Classification Term: 167968

二氢查耳酮 (ontology term: a74db26e164a7ce6204e04ee99f53199)

二氢查耳酮

found 137 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: 黄酮类

Child Taxonomies: There is no child term of current ontology term.

Phlorizin

1-{6-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydr opyran-2-yloxy)]-2,4-dihydroxyphenyl}-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.1369404)


Phlorizin, also known as phlorizoside or phlorrhizen, belongs to the class of organic compounds known as flavonoid o-glycosides. Flavonoid O-glycosides are compounds containing a carbohydrate moiety which is O-glycosidically linked to the 2-phenylchromen-4-one flavonoid backbone. Phlorizin (also referred to as phloridzin; chemical name phloretin-2-‚âà√≠‚Äö√¢¬ß-D-glucopyranoside) is a glucoside of phloretin, a dihydrochalcone, a family of bicyclic flavonoids, which in turn is a subgroup in the diverse phenylpropanoid synthesis pathway in plants. In humans, phlorizin is involved in lactose degradation. Phlorizin is a bitter tasting compound. phlorizin is found, on average, in the highest concentration in a few different foods, such as mexican oregano, european plums, and apples and in a lower concentration in pomegranates and apricots. phlorizin has also been detected, but not quantified, in several different foods, such as epazotes, durians, chinese broccoli, sesames, and sweet potato. This could make phlorizin a potential biomarker for the consumption of these foods. It is of sweet taste and contains four molecules of water in the crystal. Phlorizin is found primarily in unripe Malus (apple), root bark of apple, trace amounts have been found in strawberry. It is poorly soluble in ether and cold water, but soluble in ethanol and hot water. Closely related species, such as pear (Pyrus communis), cherry, and other fruit trees in the Rosaceae do not contain phloridzin. Phlorizin was studied as a potential pharmaceutical treatment for type 2 diabetes, but has since been superseded by more selective and more promising synthetic analogs, such as empagliflozin, canagliflozin and dapagliflozin. Phlorizin is a competitive inhibitor of SGLT1 and SGLT2 because it competes with D-glucose for binding to the carrier; this reduces renal glucose transport, lowering the amount of glucose in the blood. Phlorizin is not an effective drug because when orally consumed, it is nearly entirely converted into phloretin by hydrolytic enzymes in the small intestine. Above 200 °C, it decomposes. Phlorizin is an aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. It has a role as a plant metabolite and an antioxidant. It is an aryl beta-D-glucoside, a member of dihydrochalcones and a monosaccharide derivative. It is functionally related to a phloretin. Phlorizin is a natural product found in Malus doumeri, Vaccinium macrocarpon, and other organisms with data available. See also: ... View More ... An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. Isolated from apple leaves and bark Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin (Floridzin) is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.

   

Uvaretin

1- [ 2,4-Dihydroxy-3- [ (2-hydroxyphenyl) methyl ] -6-methoxyphenyl ] -3-phenyl-1-propanone

C23H22O5 (378.1467162)


Uvaretin is a member of the class of dihydrochalcones that is 1,3-diphenylpropan-1-one in which the phenyl group that is bonded to the carbonyl group is substituted by hydroxy groups at positions 2 and 4, an o-hydroxybenzyl group at position 3, and a methoxy group at position 6. A cytotoxic natural product found particularly in Uvaria acuminata and Uvaria chamae. It has a role as an antineoplastic agent and a plant metabolite. It is a resorcinol, an aromatic ether, a polyketide and a member of dihydrochalcones. Uvaretin is a natural product found in Desmos chinensis, Uvaria chamae, and other organisms with data available. A member of the class of dihydrochalcones that is 1,3-diphenylpropan-1-one in which the phenyl group that is bonded to the carbonyl group is substituted by hydroxy groups at positions 2 and 4, an o-hydroxybenzyl group at position 3, and a methoxy group at position 6. A cytotoxic natural product found particularly in Uvaria acuminata and Uvaria chamae.

   

Chamuvarin

1-Propanone, 1-(4,6-dihydroxy-3-((2-hydroxyphenyl)methyl)-2-methoxyphenyl)-3-phenyl-

C23H22O5 (378.1467162)


Isouvaretin is a diarylheptanoid. Isouvaretin is a natural product found in Desmos chinensis, Uvaria chamae, and other organisms with data available.

   

Davidigenin

1- (2,4-Dihydroxyphenyl) -3- (4-hydroxyphenyl) -1-propanone

C15H14O4 (258.0892044)


A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2, and 4 respectively.

