Aurothioglucose (BioDeep_00000006682)
代谢物信息卡片
Aurothioglucose
化学式: C6H11AuO5S (391.9993)
中文名称: 硫代葡萄糖
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C1C(C(C(C(O1)[S-])O)O)O)O.[Au+]
InChI: /q
描述信息
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01C - Specific antirheumatic agents > M01CB - Gold preparations
D018501 - Antirheumatic Agents
同义名列表
2 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:2930
- KEGG: C08193
- KEGGdrug: D00991
- PubChem: 6104
- Metlin: METLIN66845
- DrugBank: DB09121
- MeSH: Aurothioglucose
- CAS: 12192-57-3
- PubChem: 10392
- NIKKAJI: J34.142H
- KNApSAcK: 2930
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Cuihong Wang, Yuhua Jiang, Xiaohong Li, Likuan Hu. Thioglucose-bound gold nanoparticles increase the radiosensitivity of a triple-negative breast cancer cell line (MDA-MB-231).
Breast cancer (Tokyo, Japan).
2015 Jul; 22(4):413-20. doi:
10.1007/s12282-013-0496-9. [PMID: 24114595] - Bálint Botz, Kata Bölcskei, László Kereskai, Miklós Kovács, Tamás Németh, Krisztián Szigeti, Ildikó Horváth, Domokos Máthé, Noémi Kovács, Hitoshi Hashimoto, Dóra Reglődi, János Szolcsányi, Erika Pintér, Attila Mócsai, Zsuzsanna Helyes. Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model.
Arthritis & rheumatology (Hoboken, N.J.).
2014 Oct; 66(10):2739-50. doi:
10.1002/art.38772. [PMID: 25048575] - Min Wan, Karla F Leavens, Danish Saleh, Rachael M Easton, David A Guertin, Timothy R Peterson, Klaus H Kaestner, David M Sabatini, Morris J Birnbaum. Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.
Cell metabolism.
2011 Oct; 14(4):516-27. doi:
10.1016/j.cmet.2011.09.001. [PMID: 21982711] - Mitsunari Ogasawara, Akira Hirose, Masafumi Ono, Kosuke Aritake, Yasuko Nozaki, Masaya Takahashi, Nobuto Okamoto, Shuji Sakamoto, Shinji Iwasaki, Taketoshi Asanuma, Taketoshi Taniguchi, Yoshihiro Urade, Saburo Onishi, Toshiji Saibara, Jude A Oben. A novel and comprehensive mouse model of human non-alcoholic steatohepatitis with the full range of dysmetabolic and histological abnormalities induced by gold thioglucose and a high-fat diet.
Liver international : official journal of the International Association for the Study of the Liver.
2011 Apr; 31(4):542-51. doi:
10.1111/j.1478-3231.2010.02443.x. [PMID: 21382165] - Hiroshi Karasawa, Kiyosumi Takaishi, Yoshihiro Kumagae. Obesity-induced diabetes in mouse strains treated with gold thioglucose: a novel animal model for studying β-cell dysfunction.
Obesity (Silver Spring, Md.).
2011 Mar; 19(3):514-21. doi:
10.1038/oby.2010.171. [PMID: 20706204] - Adam P Lothrop, Erik L Ruggles, Robert J Hondal. No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue.
Biochemistry.
2009 Jul; 48(26):6213-23. doi:
10.1021/bi802146w. [PMID: 19366212] - Ramesh K Goyal, Sanjay V Kadnur. Beneficial effects of Zingiber officinale on goldthioglucose induced obesity.
Fitoterapia.
2006 Apr; 77(3):160-3. doi:
10.1016/j.fitote.2006.01.005. [PMID: 16513292] - Mathias Röhl, Manolis Pasparakis, Stephanie Baudler, Julia Baumgartl, Dinesh Gautam, Marion Huth, Rossana De Lorenzi, Wilhelm Krone, Klaus Rajewsky, Jens C Brüning. Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.
The Journal of clinical investigation.
