Fluticasone (BioDeep_00000006607)

   


代谢物信息卡片


Fluticasone

化学式: C22H27F3O4S (444.1582)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(not specific) 50%

分子结构信息

SMILES: CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)SCF)O)C)O)F)C)F
InChI: InChI=1S/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

描述信息

R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BA - Glucocorticoids
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii)
R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D000893 - Anti-Inflammatory Agents
D018926 - Anti-Allergic Agents
D003879 - Dermatologic Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

3 个代谢物同义名

Fluticasone; BCP31287; Fluticasone



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ALB, CCL5, CYP3A4, IL13, POMC
Endosome membrane 1 ADRB2
Endoplasmic reticulum membrane 2 CD4, CYP3A4
Nucleus 3 ADRB2, ALB, ARID3B
cytosol 1 ALB
centrosome 1 ALB
nucleoplasm 1 ARID3B
Cell membrane 5 ADRB2, CD4, CD8A, KIT, TNF
Multi-pass membrane protein 2 ADRB2, ATP4A
cell surface 1 TNF
Golgi apparatus 2 ADRB2, ALB
neuronal cell body 1 TNF
Lysosome 1 ADRB2
acrosomal vesicle 1 KIT
endosome 1 ADRB2
plasma membrane 7 ADRB2, ATP4A, CD4, CD8A, IGHE, KIT, TNF
Membrane 4 ADRB2, ATP4A, CYP3A4, KIT
apical plasma membrane 2 ADRB2, ATP4A
extracellular exosome 1 ALB
endoplasmic reticulum 1 ALB
extracellular space 15 ALB, ATP4A, CCL5, CRP, CXCL10, CXCL8, IGHE, IL13, IL4, IL5, IL6, KIT, POMC, RNASE3, TNF
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 1 CYP3A4
Microsome membrane 1 CYP3A4
Single-pass type I membrane protein 4 CD4, CD8A, IGHE, KIT
Secreted 10 ALB, CCL5, CRP, CXCL10, CXCL8, IL13, IL4, IL5, IL6, POMC
extracellular region 14 ALB, CCL5, CD8A, CRP, CXCL10, CXCL8, IGHE, IL13, IL4, IL5, IL6, POMC, RNASE3, TNF
cytoplasmic side of plasma membrane 1 KIT
[Isoform 2]: Secreted 1 CD8A
anchoring junction 1 ALB
external side of plasma membrane 6 CD4, CD8A, CXCL10, IL13, KIT, TNF
Early endosome 2 ADRB2, CD4
cell-cell junction 1 KIT
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 ATP4A
Membrane raft 2 CD4, TNF
secretory granule 1 POMC
receptor complex 3 ADRB2, CD8A, KIT
ciliary basal body 1 ALB
IgE immunoglobulin complex 1 IGHE
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
[Isoform 2]: Cell membrane 1 IGHE
fibrillar center 1 KIT
[Isoform 3]: Cytoplasm 1 KIT
plasma membrane raft 1 CD8A
secretory granule lumen 1 POMC
endoplasmic reticulum lumen 3 ALB, CD4, IL6
platelet alpha granule lumen 1 ALB
azurophil granule lumen 1 RNASE3
neuronal dense core vesicle 1 ADRB2
clathrin-coated endocytic vesicle membrane 2 ADRB2, CD4
[Isoform 1]: Cell membrane 1 CD8A
[Isoform 3]: Cell membrane 1 IGHE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 2 CD4, CD8A
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
interleukin-6 receptor complex 1 IL6
potassium:proton exchanging ATPase complex 1 ATP4A
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Hua Li, Tao Dong, Jinling Luan. Efficacy and safety of fluticasone propionate/salmeterol and fluticasone propionate monotherapy in step-up treatment of childhood asthma: A systematic review and meta-analysis. Heart & lung : the journal of critical care. 2023 Sep; 63(?):23-34. doi: 10.1016/j.hrtlng.2023.09.004. [PMID: 37740997]