   

Glycyphyllin

1- [ 2- (alpha-L-Rhamnopyranosyloxy) -4,6-dihydroxyphenyl ] -3- (4-hydroxyphenyl) -1-propanone

C21H24O9 (420.14202539999997)


   

O-Methylodoratol

alpha-Hydroxy-4,2,4-trimethoxydihydrochalcone

C18H20O5 (316.13106700000003)


A member of the class of dihydrochalcones that is the 2-O-methyl derivative of odoratol.

   

Odoratol

2-Hydroxy-1- (2-hydroxy-4-methoxyphenyl) -3- (4-methoxyphenyl) -1-propanone

C17H18O5 (302.1154178)


A member of the class of dihydrochalcones that is dihydrochalcone substituted by a hydroxy group at position 2, methoxy groups at positions 4 and 4 and a hydroxy group at position alpha- to the ketonic group.

   

Piperaduncin B

methyl 4-hydroxy-3- [ (2S,3S) -6-hydroxy-2- (2-hydroxypropan-2-yl) -4-methoxy-7- (3-phenylpropanoyl) -2,3-dihydro-1-benzofuran-3-yl ] benzoate

C29H30O8 (506.194058)


   

3-Formyl-2,4,6-trihydroxydihydrochalcone

3-Formyl-2,4,6-trihydroxydihydrochalcone

C16H14O5 (286.0841194)


   

Momilactone A

5-ethenyl-1,5,12-trimethyl-10-oxatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadec-7-ene-11,13-dione

C20H26O3 (314.1881846)


Momilactone A is found in cereals and cereal products. Momilactone A is a constituent of Oryza sativa (rice). Momilactone A. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=51415-07-7 (retrieved 2024-09-06) (CAS RN: 51415-07-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

   

Myrigalon B

1-(2,6-Dihydroxy-4-methoxy-3,5-dimethylphenyl)-3-phenyl-1-propanone

C18H20O4 (300.13615200000004)


Myrigalon B is found in herbs and spices. Myrigalon B is isolated from Myrica gale (bog myrtle). Isolated from Myrica gale (bog myrtle). Myrigalon B is found in herbs and spices.

   

Myrigalone G

1-(2,6-dihydroxy-4-methoxy-3-methylphenyl)-3-phenylpropan-1-one

C17H18O4 (286.1205028)


Myrigalone G is found in herbs and spices. Myrigalone G is a constituent of the fruit of Myrica gale (bog myrtle). Constituent of the fruit of Myrica gale (bog myrtle). Myrigalone G is found in herbs and spices.

   

Myrigalone H

1-(2,4-Dihydroxy-6-methoxy-3-methylphenyl)-3-phenyl-1-propanone

C17H18O4 (286.1205028)


Myrigalone H is found in herbs and spices. Myrigalone H is a constituent of the fruit of Myrica gale (bog myrtle). D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics Constituent of the fruit of Myrica gale (bog myrtle). Myrigalone H is found in herbs and spices. D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents

   

1-(2,4-Dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl]-1-propanone

1-(2,4-Dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl]-1-propanone

C25H28O5 (408.1936638)


1-(2,4-Dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl]-1-propanone is found in breadfruit. 1-(2,4-Dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl]-1-propanone is a constituent of Artocarpus communis (breadfruit) Constituent of Artocarpus communis (breadfruit). 1-(2,4-Dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl]-1-propanone is found in breadfruit and fruits.

   

2-Geranyl-2',3,4,4'-tetrahydroxydihydrochalcone

1-(2,4-dihydroxyphenyl)-3-{2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,4-dihydroxyphenyl}propan-1-one

C25H30O5 (410.209313)


2-Geranyl-2,3,4,4-tetrahydroxydihydrochalcone is found in fruits. 2-Geranyl-2,3,4,4-tetrahydroxydihydrochalcone is a constituent of Artocarpus communis (breadfruit) Constituent of Artocarpus communis (breadfruit). 2-Geranyl-2,3,4,4-tetrahydroxydihydrochalcone is found in fruits.

   

Myrigalone E

1-(2-Hydroxy-4,6-dimethoxy-3-methylphenyl)-3-phenyl-1-propanone

C18H20O4 (300.13615200000004)


Myrigalone E is found in herbs and spices. Myrigalone E is a constituent of Myrica gale (bog myrtle)

   

alpha,beta-Dihydroxanthohumol

1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)propan-1-one

C21H24O5 (356.1623654)


alpha,beta-Dihydroxanthohumol is found in alcoholic beverages. alpha,beta-Dihydroxanthohumol is a constituent of hops (Humulus lupulus) Constituent of hops (Humulus lupulus). alpha,beta-Dihydroxanthohumol is found in alcoholic beverages.