2004 Feb; 113(3):474-81. doi:
10.1172/jci18712. [PMID: 14755344] - L G Lyngdorf, S Gregersen, A Daugherty, E Falk. Paradoxical reduction of atherosclerosis in apoE-deficient mice with obesity-related type 2 diabetes.
Cardiovascular research.
2003 Oct; 59(4):854-62. doi:
10.1016/s0008-6363(03)00506-6. [PMID: 14553825] - Xiao-Ming Du, Ning-Yi Sun, Jun Hayashi, Yang Chen, Minoru Sugiura, Yukihiro Shoyama. Hepatoprotective and antihyperliposis activities of in vitro cultured Anoectochilus formosanus.
Phytotherapy research : PTR.
2003 Jan; 17(1):30-3. doi:
10.1002/ptr.1057. [PMID: 12557243] - Michelle H Lewin, John R Arthur, Rudolph A Riemersma, Fergus Nicol, Simon W Walker, E Margaret Millar, Alexander F Howie, Geoffrey J Beckett. Selenium supplementation acting through the induction of thioredoxin reductase and glutathione peroxidase protects the human endothelial cell line EAhy926 from damage by lipid hydroperoxides.
Biochimica et biophysica acta.
2002 Dec; 1593(1):85-92. doi:
10.1016/s0167-4889(02)00333-6. [PMID: 12431787] - Matthias Blüher, M Dodson Michael, Odile D Peroni, Kohjiro Ueki, Nathan Carter, Barbara B Kahn, C Ronald Kahn. Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance.
Developmental cell.
2002 Jul; 3(1):25-38. doi:
10.1016/s1534-5807(02)00199-5. [PMID: 12110165] - Britta Siegmund, Kelly C Lear-Kaul, Raffaella Faggioni, Giamila Fantuzzi. Leptin deficiency, not obesity, protects mice from Con A-induced hepatitis.
European journal of immunology.
2002 02; 32(2):552-60. doi:
10.1002/1521-4141(200202)32:2<552::aid-immu552>3.0.co;2-h. [PMID: 11828372] - E Naruta, V Buko. Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2001 Oct; 53(5):393-8. doi:
10.1078/0940-2993-00205. [PMID: 11817109] - C L VanPutte, D S MacKenzie, J G Eales. Characterization of hepatic low-K(m) outer-ring deiodination in red drum (Sciaenops ocellatus).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
2001 Mar; 128(3):413-23. doi:
10.1016/s1096-4959(00)00348-1. [PMID: 11250536] - J Pourahmad, S Ross, P J O'Brien. Lysosomal involvement in hepatocyte cytotoxicity induced by Cu(2+) but not Cd(2+).
Free radical biology & medicine.
2001 Jan; 30(1):89-97. doi:
10.1016/s0891-5849(00)00450-0. [PMID: 11134899] - J M Bryson, J L Phuyal, V Swan, I D Caterson. Leptin has acute effects on glucose and lipid metabolism in both lean and gold thioglucose-obese mice.
The American journal of physiology.
1999 09; 277(3):E417-22. doi:
10.1152/ajpendo.1999.277.3.e417. [PMID: 10484352] - J M Bryson, V R Wensley, J L Phuyal, I D Caterson, G J Cooney. Chronic administration of BRL 26830A for 9 weeks improves insulin sensitivity but does not prevent weight gain in gold-thioglucose obese mice.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
1999 May; 31(5):317-22. doi:
10.1055/s-2007-978744. [PMID: 10422727] - J M Bryson, J L Phuyal, D R Proctor, S C Blair, I D Caterson, G J Cooney. Plasma insulin rise precedes rise in ob mRNA expression and plasma leptin in gold thioglucose-obese mice.
The American journal of physiology.
1999 02; 276(2):E358-64. doi:
10.1152/ajpendo.1999.276.2.e358. [PMID: 9950797] - A D Smith, C A Guidry, V C Morris, O A Levander. Aurothioglucose inhibits murine thioredoxin reductase activity in vivo.
The Journal of nutrition.