  • Yiwen Gong, Zichao Sui, Yinghua Lv, Qingshan Zheng, Lujin Li. LABA/LAMA versus LABA/ICS fixed-dose combinations in the prevention of COPD exacerbations: a modeling analysis of literature aggregate data. European journal of clinical pharmacology. 2023 Jul; ?(?):. doi: 10.1007/s00228-023-03543-y. [PMID: 37507595]
  • Haoxiang Zhu, Hongxia Liu, Zichao Sui, Jiesen Yu, Qingshan Zheng, Lujin Li. Quantitative comparison of different inhaled corticosteroids in the treatment of asthma in children. Pediatric research. 2023 01; 93(1):31-38. doi: 10.1038/s41390-022-02095-8. [PMID: 35545660]
  • Peter Daley-Yates, Brian Keppler, Amanda Baines, George Bardsley, James Fingleton. Metabolomic changes related to airway inflammation, asthma pathogenesis and systemic activity following inhaled fluticasone furoate/vilanterol: a randomized controlled trial. Respiratory research. 2022 Sep; 23(1):258. doi: 10.1186/s12931-022-02164-w. [PMID: 36127726]
  • Matthew W McCarthy. Fluticasone propionate as a potential treatment for COVID-19. Drugs of today (Barcelona, Spain : 1998). 2022 May; 58(5):241-247. doi: 10.1358/dot.2022.58.5.3381591. [PMID: 35535815]
  • Yuanfeng Shen, Entezar Mehrabi Nasab, Fatemeh Hassanpour, Seyyed Shamsadin Athari. The Effects of Combined Therapeutic Protocol on Allergic Rhinitis Symptoms and Molecular Determinants. Iranian journal of allergy, asthma, and immunology. 2022 Apr; 21(2):141-150. doi: 10.18502/ijaai.v21i2.9222. [PMID: 35490268]
  • Ying Zhong, Lujin Li, Rui Chen, Qingshan Zheng. Quantitative comparison of dose-effect and time-course of fluticasone furoate and fluticasone propionate in adult and adolescent patients with persistent asthma: A systematic review and meta-analysis. Respirology (Carlton, Vic.). 2022 03; 27(3):194-201. doi: 10.1111/resp.14203. [PMID: 35043513]
  • Qi Fan, Yixuan Feng, Yan Hou, Feihu Wu, Wei Zhang, Wenbin Nie, Bin Li, Zhongyu Zhou, Wenbin Fu, Lei Shi, Zhongren Sun, Hong Zhao. Effect of acupuncture therapy combined with fluticasone propionate in the treatment of persistent allergic rhinitis: study protocol for a randomized controlled trial. Trials. 2022 Jan; 23(1):94. doi: 10.1186/s13063-022-06020-6. [PMID: 35101086]
  • Jiachun Li, Ziliang Huang, Keying Li, Xiaoyun Jian, Binghui Liang. Study on the Effect of Self-Made Lifei Dingchuan Decoction Combined with Western Medicine on Cough Variant Asthma. Computational and mathematical methods in medicine. 2022; 2022(?):9803552. doi: 10.1155/2022/9803552. [PMID: 36132547]
  • Fahad H Alahmadi, Brian Keevil, Lynn Elsey, Kate George, Robert Niven, Stephen J Fowler. Serum Inhaled Corticosteroid Detection for Monitoring Adherence in Severe Asthma. The journal of allergy and clinical immunology. In practice. 2021 12; 9(12):4279-4287.e6. doi: 10.1016/j.jaip.2021.05.041. [PMID: 34153519]
  • Muhammad Waqas Sadiq, Olaf Holz, Birthe D Ellinghusen, Cornelia Faulenbach, Meike Müller, Philipp Badorrek, Ulf G Eriksson, Markus Fridén, Stina Stomilovic, Anders J Lundqvist, Jens M Hohlfeld. Lung pharmacokinetics of inhaled and systemic drugs: A clinical evaluation. British journal of pharmacology. 2021 11; 178(22):4440-4451. doi: 10.1111/bph.15621. [PMID: 34250588]
