d-Corlin (BioDeep_00000855583)

   


代谢物信息卡片


Prednisone acetate

化学式: C23H28O6 (400.1886)
中文名称: 醋酸泼尼松
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)C=CC34C)C)O
InChI: InChI=1S/C23H28O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h6,8,10,16-17,20,28H,4-5,7,9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1

描述信息

同义名列表

3 个代谢物同义名

Prednisone acetate; d-Corlin; Cortancyl



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 FOXP3, MARVELD1, POMC, RBPJ, TGFB1
Peripheral membrane protein 1 MBP
Endoplasmic reticulum membrane 1 CD4
Nucleus 7 ACR, FOXP3, MARVELD1, MBP, PCNA, RBPJ, TGFB1
cytosol 2 FOXP3, MBP
nuclear body 1 PCNA
centrosome 1 PCNA
nucleoplasm 3 FOXP3, PCNA, RBPJ
Cell membrane 4 CD4, DLL4, MARVELD1, TNF
Cytoplasmic side 1 MBP
Multi-pass membrane protein 2 MARVELD1, MOG
Synapse 1 MBP
cell surface 3 MBP, TGFB1, TNF
neuronal cell body 3 MBP, TGFB1, TNF
plasma membrane 9 CD4, DLL3, DLL4, IFNLR1, MARVELD1, MBP, MOG, TGFB1, TNF
Membrane 5 DLL3, DLL4, IFNLR1, MARVELD1, MOG
axon 1 TGFB1
extracellular exosome 2 MBP, PCNA
extracellular space 9 CRP, CXCL8, IL10, IL17A, IL4, IL6, POMC, TGFB1, TNF
protein-containing complex 3 ACR, FOXP3, MBP
Single-pass type I membrane protein 5 CD4, DLL3, DLL4, IFNLR1, MOG
Secreted 8 CRP, CXCL8, IL10, IL17A, IL4, IL6, POMC, TGFB1
extracellular region 11 ACR, CRP, CXCL8, IL10, IL17A, IL4, IL6, MBP, POMC, TGFB1, TNF
external side of plasma membrane 4 CD4, IL17A, MOG, TNF
Secreted, extracellular space, extracellular matrix 1 TGFB1
nucleolus 1 RBPJ
Early endosome 1 CD4
Golgi-associated vesicle 1 ACR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 CD4, TNF
Cytoplasm, cytoskeleton 1 MARVELD1
extracellular matrix 1 TGFB1
collagen-containing extracellular matrix 2 MBP, TGFB1
secretory granule 2 POMC, TGFB1
chromatin 3 FOXP3, PCNA, RBPJ
phagocytic cup 1 TNF
cell periphery 1 MBP
cytoskeleton 1 MARVELD1
[Isoform 3]: Nucleus 1 MBP
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
blood microparticle 1 TGFB1
[Isoform 2]: Cell membrane 1 MOG
replication fork 1 PCNA
myelin sheath 1 MBP
ficolin-1-rich granule lumen 1 MBP
secretory granule lumen 1 POMC
Golgi lumen 1 TGFB1
endoplasmic reticulum lumen 2 CD4, IL6
transcription repressor complex 1 RBPJ
male germ cell nucleus 1 PCNA
platelet alpha granule lumen 1 TGFB1
transport vesicle 1 MBP
nuclear lamina 1 PCNA
clathrin-coated endocytic vesicle membrane 1 CD4
[Isoform 1]: Cell membrane 1 MOG
[Isoform 3]: Cell membrane 1 MOG
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix 1 TGFB1
[Transforming growth factor beta-1]: Secreted 1 TGFB1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
compact myelin 1 MBP
internode region of axon 1 MBP
interleukin-6 receptor complex 1 IL6
[Isoform 6]: Cell membrane 1 MOG
[Isoform 7]: Cell membrane 1 MOG
acrosomal matrix 1 ACR
[Isoform 4]: Cell membrane 1 MOG
[Isoform 5]: Cell membrane 1 MOG
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
[Isoform 8]: Cell membrane 1 MOG
[Bone marrow proteoglycan]: Secreted 1 MBP
MAML1-RBP-Jkappa- ICN1 complex 1 RBPJ
Myelin membrane 1 MBP
interleukin-28 receptor complex 1 IFNLR1
[Isoform 9]: Cell membrane 1 MOG
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Huaying Fan, Mingyan Yang, Xin Che, Ziliang Zhang, Hui Xu, Ke Liu, Qinggang Meng. Activity study of a hydroxynaphthoquinone fraction from Arnebia euchroma in experimental arthritis. Fitoterapia. 2012 Oct; 83(7):1226-37. doi: 10.1016/j.fitote.2012.06.011. [PMID: 22735599]