1999 Jan; 129(1):194-8. doi:
10.1093/jn/129.1.194. [PMID: 9915899] - D Kostová, E Michnová. The effect of goldthioglucose on peroxidative processes in mice.
Physiological research.
1999; 48(1):79-81. doi:
. [PMID: 10470870] - G Hollopeter, J C Erickson, R D Palmiter. Role of neuropeptide Y in diet-, chemical- and genetic-induced obesity of mice.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
1998 Jun; 22(6):506-12. doi:
10.1038/sj.ijo.0800615. [PMID: 9665670] - F Shabani, J McNeil, L Tippett. The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCI) is suppressed by anti-rheumatic drugs.
Free radical research.
1998 Feb; 28(2):115-23. doi:
10.3109/10715769809065797. [PMID: 9645388] - J Ventre, T Doebber, M Wu, K MacNaul, K Stevens, M Pasparakis, G Kollias, D E Moller. Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice.
Diabetes.
1997 Sep; 46(9):1526-31. doi:
10.2337/diab.46.9.1526. [PMID: 9287059] - K E Hill, G W McCollum, M E Boeglin, R F Burk. Thioredoxin reductase activity is decreased by selenium deficiency.
Biochemical and biophysical research communications.
1997 May; 234(2):293-5. doi:
10.1006/bbrc.1997.6618. [PMID: 9177261] - K L Houseknecht, C S Mantzoros, R Kuliawat, E Hadro, J S Flier, B B Kahn. Evidence for leptin binding to proteins in serum of rodents and humans: modulation with obesity.
Diabetes.
1996 Nov; 45(11):1638-43. doi:
10.2337/diab.45.11.1638. [PMID: 8866573] - S C Blair, T M Greenaway, J M Bryson, J L Phuyal, V R Wensley, I D Caterson, G J Cooney. Hepatic gluconeogenesis and the activity of PDH in individual tissues of GTG-obese mice following adrenalectomy.
Obesity research.
1996 Jul; 4(4):367-75. doi:
10.1002/j.1550-8528.1996.tb00244.x. [PMID: 8822761] - S C Blair, I D Caterson, G J Cooney. Insulin response to a spontaneously ingested standard meal during the development of obesity in GTG-injected mice.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
1996 Apr; 20(4):319-23. doi:
NULL. [PMID: 8680458] - S C Blair, I D Caterson, G J Cooney. Glucose tolerance and insulin secretion after adrenalectomy in mice made obese with gold thioglucose.
The Journal of endocrinology.
1996 Mar; 148(3):391-8. doi:
10.1677/joe.0.1480391. [PMID: 8778217] - M Maffei, H Fei, G H Lee, C Dani, P Leroy, Y Zhang, R Proenca, R Negrel, G Ailhaud, J M Friedman. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.
Proceedings of the National Academy of Sciences of the United States of America.
1995 Jul; 92(15):6957-60. doi:
10.1073/pnas.92.15.6957. [PMID: 7624352] - S J Mandel, G A Brent, M Weinblatt, P R Larsen. Prospective studies of thyroid function in patients receiving gold therapy.
Thyroid : official journal of the American Thyroid Association.
1995 Apr; 5(2):113-6. doi:
10.1089/thy.1995.5.113. [PMID: 7647570] - S J Heydrick, N Gautier, C Olichon-Berthe, E Van Obberghen, Y Le Marchand-Brustel. Early alteration of insulin stimulation of PI 3-kinase in muscle and adipocyte from gold thioglucose obese mice.
The American journal of physiology.
1995 Apr; 268(4 Pt 1):E604-12. doi:
10.1152/ajpendo.1995.268.4.e604. [PMID: 7733258] - L Thunus, J F Dauphin, G Moiny, C Deby, G Deby-Dupont. Anti-inflammatory properties of copper, gold and silver, individually and as mixtures.
The Analyst.
