Dimethylallylpyrophosphate (BioDeep_00000000703)

   

natural product human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


({hydroxy[(3-methylbut-2-en-1-yl)oxy]phosphoryl}oxy)phosphonic acid

化学式: C5H12O7P2 (246.0058262)
中文名称: 二甲基丙烯基二磷酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.06%

分子结构信息

SMILES: CC(=CCOP(=O)(O)OP(=O)(O)O)C
InChI: InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h3H,4H2,1-2H3,(H,9,10)(H2,6,7,8)

描述信息

Prenyl diphosphate is a prenol phosphate that is a phosphoantigen comprising the O-pyrophosphate of prenol. It has a role as an epitope, a phosphoantigen, an Escherichia coli metabolite and a mouse metabolite. It is a conjugate acid of a prenyl diphosphate(3-).
Dimethylallylpyrophosphate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Dimethylallyl diphosphate is a natural product found in Centaurium erythraea, Streptomyces albidoflavus, and other organisms with data available.
Dimethylallylpyrophosphate is a metabolite found in or produced by Saccharomyces cerevisiae.
Dimethylallylpyrophosphate, also known as 2-isopentenyl diphosphate or delta-prenyl diphosphoric acid, belongs to the class of organic compounds known as isoprenoid phosphates. These are prenol lipids containing a phosphate group linked to an isoprene (2-methylbuta-1,3-diene) unit. Dimethylallylpyrophosphate is a very hydrophobic molecule, practically insoluble in water, and relatively neutral.
Dimethylallyl pyrophosphate (or -diphosphate) (DMAPP) is an intermediate product of both mevalonic acid (MVA) pathway and DOXP/MEP pathway. It is an isomer of isopentenyl pyrophosphate (IPP) and exists in virtually all life forms.
A prenol phosphate that is a phosphoantigen comprising the O-pyrophosphate of prenol.

同义名列表

63 个代谢物同义名

({hydroxy[(3-methylbut-2-en-1-yl)oxy]phosphoryl}oxy)phosphonic acid; 3-methylbut-2-enyl pyrophosphate (dimethylallyl-diphosphate); 2-Buten-1-ol, 3-methyl-, trihydrogen pyrophosphate (7CI,8CI); Diphosphoric acid, mono(3-methyl-2-butenyl) ester (9CI); 3-Methylbut-2-enyl phosphono hydrogen phosphoric acid; gamma,gamma-Dimethyallyl pyrophosphate ammonium salt; Diphosphoric acid, P-(3-methyl-2-buten-1-yl) ester; 2-Buten-1-ol, 3-methyl-, trihydrogen pyrophosphate; Diphosphoric acid, mono(3-methyl-2-butenyl) ester; 3-methyl-but-2-enyl phosphono hydrogen phosphate; Diphosphoric acid mono(3-methyl-2-butenyl) ester; 3-methyl-2-Buten-1-ol trihydrogen pyrophosphate; 3-methylbut-2-enyl phosphono hydrogen phosphate; 3,3-dimethylallyl pyrophosphate, (14)C-labeled; 3-methylbut-2-en-1-yl trihydrogen diphosphate; 2-Buten-1-ol, 3-methyl-, pyrophosphate (6CI); 3-Methyl-2-butenyl trihydrogen diphosphate; Gamma gamma-dimethylallyl pyrophosphate&; 1,1-Dimethyl-4-phenylpiperazinium iodide; gamma,gamma-Dimethylallyl pyrophosphate; 3,3-Dimethylallyl pyrophosphoric acid; delta2-Isopentenyl diphosphoric acid; 3-methyl-2-Buten-1-ol pyrophosphate; Dimethylallyl pyrophosphoric acid; Δ2-isopentenyl diphosphoric acid; 3-Methyl-2-butenyl pyrophosphate; Dimethylallylpyrophosphoric acid; 3-methylbut-2-enyl pyrophosphate; γ,γ-Dimethylallyl pyrophosphate; 2-Isopentenyl diphosphoric acid; Dimethylallyl diphosphoric acid; 3,3-dimethylallyl pyrophosphate; delta-Prenyl diphosphoric acid; delta2-Isopentenyl diphosphate; delta2-isopentenyl-diphosphate; Monoprenyl diphosphoric acid; Dimethylallyl pyrophosphate; dimethylallyl-pyrophosphate; Dimethylally pyrophosphate; Δ-prenyl diphosphoric acid; dimethylallylpyrophosphate; Prenol pyrophosphoric acid; Δ2-isopentenyl diphosphate; 2-Isopentenyl diphosphate; dimethylallyl-diphosphate; Dimethylallyl diphosphate; delta-Prenyl diphosphate; Prenyl diphosphoric acid; Monoprenyl diphosphate; Δ-prenyl diphosphate; Prenol pyrophosphate; prenyl-diphosphate; Prenyl diphosphate; dimethylallyl-PPi; Dimethylallyl-PP; DMADP cpd; DMAPP; DMPP; 1x07; IPE; 3-methyl-2-butenyl-1-diphosphoric acid, triammonium salt; DMAPP (ammonium salt); Dimethylallyl diphosphate



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(8)

BioCyc(2)

PlantCyc(0)

代谢反应

894 个相关的代谢反应过程信息。

Reactome(76)

BioCyc(7)

WikiPathways(5)

Plant Reactome(738)

