INS, SERPINA1, SERPINC1
platelet alpha granule lumen 2 ALB, SERPINA1
transport vesicle 1 INS
serine-type endopeptidase complex 1 PLAU
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 INS, SERPINA1
Single-pass type IV membrane protein 1 DMD
Sarcoplasmic reticulum lumen 1 HSP90B1
costamere 1 DMD
dystrophin-associated glycoprotein complex 1 DMD
serine protease inhibitor complex 1 PLAU
cell-substrate junction 1 DMD
endocytic vesicle lumen 1 HSP90B1
protein complex involved in cell-matrix adhesion 1 PLAU
growth hormone receptor complex 1 GH1
endoplasmic reticulum chaperone complex 1 HSP90B1
neuron projection terminus 1 DMD
syntrophin complex 1 DMD
F-actin capping protein complex 1 MTPN
ciliary transition fiber 1 ALB
organelle 1 DMD
plasma membrane bounded cell projection 1 DMD


文献列表

  • Wei Liu, Lan Zhang, Liangbiao Fan, Zian Lin, Yimin Cai, Zhenyi Wei, Guonan Chen. An improved hollow fiber solvent-stir bar microextraction for the preconcentration of anabolic steroids in biological matrix with determination by gas chromatography-mass spectrometry. Journal of chromatography. A. 2012 Apr; 1233(?):1-7. doi: 10.1016/j.chroma.2012.01.064. [PMID: 22386059]
  • Masayuki Yamada, Sugako Aramaki, Masahiko Kurosawa, Isao Kijima-Suda, Koichi Saito, Hiroyuki Nakazawa. Simultaneous doping analysis of main urinary metabolites of anabolic steroids in horse by ion-trap gas chromatography-tandem mass spectrometry. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2008 Sep; 24(9):1199-204. doi: 10.2116/analsci.24.1199. [PMID: 18781036]
  • Lan Zhang, Jinfeng Chen, Ping Tong, Tianlin Li. [Simultaneous analysis of ten anabolic steroids in blood plasma using high performance liquid chromatography]. Se pu = Chinese journal of chromatography. 2008 Jul; 26(4):449-53. doi: NULL. [PMID: 18959240]
  • Masayuki Yamada, Sugako Aramaki, Masahiko Kurosawa, Koichi Saito, Hiroyuki Nakazawa. Detection of urinary metabolites common to structurally related 17alpha-alkyl anabolic steroids in horses and application to doping tests in racehorses: methandienone, methandriol, and oxymetholone. Journal of analytical toxicology. 2008 Jun; 32(5):387-91. doi: 10.1093/jat/32.5.387. [PMID: 18544225]
  • J Kokkonen, A Leinonen, J Tuominen, T Seppälä. Comparison of sensitivity between gas chromatography-low-resolution mass spectrometry and gas chromatography-high-resolution mass spectrometry for determining metandienone metabolites in urine. Journal of chromatography. B, Biomedical sciences and applications. 1999 Nov; 734(2):179-89. doi: 10.1016/s0378-4347(99)00317-5. [PMID: 10595716]
  • L Leyssens, M Van Puymbroeck, J Raus. Interference of Helix pomatia extracts on the determination of methandriol in veterinary residue control analysis. The Analyst. 1998 Dec; 123(12):2643-4. doi: 10.1039/a805018j. [PMID: 10435316]
  • J E Turner, C H Irvine. Effect of prolonged administration of anabolic and androgenic steroids on reproductive function in the mare. Journal of reproduction and fertility. Supplement. 1982; 32(?):213-8. doi: . [PMID: 6762438]
  • S A Tuzhilin, M Gonda, G Carbonell, D A Dreiling. Serum amylases and their inhibitors: 2. Clinical and experimental +obersvations--diet and steroid effects. The American journal of gastroenterology. 1982 Jan; 77(1):26-8. doi: NULL. [PMID: 6175206]
  • A Molteni, P A Nickerson, A C Brownie, K Liu. Effect on an ergoline derivate-nicergoline (Sermion) on methylandrostenediol-induced hypertension in the rat. Archives internationales de pharmacodynamie et de therapie. 1980 Sep; 247(1):119-34. doi: . [PMID: 7447555]
  • G M Rendina, D Patrono. The use of a biological preparation in the treatment of some gynaecological diseases. Current medical research and opinion. 1976; 4(2):151-7. doi: 10.1185/03007997609109296. [PMID: 776538]
  • I D Walker, J F Davidson, P Young, J A Conkie. Effect of anabolic steroids on plasma antithrombin III. alpha2 macroglobulin and alpha1 antitrypsin levels. Thrombosis et diathesis haemorrhagica. 1975 Sep; 34(1):106-14. doi: . [PMID: 52896]
  • A STOLK. INFLUENCE OF ADMINISTRATION OF METHYLANDROSTENEDIOL ON ELECTROPHEROGRAM OF SERUM PROTEINS IN C3HF VIRGIN MICE WITH EXPERIMENTAL MAMMARY CARCINOMA. Acta morphologica Neerlando-Scandinavica. 1964; 5(?):295-301. doi: . [PMID: 14121943]
  • L SUARDI. [Influence of the administration of testosterone, methylandrostenediol and 19-nortestosterone on urinary elimination of estrogens and corticoids]. Minerva medica. 1959 Oct; 50(?):3407-12. doi: . [PMID: 13835496]
  • H ARKO, U K RINNE. The kidney and adrenal cortex of the methylandrostenediol treated rat: histological and histochemical observations. Annales medicinae experimentalis et biologiae Fenniae. 1958; 36(3):328-34. doi: NULL. [PMID: 13595349]
  • E SALGADO, H SELYE. Hormonal factors in the production of experimental renal and cardiovascular disease; synergism between somatotrophic hormone and methylandrostenediol. The Journal of laboratory and clinical medicine. 1955 Feb; 45(2):237-46. doi: NULL. [PMID: 13233650]
  • E SALGADO, H SELYE. The role of the thyroid in the production of cardiovascular and renal changes by methylandrostenediol. The Journal of endocrinology. 1954 Nov; 11(4):331-7. doi: 10.1677/joe.0.0110331. [PMID: 13211892]
  • E SALDAGO, H SELYE. The role of the adrenals in the production of cardiovascular and renal changes by methylandrostenediol. Archives internationales de physiologie et de biochimie. 1954 Sep; 62(3):352-8. doi: NULL. [PMID: 13218802]
  • F DE MATTEIS, M GALASSI, S SCARABICCHI. [Nephrotropic effect of methylandrostenediol; experimental studies on intact and castrated rat]. Folia endocrinologica; mensile di incretologia e incretoterapia. 1954 Jun; 7(3):267-92. doi: NULL. [PMID: 13200593]
  • F R SKELTON. The production of hypertension, nephrosclerosis and cardiac lesions by methylandrostenediol treatment in the rat. Endocrinology. 1953 Nov; 53(5):492-505. doi: 10.1210/endo-53-5-492. [PMID: 13107625]
  • R HENRY, A NETTER, J MICHALLAND. [Effect of methylandrostenediol dipropionate on urinary gonadotropins in menopause; difference according to route of administration]. Annales d'endocrinologie. 1952; 13(6):954-8. doi: NULL. [PMID: 13031226]