Goyazensolide (BioDeep_00000007395)

 

Secondary id: BioDeep_00000236359, BioDeep_00001870892

natural product PANOMIX_OTCML-2023


代谢物信息卡片


[(1R,3S,7R,8R,9Z)-10-(Hydroxymethyl)-1-methyl-6-methylidene-5,13-dioxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-9,11-dien-8-yl] 2-methylprop-2-enoate

化学式: C19H20O7 (360.120897)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 3.45%

分子结构信息

SMILES: C=C(C)C(=O)OC1C=C(CO)C2=CC(=O)C(C)(CC3OC(=O)C(=C)C13)O2
InChI: InChI=1S/C19H20O7/c1-9(2)17(22)24-13-5-11(8-20)12-6-15(21)19(4,26-12)7-14-16(13)10(3)18(23)25-14/h5-6,13-14,16,20H,1,3,7-8H2,2,4H3/b11-5-/t13-,14+,16+,19-/m1/s1

描述信息

同义名列表

2 个代谢物同义名

Goyazensolide; [(1R,3S,7R,8R,9Z)-10-(Hydroxymethyl)-1-methyl-6-methylidene-5,13-dioxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-9,11-dien-8-yl] 2-methylprop-2-enoate



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Marilia Elias Gallon, Angela Marie Smilanich. Effects of Host Plants on Development and Immunity of a Generalist Insect Herbivore. Journal of chemical ecology. 2023 Feb; ?(?):. doi: 10.1007/s10886-023-01410-9. [PMID: 36763248]
  • Ana Catharina Fernandes Pereira Ferreira Bernardes, Rafaela Cunha Matosinhos, Marcela Carolina de Paula Michel Araújo, Camila Helena Barros, Rodrigo Dian de Oliveira Aguiar Soares, Daniela Caldeira Costa, Daniela Sachs, Dênia Antunes Saúde-Guimarães. Sesquiterpene lactones from Lychnophora species: Antinociceptive, anti-inflammatory, and antioxidant pathways to treat acute gout. Journal of ethnopharmacology. 2021 Apr; 269(?):113738. doi: 10.1016/j.jep.2020.113738. [PMID: 33359866]
  • Clarice Izumi, Helen Julie Laure, Nayara Gonçalves Barbosa, Carolina Hassibe Thomé, Germano Aguiar Ferreira, João Paulo Barreto Sousa, Norberto Peporine Lopes, José César Rosa. Sequesterpene Lactones Isolated from a Brazilian Cerrado Plant (Eremanthus spp.) as Anti-Proliferative Compounds, Characterized by Functional and Proteomic Analysis, are Candidates for New Therapeutics in Glioblastoma. International journal of molecular sciences. 2020 07; 21(13):. doi: 10.3390/ijms21134713. [PMID: 32630308]
  • Yulin Ren, Esperanza J Carcache de Blanco, James R Fuchs, Djaja D Soejarto, Joanna E Burdette, Steven M Swanson, A Douglas Kinghorn. Potential Anticancer Agents Characterized from Selected Tropical Plants. Journal of natural products. 2019 03; 82(3):657-679. doi: 10.1021/acs.jnatprod.9b00018. [PMID: 30830783]
  • Maria De Mieri, Martin Smieško, Isidor Ismajili, Marcel Kaiser, Matthias Hamburger. Acid-Induced Rearrangement of Epoxygermacranolides: Synthesis of Furanoheliangolides and Cadinanes from Nobilin. Molecules (Basel, Switzerland). 2017 Dec; 22(12):. doi: 10.3390/molecules22122252. [PMID: 29258233]
  • Imke F Wulsten, Thais A Costa-Silva, Juliana T Mesquita, Marta L Lima, Mariana K Galuppo, Noemi N Taniwaki, Samanta E T Borborema, Fernando B Da Costa, Thomas J Schmidt, Andre G Tempone. Investigation of the Anti-Leishmania (Leishmania) infantum Activity of Some Natural Sesquiterpene Lactones. Molecules (Basel, Switzerland). 2017 Apr; 22(5):. doi: 10.3390/molecules22050685. [PMID: 28441357]
  • Bruno César de Albuquerque Ugoline, Jacqueline de Souza, Fernanda Cristina Ferrari, Zilma Schimith Ferraz-Filha, Grazielle Brandão Coelho, Dênia Antunes Saúde-Guimarães. The influence of seasonality on the content of goyazensolide and on anti-inflammatory and anti-hyperuricemic effects of the ethanolic extract of Lychnophora passerina (Brazilian arnica). Journal of ethnopharmacology. 2017 Feb; 198(?):444-450. doi: 10.1016/j.jep.2017.01.017. [PMID: 28089739]
  • Samuel A Spear, Sarah S Burns, Janet L Oblinger, Yulin Ren, Li Pan, A Douglas Kinghorn, D Bradley Welling, Long-Sheng Chang. Natural compounds as potential treatments of NF2-deficient schwannoma and meningioma: cucurbitacin D and goyazensolide. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2013 Oct; 34(8):1519-27. doi: 10.1097/mao.0b013e3182956169. [PMID: 23928514]
  • J Herrera, G Troncone, M R Sánchez, V Miguel, S E Lopez. The effect of furanoheliangolides from Tithonia diversifolia on superoxide anion generation in human neutrophils. Fitoterapia. 2007 Dec; 78(7-8):465-9. doi: 10.1016/j.fitote.2007.02.015. [PMID: 17601684]
  • Pierre Alexandre dos Santos, Maria Fernanda Castro Amarante, Ana Maria Soares Pereira, Bianca Bertoni, Suzelei Castro França, Cláudia Pessoa, Manoel Odorico de Moraes, Letícia Veras Costa-Lotufo, Marcio Roberto Pinho Pereira, Norberto Peporine Lopes. Production of an antiproliferative furanoheliangolide by Lychnophora ericoides cell culture. Chemical & pharmaceutical bulletin. 2004 Dec; 52(12):1433-5. doi: 10.1248/cpb.52.1433. [PMID: 15577239]