INOH(2)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(66)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xuan Song, Chang Liu, Khalid H Dhiloo, Chao-Qun Yi, Tian-Tao Zhang, Yong-Jun Zhang. Functional characterization of a geranylgeranyl diphosphate synthase in the leaf beetle Monolepta hieroglyphica. Archives of insect biochemistry and physiology. 2024 Feb; 115(2):e22088. doi: 10.1002/arch.22088. [PMID: 38349673]
  • Guo Wei, Yudie Chen, Jianwen Wang, Liguo Feng. Molecular cloning and characterization of farnesyl diphosphate synthase from Rosa rugosa Thunb associated with salinity stress. PeerJ. 2024; 12(?):e16929. doi: 10.7717/peerj.16929. [PMID: 38435988]
  • Abira Sahu, Mohammad Golam Mostofa, Sarathi M Weraduwage, Thomas D Sharkey. Hydroxymethylbutenyl diphosphate accumulation reveals MEP pathway regulation for high CO2-induced suppression of isoprene emission. Proceedings of the National Academy of Sciences of the United States of America. 2023 10; 120(41):e2309536120. doi: 10.1073/pnas.2309536120. [PMID: 37782800]
  • Natalie Fiutek, Matthew B Couger, Stacy Pirro, Scott W Roy, José R de la Torre, Edward F Connor. Genomic Assessment of the Contribution of the Wolbachia Endosymbiont of Eurosta solidaginis to Gall Induction. International journal of molecular sciences. 2023 Jun; 24(11):. doi: 10.3390/ijms24119613. [PMID: 37298563]
  • Jiahao Liang, De Wang, Xin Li, Weiwen Huang, Chun Xie, Minghui Fu, Hongmei Zhang, Qiong Meng. In Silico Genome-Wide Mining and Analysis of Terpene Synthase Gene Family in Hevea Brasiliensis. Biochemical genetics. 2023 Jun; 61(3):1185-1209. doi: 10.1007/s10528-022-10311-7. [PMID: 36534333]
  • Toni Krause, Piera Wiesinger, Diego González-Cabanelas, Nathalie Lackus, Tobias G Köllner, Thomas Klüpfel, Jonathan Williams, Johann Rohwer, Jonathan Gershenzon, Axel Schmidt. HDR, the last enzyme in the MEP pathway, differently regulates isoprenoid biosynthesis in two woody plants. Plant physiology. 2023 Feb; ?(?):. doi: 10.1093/plphys/kiad110. [PMID: 36848194]
  • Hirosuke Oku, Ishmael Mutanda, Masashi Inafuku. Molecular characteristics of isoprene synthase and its control effects on isoprene emissions from tropical trees. Journal of plant research. 2023 Jan; 136(1):63-82. doi: 10.1007/s10265-022-01418-4. [PMID: 36367585]
  • Xueni Di, David Ortega-Alarcon, Ramu Kakumanu, Javier Iglesias-Fernandez, Lucia Diaz, Edward E K Baidoo, Adrian Velazquez-Campoy, Manuel Rodríguez-Concepción, Jordi Perez-Gil. MEP pathway products allosterically promote monomerization of deoxy-D-xylulose-5-phosphate synthase to feedback-regulate their supply. Plant communications. 2022 Dec; ?(?):100512. doi: 10.1016/j.xplc.2022.100512. [PMID: 36575800]
  • Ülo Niinemets, Bahtijor Rasulov, Eero Talts. CO2 -responsiveness of leaf isoprene emission: Why do species differ?. Plant, cell & environment. 2021 09; 44(9):3049-3063. doi: 10.1111/pce.14131. [PMID: 34155641]
  • Toni Krause, Michael Reichelt, Jonathan Gershenzon, Axel Schmidt. Analysis of the isoprenoid pathway intermediates, dimethylallyl diphosphate and isopentenyl diphosphate, from crude plant extracts by liquid chromatography tandem mass spectrometry. Phytochemical analysis : PCA. 2020 Nov; 31(6):770-777. doi: 10.1002/pca.2941. [PMID: 32337807]
  • Xin Jin, Can Baysal, Lihong Gao, Vicente Medina, Margit Drapal, Xiuzhen Ni, Yanmin Sheng, Lianxuan Shi, Teresa Capell, Paul D Fraser, Paul Christou, Changfu Zhu. The subcellular localization of two isopentenyl diphosphate isomerases in rice suggests a role for the endoplasmic reticulum in isoprenoid biosynthesis. Plant cell reports. 2020 Jan; 39(1):119-133. doi: 10.1007/s00299-019-02479-x. [PMID: 31679061]
  • Sarada D Tetali. Terpenes and isoprenoids: a wealth of compounds for global use. Planta. 2019 Jan; 249(1):1-8. doi: 10.1007/s00425-018-3056-x. [PMID: 30467631]
  • Xi Zhang, Tianyang Guo, Tong Xiang, Yiyang Dong, Jichuan Zhang, Liqun Zhang. Quantitation of isoprenoids for natural rubber biosynthesis in natural rubber latex by liquid chromatography with tandem mass spectrometry. Journal of chromatography. A. 2018 Jul; 1558(?):115-119. doi: 10.1016/j.chroma.2018.05.006. [PMID: 29773339]