1995 Mar; 120(3):967-73. doi:
10.1039/an9952000967. [PMID: 7741265] - C Chen, P F Williams, G J Cooney, I D Caterson. Changes in glycogen metabolism in liver of gold thioglucose injected mice during the development of obesity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
1994 Sep; 18(9):627-31. doi:
. [PMID: 7812417] - S ten Wolde, M Janssen, W van Duijn, C B Lamers, J Hermans, B A Dijkmans. No effect of intramuscular gold therapy on serological parameters of Helicobacter pylori infection in patients with rheumatoid arthritis: a 12 month prospective study.
Annals of the rheumatic diseases.
1994 Jun; 53(6):400-2. doi:
10.1136/ard.53.6.400. [PMID: 8037498] - S C Blair, I D Caterson, G J Cooney. Effect of adrenalectomy on glucose tolerance and lipid metabolism in gold-thioglucose obese mice.
The American journal of physiology.
1994 Jun; 266(6 Pt 1):E993-1000. doi:
10.1152/ajpendo.1994.266.6.e993. [PMID: 8023932] - U F Machado, I Shimizu, M Saito. Reduced content and preserved translocation of glucose transporter (GLUT 4) in white adipose tissue of obese mice.
Physiology & behavior.
1994 Apr; 55(4):621-5. doi:
10.1016/0031-9384(94)90035-3. [PMID: 8190786] - M Cormont, J F Tanti, E Van Obberghen, Y Le Marchand-Brustel. Expression of guanine-nucleotide-binding proteins in lean and obese insulin-resistant mice.
Molecular and cellular endocrinology.
1994 Mar; 99(2):169-76. doi:
10.1016/0303-7207(94)90005-1. [PMID: 8206324] - K S Steinbeck, I D Caterson, G J Cooney. Tissue [1-14C] 2-deoxyglucose metabolism in the gold thioglucose obese mouse: effects of 'dieting'.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
1994 Mar; 18(3):167-72. doi:
. [PMID: 8186814] - Y Eguchi, Y Uchigata, K Yao, H Yokoyama, Y Hirata, Y Omori. Longitudinal changes of serum insulin concentration and insulin antibody features in persistent insulin autoimmune syndrome (Hirata's disease).
Autoimmunity.
1994; 19(4):279-84. doi:
10.3109/08916939409071354. [PMID: 7578855] - J M Bryson, G J Cooney, V R Wensley, S C Blair, I D Caterson. Diurnal patterns of cardiac and hepatic pyruvate dehydrogenase complex activity in gold-thioglucose-obese mice.
The Biochemical journal.
1993 Nov; 295 ( Pt 3)(?):731-4. doi:
10.1042/bj2950731. [PMID: 8240285] - U F Machado, Y Shimizu, M Saito. Decreased glucose transporter (GLUT 4) content in insulin-sensitive tissues of obese aurothioglucose- and monosodium glutamate-treated mice.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
1993 Sep; 25(9):462-5. doi:
10.1055/s-2007-1002149. [PMID: 8225198] - Y S Kim, G F Combs. Effects of aurothioglucose and dietary Se on glutathione S-transferase activities and glutathione concentrations in chick tissues.
Biological trace element research.
1993 May; 37(2-3):165-77. doi:
10.1007/bf02783792. [PMID: 7688530] - R C Elder, Z Zhao, Y Zhang, J G Dorsey, E V Hess, K Tepperman. Dicyanogold (I) is a common human metabolite of different gold drugs.
The Journal of rheumatology.
1993 Feb; 20(2):268-72. doi:
NULL. [PMID: 8474063] - F Santini, I J Chopra, R E Hurd, G N Teco. A study of the characteristics of hepatic iodothyronine 5'-monodeiodinase in various vertebrate species.
Endocrinology.
1992 Aug; 131(2):830-4. doi:
10.1210/endo.131.2.1639026. [PMID: 1639026] - S D White, R A Rosychuk, T A Janik, P Denerolle, P Schultheiss. Plasma cell stomatitis-pharyngitis in cats: 40 cases (1973-1991).
Journal of the American Veterinary Medical Association.
1992 May; 200(9):1377-80. doi:
NULL. [PMID: 1601728] - F Santini, I J Chopra, R E Hurd, D H Solomon, G N Teco. A study of the characteristics of the rat placental iodothyronine 5-monodeiodinase: evidence that it is distinct from the rat hepatic iodothyronine 5'-monodeiodinase.
