Fluticasone (BioDeep_00000006607)

   


代谢物信息卡片


Fluticasone

化学式: C22H27F3O4S (444.1582058000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)SCF)O)C)O)F)C)F
InChI: InChI=1S/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

描述信息

R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BA - Glucocorticoids
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii)
R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D000893 - Anti-Inflammatory Agents
D018926 - Anti-Allergic Agents
D003879 - Dermatologic Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

2 个代谢物同义名

Fluticasone; BCP31287



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hua Li, Tao Dong, Jinling Luan. Efficacy and safety of fluticasone propionate/salmeterol and fluticasone propionate monotherapy in step-up treatment of childhood asthma: A systematic review and meta-analysis. Heart & lung : the journal of critical care. 2023 Sep; 63(?):23-34. doi: 10.1016/j.hrtlng.2023.09.004. [PMID: 37740997]
  • Yiwen Gong, Zichao Sui, Yinghua Lv, Qingshan Zheng, Lujin Li. LABA/LAMA versus LABA/ICS fixed-dose combinations in the prevention of COPD exacerbations: a modeling analysis of literature aggregate data. European journal of clinical pharmacology. 2023 Jul; ?(?):. doi: 10.1007/s00228-023-03543-y. [PMID: 37507595]
  • Haoxiang Zhu, Hongxia Liu, Zichao Sui, Jiesen Yu, Qingshan Zheng, Lujin Li. Quantitative comparison of different inhaled corticosteroids in the treatment of asthma in children. Pediatric research. 2023 01; 93(1):31-38. doi: 10.1038/s41390-022-02095-8. [PMID: 35545660]
  • Peter Daley-Yates, Brian Keppler, Amanda Baines, George Bardsley, James Fingleton. Metabolomic changes related to airway inflammation, asthma pathogenesis and systemic activity following inhaled fluticasone furoate/vilanterol: a randomized controlled trial. Respiratory research. 2022 Sep; 23(1):258. doi: 10.1186/s12931-022-02164-w. [PMID: 36127726]
  • Matthew W McCarthy. Fluticasone propionate as a potential treatment for COVID-19. Drugs of today (Barcelona, Spain : 1998). 2022 May; 58(5):241-247. doi: 10.1358/dot.2022.58.5.3381591. [PMID: 35535815]
  • Yuanfeng Shen, Entezar Mehrabi Nasab, Fatemeh Hassanpour, Seyyed Shamsadin Athari. The Effects of Combined Therapeutic Protocol on Allergic Rhinitis Symptoms and Molecular Determinants. Iranian journal of allergy, asthma, and immunology. 2022 Apr; 21(2):141-150. doi: 10.18502/ijaai.v21i2.9222. [PMID: 35490268]
  • Ying Zhong, Lujin Li, Rui Chen, Qingshan Zheng. Quantitative comparison of dose-effect and time-course of fluticasone furoate and fluticasone propionate in adult and adolescent patients with persistent asthma: A systematic review and meta-analysis. Respirology (Carlton, Vic.). 2022 03; 27(3):194-201. doi: 10.1111/resp.14203. [PMID: 35043513]
  • Qi Fan, Yixuan Feng, Yan Hou, Feihu Wu, Wei Zhang, Wenbin Nie, Bin Li, Zhongyu Zhou, Wenbin Fu, Lei Shi, Zhongren Sun, Hong Zhao. Effect of acupuncture therapy combined with fluticasone propionate in the treatment of persistent allergic rhinitis: study protocol for a randomized controlled trial. Trials. 2022 Jan; 23(1):94. doi: 10.1186/s13063-022-06020-6. [PMID: 35101086]
  • Jiachun Li, Ziliang Huang, Keying Li, Xiaoyun Jian, Binghui Liang. Study on the Effect of Self-Made Lifei Dingchuan Decoction Combined with Western Medicine on Cough Variant Asthma. Computational and mathematical methods in medicine. 2022; 2022(?):9803552. doi: 10.1155/2022/9803552. [PMID: 36132547]
  • Fahad H Alahmadi, Brian Keevil, Lynn Elsey, Kate George, Robert Niven, Stephen J Fowler. Serum Inhaled Corticosteroid Detection for Monitoring Adherence in Severe Asthma. The journal of allergy and clinical immunology. In practice. 2021 12; 9(12):4279-4287.e6. doi: 10.1016/j.jaip.2021.05.041. [PMID: 34153519]
  • Muhammad Waqas Sadiq, Olaf Holz, Birthe D Ellinghusen, Cornelia Faulenbach, Meike Müller, Philipp Badorrek, Ulf G Eriksson, Markus Fridén, Stina Stomilovic, Anders J Lundqvist, Jens M Hohlfeld. Lung pharmacokinetics of inhaled and systemic drugs: A clinical evaluation. British journal of pharmacology. 2021 11; 178(22):4440-4451. doi: 10.1111/bph.15621. [PMID: 34250588]