  • Ravneet Ravinder Verma, Nitin Gupta, Mugdha Singh. Letter to the editor regarding "The outcome of fluticasone nasal spray on anosmia and triamcinolone oral paste in dysgeusia in COVID-19 patients". American journal of otolaryngology. 2021 Sep; 42(5):103103. doi: 10.1016/j.amjoto.2021.103103. [PMID: 34116850]
  • Pär Ewing, Steven Oag, Anders Lundqvist, Stina Stomilovic, Ida Stellert, Malin Antonsson, Sandro Filipe Nunes, Patrik U Andersson, Ulrika Tehler, Carl Sjöberg, AnnaMaria Péterffy, Per Gerde. Airway Epithelial Lining Fluid and Plasma Pharmacokinetics of Inhaled Fluticasone Propionate and Salmeterol Xinafoate in Mechanically Ventilated Pigs. Journal of aerosol medicine and pulmonary drug delivery. 2021 08; 34(4):231-241. doi: 10.1089/jamp.2020.1637. [PMID: 33216656]
  • Panagiotis Sakellariou, Michael Petrou, Emmanouil Lyris, Maria Tsivou, Argyro Fragkaki, Polyxeni Kiousi, Yiannis S Angelis, Constantinos Pistos. Determination of salmeterol, α-hydroxysalmeterol and fluticasone propionate in human urine and plasma for doping control using UHPLC-QTOF-MS. Biomedical chromatography : BMC. 2021 Aug; 35(8):e5114. doi: 10.1002/bmc.5114. [PMID: 33720401]
  • Jerome R Lechien, Cosima C Hoch, Luigi A Vaira, Sven Saussez. The interest of fluticasone nasal spray in COVID-19 related anosmia is still not demonstrated. American journal of otolaryngology. 2021 Jul; 42(4):103008. doi: 10.1016/j.amjoto.2021.103008. [PMID: 33810883]
  • Chandra Veer Singh, Shraddha Jain, Sana Parveen, Prasad Deshmukh. The outcome of fluticasone nasal spray on anosmia and triamcinolone oral paste in taste dysgeusia in COVID-19 patients. American journal of otolaryngology. 2021 Jul; 42(4):103009. doi: 10.1016/j.amjoto.2021.103009. [PMID: 33846030]
  • Chandra Veer Singh, Shraddha Jain, Sana Parveen. The outcome of fluticasone nasal spray on anosmia and triamcinolone oral paste in dysgeusia in COVID-19 patients. American journal of otolaryngology. 2021 May; 42(3):102892. doi: 10.1016/j.amjoto.2020.102892. [PMID: 33493729]
  • Mohamed H Desoqi, Hossam S El-Sawy, Elsayed Kafagy, Mamdouh Ghorab, Shadeed Gad. Fluticasone propionate-loaded solid lipid nanoparticles with augmented anti-inflammatory activity: optimisation, characterisation and pharmacodynamic evaluation on rats. Journal of microencapsulation. 2021 May; 38(3):177-191. doi: 10.1080/02652048.2021.1887383. [PMID: 33583315]
  • Deepa K Ingawale, Satish K Mandlik, Snehal S Patel. Hecogenin and fluticasone combination attenuates TNBS-induced ulcerative colitis in rats via downregulation of pro-inflammatory mediators and oxidative stress. Immunopharmacology and immunotoxicology. 2021 Apr; 43(2):160-170. doi: 10.1080/08923973.2021.1872617. [PMID: 33435764]
  • M A Rahman, M N Hasan, M A Rahim, S Ahmed, S P Munni, M K Adhikari, M J Uddin, K M Saif-Ur-Rahman. Glycaemic Status of Asthma Patients Using Inhaled Fluticasone. Mymensingh medical journal : MMJ. 2021 Apr; 30(2):274-280. doi: NULL. [PMID: 33830103]
  • Megan L Zilla, Christian Keetch, Gretchen Mitchell, Jeffery McBreen, Michael R Shurin, Sarah E Wheeler. SARS-CoV-2 Serologic Immune Response in Exogenously Immunosuppressed Patients. The journal of applied laboratory medicine. 2021 03; 6(2):486-490. doi: 10.1093/jalm/jfaa232. [PMID: 33367709]