Endocrinology.
1992 Apr; 130(4):2325-32. doi:
10.1210/endo.130.4.1547744. [PMID: 1547744] - K Kita, M Furuse, S I Yang, J Okumura. Influence of dietary sorbose on lipogenesis in gold thioglucose-injected obese mice.
The International journal of biochemistry.
1992 Feb; 24(2):249-53. doi:
10.1016/0020-711x(92)90254-x. [PMID: 1733790] - K Yao, Y Uchigata, H Kyono, H Yokoyama, Y Eguchi, H Fukushima, K Yamauchi, Y Hirata. Human insulin-specific immunoglobulin G antibody and hypoglycemic attacks after the injection of gold thioglucose.
Journal of endocrinological investigation.
1992 Jan; 15(1):43-7. doi:
10.1007/bf03348654. [PMID: 1560190] - S C Blair, G J Cooney, G S Denyer, P F Williams, I D Caterson. Differences in lipogenesis in tissues of control and gold-thioglucose obese mice after an isocaloric meal.
Biochimica et biophysica acta.
1991 Oct; 1085(3):385-8. doi:
10.1016/0005-2760(91)90145-8. [PMID: 1911874] - M H Weber, A Ammon, M Oppermann, T von Rothkirch, F Scheler. [Panhypogammaglobulinemia: a rare complication of parenteral gold therapy].
Zeitschrift fur Rheumatologie.
1991 Jul; 50(4):207-10. doi:
NULL. [PMID: 1746169] - J Yamashita, S Hayashi. The effect of dietary protein source on plasma cholesterol level and fecal steroid excretion in obese mice.
Journal of nutritional science and vitaminology.
1990 Dec; 36(6):545-58. doi:
10.3177/jnsv.36.545. [PMID: 2097326] - T Iida, Y Hirata, H Takahashi, K Ikeda, S Nakagawa. Cardiac atrial natriuretic peptide concentrations in experimental obese mice.
Endocrinologia japonica.
1990 Oct; 37(5):703-7. doi:
10.1507/endocrj1954.37.703. [PMID: 2150810] - J B German, M L Hu. Oxidant stress inhibits the endogenous production of lipoxygenase metabolites in rat lungs and fish gills.
Free radical biology & medicine.
1990; 8(5):441-8. doi:
10.1016/0891-5849(90)90057-p. [PMID: 2123817] - M Wanic-Kossowska, I Turczak-Bierła, A Grzegorzewska. [2 cases of kidney damage during the treatment with gold preparations].
Przeglad lekarski.
1990; 47(11):788-90. doi:
NULL. [PMID: 2129137] - J Yamashita, Y Fujita, M Kamimura, S Hayashi. Different effects of soy protein on cholesterol metabolism in rats and mice.
Monographs on atherosclerosis.
1990; 16(?):36-43. doi:
NULL. [PMID: 2284016] - C Pace, C Delmo, R Lee. Altered electrical responses of B-cells after goldthioglucose-induced lesions in the ventromedial hypothalamus.
Research communications in chemical pathology and pharmacology.
1989 Sep; 65(3):401-4. doi:
. [PMID: 2510225] - H Watanabe. Pathogenesis of gastric mucosal damage induced by intraperitoneal administration of gold thioglucose in rats.
Gastroenterologia Japonica.
1989 Aug; 24(4):357-64. doi:
10.1007/bf02774340. [PMID: 2506094] - C J Ganley, S A Paget, M M Reidenberg. Increased renal tubular cell excretion by patients receiving chronic therapy with gold and with nonsteroidal anti-inflammatory drugs.
Clinical pharmacology and therapeutics.
1989 Jul; 46(1):51-5. doi:
10.1038/clpt.1989.106. [PMID: 2501058] - G J Cooney, M A Vanner, J L Nicks, P F Williams, I D Caterson. Changes in the lipogenic response to feeding of liver, white adipose tissue and brown adipose tissue during the development of obesity in the gold-thioglucose-injected mouse.