  • Ravneet Ravinder Verma, Nitin Gupta, Mugdha Singh. Letter to the editor regarding "The outcome of fluticasone nasal spray on anosmia and triamcinolone oral paste in dysgeusia in COVID-19 patients". American journal of otolaryngology. 2021 Sep; 42(5):103103. doi: 10.1016/j.amjoto.2021.103103. [PMID: 34116850]
  • Pär Ewing, Steven Oag, Anders Lundqvist, Stina Stomilovic, Ida Stellert, Malin Antonsson, Sandro Filipe Nunes, Patrik U Andersson, Ulrika Tehler, Carl Sjöberg, AnnaMaria Péterffy, Per Gerde. Airway Epithelial Lining Fluid and Plasma Pharmacokinetics of Inhaled Fluticasone Propionate and Salmeterol Xinafoate in Mechanically Ventilated Pigs. Journal of aerosol medicine and pulmonary drug delivery. 2021 08; 34(4):231-241. doi: 10.1089/jamp.2020.1637. [PMID: 33216656]
  • Panagiotis Sakellariou, Michael Petrou, Emmanouil Lyris, Maria Tsivou, Argyro Fragkaki, Polyxeni Kiousi, Yiannis S Angelis, Constantinos Pistos. Determination of salmeterol, α-hydroxysalmeterol and fluticasone propionate in human urine and plasma for doping control using UHPLC-QTOF-MS. Biomedical chromatography : BMC. 2021 Aug; 35(8):e5114. doi: 10.1002/bmc.5114. [PMID: 33720401]
  • Jerome R Lechien, Cosima C Hoch, Luigi A Vaira, Sven Saussez. The interest of fluticasone nasal spray in COVID-19 related anosmia is still not demonstrated. American journal of otolaryngology. 2021 Jul; 42(4):103008. doi: 10.1016/j.amjoto.2021.103008. [PMID: 33810883]
  • Chandra Veer Singh, Shraddha Jain, Sana Parveen, Prasad Deshmukh. The outcome of fluticasone nasal spray on anosmia and triamcinolone oral paste in taste dysgeusia in COVID-19 patients. American journal of otolaryngology. 2021 Jul; 42(4):103009. doi: 10.1016/j.amjoto.2021.103009. [PMID: 33846030]
  • Chandra Veer Singh, Shraddha Jain, Sana Parveen. The outcome of fluticasone nasal spray on anosmia and triamcinolone oral paste in dysgeusia in COVID-19 patients. American journal of otolaryngology. 2021 May; 42(3):102892. doi: 10.1016/j.amjoto.2020.102892. [PMID: 33493729]
  • Mohamed H Desoqi, Hossam S El-Sawy, Elsayed Kafagy, Mamdouh Ghorab, Shadeed Gad. Fluticasone propionate-loaded solid lipid nanoparticles with augmented anti-inflammatory activity: optimisation, characterisation and pharmacodynamic evaluation on rats. Journal of microencapsulation. 2021 May; 38(3):177-191. doi: 10.1080/02652048.2021.1887383. [PMID: 33583315]
  • Deepa K Ingawale, Satish K Mandlik, Snehal S Patel. Hecogenin and fluticasone combination attenuates TNBS-induced ulcerative colitis in rats via downregulation of pro-inflammatory mediators and oxidative stress. Immunopharmacology and immunotoxicology. 2021 Apr; 43(2):160-170. doi: 10.1080/08923973.2021.1872617. [PMID: 33435764]
  • M A Rahman, M N Hasan, M A Rahim, S Ahmed, S P Munni, M K Adhikari, M J Uddin, K M Saif-Ur-Rahman. Glycaemic Status of Asthma Patients Using Inhaled Fluticasone. Mymensingh medical journal : MMJ. 2021 Apr; 30(2):274-280. doi: NULL. [PMID: 33830103]
  • Megan L Zilla, Christian Keetch, Gretchen Mitchell, Jeffery McBreen, Michael R Shurin, Sarah E Wheeler. SARS-CoV-2 Serologic Immune Response in Exogenously Immunosuppressed Patients. The journal of applied laboratory medicine. 2021 03; 6(2):486-490. doi: 10.1093/jalm/jfaa232. [PMID: 33367709]
  • Peter Daley-Yates, Noushin Brealey, Sebin Thomas, Daren Austin, Shaila Shabbir, Tim Harrison, Dave Singh, Neil Barnes. Therapeutic index of inhaled corticosteroids in asthma: A dose-response comparison on airway hyperresponsiveness and adrenal axis suppression. British journal of clinical pharmacology. 2021 02; 87(2):483-493. doi: 10.1111/bcp.14406. [PMID: 32484940]
  • Michael Verschoor-Kirss, Elizabeth A Rozanski, Claire R Sharp, Trisha J Oura, Ashley Egan, Perry Bain, Joyce Knoll. Treatment of naturally occurring asthma with inhaled fluticasone or oral prednisolone: A randomized pilot trial. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2021 Jan; 85(1):61-67. doi: . [PMID: 33390654]