  • Bahtijor Rasulov, Eero Talts, Irina Bichele, Ülo Niinemets. Evidence That Isoprene Emission Is Not Limited by Cytosolic Metabolites. Exogenous Malate Does Not Invert the Reverse Sensitivity of Isoprene Emission to High [CO2]. Plant physiology. 2018 02; 176(2):1573-1586. doi: 10.1104/pp.17.01463. [PMID: 29233849]
  • Chun-Li Liu, Jing-Yi Cai, Hao-Ran Bi, Tian-Wei Tan. A novel DMAPP-responding genetic circuit sensor for high-throughput screening and evolving isoprene synthase. Applied microbiology and biotechnology. 2018 Feb; 102(3):1381-1391. doi: 10.1007/s00253-017-8676-8. [PMID: 29243081]
  • Hiroyuki Kajiura, Nobuaki Suzuki, Yuji Tokumoto, Takuya Yoshizawa, Shinya Takeno, Kazuhito Fujiyama, Yoshinobu Kaneko, Hiroyoshi Matsumura, Yoshihisa Nakazawa. Two Eucommia farnesyl diphosphate synthases exhibit distinct enzymatic properties leading to end product preferences. Biochimie. 2017 Aug; 139(?):95-106. doi: 10.1016/j.biochi.2017.05.001. [PMID: 28478108]
  • Bok-Kyu Shin, Mihyang Kim, Jaehong Han. Exceptionally high percentage of IPP synthesis by Ginkgo biloba IspH is mainly due to Phe residue in the active site. Phytochemistry. 2017 Apr; 136(?):9-14. doi: 10.1016/j.phytochem.2017.01.012. [PMID: 28139297]
  • Julie E Chaves, Paloma Rueda Romero, Henning Kirst, Anastasios Melis. Role of isopentenyl-diphosphate isomerase in heterologous cyanobacterial (Synechocystis) isoprene production. Photosynthesis research. 2016 Dec; 130(1-3):517-527. doi: 10.1007/s11120-016-0293-3. [PMID: 27412351]
  • Bahtijor Rasulov, Eero Talts, Ülo Niinemets. Spectacular Oscillations in Plant Isoprene Emission under Transient Conditions Explain the Enigmatic CO2 Response. Plant physiology. 2016 12; 172(4):2275-2285. doi: 10.1104/pp.16.01002. [PMID: 27770061]
  • Tianhong Yang, Lingling Fang, Agnes M Rimando, Victor Sobolev, Keithanne Mockaitis, Fabricio Medina-Bolivar. A Stilbenoid-Specific Prenyltransferase Utilizes Dimethylallyl Pyrophosphate from the Plastidic Terpenoid Pathway. Plant physiology. 2016 08; 171(4):2483-98. doi: 10.1104/pp.16.00610. [PMID: 27356974]
  • Lemeng Dong, Esmer Jongedijk, Harro Bouwmeester, Alexander Van Der Krol. Monoterpene biosynthesis potential of plant subcellular compartments. The New phytologist. 2016 Jan; 209(2):679-90. doi: 10.1111/nph.13629. [PMID: 26356766]
  • Aparajita Banerjee, Alyssa L Preiser, Thomas D Sharkey. Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity. PloS one. 2016; 11(8):e0161534. doi: 10.1371/journal.pone.0161534. [PMID: 27548482]
  • Ülo Niinemets, Zhihong Sun, Eero Talts. Controls of the quantum yield and saturation light of isoprene emission in different-aged aspen leaves. Plant, cell & environment. 2015 Dec; 38(12):2707-20. doi: 10.1111/pce.12582. [PMID: 26037962]
  • Laura K Henry, Michael Gutensohn, Suzanne T Thomas, Joseph P Noel, Natalia Dudareva. Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. Proceedings of the National Academy of Sciences of the United States of America. 2015 Aug; 112(32):10050-5. doi: 10.1073/pnas.1504798112. [PMID: 26216978]
  • Bahtijor Rasulov, Irina Bichele, Katja Hüve, Vivian Vislap, Ülo Niinemets. Acclimation of isoprene emission and photosynthesis to growth temperature in hybrid aspen: resolving structural and physiological controls. Plant, cell & environment. 2015 Apr; 38(4):751-66. doi: 10.1111/pce.12435. [PMID: 25158785]
  • Cinzia Formighieri, Anastasios Melis. Carbon partitioning to the terpenoid biosynthetic pathway enables heterologous β-phellandrene production in Escherichia coli cultures. Archives of microbiology. 2014 Dec; 196(12):853-61. doi: 10.1007/s00203-014-1024-9. [PMID: 25116411]
  • Sergiy G Krasutsky, Marek Urbansky, Chad E Davis, Christian Lherbet, Robert M Coates, C Dale Poulter. Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. The Journal of organic chemistry. 2014 Oct; 79(19):9170-8. doi: 10.1021/jo501529k. [PMID: 25184438]
  • A Banerjee, T D Sharkey. Methylerythritol 4-phosphate (MEP) pathway metabolic regulation. Natural product reports. 2014 Aug; 31(8):1043-55. doi: 10.1039/c3np70124g. [PMID: 24921065]
  • Andrea Ghirardo, Louwrance Peter Wright, Zhen Bi, Maaria Rosenkranz, Pablo Pulido, Manuel Rodríguez-Concepción, Ülo Niinemets, Nicolas Brüggemann, Jonathan Gershenzon, Jörg-Peter Schnitzler. Metabolic flux analysis of plastidic isoprenoid biosynthesis in poplar leaves emitting and nonemitting isoprene. Plant physiology. 2014 May; 165(1):37-51. doi: 10.1104/pp.114.236018. [PMID: 24590857]