  • Peter Daley-Yates, Noushin Brealey, Sebin Thomas, Daren Austin, Shaila Shabbir, Tim Harrison, Dave Singh, Neil Barnes. Therapeutic index of inhaled corticosteroids in asthma: A dose-response comparison on airway hyperresponsiveness and adrenal axis suppression. British journal of clinical pharmacology. 2021 02; 87(2):483-493. doi: 10.1111/bcp.14406. [PMID: 32484940]
  • Michael Verschoor-Kirss, Elizabeth A Rozanski, Claire R Sharp, Trisha J Oura, Ashley Egan, Perry Bain, Joyce Knoll. Treatment of naturally occurring asthma with inhaled fluticasone or oral prednisolone: A randomized pilot trial. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2021 Jan; 85(1):61-67. doi: . [PMID: 33390654]
  • Akira Nakazono, Yuji Nakamaru, Mahnaz Ramezanpour, Takeshi Kondo, Masashi Watanabe, Shigetsugu Hatakeyama, Shogo Kimura, Aya Honma, P J Wormald, Sarah Vreugde, Masanobu Suzuki, Akihiro Homma. Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells. Frontiers in cellular and infection microbiology. 2021; 11(?):655666. doi: 10.3389/fcimb.2021.655666. [PMID: 33981629]
  • Gail M Comer, Mark A Bush, Evan S Dellon, Mark T Marino. Effect of Food Intake and Body Position on the Pharmacokinetics of Swallowed APT-1011, a Fluticasone Orally Disintegrating Tablet, in Healthy Adult Volunteers. Journal of clinical pharmacology. 2020 06; 60(6):734-743. doi: 10.1002/jcph.1572. [PMID: 31943257]
  • Joana Figueiredo, Margarida Serrado, Nikita Khmelinskii, Sónia do Vale. Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir. BMJ case reports. 2020 May; 13(5):. doi: 10.1136/bcr-2019-233712. [PMID: 32467117]
  • Johanna Eriksson, Erik Sjögren, Hans Lennernäs, Helena Thörn. Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption. The AAPS journal. 2020 05; 22(3):71. doi: 10.1208/s12248-020-00456-x. [PMID: 32394314]
  • Deepa K Ingawale, Satish K Mandlik, Snehal S Patel. Combination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model. Immunopharmacology and immunotoxicology. 2020 Apr; 42(2):128-137. doi: 10.1080/08923973.2020.1728541. [PMID: 32070162]
  • Jingyi Zhao, Xinyu Yan, Jianqing Gai, Jinshuai Han, Hong Zhang, Hui Luo, Shaoting Huang, Junge Wang. Efficacy of Bimin decoction for patients with perennial allergic rhinitis: an open-label non-inferiority randomized controlled trial. Trials. 2019 Dec; 20(1):802. doi: 10.1186/s13063-019-3763-z. [PMID: 31888713]
  • Tao-Tao Fu, Zhao-Qing Cong, Yun Zhao, Wei-Ya Chen, Chun-Yu Liu, Ying Zheng, Fei-Fei Yang, Yong-Hong Liao. Fluticasone propionate nanosuspensions for sustained nebulization delivery: An in vitro and in vivo evaluation. International journal of pharmaceutics. 2019 Dec; 572(?):118839. doi: 10.1016/j.ijpharm.2019.118839. [PMID: 31715359]
  • Omar Usmani, Nicolas Roche, Jonathan Marshall, Helen Danagher, David Price. An innovative corticosteroid/long-acting β2-agonist breath-triggered inhaler: facilitating lung delivery of fluticasone propionate/formoterol fumarate for the treatment of asthma. Expert opinion on drug delivery. 2019 12; 16(12):1367-1380. doi: 10.1080/17425247.2019.1689957. [PMID: 31752560]
  • Yan Li, Huafang Li, Yucheng Sheng, Xin Du, Yuhui Yao, Xian Luo, Peiming Ma. Pharmacokinetics of Single and Repeat Doses of Fluticasone Furoate/Umeclidinium/Vilanterol in Healthy Chinese Adults. Clinical pharmacology in drug development. 2019 08; 8(6):721-733. doi: 10.1002/cpdd.626. [PMID: 30427594]