  • Akira Nakazono, Yuji Nakamaru, Mahnaz Ramezanpour, Takeshi Kondo, Masashi Watanabe, Shigetsugu Hatakeyama, Shogo Kimura, Aya Honma, P J Wormald, Sarah Vreugde, Masanobu Suzuki, Akihiro Homma. Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells. Frontiers in cellular and infection microbiology. 2021; 11(?):655666. doi: 10.3389/fcimb.2021.655666. [PMID: 33981629]
  • Gail M Comer, Mark A Bush, Evan S Dellon, Mark T Marino. Effect of Food Intake and Body Position on the Pharmacokinetics of Swallowed APT-1011, a Fluticasone Orally Disintegrating Tablet, in Healthy Adult Volunteers. Journal of clinical pharmacology. 2020 06; 60(6):734-743. doi: 10.1002/jcph.1572. [PMID: 31943257]
  • Joana Figueiredo, Margarida Serrado, Nikita Khmelinskii, Sónia do Vale. Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir. BMJ case reports. 2020 May; 13(5):. doi: 10.1136/bcr-2019-233712. [PMID: 32467117]
  • Johanna Eriksson, Erik Sjögren, Hans Lennernäs, Helena Thörn. Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption. The AAPS journal. 2020 05; 22(3):71. doi: 10.1208/s12248-020-00456-x. [PMID: 32394314]
  • Deepa K Ingawale, Satish K Mandlik, Snehal S Patel. Combination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model. Immunopharmacology and immunotoxicology. 2020 Apr; 42(2):128-137. doi: 10.1080/08923973.2020.1728541. [PMID: 32070162]
  • Jingyi Zhao, Xinyu Yan, Jianqing Gai, Jinshuai Han, Hong Zhang, Hui Luo, Shaoting Huang, Junge Wang. Efficacy of Bimin decoction for patients with perennial allergic rhinitis: an open-label non-inferiority randomized controlled trial. Trials. 2019 Dec; 20(1):802. doi: 10.1186/s13063-019-3763-z. [PMID: 31888713]
  • Tao-Tao Fu, Zhao-Qing Cong, Yun Zhao, Wei-Ya Chen, Chun-Yu Liu, Ying Zheng, Fei-Fei Yang, Yong-Hong Liao. Fluticasone propionate nanosuspensions for sustained nebulization delivery: An in vitro and in vivo evaluation. International journal of pharmaceutics. 2019 Dec; 572(?):118839. doi: 10.1016/j.ijpharm.2019.118839. [PMID: 31715359]
  • Omar Usmani, Nicolas Roche, Jonathan Marshall, Helen Danagher, David Price. An innovative corticosteroid/long-acting β2-agonist breath-triggered inhaler: facilitating lung delivery of fluticasone propionate/formoterol fumarate for the treatment of asthma. Expert opinion on drug delivery. 2019 12; 16(12):1367-1380. doi: 10.1080/17425247.2019.1689957. [PMID: 31752560]
  • Yan Li, Huafang Li, Yucheng Sheng, Xin Du, Yuhui Yao, Xian Luo, Peiming Ma. Pharmacokinetics of Single and Repeat Doses of Fluticasone Furoate/Umeclidinium/Vilanterol in Healthy Chinese Adults. Clinical pharmacology in drug development. 2019 08; 8(6):721-733. doi: 10.1002/cpdd.626. [PMID: 30427594]
  • Syedsaoud Zaidi, Mong-Jen Chen, Daniel T Lee, Elsa Neubart, Pär Ewing, Anna Miller-Larsson, Günther Hochhaus. Fetal Concentrations of Budesonide and Fluticasone Propionate: a Study in Mice. The AAPS journal. 2019 04; 21(4):53. doi: 10.1208/s12248-019-0313-2. [PMID: 30993489]
  • Alan Getgood, Aad Dhollander, Amanda Malone, James Price, James Helliwell. Pharmacokinetic Profile of Intra-articular Fluticasone Propionate Microparticles in Beagle Dog Knees. Cartilage. 2019 04; 10(2):139-147. doi: 10.1177/1947603517723687. [PMID: 28786292]
  • Mireille Hassoun, Maria Malmlöf, Otto Scheibelhofer, Abhinav Kumar, Sukhi Bansal, Ewa Selg, Mattias Nowenwik, Per Gerde, Snezana Radivojev, Amrit Paudel, Sumit Arora, Ben Forbes. Use of PBPK Modeling To Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products. Molecular pharmaceutics. 2019 03; 16(3):1245-1254. doi: 10.1021/acs.molpharmaceut.8b01200. [PMID: 30640475]
  • Denise Wayne, Harald Iverson, Michael Gillespie, Edward Hellriegel, Calvin Small. Bioequivalence of fluticasone propionate and salmeterol (FS) given by the FS Spiromax® and Seretide Accuhaler® systems
. International journal of clinical pharmacology and therapeutics. 2019 Jan; 57(1):43-54. doi: 10.5414/cp203216. [PMID: 30431426]
  • Hui Wang, Penny Tan, David Barona, Grace Li, Susan Hoe, David Lechuga-Ballesteros, David S Nobes, Reinhard Vehring. Characterization of the suspension stability of pharmaceuticals using a shadowgraphic imaging method. International journal of pharmaceutics. 2018 Sep; 548(1):128-138. doi: 10.1016/j.ijpharm.2018.06.053. [PMID: 29959088]