  • Bahtijor Rasulov, Irina Bichele, Agu Laisk, Ülo Niinemets. Competition between isoprene emission and pigment synthesis during leaf development in aspen. Plant, cell & environment. 2014 Mar; 37(3):724-41. doi: 10.1111/pce.12190. [PMID: 24033429]
  • Changfang Zhou, Ziru Li, Amy E Wiberley-Bradford, Sean E Weise, Thomas D Sharkey. Isopentenyl diphosphate and dimethylallyl diphosphate/isopentenyl diphosphate ratio measured with recombinant isopentenyl diphosphate isomerase and isoprene synthase. Analytical biochemistry. 2013 Sep; 440(2):130-6. doi: 10.1016/j.ab.2013.05.028. [PMID: 23747531]
  • Aparajita Banerjee, Yan Wu, Rahul Banerjee, Yue Li, Honggao Yan, Thomas D Sharkey. Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway. The Journal of biological chemistry. 2013 Jun; 288(23):16926-16936. doi: 10.1074/jbc.m113.464636. [PMID: 23612965]
  • Sean E Weise, Ziru Li, Allison E Sutter, Alex Corrion, Aparajita Banerjee, Thomas D Sharkey. Measuring dimethylallyl diphosphate available for isoprene synthesis. Analytical biochemistry. 2013 Apr; 435(1):27-34. doi: 10.1016/j.ab.2012.11.031. [PMID: 23262281]
  • Juan A Faraldos, Veronica Gonzalez, Amang Li, Fanglei Yu, Mustafa Köksal, David W Christianson, Rudolf K Allemann. Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. Journal of the American Chemical Society. 2012 Dec; 134(51):20844-8. doi: 10.1021/ja311022s. [PMID: 23214943]
  • Nobuaki Suzuki, Hirotaka Uefuji, Takashi Nishikawa, Yukio Mukai, Atsushi Yamashita, Masahira Hattori, Naotake Ogasawara, Takeshi Bamba, Ei-ichiro Fukusaki, Akio Kobayashi, Yoshiyuki Ogata, Nozomu Sakurai, Hideyuki Suzuki, Daisuke Shibata, Yoshihisa Nakazawa. Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver. Planta. 2012 Nov; 236(5):1405-17. doi: 10.1007/s00425-012-1679-x. [PMID: 22729820]
  • Xiao-Min Lu, Xiao-Jiao Hu, Yuan-Zeng Zhao, Wei-Bin Song, Mei Zhang, Zong-Liang Chen, Wei Chen, Yong-Bin Dong, Zhen-Hua Wang, Jin-Sheng Lai. Map-based cloning of zb7 encoding an IPP and DMAPP synthase in the MEP pathway of maize. Molecular plant. 2012 Sep; 5(5):1100-12. doi: 10.1093/mp/sss038. [PMID: 22498772]
  • Eliana Gonzales-Vigil, David E Hufnagel, Jeongwoon Kim, Robert L Last, Cornelius S Barry. Evolution of TPS20-related terpene synthases influences chemical diversity in the glandular trichomes of the wild tomato relative Solanum habrochaites. The Plant journal : for cell and molecular biology. 2012 Sep; 71(6):921-35. doi: 10.1111/j.1365-313x.2012.05040.x. [PMID: 22563774]
  • Shuiqin Wu, Zuodong Jiang, Chase Kempinski, S Eric Nybo, Satrio Husodo, Robert Williams, Joe Chappell. Engineering triterpene metabolism in tobacco. Planta. 2012 Sep; 236(3):867-77. doi: 10.1007/s00425-012-1680-4. [PMID: 22729821]
  • Maryam Darabi, Ali Izadi-Darbandi, Ali Masoudi-Nejad, Mohammad Reza Naghavi, Ghorbanali Nemat-Zadeh. Bioinformatics study of the 3-hydroxy-3-methylglotaryl-coenzyme A reductase (HMGR) gene in Gramineae. Molecular biology reports. 2012 Sep; 39(9):8925-35. doi: 10.1007/s11033-012-1761-2. [PMID: 22722993]
  • Michael Behr, Václav Motyka, Fabian Weihmann, Jiří Malbeck, Holger B Deising, Stefan G R Wirsel. Remodeling of cytokinin metabolism at infection sites of Colletotrichum graminicola on maize leaves. Molecular plant-microbe interactions : MPMI. 2012 Aug; 25(8):1073-82. doi: 10.1094/mpmi-01-12-0012-r. [PMID: 22746825]
  • Zhong-Bao Yang, Dejene Eticha, Alfonso Albacete, Idupulapati Madhusudana Rao, Thomas Roitsch, Walter Johannes Horst. Physiological and molecular analysis of the interaction between aluminium toxicity and drought stress in common bean (Phaseolus vulgaris). Journal of experimental botany. 2012 May; 63(8):3109-25. doi: 10.1093/jxb/ers038. [PMID: 22371077]
  • Danilo Aros, Veronica Gonzalez, Rudolf K Allemann, Carsten T Müller, Carlo Rosati, Hilary J Rogers. Volatile emissions of scented Alstroemeria genotypes are dominated by terpenes, and a myrcene synthase gene is highly expressed in scented Alstroemeria flowers. Journal of experimental botany. 2012 Apr; 63(7):2739-52. doi: 10.1093/jxb/err456. [PMID: 22268153]