   

Loureirin C

3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one

C16H16O4 (272.1048536)


Loureirin C is a member of dihydrochalcones. Loureirin C is a natural product found in Dracaena draco, Dracaena cinnabari, and other organisms with data available. Loureirin C has anti-bacterial, anti-spasmodic, anti-inflammatory, analgesic, anti-diabetic, and anti-tumor activities[1]. Loureirin C has anti-bacterial, anti-spasmodic, anti-inflammatory, analgesic, anti-diabetic, and anti-tumor activities[1].

   

Loureirin B

Propan-1-one, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-

C18H20O5 (316.13106700000003)


Loureirin B is a natural product found in Garcinia dulcis with data available. Loureirin B, a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of plasminogen activator inhibitor-1 (PAI-1), with an IC50 of 26.10?μM; Loureirin B also inhibits KATP, the phosphorylation of ERK and JNK, and has anti-diabetic activity. Loureirin B, a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of plasminogen activator inhibitor-1 (PAI-1), with an IC50 of 26.10?μM; Loureirin B also inhibits KATP, the phosphorylation of ERK and JNK, and has anti-diabetic activity. Loureirin B, a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of plasminogen activator inhibitor-1 (PAI-1), with an IC50 of 26.10?μM; Loureirin B also inhibits KATP, the phosphorylation of ERK and JNK, and has anti-diabetic activity.

   

Trilobatin

1-(2,6-dihydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)


Trilobatin is an aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties. It has a role as an anti-inflammatory agent, a sweetening agent, an antioxidant and a plant metabolite. It is an aryl beta-D-glucoside, a member of dihydrochalcones and a monosaccharide derivative. It is functionally related to a phloretin. Trilobatin is a natural product found in Malus trilobata, Balanophora tobiracola, and other organisms with data available. An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3]. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3].

   

Naringin_dihydrochalcone

1-(4-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one

C27H34O14 (582.1948464)


Naringin dihydrochalcone is a member of flavonoids and a glycoside. Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway. Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.

   

Thonningianin A

[(10R,11R,12R,13S,15R)-13-[3,5-dihydroxy-4-(3-phenylpropanoyl)phenoxy]-3,4,5,12,21,22,23-heptahydroxy-8,18-dioxo-9,14,17-trioxatetracyclo[17.4.0.02,7.010,15]tricosa-1(23),2,4,6,19,21-hexaen-11-yl] 3,4,5-trihydroxybenzoate

C42H34O21 (874.1592513999999)


Thonningianin A is a tannin. It has a role as a metabolite. thonningianin A is a natural product found in Thonningia sanguinea with data available. A natural product found in Thonningia sanguinea. Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities[1][2].

   

Ovalitenin B

3-Methoxy-1- (4-methoxybenzofuran-5-yl) -3-phenyl-1-propanone

C19H18O4 (310.1205028)


   

4-Methoxyphlorizin

2,4,6-Trihydroxy-4-methoxydihydrochalcone 2-O-glucoside

C22H26O10 (450.15258960000006)


   

Coatline A

4,2,4,alpha-Tetrahydroxy-3-C-glucopyranosyl-dihydrochalcone

C21H24O10 (436.13694039999996)


   

Phloretin 3,5-Di-C-glucoside

4,2,4,6-Tetrahydroxydihydroxychalcone 3,5-Di-C-glucoside

C27H34O15 (598.1897614000001)


   

Rubranine

(E) -3-Phenyl-1- [ (2R) -3,3abeta,4,5-tetrahydro-8-hydroxy-2,5,5-trimethyl-2alpha,4alpha-ethano-2H-pyrano [ 4,3,2-de ] -1-benzopyran-7-yl ] -2-propen-1-one

C25H26O4 (390.18309960000005)


   

4-O-Methyldavidioside

4,2-Dihydroxy-4-methoxydihydrochalcone 2-glucoside

C22H26O9 (434.15767460000006)


   

Sieboldin

3-(3,4-dihydroxyphenyl)-1-[2,6-dihydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propan-1-one

C21H24O11 (452.13185539999995)


   

confusoside

1- [ 4- (beta-D-Glucopyranosyloxy) -2-hydroxyphenyl ] -3- (4-hydroxyphenyl) -1-propanone

C21H24O9 (420.14202539999997)


   