  • Jean Bousquet, Eli O Meltzer, Peter Couroux, Arkady Koltun, Ferdinand Kopietz, Ullrich Munzel, Hans Christian Kuhl, Duc Tung Nguyen, Anne Marie Salapatek, David Price. Onset of Action of the Fixed Combination Intranasal Azelastine-Fluticasone Propionate in an Allergen Exposure Chamber. The journal of allergy and clinical immunology. In practice. 2018 Sep; 6(5):1726-1732.e6. doi: 10.1016/j.jaip.2018.01.031. [PMID: 29425904]
  • Ole D Wolthers, Sabine Mersmann, Sanjeeva Dissanayake. A Pilot Study of the Normative Range of Overnight Urinary Free Cortisol Corrected for Creatinine in Children. Clinical drug investigation. 2018 Apr; 38(4):313-318. doi: 10.1007/s40261-017-0609-x. [PMID: 29256049]
  • Vishal S Patel, Evan Walgama, Alkis Psaltis, Francois Lavigne, Steven D Pletcher, Peter H Hwang. Biocompatibility and pharmacokinetics of fluticasone-eluting sinus implant in a rabbit model. American journal of rhinology & allergy. 2017 Nov; 31(6):382-388. doi: 10.2500/ajra.2017.31.4481. [PMID: 29122083]
  • Erika Amore, Maria Ferraro, Maria Letizia Manca, Mark Gjomarkaj, Gaetano Giammona, Elisabetta Pace, Maria Luisa Bondì. Mucoadhesive solid lipid microparticles for controlled release of a corticosteroid in the chronic obstructive pulmonary disease treatment. Nanomedicine (London, England). 2017 Oct; 12(19):2287-2302. doi: 10.2217/nnm-2017-0072. [PMID: 28868971]
  • Gwijde F J P M Adriaensen, Keng-Hua Lim, Wytske J Fokkens. Safety and efficacy of a bioabsorbable fluticasone propionate-eluting sinus dressing in postoperative management of endoscopic sinus surgery: a randomized clinical trial. International forum of allergy & rhinology. 2017 08; 7(8):813-820. doi: 10.1002/alr.21963. [PMID: 28558147]
  • Eric A Pasman, Theresa A Heifert, Cade M Nylund. Esophageal squamous papillomas with focal dermal hypoplasia and eosinophilic esophagitis. World journal of gastroenterology. 2017 Mar; 23(12):2246-2250. doi: 10.3748/wjg.v23.i12.2246. [PMID: 28405153]
  • Lin Lin, Zhongchun Chen, Yitan Cao, Guangbin Sun. Normal saline solution nasal-pharyngeal irrigation improves chronic cough associated with allergic rhinitis. American journal of rhinology & allergy. 2017 Mar; 31(2):96-104. doi: 10.2500/ajra.2017.31.4418. [PMID: 28452705]
  • Ludger Klimek, Sophia C Poletti, Annette Sperl, Magdalena Spielhaupter, Cornel Bardenhewer, Joaquim Mullol, Karl Hörmann, Thomas Hummel. Olfaction in patients with allergic rhinitis: an indicator of successful MP-AzeFlu therapy. International forum of allergy & rhinology. 2017 03; 7(3):287-292. doi: 10.1002/alr.21877. [PMID: 27888645]
  • Sneha G Nair, Daxesh P Patel, Mallika Sanyal, Puran Singhal, Pranav S Shrivastav. Simultaneous analysis of glucocorticosteroid fluticasone propionate and its metabolite fluticasone propionate 17β-carboxylic acid in human plasma by UPLC-MS/MS at sub pg/mL level. Journal of pharmaceutical and biomedical analysis. 2017 Feb; 135(?):1-7. doi: 10.1016/j.jpba.2016.12.008. [PMID: 27987390]
  • D K Ingawale, S S Patel. Anti-Inflammatory Potential of Hecogenin in Experimental Animals: Possible Involvement of Inflammatory Cytokines and Myeloperoxidase. Drug research. 2016 Dec; 66(12):644-656. doi: 10.1055/s-0042-113184. [PMID: 27684191]
  • Alejandra Cimato, Andres Hoyos Obando, Graciela Facorro, María Martínez Sarrasague. Analysis of the structure and surfactant activity of novel formulations containing exogenous pulmonary surfactant and glucocorticoids. Respiratory physiology & neurobiology. 2016 11; 233(?):33-40. doi: 10.1016/j.resp.2016.07.009. [PMID: 27476933]
  • Yehonatan Pasternak, Havatzelet Yarden-Bilavsky, Yona Kodman, Meira Zoldan, Hannah Tamary, Shai Ashkenazi. Inhaled corticosteroids increase blood neutrophil count by decreasing the expression of neutrophil adhesion molecules Mac-1 and L-selectin. The American journal of emergency medicine. 2016 Oct; 34(10):1977-1981. doi: 10.1016/j.ajem.2016.07.003. [PMID: 27498916]
  • Shima Vazifehkah, Mohammad Reza Shams-Ardekani, Mohammad Kamalinejad, Seyed Mousa Saderhossein, Hamed Hosseini, Seyed Mohammad Shams, Shirin Abbassi, Sareh Eghtesad, Babak Saedi. Evaluation of a novel natural drop for treatment of chronic rhinosinusitis without nasal polyps: a single blind randomized trial. International forum of allergy & rhinology. 2016 09; 6(9):943-9. doi: 10.1002/alr.21785. [PMID: 27218285]