  • Yimian Ma, Lichai Yuan, Bin Wu, Xian'en Li, Shilin Chen, Shanfa Lu. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. Journal of experimental botany. 2012 Apr; 63(7):2809-23. doi: 10.1093/jxb/err466. [PMID: 22291132]
  • Motoyoshi Noike, Chengwei Liu, Yusuke Ono, Yoshimitsu Hamano, Tomonobu Toyomasu, Takeshi Sassa, Nobuo Kato, Tohru Dairi. An enzyme catalyzing O-prenylation of the glucose moiety of fusicoccin A, a diterpene glucoside produced by the fungus Phomopsis amygdali. Chembiochem : a European journal of chemical biology. 2012 Mar; 13(4):566-73. doi: 10.1002/cbic.201100725. [PMID: 22287087]
  • Insaf Thabet, Grégory Guirimand, Anthony Guihur, Arnaud Lanoue, Vincent Courdavault, Nicolas Papon, Sadok Bouzid, Nathalie Giglioli-Guivarc'h, Andrew J Simkin, Marc Clastre. Characterization and subcellular localization of geranylgeranyl diphosphate synthase from Catharanthus roseus. Molecular biology reports. 2012 Mar; 39(3):3235-43. doi: 10.1007/s11033-011-1091-9. [PMID: 21706164]
  • Zhihong Sun, Lucian Copolovici, Ülo Niinemets. Can the capacity for isoprene emission acclimate to environmental modifications during autumn senescence in temperate deciduous tree species Populus tremula?. Journal of plant research. 2012 Mar; 125(2):263-74. doi: 10.1007/s10265-011-0429-7. [PMID: 21584787]
  • Sol A Green, Xiuyin Chen, Niels J Nieuwenhuizen, Adam J Matich, Mindy Y Wang, Barry J Bunn, Yar-Khing Yauk, Ross G Atkinson. Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). Journal of experimental botany. 2012 Mar; 63(5):1951-67. doi: 10.1093/jxb/err393. [PMID: 22162874]
  • Raimund Nagel, Jonathan Gershenzon, Axel Schmidt. Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry. Analytical biochemistry. 2012 Mar; 422(1):33-8. doi: 10.1016/j.ab.2011.12.037. [PMID: 22266300]
  • Djédoux Maxime Angaman, Rocco Petrizzo, Francesc Hernández-Gras, Carmen Romero-Segura, Irene Pateraki, Montserrat Busquets, Albert Boronat. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. Plant methods. 2012 Jan; 8(1):1. doi: 10.1186/1746-4811-8-1. [PMID: 22243738]
  • Adelene Ai Lian Song, Janna O Abdullah, Mohd Puad Abdullah, Norazizah Shafee, Raha A Rahim. Functional expression of an orchid fragrance gene in Lactococcus lactis. International journal of molecular sciences. 2012; 13(2):1582-1597. doi: 10.3390/ijms13021582. [PMID: 22408409]
  • Amy M Trowbridge, Dolores Asensio, Allyson S D Eller, Danielle A Way, Michael J Wilkinson, Jörg-Peter Schnitzler, Robert B Jackson, Russell K Monson. Contribution of various carbon sources toward isoprene biosynthesis in poplar leaves mediated by altered atmospheric CO2 concentrations. PloS one. 2012; 7(2):e32387. doi: 10.1371/journal.pone.0032387. [PMID: 22384238]
  • Md Sarfaraj Hussain, Sheeba Fareed, Saba Ansari, Md Akhlaquer Rahman, Iffat Zareen Ahmad, Mohd Saeed. Current approaches toward production of secondary plant metabolites. Journal of pharmacy & bioallied sciences. 2012 Jan; 4(1):10-20. doi: 10.4103/0975-7406.92725. [PMID: 22368394]
  • Xiumin Fu, Wenbin Kong, Gang Peng, Jingyi Zhou, Muhammad Azam, Changjie Xu, Don Grierson, Kunsong Chen. Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. Journal of experimental botany. 2012 Jan; 63(1):341-54. doi: 10.1093/jxb/err284. [PMID: 21994170]
  • Tahira Fatima, Crystal L Snyder, William R Schroeder, Dustin Cram, Raju Datla, David Wishart, Randall J Weselake, Priti Krishna. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. PloS one. 2012; 7(4):e34099. doi: 10.1371/journal.pone.0034099. [PMID: 22558083]
  • Hongmei Luo, Chao Sun, Yongzhen Sun, Qiong Wu, Ying Li, Jingyuan Song, Yunyun Niu, Xianglin Cheng, Hongxi Xu, Chuyuan Li, Juyan Liu, André Steinmetz, Shilin Chen. Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. BMC genomics. 2011 Dec; 12 Suppl 5(?):S5. doi: 10.1186/1471-2164-12-s5-s5. [PMID: 22369100]
  • Roberto A Barrero, Brett Chapman, Yanfang Yang, Paula Moolhuijzen, Gabriel Keeble-Gagnère, Nan Zhang, Qi Tang, Matthew I Bellgard, Deyou Qiu. De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes. BMC genomics. 2011 Dec; 12(?):600. doi: 10.1186/1471-2164-12-600. [PMID: 22151917]
