Davidigenin (BioDeep_00000007498)
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C15H14O4 (258.0892)
中文名称: 2,4-二羟基-3-(p-羟基苯基)-苯丙酮
谱图信息:
最多检出来源 Astragalus membranaceus(otcml) 66.67%
分子结构信息
SMILES: C1(O)C=CC(C(=O)CCC2C=CC(O)=CC=2)=C(O)C=1
InChI: InChI=1S/C15H14O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-2,4-7,9,16-17,19H,3,8H2
描述信息
A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2, and 4 respectively.
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:27655
- KEGG: C09618
- PubChem: 442342
- Metlin: METLIN52255
- ChEMBL: CHEMBL192877
- LipidMAPS: LMPK12120452
- KNApSAcK: C00007926
- CAS: 23130-26-9
- PMhub: MS000020878
- Flavonoid: FL1D1ANS0001
- MetaboLights: MTBLC27655
- PubChem: 11809
- 3DMET: B03134
- NIKKAJI: J23.023E
- LOTUS: LTS0131344
- KNApSAcK: 27655
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
21 个相关的物种来源信息
- 4206 - Adoxaceae: LTS0131344
- 4056 - Apocynaceae: LTS0131344
- 4219 - Artemisia: LTS0131344
- 72341 - Artemisia dracunculus: 10.1016/J.PHYTOCHEM.2006.05.015
- 72341 - Artemisia dracunculus: LTS0131344
- 4210 - Asteraceae: LTS0131344
- 2759 - Eukaryota: LTS0131344
- 164493 - Fadogia: LTS0131344
- 164500 - Fadogia ancylantha: 10.1021/NP900466X
- 164500 - Fadogia ancylantha: LTS0131344
- 3398 - Magnoliopsida: LTS0131344
- 69382 - Mascarenhasia: LTS0131344
- 69383 - Mascarenhasia arborescens: 10.1016/J.JEP.2010.05.017
- 69383 - Mascarenhasia arborescens: LTS0131344
- 24966 - Rubiaceae: LTS0131344
- 35493 - Streptophyta: LTS0131344
- 58023 - Tracheophyta: LTS0131344
- 4204 - Viburnum: LTS0131344
- 237932 - Viburnum davidii: 10.1016/0031-9422(77)80128-3
- 237932 - Viburnum davidii: LTS0131344
- 33090 - Viridiplantae: LTS0131344
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Li Zhen, Shuyue He, Qingwang Xue, Yaping Liu, Jianxin Cao, Tianrui Zhao, Guiguang Cheng, Yudan Wang. Influence of Ultra-High-Pressure Pretreatment Method on Chemical Constituents, Antioxidant and Cytoprotective Activities of Free, Esterified, and Bound Phenolics from Anneslea Fragrans Wall. Leaves.
Plant foods for human nutrition (Dordrecht, Netherlands).
2023 Jun; ?(?):. doi:
10.1007/s11130-023-01071-9
. [PMID: 37266882] - Hung-Yi Huang, Horng-Huey Ko, Yu-Jin Jin, Sheng-Zehn Yang, You-An Shih, Ih-Sheng Chen. Dihydrochalcone glucosides and antioxidant activity from the roots of Anneslea fragrans var. lanceolata.
Phytochemistry.
2012 Jun; 78(?):120-5. doi:
10.1016/j.phytochem.2012.02.023
. [PMID: 22459967] - Ming Wang, Hui Zhao, Xiu-Ling Wang, Hong-Lei Zhang, Qing-Hong Hao. [C-ring cleavage of liquiritigenin extracted from licorice roots by an oxygen-tolerant bovine rumen bacterium strain Aeroto-Niu-O16].
Yao xue xue bao = Acta pharmaceutica Sinica.
2012 May; 47(5):664-9. doi:
. [PMID: 22812014]
- Sasha W Eisenman, Alexander Poulev, Lena Struwe, Ilya Raskin, David M Ribnicky. Qualitative variation of anti-diabetic compounds in different tarragon (Artemisia dracunculus L.) cytotypes.
Fitoterapia.
2011 Oct; 82(7):1062-74. doi:
10.1016/j.fitote.2011.07.003
. [PMID: 21798321] - Odile Desire, Céline Rivière, René Razafindrazaka, Laurence Goossens, Stéphane Moreau, Jean Guillon, Suzanne Uverg-Ratsimamanga, Pascal Andriamadio, Nicholas Moore, Adolphe Randriantsoa, Amélie Raharisololalao. Antispasmodic and antioxidant activities of fractions and bioactive constituent davidigenin isolated from Mascarenhasia arborescens.
Journal of ethnopharmacology.
2010 Jul; 130(2):320-8. doi:
10.1016/j.jep.2010.05.017
. [PMID: 20580662] - Teresa Mencherini, Patrizia Picerno, Pasquale Del Gaudio, Michela Festa, Anna Capasso, Rita Aquino. Saponins and polyphenols from Fadogia ancylantha (makoni tea).
Journal of natural products.
2010 Feb; 73(2):247-51. doi:
10.1021/np900466x
. [PMID: 20058934] - Sithes Logendra, David M Ribnicky, Hui Yang, Alexander Poulev, Jun Ma, Edward J Kennelly, Ilya Raskin. Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus.
Phytochemistry.
2006 Jul; 67(14):1539-46. doi:
10.1016/j.phytochem.2006.05.015
. [PMID: 16806328] - Liqin Zhao, Roberta D Brinton. Structure-based virtual screening for plant-based ERbeta-selective ligands as potential preventative therapy against age-related neurodegenerative diseases.
Journal of medicinal chemistry.
2005 May; 48(10):3463-6. doi:
10.1021/jm0490538
. [PMID: 15887952] - Ana M Madureira, Annamária Molnár, Pedro M Abreu, Joseph Molnár, Maria-José U Ferreira. A new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of P-glycoprotein.
Planta medica.
2004 Sep; 70(9):828-33. doi:
10.1055/s-2004-827231
. [PMID: 15503353] - Takayuki Asano, Kazuhisa Ishihara, Takashi Morota, Shuichi Takeda, Masaki Aburada. Permeability of the flavonoids liquiritigenin and its glycosides in licorice roots and davidigenin, a hydrogenated metabolite of liquiritigenin, using human intestinal cell line Caco-2.
Journal of ethnopharmacology.
2003 Dec; 89(2-3):285-9. doi:
10.1016/j.jep.2003.09.009
. [PMID: 14611893] - Zhen-Li Liu, Sachiko Tanaka, Hiroshi Horigome, Toshihiko Hirano, Kitaro Oka. Induction of apoptosis in human lung fibroblasts and peripheral lymphocytes in vitro by Shosaiko-to derived phenolic metabolites.
Biological & pharmaceutical bulletin.
2002 Jan; 25(1):37-41. doi:
10.1248/bpb.25.37
. [PMID: 11824553] - T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1975 Jul; 71(5):457-62. doi:
. [PMID: 280]