  • George Marshall. Falling up stairs. Australian family physician. 2016 Sep; 45(9):658-9. doi: NULL. [PMID: 27606369]
  • Andrzej Emeryk, Rabih Klink, Tammy McIver, Prashant Dalvi. A 12-week open-label, randomized, controlled trial and 24-week extension to assess the efficacy and safety of fluticasone propionate/formoterol in children with asthma. Therapeutic advances in respiratory disease. 2016 08; 10(4):324-37. doi: 10.1177/1753465816646320. [PMID: 27185164]
  • Anne Kotaniemi-Syrjänen, Weronika Delezuch, L Pekka Malmberg, Kari Punnonen, Irma H Matinlauri, Anna S Pelkonen, Mika J Mäkelä. Serum soluble TH cell activity markers and high-sensitivity C-reactive protein in multiple-trigger wheezers. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2016 08; 117(2):196-8. doi: 10.1016/j.anai.2016.05.022. [PMID: 27291855]
  • Roland Buhl, Stephanie Korn, Andrew Menzies-Gow, Michel Aubier, Kenneth R Chapman, Giorgio W Canonica, César Picado, Nicolas Martin, Ramon Aguiar Escobar, Stephan Korom, Nicola A Hanania. Assessing biomarkers in a real-world severe asthma study (ARIETTA). Respiratory medicine. 2016 06; 115(?):7-12. doi: 10.1016/j.rmed.2016.04.001. [PMID: 27215497]
  • Vincent C H Chung, Xinyin Wu, Polly H X Ma, Robin S T Ho, Simon K Poon, David S Hui, Samuel Y S Wong, Justin C Y Wu. Chinese Herbal Medicine and Salmeterol and Fluticasone Propionate for Chronic Obstructive Pulmonary Disease: Systematic Review and Network Meta-Analysis. Medicine. 2016 May; 95(20):e3702. doi: 10.1097/md.0000000000003702. [PMID: 27196484]
  • Apinya Bee Vutikullird, Michael Gillespie, Sharon Song, Jonathan Steinfeld. Pharmacokinetics, Safety, and Tolerability of a New Fluticasone Propionate Multidose Dry Powder Inhaler Compared With Fluticasone Propionate Diskus(®) in Healthy Adults. Journal of aerosol medicine and pulmonary drug delivery. 2016 Apr; 29(2):207-14. doi: 10.1089/jamp.2015.1226. [PMID: 26624976]
  • Makoto Hoshino, Junichi Ohtawa, Kenta Akitsu. Effect of treatment with inhaled corticosteroid on serum periostin levels in asthma. Respirology (Carlton, Vic.). 2016 Feb; 21(2):297-303. doi: 10.1111/resp.12687. [PMID: 26607392]
  • Mara Lelii, Nicola Principi, Susanna Esposito. Transient symptomatic hyperglycaemia secondary to inhaled fluticasone propionate in a young child. BMC pulmonary medicine. 2016 Jan; 16(?):9. doi: 10.1186/s12890-016-0170-z. [PMID: 26758622]
  • Masako To, Yuta Kono, Seiko Soeda, Hiroko Hara, Kosuke Araki, Hirohisa Kishi, Yasuo To. A case of IgG4-related bronchial disease successfully treated with inhaled corticosteroids. The journal of allergy and clinical immunology. In practice. 2016 Jan; 4(1):168-70. doi: 10.1016/j.jaip.2015.08.013. [PMID: 26441152]
  • Rana Keyhanmanesh, Saeideh Saadat, Mostafa Mohammadi, Amir-Ali Shahbazfar, Maryam Fallahi. The Protective Effect of α-Hederin, the Active Constituent of Nigella sativa, on Lung Inflammation and Blood Cytokines in Ovalbumin Sensitized Guinea Pigs. Phytotherapy research : PTR. 2015 Nov; 29(11):1761-7. doi: 10.1002/ptr.5429. [PMID: 26292851]
  • Adelina Gavrila, Latifa Chachi, Omar Tliba, Christopher Brightling, Yassine Amrani. Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells. American journal of respiratory cell and molecular biology. 2015 Nov; 53(5):728-37. doi: 10.1165/rcmb.2014-0477oc. [PMID: 25897650]
  • Dave Singh, Leonard Siew, Jared Christensen, Jonathan Plumb, Graham W Clarke, Steve Greenaway, Christelle Perros-Huguet, Nick Clarke, Iain Kilty, Lisa Tan. Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects. European journal of clinical pharmacology. 2015 Oct; 71(10):1175-84. doi: 10.1007/s00228-015-1920-1. [PMID: 26265232]
  • Anita Umerska, Celia R A Mouzouvi, André Bigot, Patrick Saulnier. Formulation and nebulization of fluticasone propionate-loaded lipid nanocarriers. International journal of pharmaceutics. 2015 Sep; 493(1-2):224-32. doi: 10.1016/j.ijpharm.2015.07.008. [PMID: 26183331]