  • Marc Clastre, Nicolas Papon, Vincent Courdavault, Nathalie Giglioli-Guivarc'h, Benoit St-Pierre, Andrew J Simkin. Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. Plant signaling & behavior. 2011 Dec; 6(12):2044-6. doi: 10.4161/psb.6.12.18173. [PMID: 22080790]
  • Axel Schmidt, Raimund Nagel, Trygve Krekling, Erik Christiansen, Jonathan Gershenzon, Paal Krokene. Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). Plant molecular biology. 2011 Dec; 77(6):577-90. doi: 10.1007/s11103-011-9832-7. [PMID: 22002747]
  • Insaf Thabet, Grégory Guirimand, Vincent Courdavault, Nicolas Papon, Stéphanie Godet, Christelle Dutilleul, Sadok Bouzid, Nathalie Giglioli-Guivarc'h, Marc Clastre, Andrew J Simkin. The subcellular localization of periwinkle farnesyl diphosphate synthase provides insight into the role of peroxisome in isoprenoid biosynthesis. Journal of plant physiology. 2011 Nov; 168(17):2110-6. doi: 10.1016/j.jplph.2011.06.017. [PMID: 21872968]
  • Chun Sui, Jie Zhang, Jianhe Wei, Shilin Chen, Ying Li, Jiesen Xu, Yue Jin, Caixiang Xie, Zhihui Gao, Hongjiang Chen, Chengmin Yang, Zheng Zhang, Yanhong Xu. Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins. BMC genomics. 2011 Nov; 12(?):539. doi: 10.1186/1471-2164-12-539. [PMID: 22047182]
  • Petra M Bleeker, Eleni A Spyropoulou, Paul J Diergaarde, Hanne Volpin, Michiel T J De Both, Philipp Zerbe, Joerg Bohlmann, Vasiliki Falara, Yuki Matsuba, Eran Pichersky, Michel A Haring, Robert C Schuurink. RNA-seq discovery, functional characterization, and comparison of sesquiterpene synthases from Solanum lycopersicum and Solanum habrochaites trichomes. Plant molecular biology. 2011 Nov; 77(4-5):323-36. doi: 10.1007/s11103-011-9813-x. [PMID: 21818683]
  • Juri Battilana, Francesco Emanuelli, Giorgio Gambino, Ivana Gribaudo, Flavia Gasperi, Paul K Boss, Maria Stella Grando. Functional effect of grapevine 1-deoxy-D-xylulose 5-phosphate synthase substitution K284N on Muscat flavour formation. Journal of experimental botany. 2011 Nov; 62(15):5497-508. doi: 10.1093/jxb/err231. [PMID: 21868399]
  • Yunliu Zeng, Zhiyong Pan, Yuduan Ding, Andan Zhu, Hongbo Cao, Qiang Xu, Xiuxin Deng. A proteomic analysis of the chromoplasts isolated from sweet orange fruits [Citrus sinensis (L.) Osbeck]. Journal of experimental botany. 2011 Nov; 62(15):5297-309. doi: 10.1093/jxb/err140. [PMID: 21841170]
  • Yongzhen Sun, Hongmei Luo, Ying Li, Chao Sun, Jingyuan Song, Yunyun Niu, Yingjie Zhu, Liang Dong, Aiping Lv, Enzo Tramontano, Shilin Chen. Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport. BMC genomics. 2011 Oct; 12(?):533. doi: 10.1186/1471-2164-12-533. [PMID: 22035094]
  • Qi Tang, Xiaojun Ma, Changming Mo, Iain W Wilson, Cai Song, Huan Zhao, Yanfang Yang, Wei Fu, Deyou Qiu. An efficient approach to finding Siraitia grosvenorii triterpene biosynthetic genes by RNA-seq and digital gene expression analysis. BMC genomics. 2011 Jul; 12(?):343. doi: 10.1186/1471-2164-12-343. [PMID: 21729270]
  • Wei Wen, Rongmin Yu. Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective. Pharmacognosy reviews. 2011 Jul; 5(10):189-94. doi: 10.4103/0973-7847.91118. [PMID: 22279377]
  • Ying-Hua Su, Yu-Bo Liu, Xian-Sheng Zhang. Auxin-cytokinin interaction regulates meristem development. Molecular plant. 2011 Jul; 4(4):616-25. doi: 10.1093/mp/ssr007. [PMID: 21357646]
  • Dennis W Gray, Steven R Breneman, Lauren A Topper, Thomas D Sharkey. Biochemical characterization and homology modeling of methylbutenol synthase and implications for understanding hemiterpene synthase evolution in plants. The Journal of biological chemistry. 2011 Jun; 286(23):20582-90. doi: 10.1074/jbc.m111.237438. [PMID: 21504898]
  • Yu-Juan Zhong, Jun-Chao Huang, Jin Liu, Yin Li, Yue Jiang, Zeng-Fu Xu, Gerhard Sandmann, Feng Chen. Functional characterization of various algal carotenoid ketolases reveals that ketolating zeaxanthin efficiently is essential for high production of astaxanthin in transgenic Arabidopsis. Journal of experimental botany. 2011 Jun; 62(10):3659-69. doi: 10.1093/jxb/err070. [PMID: 21398427]
  • Stuart Meier, Oren Tzfadia, Ratnakar Vallabhaneni, Chris Gehring, Eleanore T Wurtzel. A transcriptional analysis of carotenoid, chlorophyll and plastidial isoprenoid biosynthesis genes during development and osmotic stress responses in Arabidopsis thaliana. BMC systems biology. 2011 May; 5(?):77. doi: 10.1186/1752-0509-5-77. [PMID: 21595952]