The Biochemical journal.
1989 May; 259(3):651-7. doi:
10.1042/bj2590651. [PMID: 2499313] - J K Beckman, H L Greene. Effects of aurothioglucose on iron-induced rat liver microsomal lipid peroxidation.
Lipids.
1988 Sep; 23(9):899-903. doi:
10.1007/bf02536212. [PMID: 3141731] - M L Hu, C J Dillard, A L Tappel. In vivo effects of aurothioglucose and sodium thioglucose on rat tissue sulfhydryl levels and plasma sulfhydryl reactivity.
Agents and actions.
1988 Aug; 25(1-2):132-8. doi:
10.1007/bf01969104. [PMID: 3142227] - M L Hu, C J Dillard, A L Tappel. Effect of chronic aurothioglucose treatment of rats on kidney catalase and cytochromes.
Journal of inorganic biochemistry.
1988 Jul; 33(3):175-81. doi:
10.1016/0162-0134(88)80047-3. [PMID: 3138383] - I D Caterson, A L Kerbey, G J Cooney, R Frankland, G S Denyer, J Nicks, P F Williams. Inactivation of pyruvate dehydrogenase complex in heart muscle mitochondria of gold-thioglucose-induced obese mice is not due to a stable increase in activity of pyruvate dehydrogenase kinase.
The Biochemical journal.
1988 Jul; 253(1):291-4. doi:
10.1042/bj2530291. [PMID: 3138985] - J L Roberts, F M Whittington, M Enser. Effects of litter size and subsequent gold-thioglucose-induced obesity on adipose tissue weight, distribution and cellularity in male and female mice: an age study.
The British journal of nutrition.
1988 May; 59(3):519-33. doi:
10.1079/bjn19880061. [PMID: 3134938] - M L Hu, A J Viljoen, A L Tappel. Interactions of gold with cytosolic selenium-containing proteins in rat kidney and liver.
Journal of inorganic biochemistry.
1988 Apr; 32(4):281-90. doi:
10.1016/0162-0134(88)85008-6. [PMID: 3132529] - M L Hu, C J Dillard, A L Tappel. Aurothioglucose effect on sulfhydryls and glutathione-metabolizing enzymes: in vivo inhibition of selenium-dependent glutathione peroxidase.
Research communications in chemical pathology and pharmacology.
1988 Feb; 59(2):147-60. doi:
. [PMID: 3128851] - Y Karasawa, Y Sugawa-Katayama, H Danbara. The effect of intraperitoneally administered gold thioglucose on growth, food consumption and accumulation of gold in various organs of the chicken (Gallus domesticus).
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
1988; 90(2):461-4. doi:
. [PMID: 2903007] - D R Haynes, I R Garrett, M W Whitehouse, B Vernon-Roberts. Do gold drugs inhibit interleukin-1? Evidence from an in vitro lymphocyte activating factor assay.
The Journal of rheumatology.
1988; 15(5):775-8. doi:
NULL. [PMID: 3139878] - T W Rooney, A Lorber, P Veng-Pedersen, R A Herman, R Meehan, J Hade, A Hade, D E Furst. Gold pharmacokinetics in breast milk and serum of a lactating woman.
The Journal of rheumatology.
1987 Dec; 14(6):1120-2. doi:
NULL. [PMID: 3125315] - J Wolters, P Frederik, H van Rie, E Zeppenfeldt. Minimal change nephropathy during gold treatment. A case with unusual histopathological and immunopathological features.
The Netherlands journal of medicine.
1987 Dec; 31(5-6):234-40. doi:
NULL. [PMID: 3124008] - K J McVety, Z A Shaikh. Subchronic treatment of rats with aurothioglucose; effects on plasma, hepatic, renal and urinary zinc, copper and metallothionein.
Toxicology.
1987 Nov; 46(3):295-306. doi:
10.1016/0300-483x(87)90210-1. [PMID: 3118513] - I D Caterson, L D Astbury, P F Williams, M A Vanner, G J Cooney, J R Turtle. The activity of the pyruvate dehydrogenase complex in heart and liver from mice during the development of obesity and insulin resistance.