  • Michael Gillespie, Sharon Song, Jonathan Steinfeld. Pharmacokinetics of fluticasone propionate multidose, inhalation-driven, novel, dry powder inhaler versus a prevailing dry powder inhaler and a metered-dose inhaler. Allergy and asthma proceedings. 2015 Sep; 36(5):365-71. doi: 10.2500/aap.2015.36.3889. [PMID: 26314817]
  • Benjamin Weber, Guenther Hochhaus. A Systematic Analysis of the Sensitivity of Plasma Pharmacokinetics to Detect Differences in the Pulmonary Performance of Inhaled Fluticasone Propionate Products Using a Model-Based Simulation Approach. The AAPS journal. 2015 Jul; 17(4):999-1010. doi: 10.1208/s12248-015-9768-y. [PMID: 25933600]
  • Evan S Dellon, Spencer Rusin, Jessica H Gebhart, Shannon Covey, Leana L Higgins, RoseMary Beitia, Olga Speck, Kimberly Woodward, John T Woosley, Nicholas J Shaheen. Utility of a Noninvasive Serum Biomarker Panel for Diagnosis and Monitoring of Eosinophilic Esophagitis: A Prospective Study. The American journal of gastroenterology. 2015 Jun; 110(6):821-7. doi: 10.1038/ajg.2015.57. [PMID: 25781367]
  • Katarzyna Grzela, Wioletta Zagorska, Alicja Krejner, Malgorzata Litwiniuk, Anna Zawadzka-Krajewska, Aleksandra Banaszkiewicz, Marek Kulus, Tomasz Grzela. Prolonged Treatment with Inhaled Corticosteroids does not Normalize High Activity of Matrix Metalloproteinase-9 in Exhaled Breath Condensates of Children with Asthma. Archivum immunologiae et therapiae experimentalis. 2015 Jun; 63(3):231-7. doi: 10.1007/s00005-015-0328-z. [PMID: 25650123]
  • Trohadio Munoz, Mathilde Leclere, Daniel Jean, Jean-Pierre Lavoie. Serum cortisol concentration in horses with heaves treated with fluticasone proprionate over a 1 year period. Research in veterinary science. 2015 Feb; 98(?):112-4. doi: 10.1016/j.rvsc.2014.12.013. [PMID: 25577545]
  • Cornelia Egger, Christian Lupinek, Robin Ristl, Patrick Lemell, Friedrich Horak, Petra Zieglmayer, Susanne Spitzauer, Rudolf Valenta, Verena Niederberger. Effects of nasal corticosteroids on boosts of systemic allergen-specific IgE production induced by nasal allergen exposure. PloS one. 2015; 10(2):e0114991. doi: 10.1371/journal.pone.0114991. [PMID: 25705889]
  • Maria Luisa Bondì, Maria Ferraro, Serena Di Vincenzo, Stefania Gerbino, Gennara Cavallaro, Gaetano Giammona, Chiara Botto, Mark Gjomarkaj, Elisabetta Pace. Effects in cigarette smoke stimulated bronchial epithelial cells of a corticosteroid entrapped into nanostructured lipid carriers. Journal of nanobiotechnology. 2014 Nov; 12(?):46. doi: 10.1186/s12951-014-0046-4. [PMID: 25432702]
  • Marti Antilla, Fábio Castro, Álvaro Cruz, Adalberto Rubin, Nelson Rosário, Rafael Stelmach. Efficacy and safety of the single-capsule combination of fluticasone/formoterol in patients with persistent asthma: a non-inferiority trial. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2014 Nov; 40(6):599-608. doi: 10.1590/s1806-37132014000600003. [PMID: 25610500]
  • Jian-hua Xu, Bin Xu, Yan-qing Deng. [Efficacy on chronic obstructive pulmonary disease at stable stage treated with cutting method and western medication]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2014 Oct; 34(10):951-5. doi: NULL. [PMID: 25543420]
  • Ernesto Crisafulli, Mónica Guerrero, Rosario Menéndez, Arturo Huerta, Raquel Martinez, Alexandra Gimeno, Néstor Soler, Antoni Torres. Inhaled corticosteroids do not influence the early inflammatory response and clinical presentation of hospitalized subjects with COPD exacerbation. Respiratory care. 2014 Oct; 59(10):1550-9. doi: 10.4187/respcare.03036. [PMID: 25074943]
  • Christoph Schlag, Sabrina Pfefferkorn, Knut Brockow, Bernhard Haller, Julia Slotta-Huspenia, Stephan Schulz, Alexander von Werder, Johannes Ring, Roland M Schmid, Monther Bajbouj. Serum eosinophil cationic protein is superior to mast cell tryptase as marker for response to topical corticosteroid therapy in eosinophilic esophagitis. Journal of clinical gastroenterology. 2014 Aug; 48(7):600-6. doi: 10.1097/01.mcg.0000436439.67768.8d. [PMID: 24177377]
  • Laurie A Lee, Richard Sterling, Jorge Máspero, Diane Clements, Anna Ellsworth, Soren Pedersen. Growth velocity reduced with once-daily fluticasone furoate nasal spray in prepubescent children with perennial allergic rhinitis. The journal of allergy and clinical immunology. In practice. 2014 Jul; 2(4):421-7. doi: 10.1016/j.jaip.2014.04.008. [PMID: 25017530]