  • Qiuju Yu, Sandro Ghisla, Joseph Hirschberg, Varda Mann, Peter Beyer. Plant carotene cis-trans isomerase CRTISO: a new member of the FAD(RED)-dependent flavoproteins catalyzing non-redox reactions. The Journal of biological chemistry. 2011 Mar; 286(10):8666-8676. doi: 10.1074/jbc.m110.208017. [PMID: 21209101]
  • Simon Atsbaha Zebelo, Cinzia M Bertea, Simone Bossi, Andrea Occhipinti, Giorgio Gnavi, Massimo E Maffei. Chrysolina herbacea modulates terpenoid biosynthesis of Mentha aquatica L. PloS one. 2011 Mar; 6(3):e17195. doi: 10.1371/journal.pone.0017195. [PMID: 21408066]
  • Elizabeth Cordoba, Helena Porta, Analilia Arroyo, Carolina San Román, Luis Medina, Manuel Rodríguez-Concepción, Patricia León. Functional characterization of the three genes encoding 1-deoxy-D-xylulose 5-phosphate synthase in maize. Journal of experimental botany. 2011 Mar; 62(6):2023-38. doi: 10.1093/jxb/erq393. [PMID: 21199890]
  • Andrea Ghirardo, Jessica Gutknecht, Ina Zimmer, Nicolas Brüggemann, Jörg-Peter Schnitzler. Biogenic volatile organic compound and respiratory CO2 emissions after 13C-labeling: online tracing of C translocation dynamics in poplar plants. PloS one. 2011 Feb; 6(2):e17393. doi: 10.1371/journal.pone.0017393. [PMID: 21387007]
  • Ziru Li, Ellen A Ratliff, Thomas D Sharkey. Effect of temperature on postillumination isoprene emission in oak and poplar. Plant physiology. 2011 Feb; 155(2):1037-46. doi: 10.1104/pp.110.167551. [PMID: 21177471]
  • Codruta Ignea, Ivana Cvetkovic, Sofia Loupassaki, Panagiotis Kefalas, Christopher B Johnson, Sotirios C Kampranis, Antonios M Makris. Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. Microbial cell factories. 2011 Jan; 10(?):4. doi: 10.1186/1475-2859-10-4. [PMID: 21276210]
  • Kazunori Okada. The biosynthesis of isoprenoids and the mechanisms regulating it in plants. Bioscience, biotechnology, and biochemistry. 2011; 75(7):1219-25. doi: 10.1271/bbb.110228. [PMID: 21737944]
  • Federico Brilli, Taina M Ruuskanen, Ralf Schnitzhofer, Markus Müller, Martin Breitenlechner, Vinzenz Bittner, Georg Wohlfahrt, Francesco Loreto, Armin Hansel. Detection of plant volatiles after leaf wounding and darkening by proton transfer reaction 'time-of-flight' mass spectrometry (PTR-TOF). PloS one. 2011; 6(5):e20419. doi: 10.1371/journal.pone.0020419. [PMID: 21637822]
  • Da Cheng Hao, GuangBo Ge, PeiGen Xiao, YanYan Zhang, Ling Yang. The first insight into the tissue specific taxus transcriptome via Illumina second generation sequencing. PloS one. 2011; 6(6):e21220. doi: 10.1371/journal.pone.0021220. [PMID: 21731678]
  • William N Hunter. Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites. Current topics in medicinal chemistry. 2011; 11(16):2048-59. doi: 10.2174/156802611796575867. [PMID: 21619509]
  • Manuel Rodríguez-Concepción. Supply of precursors for carotenoid biosynthesis in plants. Archives of biochemistry and biophysics. 2010 Dec; 504(1):118-22. doi: 10.1016/j.abb.2010.06.016. [PMID: 20561506]
  • Francesco Emanuelli, Juri Battilana, Laura Costantini, Loïc Le Cunff, Jean-Michel Boursiquot, Patrice This, Maria S Grando. A candidate gene association study on muscat flavor in grapevine (Vitis vinifera L.). BMC plant biology. 2010 Nov; 10(?):241. doi: 10.1186/1471-2229-10-241. [PMID: 21062440]
  • Diane M Martin, Sébastien Aubourg, Marina B Schouwey, Laurent Daviet, Michel Schalk, Omid Toub, Steven T Lund, Jörg Bohlmann. Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays. BMC plant biology. 2010 Oct; 10(?):226. doi: 10.1186/1471-2229-10-226. [PMID: 20964856]
  • Hsing-Mao Chu, Feng-Yuan Chen, Tzu-Ping Ko, Andrew H-J Wang. Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates. FEBS letters. 2010 Sep; 584(18):4083-8. doi: 10.1016/j.febslet.2010.08.038. [PMID: 20807533]
  • Usha Kiran, Mauji Ram, Mather Ali Khan, Salim Khan, Prabhakar Jha, Afshar Alam, Malik Zainul Abdin. Structural and functional characterization of HMG-COA reductase from Artemisia annua. Bioinformation. 2010 Sep; 5(4):146-9. doi: 10.6026/97320630005146. [PMID: 21364776]