  • Syedsaoud Zaidi, Mong-Jen Chen, Daniel T Lee, Elsa Neubart, Pär Ewing, Anna Miller-Larsson, Günther Hochhaus. Fetal Concentrations of Budesonide and Fluticasone Propionate: a Study in Mice. The AAPS journal. 2019 04; 21(4):53. doi: 10.1208/s12248-019-0313-2. [PMID: 30993489]
  • Alan Getgood, Aad Dhollander, Amanda Malone, James Price, James Helliwell. Pharmacokinetic Profile of Intra-articular Fluticasone Propionate Microparticles in Beagle Dog Knees. Cartilage. 2019 04; 10(2):139-147. doi: 10.1177/1947603517723687. [PMID: 28786292]
  • Mireille Hassoun, Maria Malmlöf, Otto Scheibelhofer, Abhinav Kumar, Sukhi Bansal, Ewa Selg, Mattias Nowenwik, Per Gerde, Snezana Radivojev, Amrit Paudel, Sumit Arora, Ben Forbes. Use of PBPK Modeling To Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products. Molecular pharmaceutics. 2019 03; 16(3):1245-1254. doi: 10.1021/acs.molpharmaceut.8b01200. [PMID: 30640475]
  • Denise Wayne, Harald Iverson, Michael Gillespie, Edward Hellriegel, Calvin Small. Bioequivalence of fluticasone propionate and salmeterol (FS) given by the FS Spiromax® and Seretide Accuhaler® systems
. International journal of clinical pharmacology and therapeutics. 2019 Jan; 57(1):43-54. doi: 10.5414/cp203216. [PMID: 30431426]
  • Hui Wang, Penny Tan, David Barona, Grace Li, Susan Hoe, David Lechuga-Ballesteros, David S Nobes, Reinhard Vehring. Characterization of the suspension stability of pharmaceuticals using a shadowgraphic imaging method. International journal of pharmaceutics. 2018 Sep; 548(1):128-138. doi: 10.1016/j.ijpharm.2018.06.053. [PMID: 29959088]
  • Jean Bousquet, Eli O Meltzer, Peter Couroux, Arkady Koltun, Ferdinand Kopietz, Ullrich Munzel, Hans Christian Kuhl, Duc Tung Nguyen, Anne Marie Salapatek, David Price. Onset of Action of the Fixed Combination Intranasal Azelastine-Fluticasone Propionate in an Allergen Exposure Chamber. The journal of allergy and clinical immunology. In practice. 2018 Sep; 6(5):1726-1732.e6. doi: 10.1016/j.jaip.2018.01.031. [PMID: 29425904]
  • Ole D Wolthers, Sabine Mersmann, Sanjeeva Dissanayake. A Pilot Study of the Normative Range of Overnight Urinary Free Cortisol Corrected for Creatinine in Children. Clinical drug investigation. 2018 Apr; 38(4):313-318. doi: 10.1007/s40261-017-0609-x. [PMID: 29256049]
  • Vishal S Patel, Evan Walgama, Alkis Psaltis, Francois Lavigne, Steven D Pletcher, Peter H Hwang. Biocompatibility and pharmacokinetics of fluticasone-eluting sinus implant in a rabbit model. American journal of rhinology & allergy. 2017 Nov; 31(6):382-388. doi: 10.2500/ajra.2017.31.4481. [PMID: 29122083]
  • Erika Amore, Maria Ferraro, Maria Letizia Manca, Mark Gjomarkaj, Gaetano Giammona, Elisabetta Pace, Maria Luisa Bondì. Mucoadhesive solid lipid microparticles for controlled release of a corticosteroid in the chronic obstructive pulmonary disease treatment. Nanomedicine (London, England). 2017 Oct; 12(19):2287-2302. doi: 10.2217/nnm-2017-0072. [PMID: 28868971]
  • Gwijde F J P M Adriaensen, Keng-Hua Lim, Wytske J Fokkens. Safety and efficacy of a bioabsorbable fluticasone propionate-eluting sinus dressing in postoperative management of endoscopic sinus surgery: a randomized clinical trial. International forum of allergy & rhinology. 2017 08; 7(8):813-820. doi: 10.1002/alr.21963. [PMID: 28558147]