  • F J Stokes, L M Bailey, A Ganguli, A S Davison. Assessment of endogenous, oral and inhaled steroid cross-reactivity in the Roche cortisol immunoassay. Annals of clinical biochemistry. 2014 Jul; 51(Pt 4):503-6. doi: 10.1177/0004563213509793. [PMID: 24150482]
  • Virginia Norris, Claire Ambery, Trevor Riley. Pharmacokinetics and pharmacodynamics of GSK961081, a novel inhaled muscarinic antagonist β2 -agonist, and fluticasone propionate administered alone, concurrently and as a combination blend formulation in healthy volunteers. Clinical pharmacology in drug development. 2014 07; 3(4):305-13. doi: 10.1002/cpdd.105. [PMID: 27128837]
  • Nathan Rabinovitch, David T Mauger, Nichole Reisdorph, Ronina Covar, Jonathan Malka, Robert F Lemanske, Wayne J Morgan, Theresa W Guilbert, Robert S Zeiger, Leonard B Bacharier, Stanley J Szefler. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. The Journal of allergy and clinical immunology. 2014 Feb; 133(2):350-6. doi: 10.1016/j.jaci.2013.07.039. [PMID: 24084071]
  • Sirpa Leivo-Korpela, Lauri Lehtimäki, Mari Hämälainen, Katriina Vuolteenaho, Lea Kööbi, Ritva Järvenpää, Hannu Kankaanranta, Seppo Saarelainen, Eeva Moilanen. Adipokines NUCB2/nesfatin-1 and visfatin as novel inflammatory factors in chronic obstructive pulmonary disease. Mediators of inflammation. 2014; 2014(?):232167. doi: 10.1155/2014/232167. [PMID: 24891763]
  • Sirpa Leivo-Korpela, Lauri Lehtimäki, Katriina Vuolteenaho, Riina Nieminen, Lea Kööbi, Ritva Järvenpää, Hannu Kankaanranta, Seppo Saarelainen, Eeva Moilanen. Adiponectin is associated with dynamic hyperinflation and a favourable response to inhaled glucocorticoids in patients with COPD. Respiratory medicine. 2014 Jan; 108(1):122-8. doi: 10.1016/j.rmed.2013.08.016. [PMID: 24135487]
  • Elisabetta Pace, Maria Ferraro, Serena Di Vincenzo, Chiara Cipollina, Stefania Gerbino, Diego Cigna, Valentina Caputo, Rossella Balsamo, Luigi Lanata, Mark Gjomarkaj. Comparative cytoprotective effects of carbocysteine and fluticasone propionate in cigarette smoke extract-stimulated bronchial epithelial cells. Cell stress & chaperones. 2013 Nov; 18(6):733-43. doi: 10.1007/s12192-013-0424-0. [PMID: 23580157]
  • Ann Allen, Isabelle Schenkenberger, Roopa Trivedi, Jeremy Cole, Wesley Hicks, Nadeem Gul, Loretta Jacques. Inhaled fluticasone furoate/vilanterol does not affect hypothalamic-pituitary-adrenal axis function in adolescent and adult asthma: randomised, double-blind, placebo-controlled study. The clinical respiratory journal. 2013 Oct; 7(4):397-406. doi: 10.1111/crj.12026. [PMID: 23578031]
  • Prasad Muley, Monali Shah, Arti Muley. Safety of inhaled fluticasone propionate therapy for pediatric asthma - a systematic review. Current drug safety. 2013 Jul; 8(3):186-94. doi: 10.2174/15748863113089990038. [PMID: 23859431]
  • Bobby P Gray, Simon Biddle, Clive M Pearce, Lynn Hillyer. Detection of fluticasone propionate in horse plasma and urine following inhaled administration. Drug testing and analysis. 2013 May; 5(5):306-14. doi: 10.1002/dta.1329. [PMID: 22514113]
  • Sharon Kramer, Bart L Rottier, Rob J P M Scholten, Nicole Boluyt. Ciclesonide versus other inhaled corticosteroids for chronic asthma in children. The Cochrane database of systematic reviews. 2013 Feb; ?(2):CD010352. doi: 10.1002/14651858.cd010352. [PMID: 23450613]
  • Allena J Ji, Dawei Zhou, Shu Zhang, Monica Ann Cawley, Xinping Fang, Jinn Wu. Ultrasensitive and automated 1 pg/ml fluticasone propionate assay in human plasma using LC-MS/MS. Bioanalysis. 2013 Feb; 5(4):423-35. doi: 10.4155/bio.12.338. [PMID: 23414376]
  • Izabela Kupryś-Lipińska, Damian Tworek, Francis Vanderbist, Małgorzata Bocheńska-Marciniak, Piotr Kuna. Efficacy and safety of a 12-week therapy with a new formulation of fluticasone propionate at doses of 125 and 250 μg administered through a new generation cyclohaler twice daily, in comparison to fluticasone propionate 500 μg dry powder inhaler twice daily in patients with moderate asthma. Pneumonologia i alergologia polska. 2013; 81(6):527-36. doi: NULL. [PMID: 24142782]