  • Mustafa Köksal, Ina Zimmer, Jörg-Peter Schnitzler, David W Christianson. Structure of isoprene synthase illuminates the chemical mechanism of teragram atmospheric carbon emission. Journal of molecular biology. 2010 Sep; 402(2):363-73. doi: 10.1016/j.jmb.2010.07.009. [PMID: 20624401]
  • Katja Behnke, Andreas Kaiser, Ina Zimmer, Nicolas Brüggemann, Dennis Janz, Andrea Polle, Rüdiger Hampp, Robert Hänsch, Jennifer Popko, Philippe Schmitt-Kopplin, Barbara Ehlting, Heinz Rennenberg, Csengele Barta, Francesco Loreto, Jörg-Peter Schnitzler. RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis. Plant molecular biology. 2010 Sep; 74(1-2):61-75. doi: 10.1007/s11103-010-9654-z. [PMID: 20526857]
  • Laurence G Cool, Karl E Vermillion, Gary R Takeoka, Rosalind Y Wong. Irregular sesquiterpenoids from Ligusticum grayi roots. Phytochemistry. 2010 Sep; 71(13):1545-57. doi: 10.1016/j.phytochem.2010.06.003. [PMID: 20615518]
  • Gavin M George, Margaretha J van der Merwe, Adriano Nunes-Nesi, Rolene Bauer, Alisdair R Fernie, Jens Kossmann, James R Lloyd. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. Plant physiology. 2010 Sep; 154(1):55-66. doi: 10.1104/pp.110.157776. [PMID: 20605913]
  • Gustavo G L Costa, Kiara C Cardoso, Luís E V Del Bem, Aline C Lima, Muciana A S Cunha, Luciana de Campos-Leite, Renato Vicentini, Fábio Papes, Raquel C Moreira, José A Yunes, Francisco A P Campos, Márcio J Da Silva. Transcriptome analysis of the oil-rich seed of the bioenergy crop Jatropha curcas L. BMC genomics. 2010 Aug; 11(?):462. doi: 10.1186/1471-2164-11-462. [PMID: 20691070]
  • Mitsuko Kishi-Kaboshi, Kazunori Okada, Leona Kurimoto, Shinya Murakami, Toshiaki Umezawa, Naoto Shibuya, Hisakazu Yamane, Akio Miyao, Hiroshi Takatsuji, Akira Takahashi, Hirohiko Hirochika. A rice fungal MAMP-responsive MAPK cascade regulates metabolic flow to antimicrobial metabolite synthesis. The Plant journal : for cell and molecular biology. 2010 Aug; 63(4):599-612. doi: 10.1111/j.1365-313x.2010.04264.x. [PMID: 20525005]
  • Anthony L Schilmiller, Dennis P Miner, Matthew Larson, Eric McDowell, David R Gang, Curtis Wilkerson, Robert L Last. Studies of a biochemical factory: tomato trichome deep expressed sequence tag sequencing and proteomics. Plant physiology. 2010 Jul; 153(3):1212-23. doi: 10.1104/pp.110.157214. [PMID: 20431087]
  • Claudia E Vickers, Malcolm Possell, C Nicholas Hewitt, Philip M Mullineaux. Genetic structure and regulation of isoprene synthase in Poplar (Populus spp.). Plant molecular biology. 2010 Jul; 73(4-5):547-58. doi: 10.1007/s11103-010-9642-3. [PMID: 20467886]
  • Michelle Andrews, David H Huizinga, Dring N Crowell. The CaaX specificities of Arabidopsis protein prenyltransferases explain era1 and ggb phenotypes. BMC plant biology. 2010 Jun; 10(?):118. doi: 10.1186/1471-2229-10-118. [PMID: 20565889]
  • Kazuaki Ohara, Kanako Sasaki, Kazufumi Yazaki. Two solanesyl diphosphate synthases with different subcellular localizations and their respective physiological roles in Oryza sativa. Journal of experimental botany. 2010 Jun; 61(10):2683-92. doi: 10.1093/jxb/erq103. [PMID: 20421194]
  • Mohamed A Ibrahim, Maarit Mäenpää, Viivi Hassinen, Sari Kontunen-Soppela, Lukás Malec, Matti Rousi, Liisa Pietikäinen, Arja Tervahauta, Sirpa Kärenlampi, Jarmo K Holopainen, Elina J Oksanen. Elevation of night-time temperature increases terpenoid emissions from Betula pendula and Populus tremula. Journal of experimental botany. 2010 Jun; 61(6):1583-95. doi: 10.1093/jxb/erq034. [PMID: 20181662]
  • Ying Li, Hong-Mei Luo, Chao Sun, Jing-Yuan Song, Yong-Zhen Sun, Qiong Wu, Ning Wang, Hui Yao, André Steinmetz, Shi-Lin Chen. EST analysis reveals putative genes involved in glycyrrhizin biosynthesis. BMC genomics. 2010 Apr; 11(?):268. doi: 10.1186/1471-2164-11-268. [PMID: 20423525]
  • Liting Lim, Geoffrey Ian McFadden. The evolution, metabolism and functions of the apicoplast. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2010 Mar; 365(1541):749-63. doi: 10.1098/rstb.2009.0273. [PMID: 20124342]
  • Lide Arana, Patricia Gangoiti, Alberto Ouro, Miguel Trueba, Antonio Gómez-Muñoz. Ceramide and ceramide 1-phosphate in health and disease. Lipids in health and disease. 2010 Feb; 9(?):15. doi: 10.1186/1476-511x-9-15. [PMID: 20137073]