Brosimacutin I

1- (4-Hydroxyphenyl) -3- [ 2,4-dihydroxy-3- (2,3-dihydroxy-3-methylbutyl) phenyl ] propane-1-one

C20H24O6 (360.1572804)


   

Calomelanol B

3,4-Dihydro-5,7-dihydroxy-4-phenyl-8- [ 3- (4-hydroxyphenyl) -1-oxopropyl ] -2H-1-benzopyran-2-one

C24H20O6 (404.125982)


   

Dihydroisomilletenone methyl ether

2,4,beta-Trimethoxy-3,4-methylenedioxydihydrochalcone

C19H20O6 (344.125982)


   

4-Hydroxy-2,6-dimethoxydihydrochalcone

4-Hydroxy-2,6-dimethoxydihydrochalcone

C17H18O4 (286.1205028)


   

Nubigenol

2-Hydroxy-3- (4-hydroxyphenyl) -1- (2,4,6-trihydroxyphenyl) -1-propanone

C15H14O6 (290.0790344)


   

3-Prenylrubranine

[6aS-[4(E),6a.alpha,9.beta,10a.alpha]]-1-[6a,7,8,9,10,10a-Hexahydro-3-hydroxy-6,6,9-trimethyl-2-(3-methyl-2-butenyl)-1,9-epoxy-6H-dibenzo[b,d]pyran-4-yl]-3-phenyl-2-propen-1-one

C30H34O4 (458.24569640000004)


   

Nothofagin

1-[3-[(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-2,4,6-tris(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one

C21H24O10 (436.13694039999996)


Nothofagin is a natural product found in Aspalathus linearis with data available.

   

Ceratiolin

(R) -3,5,6-Trihydroxy-4,6-dimethyl-2- (1-oxo-3-phenylpropyl) -2,4-cyclohexadien-1-one

C17H18O5 (302.1154178)


   

3,4,4,alpha-Tetrahydroxy-2-methoxydihydrochalcone

3,4,4,alpha-Tetrahydroxy-2-methoxydihydrochalcone

C16H16O6 (304.0946836)


   

4,2,4,beta-Tetrahydroxy-6-methoxydihydrochalcone

4,2,4,beta-Tetrahydroxy-6-methoxy-alpha,beta-dihydrochalcone

C16H16O6 (304.0946836)


   

Dihydromilletenone methyl ether

2,4,beta-Trimethoxy-3,4-methylenedioxydihydrochalcone

C19H20O6 (344.125982)


   

Davidioside

4,2,4-Trihydroxydihydrochalcone 2-glucoside

C21H24O9 (420.14202539999997)


   

4,4,alpha-Trihydroxy-2-methoxydihydrochalcone

4,4,alpha-Trihydroxy-2-methoxydihydrochalcone

C16H16O5 (288.0997686)


   

Phloretin 2-O-(6-O-acetylglucoside)

4,2,4,6-Tetrahydroxydihydroxychalcone 2-O- (6"-O-acetylglucoside)

C23H26O11 (478.14750460000005)


   

Licoagroside F

4,2,4,alpha-Tetrahydroxydihydrochalcone alpha-O-glucoside

C21H24O10 (436.13694039999996)


   

Helihumulone

3,5-Dihydroxy-2-methoxy-2,4-bis (3-methyl-2-butenyl) -6- (3-phenyl-1-oxopropyl) -3,5-cyclohexadien-1-one

C26H32O5 (424.2249622)


   

Ponganone VIII

3- (1,3-Benzodioxol-5-yl) -1- (5,8-dimethoxy-2,2-dimethyl-2H-1-benzopyran-6-yl) -3-methoxy-1-propanone

C24H26O7 (426.1678446)


   

Castillene E

2-Hydroxy-1- (4-hydroxybenzofuran-5-yl) -3-phenyl-1-propanone

C17H14O4 (282.0892044)


   

Calomelanol D-1

3,4-Dihydro-5,7-dihydroxy-4-phenyl-8- (3-phenyl-1-oxopropyl) -2H-1-benzopyran-2-one

C24H20O5 (388.13106700000003)


   

beta-Hydroxy-2,6-dimethoxy-3,4-methylenedioxydihydrochalcone

beta-Hydroxy-2,6-dimethoxy-3,4-methylenedioxydihydrochalcone

C18H18O6 (330.11033280000004)


   

3,4,6-Trihydroxy-2-oxo-3,5-diprenyldihydrochalcone

3,4,6-Trihydroxy-2-oxo-3,5-diprenyldihydrochalcone

C25H30O5 (410.209313)