  • Eric A Pasman, Theresa A Heifert, Cade M Nylund. Esophageal squamous papillomas with focal dermal hypoplasia and eosinophilic esophagitis. World journal of gastroenterology. 2017 Mar; 23(12):2246-2250. doi: 10.3748/wjg.v23.i12.2246. [PMID: 28405153]
  • Lin Lin, Zhongchun Chen, Yitan Cao, Guangbin Sun. Normal saline solution nasal-pharyngeal irrigation improves chronic cough associated with allergic rhinitis. American journal of rhinology & allergy. 2017 Mar; 31(2):96-104. doi: 10.2500/ajra.2017.31.4418. [PMID: 28452705]
  • Ludger Klimek, Sophia C Poletti, Annette Sperl, Magdalena Spielhaupter, Cornel Bardenhewer, Joaquim Mullol, Karl Hörmann, Thomas Hummel. Olfaction in patients with allergic rhinitis: an indicator of successful MP-AzeFlu therapy. International forum of allergy & rhinology. 2017 03; 7(3):287-292. doi: 10.1002/alr.21877. [PMID: 27888645]
  • Sneha G Nair, Daxesh P Patel, Mallika Sanyal, Puran Singhal, Pranav S Shrivastav. Simultaneous analysis of glucocorticosteroid fluticasone propionate and its metabolite fluticasone propionate 17β-carboxylic acid in human plasma by UPLC-MS/MS at sub pg/mL level. Journal of pharmaceutical and biomedical analysis. 2017 Feb; 135(?):1-7. doi: 10.1016/j.jpba.2016.12.008. [PMID: 27987390]
  • D K Ingawale, S S Patel. Anti-Inflammatory Potential of Hecogenin in Experimental Animals: Possible Involvement of Inflammatory Cytokines and Myeloperoxidase. Drug research. 2016 Dec; 66(12):644-656. doi: 10.1055/s-0042-113184. [PMID: 27684191]
  • Alejandra Cimato, Andres Hoyos Obando, Graciela Facorro, María Martínez Sarrasague. Analysis of the structure and surfactant activity of novel formulations containing exogenous pulmonary surfactant and glucocorticoids. Respiratory physiology & neurobiology. 2016 11; 233(?):33-40. doi: 10.1016/j.resp.2016.07.009. [PMID: 27476933]
  • Yehonatan Pasternak, Havatzelet Yarden-Bilavsky, Yona Kodman, Meira Zoldan, Hannah Tamary, Shai Ashkenazi. Inhaled corticosteroids increase blood neutrophil count by decreasing the expression of neutrophil adhesion molecules Mac-1 and L-selectin. The American journal of emergency medicine. 2016 Oct; 34(10):1977-1981. doi: 10.1016/j.ajem.2016.07.003. [PMID: 27498916]
  • Shima Vazifehkah, Mohammad Reza Shams-Ardekani, Mohammad Kamalinejad, Seyed Mousa Saderhossein, Hamed Hosseini, Seyed Mohammad Shams, Shirin Abbassi, Sareh Eghtesad, Babak Saedi. Evaluation of a novel natural drop for treatment of chronic rhinosinusitis without nasal polyps: a single blind randomized trial. International forum of allergy & rhinology. 2016 09; 6(9):943-9. doi: 10.1002/alr.21785. [PMID: 27218285]
  • George Marshall. Falling up stairs. Australian family physician. 2016 Sep; 45(9):658-9. doi: NULL. [PMID: 27606369]
  • Andrzej Emeryk, Rabih Klink, Tammy McIver, Prashant Dalvi. A 12-week open-label, randomized, controlled trial and 24-week extension to assess the efficacy and safety of fluticasone propionate/formoterol in children with asthma. Therapeutic advances in respiratory disease. 2016 08; 10(4):324-37. doi: 10.1177/1753465816646320. [PMID: 27185164]
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