  • Marika Melamies, Outi Vainio, Thomas Spillmann, Jouni Junnila, Minna M Rajamäki. Endocrine effects of inhaled budesonide compared with inhaled fluticasone propionate and oral prednisolone in healthy Beagle dogs. Veterinary journal (London, England : 1997). 2012 Dec; 194(3):349-53. doi: 10.1016/j.tvjl.2012.04.029. [PMID: 22640563]
  • Mathilde Leclere, Anouk Lavoie-Lamoureux, Philippe Joubert, Fabien Relave, Emilie Lanctot Setlakwe, Guy Beauchamp, Christian Couture, James G Martin, Jean-Pierre Lavoie. Corticosteroids and antigen avoidance decrease airway smooth muscle mass in an equine asthma model. American journal of respiratory cell and molecular biology. 2012 Nov; 47(5):589-96. doi: 10.1165/rcmb.2011-0363oc. [PMID: 22721832]
  • John B Hagan, Brian C Netzel, Marc R Matthews, Nichole L Korpi-Steiner, Ravinder J Singh. Urinary fluticasone propionate-17beta-carboxylic acid to assess asthma therapy adherence. Allergy and asthma proceedings. 2012 Jul; 33(4):e35-9. doi: 10.2500/aap.2012.33.3568. [PMID: 22856629]
  • Nan-Chang Song, Jin-Bao He, Han-Bin Xu, Ji-Feng Wu. [Comparative study on effect of acupoint heat-sensitive moxibustion and Seretide on the symptoms of bronchial asthma at chronic persistent stage]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2012 Jul; 32(7):593-6. doi: ". [PMID: 22997785]
  • Hartmut Derendorf, Ullrich Munzel, Ursula Petzold, Joachim Maus, Hermann Mascher, Robert Hermann, Jean Bousquet. Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29-02, a novel aqueous nasal spray. British journal of clinical pharmacology. 2012 Jul; 74(1):125-33. doi: 10.1111/j.1365-2125.2012.04222.x. [PMID: 22356350]
  • Keivan Gohari Moghaddam, Negin Rashidi, Hamidreza Aghaei Meybodi, Nader Rezaie, Mahdi Montazeri, Ramin Heshmat, Zohreh Annabestani. The effect of inhaled corticosteroids on hypothalamic-pituitary-adrenal axis. Indian journal of pharmacology. 2012 May; 44(3):314-8. doi: 10.4103/0253-7613.96300. [PMID: 22701238]
  • Luigi Silvestro, Simona Rizea Savu, Simona Nicoleta Savu, Ariana Tudoroniu, Isabela Tarcomnicu. Development of a sensitive method for simultaneous determination of fluticasone propionate and salmeterol in plasma samples by liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC. 2012 May; 26(5):627-35. doi: 10.1002/bmc.1708. [PMID: 22577660]
  • Abolhasan Halvani, Fatemeh Tahghighi, Hossein Hadi Nadooshan. Evaluation of correlation between airway and serum inflammatory markers in asthmatic patients. Lung India : official organ of Indian Chest Society. 2012 Apr; 29(2):143-6. doi: 10.4103/0970-2113.95317. [PMID: 22628929]
  • José L López-Campos, Elena Arellano, Carmen Calero, Ana Delgado, Eduardo Márquez, Pilar Cejudo, Francisco Ortega, Francisco Rodríguez-Panadero, Ana Montes-Worboys. Determination of inflammatory biomarkers in patients with COPD: a comparison of different assays. BMC medical research methodology. 2012 Mar; 12(?):40. doi: 10.1186/1471-2288-12-40. [PMID: 22463705]
  • Ricardo Martins Duarte Byrro, Isabela Costa César, Fabiana Fernandes de Santana e Silva Cardoso, Iram Moreira Mundim, Leonardo de Souza Teixeira, Ricardo Rodrigues Bonfim, Sandro Antônio Gomes, Gerson Antônio Pianetti. A rapid and sensitive HPLC-APCI-MS/MS method determination of fluticasone in human plasma: application for a bioequivalency study in nasal spray formulations. Journal of pharmaceutical and biomedical analysis. 2012 Mar; 61(?):38-43. doi: 10.1016/j.jpba.2011.11.018. [PMID: 22178434]
  • David A Lomas, David A Lipson, Bruce E Miller, Lisa Willits, Oliver Keene, Helen Barnacle, Neil C Barnes, Ruth Tal-Singer. An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease. Journal of clinical pharmacology. 2012 Mar; 52(3):416-24. doi: 10.1177/0091270010397050. [PMID: 22090363]
  • Shao Lin, Jean Pierre W Munsie, Michele L Herdt-Losavio, Charlotte M Druschel, Kimberly Campbell, Marilyn L Browne, Paul A Romitti, Richard S Olney, Erin M Bell. Maternal asthma medication use and the risk of selected birth defects. Pediatrics. 2012 Feb; 129(2):e317-24. doi: 10.1542/peds.2010-2660. [PMID: 22250027]