   

4-Hydroxyglenoblone

4-Hydroxyglenoblone

C26H30O5 (422.209313)


   
   

alpha,4,2-Trihydroxy-4-O-geranyldihydrochalcone

alpha,4,2-Trihydroxy-4-O-geranyldihydrochalcone

C24H28O5 (396.1936638)


   

Zosterin

4,2-Dihydroxy-4,6-diacetoxydihydrochalcone 2-O-glucoside

C25H28O12 (520.1580688)


   

4,2,4,alpha-Tetrahydroxydihydrochalcone

4,2,4,alpha-Tetrahydroxydihydrochalcone

C15H14O5 (274.0841194)


   

2,4,alpha-Trihydroxy-4-methoxydihydrochalcone

2,4,alpha-Trihydroxy-4-methoxydihydrochalcone

C16H16O5 (288.0997686)


   

3,4,2,4,alpha-Pentahydroxydihydrochalcone

3,4,2,4,alpha-Pentahydroxydihydrochalcone

C15H14O6 (290.0790344)


   

Asebogenin

1- (2,6-Dihydroxy-4-methoxyphenyl) -3- (4-hydroxyphenyl) -1-propanone

C16H16O5 (288.0997686)


A member of the class of dihydrochalcones that is the 4-methyl ether derivative of phloretin.

   

2,2,2-Trihydroxy-5,5,5-tribenzyldiuvaretin

2"",2"",2"""-Trihydroxy-5",5"",5""-tribenzyldiuvaretin

C51H46O9 (802.3141666)


   

2,2,2-Trihydroxy-5,3,5-tribenzylisodiuvaretin

2"",2"",2"""-Trihydroxy-5",3"",5""-tribenzylisodiuvaretin

C51H46O9 (802.3141666)


   

2,6-Dihydroxy-4-methoxy-3-(2-hydroxybenzyl)dihydrochalcone

2,6-Dihydroxy-4-methoxy-3- (2-hydroxybenzyl) dihydrochalcone

C23H22O5 (378.1467162)


   

2,4-Dihydroxydihydrochalcone

2,4-DIHYDROXY-4-METHOXYDIHYDROCHALCONE

C15H14O3 (242.0942894)


   

2,4,6-Trihydroxydihydrochalcone

3-Phenyl-1- (2,4,6-trihydroxyphenyl) -1-propanone

C15H14O4 (258.0892044)


   

Dihydroflavokawin B

1-Propanone,1-(2-hydroxy-4,6-dimethoxyphenyl)- 3-phenyl-

C17H18O4 (286.1205028)


   

Dihydrocalythropsin

3,4,2-Trihydroxy-4-methoxydihydrochalcone

C16H16O5 (288.0997686)


   

4,2,4-Trihydroxy-6-methoxydihydrochalcone

4,2,4-Trihydroxy-6-methoxydihydrochalcone

C16H16O5 (288.0997686)


   

2,4-Dihydroxy-4,6-dimethoxydihydrochalcone

3-(2-hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one

C17H18O5 (302.1154178)


   

Dihydropashanone

2,6-Dihydroxy-3,4-dimethoxy-alpha,beta-dihydrochalcone

C17H18O5 (302.1154178)


   

2,6-Dihydroxy-3,4,4-trimethoxydihydrochalcone

2,6-Dihydroxy-3,4,4-trimethoxydihydrochalcone

C18H20O6 (332.125982)


   

2,4-Dihydroxy-3,4,6-trimethoxydihydrochalcone

2,4-Dihydroxy-3,4,6-trimethoxydihydrochalcone

C18H20O6 (332.125982)


   

Dihydropedicin

2,5-Dihydroxy-3,4,6-trimethoxydihydrochalcone

C18H20O6 (332.125982)


   

Dihydrokanakugiol

2-Hydroxy-3,4,5,6-tetrahydroxydihydrochalcone

C19H22O6 (346.1416312)


   

2,4-Dihydroxy-3,4-methylenedioxydihydrochalcone

2,4-Dihydroxy-3,4-methylenedioxydihydrochalcone

C16H14O5 (286.0841194)


   

2,6-Dimethoxy-3,4-methylenedioxydihydrochalcone

2,6-Dimethoxy-3,4-methylenedioxydihydrochalcone

C18H18O5 (314.1154178)


   

2,6-Dihydroxy-4,3-dimethoxy-4,5-methylenedioxydihydrochalcone

2,6-Dihydroxy-4,3-dimethoxy-4,5-methylenedioxydihydrochalcone

C18H18O7 (346.10524780000003)