  • Yan Liu, Hui Zhao, Jie Zhang, Ping Zhang, Ming Li, Fang Qi, Yizhou Wang, Shuang Kou, Qi Zheng, Lei Wang. The regulatory effect of liuwei dihuang pills on cytokines in mice with experimental autoimmune encephalomyelitis. The American journal of Chinese medicine. 2012; 40(2):295-308. doi: 10.1142/s0192415x12500231. [PMID: 22419424]
  • Jian-hua Zhu, Yong-liang Hu, Wu Zhang, Wei Guan, Guang-zhao Huang. [Effects of triptolide on hypothalamic-pituitary-adrenal axis of rats]. Fa yi xue za zhi. 2010 Aug; 26(4):260-5. doi: . [PMID: 20967951]
  • Kyunga Na, Jaeyeon Jung, Jonghwan Lee, Jinho Hyun. Thermoresponsive pore structure of biopolymer microspheres for a smart drug carrier. Langmuir : the ACS journal of surfaces and colloids. 2010 Jul; 26(13):11165-9. doi: 10.1021/la1013285. [PMID: 20550167]
  • Lei Wang, Hui Zhao, Yong-ping Fan, Hai-yang Gong, Ming Li, Fang Qi, Yan Liu. Research on the mechanism of Zuogui Pill and Yougui Pill in promoting axonal regeneration in model rats of autoimmune encephalomyelitis. Chinese journal of integrative medicine. 2010 Apr; 16(2):167-72. doi: 10.1007/s11655-010-0167-z. [PMID: 20473744]
  • Rui Xia, Baoquan Che, Zhe Zhang. [Simultaneous identification of fifteen glucocorticoids in Chinese traditional medicine preparations by liquid chromatography-mass spectrometry]. Se pu = Chinese journal of chromatography. 2007 Nov; 25(6):926-9. doi: . [PMID: 18257318]
  • Puwei Yuan, Xijing He, Haizhe Zhou, Guoyu Wang, Dong Wang, Haopeng Li. Experimental study on gufusheng in treatment of steroid-induced ischemic necrosis of femoral head in rabbits. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2005 Dec; 25(4):300-3. doi: . [PMID: 16447676]
  • Wei-ming Tian, Wen-zhi Wang, Xin-guo Wang, Guo-hua Xu. [Effect of gufuhuo decoction on local apoptosis of steroid-induced necrosis of femoral head]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Dec; 30(23):1848-51. doi: . [PMID: 16499025]
  • Wen-ling Wang, You-ming Su, Rong-ya Yang, Jie Zhang, Yang Xu. Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu decoction. Chinese journal of integrative medicine. 2005 Mar; 11(1):34-6. doi: 10.1007/bf02835746. [PMID: 15975305]
  • Yanping Chen, Keqin Huang, Fengping Lang, Yongxun Huang, Hui Huang, Hong Huang, Chongguang Zhou, Wanqiang Zhang. Experimental study on cheng zai wan for treatment of necrosis of the femoral head. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2003 Dec; 23(4):292-8. doi: ". [PMID: 14719304]
  • Wei-ming Tian, Wen-zhi Wang, Xin-guo Wang. [Effect of gufuhuotang on hemorheology and lipid metabolism of hormonal necrosis of femoral head]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2002 Oct; 27(10):769-71. doi: NULL. [PMID: 12776560]
  • X Y Liu, Y Sun. [Clinical and experimental study on multiple sclerosis with bushen gusui tablet]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 2001 Jan; 21(1):10-4. doi: . [PMID: 12577368]
  • J Cole, D Ertoy, H Lin, R L Sutliff, E Ezan, T T Guyene, M Capecchi, P Corvol, K E Bernstein. Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice. The Journal of clinical investigation. 2000 Dec; 106(11):1391-8. doi: 10.1172/jci10557. [PMID: 11104792]