Bicozamycin (BioDeep_00000008567)

   


代谢物信息卡片


Bicyclomycin

化学式: C12H18N2O7 (302.1114)
中文名称: 双环霉素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C1CCOC2(C(O)C(C)(O)CO)NC(=O)C1(O)NC2=O
InChI: InChI=1S/C12H18N2O7/c1-6-3-4-21-12(7(16)10(2,19)5-15)9(18)13-11(6,20)8(17)14-12/h7,15-16,19-20H,1,3-5H2,2H3,(H,13,18)(H,14,17)/t7-,10-,11+,12-/m0/s1

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D005765 - Gastrointestinal Agents > D000930 - Antidiarrheals
C784 - Protein Synthesis Inhibitor
D004791 - Enzyme Inhibitors

同义名列表

3 个代谢物同义名

Bicyclomycin; Bicozamycin; Bicozamycin



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ALB, HSP90AA2P, IDO1, SLC9A1
Peripheral membrane protein 1 CYP27A1
Mitochondrion membrane 1 CYP27A1
Nucleus 3 ALB, GEN1, PNKD
cytosol 4 ALB, HSP90AA2P, IDO1, MAT1A
centrosome 2 ALB, GEN1
nucleoplasm 3 ATP2B1, GEN1, SLC9A1
Cell membrane 3 ATP2B1, AVPR1B, SLC9A1
lamellipodium 1 SLC9A1
Multi-pass membrane protein 3 ATP2B1, AVPR1B, SLC9A1
Synapse 1 ATP2B1
cell surface 1 SLC9A1
glutamatergic synapse 1 ATP2B1
Golgi apparatus 2 ALB, AVPR1B
mitochondrial inner membrane 3 ATP5ME, CYP27A1, OTC
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 IDO1
endosome 1 AVPR1B
plasma membrane 5 ATP2B1, AVPR1B, HSP90AA2P, PRSS27, SLC9A1
synaptic vesicle membrane 1 ATP2B1
Membrane 3 ATP2B1, PNKD, SLC9A1
apical plasma membrane 1 SLC9A1
basolateral plasma membrane 2 ATP2B1, SLC9A1
extracellular exosome 4 ALB, ATP2B1, HSP90AA2P, SLC9A1
endoplasmic reticulum 1 ALB
extracellular space 2 ALB, IFNG
perinuclear region of cytoplasm 2 HSP90AA2P, SLC9A1
intercalated disc 1 SLC9A1
mitochondrion 5 ATP5ME, CYP27A1, OTC, PNKD, SLC9A1
protein-containing complex 2 ALB, HSP90AA2P
intracellular membrane-bounded organelle 1 ATP2B1
Secreted 2 ALB, IFNG
extracellular region 3 ALB, IFNG, PRSS27
Mitochondrion matrix 1 OTC
mitochondrial matrix 2 CYP27A1, OTC
anchoring junction 1 ALB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
T-tubule 1 SLC9A1
Mitochondrion inner membrane 1 CYP27A1
Membrane raft 1 SLC9A1
focal adhesion 1 SLC9A1
lateral plasma membrane 1 ATP2B1
ciliary basal body 1 ALB
stereocilium bundle 1 IDO1
cell projection 1 ATP2B1
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 2 ATP2B1, SLC9A1
Presynaptic cell membrane 1 ATP2B1
endoplasmic reticulum lumen 1 ALB
platelet alpha granule lumen 1 ALB
immunological synapse 1 ATP2B1
presynaptic cytosol 1 PNKD
proton-transporting ATP synthase complex 1 ATP5ME
proton-transporting ATP synthase complex, coupling factor F(o) 1 ATP5ME
photoreceptor ribbon synapse 1 ATP2B1
smooth muscle contractile fiber 1 IDO1
cation-transporting ATPase complex 1 SLC9A1
methionine adenosyltransferase complex 1 MAT1A
ciliary transition fiber 1 ALB


文献列表

  • N Misawa, M Sueyoshi, R Uemura, Y Kakemizu, K Kawashima, H Nagatomo, F Kondo, T Murakami, Y Takahashi. Effect of bicozamycin on the eradication of Shiga toxin-producing Escherichia coli in calves. Microbiology and immunology. 2000; 44(11):891-6. doi: 10.1111/j.1348-0421.2000.tb02580.x. [PMID: 11145269]
  • H Yoshimura, S Hamamoto, Y Ishihara. Plasma concentrations and tissue residues of bicozamycin given orally to pigs. Veterinary research communications. 1995; 19(3):215-20. doi: 10.1007/bf01839300. [PMID: 7571395]
  • O O Barriga. Depression of cell-mediated immunity following inoculation of Trichinella spiralis extract in the mouse. Immunology. 1978 Jan; 34(1):167-73. doi: NULL. [PMID: 23994]