   

2-Hydroxy-5,6-dimethoxy-3,4-methylenedioxyfurano[2,3:4,3] dihydrochalcon

2-Hydroxy-5,6-dimethoxy-3,4-methylenedioxyfurano [ 2",3":4,3 ] dihydrochalcone

C20H18O7 (370.1052478)


   

Chamuvaritin

1- [ 1,3-Dihydroxy-4- [ (2-hydroxyphenyl) methyl ] -9H-xanthen-2-yl ] -3-phenyl-1-propanone

C29H24O5 (452.1623654)


   

4,2,6-Trihydroxy-4-methoxy-3-methyldihydrochalcone

4,2,6-Trihydroxy-4-methoxy-3-methyldihydrochalcone

C17H18O5 (302.1154178)


   

4,2,6-Trihydroxy-4-methoxy-3,5-dimethyldihydrochalcone

4,2,6-Trihydroxy-4-methoxy-3,5-dimethyldihydrochalcone

C18H20O5 (316.13106700000003)


   

Dihydrocordoin

2-Hydroxy-4-prenyloxydihydrochalcone

C20H22O3 (310.15688620000003)


   

2,4,6-Trihydroxy-3-prenyldihydrochalcone

2,4,6-Trihydroxy-3-prenyldihydrochalcone

C20H22O4 (326.1518012)


   

2,6-Dihydroxy-4-methoxy-3-prenyldihydrochalcone

2,6-Dihydroxy-4-methoxy-3-prenyldihydrochalcone

C21H24O4 (340.1674504)


   

2-Hydroxy-6-methoxy-4-prenyloxydihydrochalcone

2-Hydroxy-6-methoxy-4-prenyloxydihydrochalcone

C21H24O4 (340.1674504)


   

2,4,6-Trihydroxy-3,5-diprenyldihydrochalcone

2,4,6-Trihydroxy-3,5-diprenyldihydrochalcone

C25H30O4 (394.214398)


   

4,2,4,6-Tetrahydroxy-3,5-diprenyldihydrochalcone

4,2,4,6-Tetrahydroxy-3,5-diprenyldihydrochalcone

C25H30O5 (410.209313)


   

2,4,6-Trihydroxy-3-methoxy-5-prenyldihydrochalcone

2,4,6-Trihydroxy-3-methoxy-5-prenyldihydrochalcone

C21H24O5 (356.1623654)


   

2,4,4-Trihydroxy-3,6,6-trimethylpyrano[2,3:6,5]dihydrochalcone

2,4,4"-Trihydroxy-3,6",6"-trimethylpyrano [ 2",3":6,5 ] dihydrochalcone

C21H24O5 (356.1623654)


   

2,4,5-Trihydroxy-3,6,6-trimetylpyrano[2,3:6,5]dihydrochalcone

2,4,5"-Trihydroxy-3,6",6"-trimethylpyrano [ 2",3":6,5 ] dihydrochalcone

C21H24O5 (356.1623654)


   

3-Geranyl-4,2,4,6-tetrahydroxy-5-prenyldihydrochalcone

3-Geranyl-4,2,4,6-tetrahydroxy-5-prenyldihydrochalcone

C30H38O5 (478.2719098)


   

3-Geranyl-3,4,2,4-tetrahydroxy-6-methoxydihydrochalcone

3-Geranyl-3,4,2,4-tetrahydroxy-6-methoxydihydrochalcone

C26H32O6 (440.2198772)


   

3-Geranyl-4,2,4,5,6-pentahydroxydihydrochalcone

3-Geranyl-4,2,4,5,6-pentahydroxydihydrochalcone

C25H30O6 (426.204228)


   

4,2,3,4,6-Pentahydroxy-5-neryldihydrochalcone

4,2,3,4,6-Pentahydroxy-5-neryldihydrochalcone

C25H30O6 (426.204228)


   

Lusianin

2,4-Dihydroxy-4,3-dimethoxydihydrochalcone

C17H18O5 (302.1154178)


   

2-Hydroxy-4-methoxydihydrochalcone

2-Hydroxy-4-methoxy-3-phenylpropiophenone

C16H16O3 (256.10993859999996)


   

2-Methoxy-4-hydroxydihydrochalcone

2-Methoxy-4-hydroxydihydrochalcone

C16H16O3 (256.10993859999996)


   