The Biochemical journal.
1987 Apr; 243(2):549-53. doi:
10.1042/bj2430549. [PMID: 3115255] - C J Dillard, M L Hu, A L Tappel. Effect of aurothioglucose on glutathione and glutathione-metabolizing and related enzymes in rat liver and kidney.
Chemico-biological interactions.
1987; 64(1-2):103-14. doi:
10.1016/0009-2797(87)90064-0. [PMID: 3121194] - K Steinbeck, I D Caterson, L Astbury, J R Turtle. The effect of diet composition on weight gain and pyruvate dehydrogenase activity in heart muscle in the gold thioglucose obese mouse.
International journal of obesity.
1987; 11(5):507-18. doi:
. [PMID: 3123409] - F Massicot, R Falcou, F Heymans, J J Godfroid, M Apfelbaum. Effects of a new anorectic drug (PM 170) on development of gold thioglucose-induced obesity in mice.
General pharmacology.
1987; 18(3):249-52. doi:
10.1016/0306-3623(87)90007-3. [PMID: 3106136] - S D Mercurio, G F Combs. Synthetic seleno-organic compound with glutathione peroxidase-like activity in the chick.
Biochemical pharmacology.
1986 Dec; 35(24):4505-9. doi:
10.1016/0006-2952(86)90771-9. [PMID: 3098252] - K Steinbeck, I D Caterson, J R Turtle. The activity of the pyruvate dehydrogenase complex in heart muscle in the previously obese mouse model.
Bioscience reports.
1986 Dec; 6(12):1071-5. doi:
10.1007/bf01141029. [PMID: 3107627] - T B Leonard, M E Graichen, L J Dahm, J G Dent. Effects of the chrysotherapeutic agents auranofin and gold sodium thiomalate on hepatic and renal drug metabolism and heme metabolism.
Biochemical pharmacology.
1986 Sep; 35(18):3057-63. doi:
10.1016/0006-2952(86)90386-2. [PMID: 3092830] - S D Mercurio, G F Combs. Selenium-dependent glutathione peroxidase inhibitors increase toxicity of prooxidant compounds in chicks.
The Journal of nutrition.
1986 Sep; 116(9):1726-34. doi:
10.1093/jn/116.9.1726. [PMID: 3093647] - M A Baker, A L Tappel. Effects of ligands on gold inhibition of selenium glutathione peroxidase.
Biochemical pharmacology.
1986 Jul; 35(14):2417-22. doi:
10.1016/0006-2952(86)90470-3. [PMID: 3089231] - A E von dem Borne, J G Pegels, R J van der Stadt, C M van der Plas-van Dalen, F M Helmerhorst. Thrombocytopenia associated with gold therapy: a drug-induced autoimmune disease?.
British journal of haematology.
1986 Jul; 63(3):509-16. doi:
10.1111/j.1365-2141.1986.tb07528.x. [PMID: 3089270] - W Paska, K J McDonald, M Croft. Studies on type II collagen induced arthritis in mice.
Agents and actions.
1986 Jun; 18(3-4):413-20. doi:
10.1007/bf01965006. [PMID: 3092598] - R M Snyder, C K Mirabelli, S T Crooke. Cellular association, intracellular distribution, and efflux of auranofin via sequential ligand exchange reactions.
Biochemical pharmacology.
1986 Mar; 35(6):923-32. doi:
10.1016/0006-2952(86)90078-x. [PMID: 3082334] - K L Blocka, H E Paulus, D E Furst. Clinical pharmacokinetics of oral and injectable gold compounds.
Clinical pharmacokinetics.
1986 Mar; 11(2):133-43. doi:
10.2165/00003088-198611020-00003. [PMID: 3082559] - C S Tse, A F Debons. Anorexia after adrenalectomy in gold thioglucose-treated obese mice: role of adipose tissue mass.
Physiology & behavior.