4-Hydroxy-2,4-dimethoxydihydrochalcone

4-Hydroxy-2,4-dimethoxydihydrochalcone

C17H18O4 (286.1205028)


   

2,3-Dihydroxy-4,6-dimethoxydihydrochalcone

2,3-Dihydroxy-4,6-dimethoxydihydrochalcone

C17H18O5 (302.1154178)


   

2-Hydroxy-3,4,6-trimethoxydihydrochalcone

2-Hydroxy-3,4,6-trimethoxydihydrochalcone

C18H20O5 (316.13106700000003)


   

Ponganone VII

2,4-Dimethoxy-3,4-methylenedioxydihydrochalcone

C18H18O5 (314.1154178)


   

4,4-Dihydroxy-2,6-dimethoxydihydrochalcone

3-(4-hydroxy-2,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one

C17H18O5 (302.1154178)


4,4-Dihydroxy-2,6-dimethoxydihydrochalcone is a natural product found in Soymida febrifuga and Dracaena cochinchinensis with data available.

   

2-Hydroxy-4,5,6-trimethoxydihydrochalcone

2-Hydroxy-4,5,6-trimethoxydihydrochalcone

C18H20O5 (316.13106700000003)


   

3,5-Dihydroxy-2,4,6-trimethoxydihydrochalcone

3,5-Dihydroxy-2,4,6-trimethoxydihydrochalcone

C18H20O6 (332.125982)


   

2,4,6-Trimethoxy-3,4-methylenedioxydihydrochalcone

2,4,6-Trimethoxy-3,4-methylenedioxydihydrochalcone

C19H20O6 (344.125982)


   

Crotin (chalcone)

3,4,2-Trihydroxy-6",6"-dimethylpyrano [ 2",3":4,3 ] dihydrochalcone

C20H20O5 (340.13106700000003)


   

2,4,6,3,4-Pentahydroxy-3,5-diprenyldihydrochalcone

2,4,6,3,4-Pentahydroxy- 3,5-diprenyldihydrochalcone

C25H30O6 (426.204228)


   

2,4,6,3,4-Pentahydroxy-3-geranyl-5-prenyldihydrochalcone

2,4,6,3,4-Pentahydroxy-3-geranyl-5-prenyldihydrochalcone

C30H38O6 (494.2668248)


   

2,4,6,3-Tetrahydroxy-3-geranyl-6,6-dimethylpyrano[2,3:4,5]dihydrochalcone

2,4,6,3-Tetrahydroxy-3-geranyl-6",6"-dimethylpyrano [ 2",3":4,5 ] dihydrochalcone

C30H36O6 (492.2511756)


   

4-Hydrocinnamoyl-2,2,5-trimethyl-4-cyclopentene-1,3-dione

4-Hydrocinnamoyl-2,2,5-trimethyl-4-cyclopentene-1,3-dione

C17H18O3 (270.1255878)


   

4-O-Methyldavidigenin

4,2-Dihydroxy-4-methoxydihydrochalcone

C16H16O4 (272.1048536)


   

Methyllinderatin

2,6-Dihydroxy-3- (6-isopropyl-3-methylcyclohex-2-enyl) -4-methoxydihydrochalcone

C26H32O4 (408.2300472)


   

Adunctin C

rel-(-)-1-[(1R,4S)-6-Hydroxy-4-methoxy-4-(1-methylethyl)spiro[benzofuran-2(3H),1-[2]cyclohexen]-7-yl]-3-phenyl-1-propanone

C26H30O4 (406.214398)


   

Adunctin E

(5aR) -1-Methoxy-4- (3-phenylpropionyl) -6-methyl-9alpha-isopropyl-5aalpha,6,7,8,9,9aalpha-hexahydrodibenzofuran-3,6beta-diol

C26H32O5 (424.2249622)


   

Angoletin

1- (2,4-Dihydroxy-6-methoxy-3,5-dimethylphenyl) -3-phenyl-1-propanone

C18H20O4 (300.13615200000004)


   
   

anguvetin

2,4-Dihydroxy-3- (2-hydroxybenzyl) -6-methoxy-5-methyldihydrochalcone

C24H24O5 (392.1623654)


   

Calomelanone

2,6-DIHYDROXY-4,4-DIMETHOXYDIHYDROCHALCONE

C17H18O5 (302.1154178)


   

Crotaramin

1- (5-Hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl) -3- (4-methoxyphenyl) -1-propanone

C21H22O4 (338.1518012)


   

Helilupolone

4,6-Dihydroxy-2-oxo-3,3,5-triprenyldihydrochalcone

C30H38O4 (462.2769948)


   

diuvaretin

1- [ 2,4-Dihydroxy-3,5-bis [ (2-hydroxyphenyl) methyl ] -6-methoxyphenyl ] -3-phenyl-1-propanone

C30H28O6 (484.1885788)


A member of the class of dihydrochalcones that is dihydrochalcone substituted by 2-hydroxybenzyl groups at positions 3 and 5, hydroxy groups at positions 2 and 4 and a methoxy group at position 6. Isolated from the roots of Uvaria acuminata and Uvaria chamae, it exhibits cytotoxicity towards human promyelocytic leukemia HL-60 cells.

   

Flemistrictin D

1- (5,8-Dihydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl) -3-phenylpropan-1-one

C21H22O5 (354.1467162)


   

Gancaonin J

4,2,4-Trihydroxy-3,5-diprenyloxydihydrochalcone

C25H30O4 (394.214398)


   

Grandiflorone

2,2,4,4-Tetramethyl-6- (1-oxo-3-phenylpropyl) -1,3,5-cyclohexanetrione

C19H22O4 (314.1518012)


   

isotriuvaretin

1- [ 2,4-Dihydroxy-3- [ 2-hydroxy-5- (2-hydroxybenzyl) benzyl ] -5- (2-hydroxybenzyl) -6-methoxyphenyl ] -3-phenyl-1-propanone

C37H34O7 (590.2304414)


   
   

Loureirin D

1-Propanone, 3-(2,4-dihydroxy-6-methoxyphenyl)-1-(4-hydroxyphenyl)-

C16H16O5 (288.0997686)


Loureirin D is a natural product found in Dracaena cochinchinensis with data available.

   

Neolinderatin

3-Phenyl-1-[2,4,6-trihydroxy-3,5-bis[(1R,6R)-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-yl]phenyl]-1-propanone

C35H46O4 (530.3395916)


   

Triuvaretin

1- [ 2,4-Dihydroxy-5- [ 2-hydroxy-5- (2-hydroxybenzyl) benzyl ] -3- (2-hydroxybenzyl) -6-methoxyphenyl ] -3-phenyl-1-propanone

C37H34O7 (590.2304414)


   

Uvangoletin

1-Propanone, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-

C16H16O4 (272.1048536)


   

Aspalathin

3- (3,4-Dihydroxyphenyl) -1- (3-beta-D-glucopyranosyl-2,4,6-trihydroxyphenyl) -1-propanone

C21H24O11 (452.13185539999995)


A member of the class of dihydrochalcones that is the 2-C-beta-D-glucopyranide of phloroglucinol and which is substituted at position 4 by a 3-(3,4-dihydroxyphenyl)propanoyl group. A metabolite of red bush, Aspalathus linearis (and present in the herbal tea made from the leaves), aspalathin exhibits significant hypoglycemic activity.

   

Pterosupin

beta,2,4,4-Tetrahydroxy-3- (beta-D-glucopyranosyl) -alpha,beta-dihydrochalcone

C21H24O10 (436.13694039999996)


   

Dihydrochalcone

BETA-PHENYLPROPIOPHENONE

C15H14O (210.1044594)


A member of the class of dihydrochalcones that is acetophenone in which one of the hydrogens of the methyl group is replaced by a benzyl group. CASMI2013 Challenge_4 MS2 data; [MS1] MSJ00007 CASMI2013 Challenge_4 MS1 data; [MS2] MSJ00008

   

2,6-dihydroxy-4-methoxydihydrochalcone

2,6-dihydroxy-4-methoxydihydrochalcone

C16H16O4 (272.1048536)


   

Gliricidol

3,5,2,4,beta-Pentahydroxy-4-methoxydihydrochalcone

C16H16O7 (320.0895986)


   
   

Phloretin

4,2,4,6-Tetrahydroxydihydroxychalcone

C15H14O5 (274.0841194)


relative retention time with respect to 9-anthracene Carboxylic Acid is 0.912 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.909 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.910 Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively[1].Phloretin has the potential for the treatment of rheumatoid arthritis (RA)?and allergic airway inflammation[4]. Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively[1].Phloretin has the potential for the treatment of rheumatoid arthritis (RA)?and allergic airway inflammation[4]. Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively[1].Phloretin has the potential for the treatment of rheumatoid arthritis (RA)?and allergic airway inflammation[4].

   

Rocymosin B

4,2,4,beta-Tetrahydroxydihydrochalcone 2-glucoside

C21H24O10 (436.13694039999996)