1986; 38(1):105-10. doi:
10.1016/0031-9384(86)90139-3. [PMID: 3097685] - W Blech, B Bierwolf, I Weiss, M Ziegler. [In vitro and in vivo effect of gold thioglucose on the insulin- and glucagon-secretion of the isolated perfused rat pancreas].
Biomedica biochimica acta.
1986; 45(4):507-22. doi:
. [PMID: 3085662] - A F Debons, C S Tse, L D Zurek, S Abrahamsen, L A Maayan. Adrenalectomy induced anorexia in gold thioglucose-treated obese mice: metabolic and hormonal changes.
Physiology & behavior.
1986; 38(1):111-7. doi:
10.1016/0031-9384(86)90140-x. [PMID: 3097686] - J M Katz, D H Gray. The in vitro effect of gold complexes on bone resorption.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
1986; 4(2):188-93. doi:
10.1002/jor.1100040207. [PMID: 3086527] - Y Kawano-Takahashi, H Ohminami, H Okuda, I Kitagawa, M Yoshikawa, S Arichi, T Hayashi. Effect of soya saponins on gold thioglucose (GTG)-induced obesity in mice.
International journal of obesity.
1986; 10(4):293-302. doi:
. [PMID: 3095255] - R Behrens, M Devereaux, B Hazleman, K Szaz, J Calvin, G Neale. Investigation of auranofin-induced diarrhoea.
Gut.
1986 Jan; 27(1):59-65. doi:
10.1136/gut.27.1.59. [PMID: 3081411] - F Fantini, F Cottafava, A Martini, M Murelli, E Franchini, R D'Errico, R Panzarasa. Changes of immunological parameters during auranofin treatment in children affected with juvenile chronic arthritis.
International journal of clinical pharmacology research.
1986; 6(1):61-7. doi:
NULL. [PMID: 3082775] - I R Garrett, M W Whitehouse, B Vernon-Roberts, P M Brooks. Ambivalent properties of gold drugs in adjuvant induced polyarthritis in rats.
The Journal of rheumatology.
1985 Dec; 12(6):1079-82. doi:
NULL. [PMID: 3937896] - S D Mercurio, G F Combs. Drug-induced changes in selenium-dependent glutathione peroxidase activity in the chick.
The Journal of nutrition.
1985 Nov; 115(11):1459-70. doi:
10.1093/jn/115.11.1459. [PMID: 3932615] - R A Cuperus, A O Muijsers, R Wever. Antiarthritic drugs containing thiol groups scavenge hypochlorite and inhibit its formation by myeloperoxidase from human leukocytes. A therapeutic mechanism of these drugs in rheumatoid arthritis?.
Arthritis and rheumatism.
1985 Nov; 28(11):1228-33. doi:
10.1002/art.1780281106. [PMID: 2998407] - M Enser, J Roberts, F Whittington. Effect of gold thioglucose-induced obesity on adipose tissue weight and cellularity in male and female mice suckled in large and small litters: investigations into sex differences and site differences.
The British journal of nutrition.
1985 Nov; 54(3):645-54. doi:
10.1079/bjn19850151. [PMID: 3939690] - D Pham Huy, M Roch-Arveiller, O Muntaner, J P Giroud. In vitro and in vivo effects of gold salts on chemotaxis and random migration of rat polymorphonuclear leucocytes.
Agents and actions.
1985 Jul; 16(5):363-8. doi:
10.1007/bf01982874. [PMID: 3931441] - A Glennås. Auranofin treatment of rats: adaptation to intestinal adverse effects and observations on the cytosolic distribution of gold in the intestines, liver and kidneys.
Acta pharmacologica et toxicologica.
1985 May; 56(5):404-9. doi:
10.1111/j.1600-0773.1985.tb01310.x. [PMID: 3929564] - J J Gonzales, M S Bohrer, J T Edelson, A M Fendrick, M F Morrison. Proteinuria and oral gold treatment.
Annals of internal medicine.
1985 Apr; 102(4):561-2. doi:
10.7326/0003-4819-102-4-561. [PMID: 3919633]
